This section provides an overview for polysorbate as well as their applications and principles. Also, please take a look at the list of 21 polysorbate manufacturers and their company rankings. Here are the top-ranked polysorbate companies as of November, 2024: 1.MedKoo Biosciences, Inc., 2.Hefei TNJ Chemical Industry Co.,Ltd., 3.Merck Millipore.
Table of Contents
Polysorbate esters, derived from the esterification of sorbitan's hydroxy groups with fatty acids, play versatile roles as nonionic surfactants in various industries, including food, cosmetics, and plastics.
As surfactants, polysorbates find applications in enhancing food flavors and cosmetics formulations, and as antistatic, antifogging, and mold release agents in the plastic industry. Their selection is crucial, given the diversity in chemical properties among the polysorbates.
Characterized by both hydrophobic and hydrophilic groups, polysorbates excel in emulsifying and dispersing, acting as a bridge between water and oil, thus facilitating various surfactant applications.
Polysorbates can be categorized into spun and twin types, with their hydrophilicity influenced by the addition of ethylene oxide (twin type) or the fatty acid composition (spun type).
The diversity of polysorbate types is largely due to the variety of fatty acids that can esterify sorbitan, ranging from saturated to unsaturated, and affecting the compound's hydrophilicity and applications.
While spun polysorbates are considered low-hazard and permissible as food additives due to their benign decomposition, the twin-type polysorbates have seen regulatory evolution, with their use in food approved since 2008.
*Including some distributors, etc.
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MedKoo Biosciences, Inc. is an American manufacturer of biochemical reagents established in 2009 and based in Morrisville, North Carolina. Specializing in small molecule drugs for laboratory use, the company offers a wide range of products including apoptosis inducers, anticancer reagents, epigenetic modulators, and various pharmaceutical related chemicals. These have applications in various fields including microbiology, stem cell research, endocrinology, and epigenetics. MedKoo Biosciences also provides R&D services to client biotechnology, biomedical, and pharmaceutical companies, as well as academic institutions.
Spectrum Chemical MFG Corp. was founded in 1971, is headquartered in New Brunswick, New Jersey, and has facilities in Gardena, California. Spectrum is a fine chemical manufacturing company with an emphasis on USP, NF, FCC, BP, EP, JP, and ACS grade products, and is ISO 9001:2015 certified. Spectrum primarily serves the analytical, biopharmaceutical, food & beverage, personal care, and pharmaceutical chemicals industries. Spectrum has 4 product segments which are chemicals, equipment, supplies, and safety.
Santa Cruz Biotechnology, Inc., established in 1991 and headquartered in Dallas, Texas, is an American manufacturer and supplier specializing in biological products for medical research. Initially providing antibodies to the research community, they expanded their offerings to include gene silencers like siRNA and shRNA (plasmid and lentiviral), targeting all known mouse and human genes. Over time, Santa Cruz Biotechnology provides over 175,000 research biochemicals under the brand ChemCruz, including protein-interacting inhibitors, substrates, and activators, tailored for studying protein functions. The company offers monoclonal primary antibodies, designed for various mammalian and non-mammalian protein targets, along with corresponding binding secondary antibodies.
Graham Chemicals, established in 1988 is a global chemical distribution firm. Situated in Illinois, USA, they offer superior specialty chemical intermediates, surfactants, and performance additives. Some of their focuses include food, flavor, and fragrance industries and industrial and institutional markets. They also provide manufacturing services such as food grade and technical blending, reactions, and milling through their extensive supplier network. With their reliable services and competitive prices, they are known as one of the preferred chemical distributors in the United States.
Hefei TNJ Chemical Industry Co., Ltd, established in 2001, is headquartered in China. The company is a chemical manufacturer and supplier of chemicals to domestic Chinese and global consumers in four primary markets: chemicals, food, pharmaceuticals, and personal care. Chemicals include fine chemicals, agrochemicals, and other chemicals. Food includes agrochemicals, vitamins, amino acids, and food ingredients. Pharmaceuticals include specific chemicals such as Povidone iodine, Clotrimazole crystalline, and Lincomycin. The company also features a CAS databank for CAS-registered chemical compounds.
Loba Chemie Pvt. Ltd. is a Mumbai-based manufacturer and supplier of laboratory and fine chemicals, catering to industries such as pharmaceuticals, food, research, hospitals, and universities since its establishment in 1975. Their product range includes pH indicators, biological stains, HPLC solvents, high purity acids, and tetrazolium salts and derivatives. These products serve various applications like pH testing, cell and tissue staining, chemical separation, and pharmaceutical manufacturing. The company has several certifications, such as ISO/IEC 17025:2017 and ISO 9001:2015.
Toronto Research Chemicals Inc., founded in 1982 and based in Toronto, Canada, is a manufacturer of biochemicals and is a subsidiary of LGC Standards. The ISO 9001-certified company has an extensive catalog of over 350,000 products, including metabolites, impurities, and natural products APIs, which are used in several applications like environmental analysis, forensic science, and medicinal R&D. The company supports the scientific community across more than 120 countries and has 19 production laboratories. In 2019, it was bought by LGC, which provides components to customers in the pharmaceutical, clinical diagnostics, and food markets, among others.
Alfa Chemistry, founded in the year 2015 is based in New York, USA as a biotechnology company and manufacturer of graphene materials. Their product portfolio includes graphene oxide, CVD graphene film, graphene modification services, graphene series, graphene-like material, carbon nanomaterials, quantum dots, upcoming nanoparticles, and graphene transfer services. The company also provides services in custom manufacturing, and graphene analysis with quality assurance. The products are used in various industries which include energy, digital electronics, environment, textile, coating, and biomedical science.
PCC Group, founded in, Brzeg Dolny, Poland, in 1993 is a manufacturer of industrial chemicals. The company's product portfolio includes personal care ingredients, paints and coatings, adhesives and sealants, polyester polyols, and green chemistry Their products are used in industries such as Food and Beverage, Pharmaceutical and Biotechnology, Chemical and Petrochemical, Environmental Testing and healthcare. The company has 74 entities operating in 39 locations across 17 countries and offers custom packaging, warehousing, and global distribution services.
TCI America (TCI) was founded in 1946 and is a worldwide manufacturer of specialty organic chemicals. The company produces organic laboratory chemicals as well as pharmaceutical, cosmetic, and functional materials. TCI’s product segments include Chemistry, Life Science, Materials Science, Analytical Chemistry, and Custom & Bulk. For materials science, the company manufactures battery materials, nanocarbon materials, and magnetic materials. For life sciences, the company produces antibodies, reagents, and chemicals for cancer research. The company produces HLC, NMR, various chemicals, and resins and media for analytical chemistry.
Venus Ethoxyethers Pvt. Ltd. is a manufacturer of manufacturer of surfactants and speciality chemicals. It is headquartered in Goa, India, and was established in 1996. The company produces a range of surface-active agents, including nonionic, anionic, and cationic surfactants. Some of its popular products are ethoxylated alcohols, ethoxylated amines, and ethoxylated fatty acids. Venus Ethoxyethers Pvt. Ltd. also provides technical support and training services. Its products are used in many industries, including personal care, cosmetics, and pharmaceuticals. The company is ISO-9001-2015, ISO-14001-2015 and ISO-45001-2018 certified, and is run under an SOP standard.
ITW Reagents, S.R.L. is based in Monza and Brianza, Italy, and is a diversified manufacturer of industrial products that was founded in 1980 as Nova Chimica before being acquired in 2010 by Illinois Tool Works Inc. (ITW), and rebranding in 2022. The company specializes in reagents and solutions used for analytical chemistry as well as life sciences. Its products include sodium hydroxide pellets, glycerol anhydrous for molecular biology, and crystalline lactic acid lithium salts. The company chiefly serves clients in the food and beverage, pharmaceutical, and biotechnology sectors.
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
Alfa Aesar is based in Lancashire, United Kingdom. Alfa Aesar is part of Thermo Fisher Scientific, is a manufacturer and supplier of chemicals, metals, and life science products for research and development. Alfa Aesar’s product lines include chemicals, life science, materials & metals, catalysts, and analytical & lab ware. Chemical offerings include inorganic compounds, organic compounds, organometallic, and solvents. Life sciences include biotechnology products, cellular & molecular biology, genomics, and immunology. Materials & metal include alloys, carbon, etchants, and more. Catalysts include ferrocenes, fuel cell products, and precious metals & catalysts. Alfa Aesar also offers custom manufacturing options.
Merck Millipore, founded in 1954 and headquartered in Darmstadt, Germany, is a manufacturer, distributor, and supplier of life science products and services. Their diverse range of products finds applications in research, development, and manufacturing of biotechnological and pharmaceutical drug therapies. Some of their offerings include filters for removing contaminants from liquids and gases, chromatography columns for separating and analyzing complex mixtures, reagents used in various laboratory assays, antibodies for detecting and quantifying specific molecules, and cell culture media for growing and maintaining cells in culture. Their products and services are utilized significantly in the advancement of life sciences and drug development.
Sisco Research Laboratories Pvt. Ltd. was established in 1975 and is headquartered in Mumbai, Maharashtra, India. The company manufactures highly complex reagents and biochemicals for public and private customers across industries with over 5000 products in different grades and packing sizes across product segments. The company’s 6 product categories are General Laboratory Chemicals & Solvents, Biochemicals & Specialty Fine Chemicals, Animal Cell Culture, Nanotechnology Products, Dehydrated Culture Media & Media Kits, and Biolit™ range of DNA and Protein tools.
Glentham Life Sciences is based in Corsham, United Kingdom. Glentham Life Sciences is a leading supplier of fine chemicals, raw materials, reagents, and life science products. Glenthem also offers a number of services including custom packaging, call-off orders, and safety documentation. Glentham’s product offerings include chemicals such as amino acids, antibiotics, APIs, biochemicals, buffers, carbohydrates, chitin, chitosan, detergents, dyes, stains, enzymes, inorganic, peptide reagents, phytochemical, raw materials, solvents, steroids, and vitamins among others.
Ataman Kimya A. S (Ataman Chemicals LLC), founded in 1940 and based in Istanbul, Turkey, is a supplier of pharmaceuticals and chemical raw materials. Ataman Kimya A. S serves industries including agriculture, cosmetics, food additive, petroleum, among others with products such as disinfectants, cosmetics, metal and mining chemicals, textile and leather chemicals, paints, as well as industrial and pharmaceutical chemicals. The company holds the sales and marketing rights of Nordic Chemical Laboratories and is known for the enviromental care it provides.
HAZMAT Resource, Inc., located in Irvine, California, USA, is a distributor of hazardous materials response equipment and materials. They specialize in personal protective equipment (PPE), testing devices, and technical reference materials for hazardous materials (hazmat) response. Their product range includes PPE such as suits, gloves, boots, and respirators to safeguard hazmat responders from dangerous substances. They offer various testing devices like meters, detectors, and kits for precise identification and measurement of hazardous materials. Additionally, the company provides technical reference materials like books, manuals, and software, equipping responders with essential knowledge on hazardous material properties and safe handling procedures.
Ranking as of November 2024
Derivation MethodRank | Company | Click Share |
---|---|---|
1 | MedKoo Biosciences, Inc. |
14.3%
|
2 | Hefei TNJ Chemical Industry Co.,Ltd. |
12.1%
|
3 | Merck Millipore |
8.8%
|
4 | Croda Pharma |
7.7%
|
5 | SRL |
7.7%
|
6 | Alfa Chemistry |
7.7%
|
7 | Venus Ethoxyethers Pvt. Ltd |
4.4%
|
8 | PCC Group |
4.4%
|
9 | ITW Reagents, S.R.L. |
3.3%
|
10 | LobaChemie Pct.Ltd. |
3.3%
|
Derivation Method
The ranking is calculated based on the click share within the polysorbate page as of November 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
Country | Number of Companies | Share (%) |
---|---|---|
United States of America | 4 | 26.7% |
India | 3 | 20.0% |
United Kingdom | 2 | 13.3% |
China | 1 | 6.7% |
Canada | 1 | 6.7% |
United States | 1 | 6.7% |
Poland | 1 | 6.7% |
Japan | 1 | 6.7% |
Turkey | 1 | 6.7% |