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This section provides an overview for l-valine as well as their applications and principles. Also, please take a look at the list of 22 l-valine manufacturers and their company rankings. Here are the top-ranked l-valine companies as of December, 2024: 1.KYOWA HAKKO BIO CO.,LTD., 2.JIGCHEM UNIVERSAL, 3.Hebei Honray Imp. & Exp. Co., Ltd..
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Okayama University Graduate School, Ph.D. (Agriculture). After working as a specially appointed Assistant Professor at Tokyo Medical and Dental University, a fluid researcher at the Okayama Prefectural Institute of Biological Sciences, and a special researcher (JSPS PD) at the Japan Society for the Promotion of Japan Science, he became independent as a freelancer.
Specializes in natural product chemistry, protein engineering, fermentation engineering, and instrumental analysis of chemicals (especially mass spectrometry chemistry).
Thesis: https://pubmed.ncbi.nlm.nih.gov/?term=HIROKAZU+USUKI
linkedin: https://www.linkedin.com/in/%E5%8D%9A%E4%B8%80-%E8%87%BC%E6%9C%A8-b83827228/
L-valine is a natural, essential amino acid found in many foods. As a branched-chain amino acid (BCAA), along with leucine and isoleucine, it plays an important role in protein synthesis. It has an isopropyl group in its side chain and exists as an L-body in proteins.
English Name: L-Valine
IUPAC Name: (2S)-2-amino-3-methylbutanoic acid
3-Letter Abbreviation: Val
1-Letter Abbreviation: V
C5H11NO2
117.15
315°C (decomposes)
Slightly soluble in water, insoluble in ethanol
Bitter
L-valine is biosynthesized in plants from pyruvic acid through a multi-step enzymatic process involving aminotransferases.
L-valine is used in strength training supplements to support muscle metabolism and provide energy during exercise.
Used in cosmetics for its moisturizing effect on the skin.
Important for fatigue relief, growth promotion, regulating nitrogen levels, and improving ammonia metabolism.
Used for amino acid supplementation in conditions like hypoproteinemia.
Reported to aid in muscle repair, liver cirrhosis improvement, and anorexia treatment.
Caused by a genetic abnormality in metabolizing BCAAs, including L-valine.
Characterized by a mutation where glutamic acid in hemoglobin is replaced by L-valine, leading to sickle-shaped erythrocytes.
Rich sources include liver, beef, chicken, peanuts, processed cheese, tuna, eggs, and milk.
*Including some distributors, etc.
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NutraCap Labs was founded in 2016 and headquartered in Atlanta, Georgia, as a manufacturer and distributor of wellness and fitness supplements. The company specialises in manufacturing Nutraceuticals/Dietary Supplements which consist of encapsulation manufacturing, sports nutrition, raw health powders and product formulations. The company offers clients contract Manufacturing, custom formulation, private labelling, brand design and distribution to help them build their brand. NutraCap Labs is a fully certified GMP compliant and FDA registered company that has a sister company, Active Wholesale USA, through which they market and sell supplements to retail stores worldwide.
Kyowa Hakko Bio Co., Ltd. was established in 2008 and is based in Tokyo, Japan, as a manufacturer of pharmaceutical raw materials and ingredients. It specializes in manufacturing bulk pharmaceuticals like citicoline, L-glutathione, and L-ornithine aspartate. It also manufactures raw materials for infusions, dietary supplements, and cosmetics, such as amino acids, peptides, oligosaccharides, and nucleic acids. The company is a subsidiary of Kirin Holdings Company and has obtained ISO 22000:2018, ISO/TS 22002-1:2009, and FSSC 22000 certifications. Its manufactured products are utilized in pharmaceuticals, nutritional supplements, industrial, and cosmetics sectors across Japan, China, the USA, Germany, and Italy.
Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
Kishida Chemical Co. Ltd., established in 1924 and headquartered in Osaka, Japan, is a manufacturer of reagents and high-purity chemicals and also does drug discovery support activities. Its product portfolio includes fine chemicals, research chemicals, ionic liquid, organic micro-analytical reagents, and chemical reagents for analysis. The products support several industries, including reagent business, battery material, drug discovery, and life science. The company is ISO 14001 certified and supplies several companies worldwide, including Meterion Advanced Chemicals Inc., Acros Organics, ChemBridge Corporation, Decon Laboratories, and InerBioScreen Ltd.
Zhejiang Shengyu Chemical Co Ltd, founded in 2005 and based in Zhejiang, China, is a manufacturer and marketer of dyes, Active Pharmaceutical Ingredients (API), and the intermediates. Some of its products include reactive dyes, cationic dyes, dye intermediates, and pharmaceutical intermediates, and it serves several industries, including textile brightening, textile printing, and plastic dyeing. The company has plants in Jiangxi Province, Inner Mongolia Autonomous Region, and Jiangsu Province, and it serves several markets, including Southeast Asia, Europe, the Middle East, the U.S.A, and North Africa.
Hebei Honray Imp. & Exp. Co., a subsidiary of the Honray Group, was established in 2012 and based in Shijiazhuang City, Hebei, China. The company is a manufacturer and exporter of Amino Acids, Sweeteners, Food Ingredients, and Vitamins. The company’s products comprise of components like Glycine, L-lysine HCL, L-lysine sulfate, and L-Phenylalanine catering to industries such as food, feed, healthcare, and cosmetics. The products are primarily distributed across markets in America, Europe, and Southeast Asia.
Hefei Home Sunshine Pharmaceutical Technology Co., Ltd, established in 2013 and headquartered in Hefei City, China, is a manufacturer specializing in both standard and custom chemical synthesis. With manufacturing facilities in Anhui, Jiangsu, Zhejiang, and Inner Mongolia, Home Sunshine Pharma offers a range of products, including active pharmaceutical ingredients (APIs), intermediates, fine chemicals, coenzymes, and nucleotides. As an ISO 9001:2015 certified company, Home Sunshine Pharma serves research institutions, universities, and industries in Europe, America, and Southeast Asia with their chemical products.
Jigchem Universal is a manufacturer of active pharmaceutical ingredients (APIs) and chemicals that was established in 2002 in Maharashtra, India. The company produces compounds used for a wide range of applications such as medication, industrial processing, and personal care products. Its products include inorganic solvents for surface treatment of various materials, APIs for human or veterinary use, and biocides for water treatment processes. The company serves clients in the pharmaceutical manufacturing, laboratory research, and metal fabrication sectors.
Yichang Sanxia Proudin Biopharmaceutical Co., Ltd., founded in China in 1974, is a manufacturer of Amino Acid series raw materials. The company's product portfolio includes Pharmaceutical Grade Amino Acids, Amino Acids for Special Medical Food, Amino Acids for Medium, High-Purity Pharmaceutical Intermediate Amino Acid and Food Grade Amino Acids. Their products are used in industries such as Food and Beverage, Pharmaceutical and Biotechnology, Chemical and Petrochemical, Environmental Testing and healthcare.
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
Nutra Healthcare Private Limited, established in 2012 and headquartered in Surat, India, is a manufacturer and exporter of Nutraceutical Products. The company’s product range includes protein powder, weight loss powder, pharmaceutical tablets, vitamin premix, pea protein, and more. The company is committed to quality and adheres to industry standards, boasting ISO 22000:2005 and WHO-GMP certifications. The company has a large production capacity to meet bulk demands and ensure the safe packaging of products for transportation.
Nacalai Tesque Inc., founded in 1846 and headquartered in Kyoto, Japan, is a manufacturer of research chemicals, fine chemicals, diagnostics, and the related instruments. Some of its products include cytokines, nucleic acid electrophoresis, cell dissociation reagents, and sialic acid-related products, and it also offers custom and bulk service for bulk reagents and cell culture media. The company has more than 50 domestic distributors and several worldwide, including Asia, the Middle East, Oceania, Europe, and Africa. It is ISO 9001 and ISO 9002 certified, while the Kyoto South brand and Tesque factory are ISO 14001 certified.
Xi'an Healthful Biotechnology Co., Ltd., established in 2011 and headquartered in Xian, China, is a manufacturer and supplier specializing in systematic product solutions in the nutrition and health field. The company offers a diverse and extensive product portfolio that includes plant sterols, natural vitamin E, functional oil microencapsulation, functional powder microencapsulation, and microbial fermentation. These products find crucial applications in dietary supplements, food and beverage fields, pharmaceuticals, personal care products, and animal nutrition, serving global markets.
ALPSURE LIFESCIENCES PVT. LTD., founded in Haryana, India, in 2015 is a manufacturer and distributor of Phytochemicals, Chemicals, Natural Herbal Extracts, and Organic Herbal Extracts. The company's product portfolio includes fruit Extracts Powders, Hadjod Cissus Quadrangularis Extracts, industrial chemicals, Nutraceuticals and dietary supplements and vitamin chemical powders. Their products are used in industries such as Food and Beverage, Pharmaceutical and Biotechnology, Chemical and Petrochemical, Agriculture and healthcare. The company has a global distribution network and a customer support center.
Kevy's Labs, established in 2012 with its headquarters in Hyderabad, India, is a manufacturer, supplier, and exporter of pharmaceutical intermediates. Since its, under the CEO K Veeraiah, the company has achieved substantial success and operates as a Limited Company (Ltd./Pvt.Ltd.) with an annual turnover ranging from Rs. 10 to 25 Crores. Kevy's Labs aspires to be a global figure in Bulk Drug Intermediates and Specialty Chemicals, delivering excellence in every aspect of operations.
Hexon Laboratories Pvt. Ltd., based in Nashik, Maharashtra, India, was founded in 2007 and is a manufacturer and supplier of products, oils, and acids used in the fields of chromatography, chemicals, biotechnology, and organic agriculture. The company's product portfolio includes Animal Nutrition, Essential Oils, and Amino Acids utilized in food and beverages. The company's products are made in sophisticated, cutting-edge facilities around the world in accordance with the international standards.
Founded in 1981, Central Drug House Ltd. serves the scientific community via manufacturing and marketing a library of over 9,000 products to laboratory fine chemicals and dehydrated culture media with emphasis on purity and service. Examples are acids & bases, adsorbents, disinfectants, indicator papers, oils, and solvents. CDH provides bio chemicals, research chemicals, laboratory reagents, various solvents, stains & indicators, and dehydrated culture media. CDH is ISO 9001 certified and CDHs’ products are in compliance with specifications of IP, BP, USP, and EP standards.
Founded in Mumbai, India in 2006, Otto Chemie Pvt. Ltd. is an ISO 9001:2015 & GMP certified chemical manufacturing company and distributor. Otto Chemie serves customers in many industries including agriculture and food processing, pharmaceuticals, oil & gas, cement, as well as educational and R&D industries. Product offerings include antibiotics, amino acids, vitamins, detergents, ionic liquids, materials science compounds, labware, oil, metal & ceramic science compounds and tools, oils, reagents, solvents.
National Analytical Corporation (NAC) is located in Mumbai, India. NAC was founded in 2009 as a distributor of laboratory grade chemicals used in numerous industries. NAC’s chemical offerings include biochemical & reagents such s Prunetin and 1,2-dipalmitoly-rac-glycerol, analytical grade chemicals such as chicoric acid and Vitamin E solutions, laboratory chemicals such as formic acid and nitric acid, gas chromatography chemicals such as Aalborg mass flowmeter battery kits and DEX 225, reference standard chemicals such as Palladium in HNO3, oral solid dosage forms, such as cellulosic and protect film coating systems, parenteral dosage forms, beverage & nutrition, and coating chemicals.
Foodchem was founded in 2006 in Shanghai, China. The company is ISO 9001 certified and is a producer, distributor, R&D provider, and marketer of specialty and standard food additives and ingredients to pharmaceutical, cosmetic, nutrition, and chemical industries around the world through distributors and self-managed warehouses. The company operates through four product segments: Food Ingredients, Feed Additives, Industrial Chemicals, and Active Pharmaceutical Ingredients. Certain categories include Kosher and Halal-certified products and products meeting other dietary restrictions.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | KYOWA HAKKO BIO CO.,LTD. |
11.1%
|
| 2 | JIGCHEM UNIVERSAL |
9.3%
|
| 3 | Hebei Honray Imp. & Exp. Co., Ltd. |
7.4%
|
| 4 | NutraCap Labs |
7.4%
|
| 5 | Yichang Sanxia Proudin Biopharmaceutical Co., Ltd. |
7.4%
|
| 6 | Zhejiang Shengyu Chemical Co Ltd |
5.6%
|
| 7 | Hexon Laboratories Pvt. Ltd. |
5.6%
|
| 8 | Hefei Home Sunshine Pharmaceutical Technology Co., Ltd. |
5.6%
|
| 9 | Shanghai Tianjia Biochemical Co.,Ltd |
3.7%
|
| 10 | Xi'an Healthful Biotechnology Co.,Ltd. |
3.7%
|
Derivation Method
The ranking is calculated based on the click share within the l-valine page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
China
|
7 | 38.9% |
|
India
|
6 | 33.3% |
|
Japan
|
4 | 22.2% |
|
United States of America
|
1 | 5.6% |
1 products found
1 products
ChemFine International Co., Ltd.
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Nutritional supplements. It can be used to prepare aminophenol injections and synthesize aminophenols in other essential amino acid injections. Val...
