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This section provides an overview for paraformaldehyde as well as their applications and principles. Also, please take a look at the list of 19 paraformaldehyde manufacturers and their company rankings. Here are the top-ranked paraformaldehyde companies as of December, 2024: 1.Paragon Chemicals, 2.KANTO CHEMICAL CO.,INC., 3.Junsei Chemical Co.,Ltd..
Table of Contents
Paraformaldehyde, an organic compound, results from the dehydration and polymerization of formaldehyde. This linear polymer is recognized by its CAS registration number 30525-89-4 and has the chemical formula (CH2O)n. Also known as "paraform" and "1,3,5-trioxane," paraformaldehyde belongs to the class of polymers known as polyacetals or polyoxymethylenes, characterized by the oxymethylene (-CH2O-) structure in their units. Due to its potent effects, it is regulated as a powerful drug under related laws, highlighting its significant toxicity.
As a versatile agent, paraformaldehyde is deployed as a fumigant for pest control and disinfection. Its high reactivity makes it a preferred raw material in the synthesis of various products, including paints, adhesives, preservatives, and resins (phenolic, urea, and vinylon acetalization applications), as well as in the production of ion exchange resins, pharmaceuticals, water-resistant glues, and protein glue coagulants. Specifically, it serves as a crucial ingredient for methylol and methylene compounds, which enhance the properties of paints and adhesives by providing UV protection and improving their durability and heat resistance. Notably, methylene chloride, a primary methylene compound, is widely used as a paint stripper and remover.
This polymer, denoted as (CH2O)n, appears as a white solid (in various forms like flakes, granules, or crystalline powder) and decomposes at temperatures between 120-180°C, depending on its polymerization degree. It emits a distinct formaldehyde odor and is insoluble in water, ethanol, and ether, yet dissolves in sodium hydroxide solution. Its density stands at 1.42g/mL. Notably, paraformaldehyde can revert to formaldehyde when dissolved in water or upon heating, highlighting its dynamic nature as it releases flammable formaldehyde gas when dried.
Available for research and industrial applications, paraformaldehyde is often utilized as a crosslinking and immobilization reagent due to its ability to convert back to formaldehyde upon heating with sodium hydroxide. Its laboratory forms include manageable quantities like 100g, 500g, 1kg, and 2kg, facilitating easy handling. Industrially, it's packaged in larger quantities, such as 20kg paper bags or flexible containers, supporting its use in manufacturing paints, adhesives, fiber processing resins, and phenolic resins.
Paraformaldehyde naturally precipitates as a white solid from formaldehyde solutions, especially upon cooling. Formaldehyde, its monomer, is typically produced by the air oxidation of methanol in the presence of a catalyst or by the carbonization of calcium formate.
Recognized as a flammable and combustible solid, paraformaldehyde poses risks of dust explosions when its particles are airborne. It can react vigorously with oxidizing agents, acids, and bases, potentially leading to the generation of heat or the release of formaldehyde gas. Its ingestion or inhalation is harmful, causing skin and eye irritation, along with possible lung damage.
Given its hazards, paraformaldehyde is subject to stringent regulations. It is classified as a combustible substance and is also designated as a deleterious substance under various health and safety laws. Compliance with these regulations is crucial for its safe handling and use.
*Including some distributors, etc.
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Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
Junsei Chemical Co. Ltd., established in 1948 and headquartered in Tokyo, Japan, is a manufacturer of chemical reagents and chemical products, including commissioned synthesis of chemical products. Some of the products it makes include Sodium chloride solution, concentrated glycerin, calcium chloride, ascorbic acid, and nitric acid. The chemical products have a wide range of applications and can be used in pathological examination, as food additives, for analysis, and in the pharmaceutical industry. All its plants, including its research institute, are ISO4001 and ISO9001 certified, while its Saitama and Ibaraki plants are equipped with buildings that comply with GMP.
Kishida Chemical Co. Ltd., established in 1924 and headquartered in Osaka, Japan, is a manufacturer of reagents and high-purity chemicals and also does drug discovery support activities. Its product portfolio includes fine chemicals, research chemicals, ionic liquid, organic micro-analytical reagents, and chemical reagents for analysis. The products support several industries, including reagent business, battery material, drug discovery, and life science. The company is ISO 14001 certified and supplies several companies worldwide, including Meterion Advanced Chemicals Inc., Acros Organics, ChemBridge Corporation, Decon Laboratories, and InerBioScreen Ltd.
Mitsubishi Gas Chemical Company Inc., established in 1918 and headquartered in Tokyo, Japan, is a chemical manufacturer that makes basic and fine chemicals and functional materials. The company has two business divisions, namely basic chemicals and functional chemicals, and its product portfolio includes electronic industry cleaning agents, MMA derivatives, hydrogen peroxide, xylene separation products, and laminated materials for printed circuit boards. In 1981, the company took the first step towards geothermal power development, and today, it is involved in geothermal power projects in five locations, including the 50,000-kilowatt Sumikawa Geothermal Power Plant, where it commenced operations in 1995.
Merck, started in 1668 and based in Darmstadt, Germany, is a supplier of solutions and services for research, development, and manufacture of pharmaceutical and biotechnological drug therapies. The company serves the life science industry and has a broad portfolio of 300,000 products, including biopharmaceutical manufacturing, industrial microbiology, reagent, life science research, and water purification products. It is available in 66 countries, brings together six brands, and has several ISO certifications, including ISO 13485, ISO 14001, ISO 13485, and ISO 50001.
Chemanol is a manufacturer of chemicals that was established in 1989, and is headquartered in Al Jubail, Saudi Arabia. Chemanol produces a wide range of specialty chemicals, including catalysts, additives, surfactants, polymers, and pharmaceuticals. The company's products are used by a number of industries, as diverse as agriculture, pharmaceuticals and construction, chemical, and automotive industries. Chemanol also provides a range of services to its customers, including custom synthesis, formulation of chemicals into many products, such as solutions, powders, and pellets, packaging specialty chemicals in a multiple containers, such as drums, bottles, and bags and logistics.
Celanese is an American manufacturer of chemicals and specialty materials. The company was originally founded in 1918 as the American Cellulose and Chemical Manufacturing Company before its rebrand in 1927. Based in Irving, Texas, the company produces natural polymers such as cellulose acetate and intermediate chemicals like acetyl chain, as well as food ingredients including sorbates and engineered materials comprising of Riteflex® thermoplastic polyester elastomers. These are utilized in the industrial processes of various sectors, including food and beverages, and energy production. Celanese has served several large corporations operating internationally, including the Coca-Cola Company, Shell Plc, and the L’Oreal cosmetics company.
Fengchen Group Co., LTD is based in Qingdao, China. The company is a manufacturer and supplier of speciality chemicals for several industries around the world including natural resources, hydrogeology, drilling, geophysics, and environmental & geotechnical services. The company’s chemical product categories include APIs, amino acids, micronutrients, package materials, and enzymes. The company also offers services including specialized transportation, samples of compounds, shipping documents needed for pharmaceutical products, and international customs support.
Nacalai Tesque Inc., founded in 1846 and headquartered in Kyoto, Japan, is a manufacturer of research chemicals, fine chemicals, diagnostics, and the related instruments. Some of its products include cytokines, nucleic acid electrophoresis, cell dissociation reagents, and sialic acid-related products, and it also offers custom and bulk service for bulk reagents and cell culture media. The company has more than 50 domestic distributors and several worldwide, including Asia, the Middle East, Oceania, Europe, and Africa. It is ISO 9001 and ISO 9002 certified, while the Kyoto South brand and Tesque factory are ISO 14001 certified.
RX Chemicals was founded in Mumbai, India, in 2011. RX Chemicals sells chemical-based products for many sectors including automobile, agriculture, airline, medicine, and accessories. Automobile products include carwash shampoo, compressor cleaner, and interior cleaners. Agricultural products include fungicides, herbicides, and pesticides. Airline products include exterior products such as deicing fluid, as well as interior products such as solvent cleaner. The company also provides a range of services including chemical inspection, logistics, chemical usage supervision, as well as tank cleaning.
Founded in 1981, Central Drug House Ltd. serves the scientific community via manufacturing and marketing a library of over 9,000 products to laboratory fine chemicals and dehydrated culture media with emphasis on purity and service. Examples are acids & bases, adsorbents, disinfectants, indicator papers, oils, and solvents. CDH provides bio chemicals, research chemicals, laboratory reagents, various solvents, stains & indicators, and dehydrated culture media. CDH is ISO 9001 certified and CDHs’ products are in compliance with specifications of IP, BP, USP, and EP standards.
Vizag Chemical International was founded in Andhra Pradesh, India, in 2011. Vizag Chemical International sells chemical-based products for many sectors including automotive, agriculture, airline, deodorizers, construction chemicals, boat maintenance, degreasers, detergents, drain clean products, greases, personal hygiene, lab chemicals and equipment, fuel treatment, metal treatment, tank cleaners, swimming pool and spa chemicals, scale removers, sewage chemical treatment, as well as raw chemicals. Vizag Chemical International also provides a range of services including chemical inspection, logistics, chemical usage supervision, as well as tank cleaning.
Gansu Puluowangda International Trade Co., Ltd. is a chemical supplier based in Yumen City, Gansu, China that was established in 2013. The company specializes on importing and exporting casein products, Chinese wolfberry, sunflower seeds, pesticide intermediates, pharmaceutical intermediates, dye intermediates and other wide range of chemicals for industrial and research applications. Its main products include organic chemicals, inorganic chemicals, and polymers. Some of its popular products are ethylene glycol, glycerin, and sodium hydroxide. Gansu Puluowangda also offers services such as technical support, custom synthesis, and packaging. Its products are used in many industries, including plastics, textiles, and pharmaceuticals.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | Paragon Chemicals |
18.3%
|
| 2 | KANTO CHEMICAL CO.,INC. |
9.0%
|
| 3 | Merck |
7.6%
|
| 4 | Junsei Chemical Co.,Ltd. |
7.2%
|
| 5 | Chemanol |
5.9%
|
| 6 | MITSUBISHI GAS CHEMICAL COMPANY, INC. |
5.9%
|
| 7 | Navin Chemicals |
5.5%
|
| 8 | RXChemicals |
5.2%
|
| 9 | Kishida Chemical Co.,Ltd. |
5.2%
|
| 10 | Fengchen Group Co.,Ltd |
4.5%
|
Derivation Method
The ranking is calculated based on the click share within the paraformaldehyde page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
India
|
6 | 50.0% |
|
Japan
|
5 | 41.7% |
|
China
|
1 | 8.3% |
