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This section provides an overview for sulfamic acid as well as their applications and principles. Also, please take a look at the list of 12 sulfamic acid manufacturers and their company rankings. Here are the top-ranked sulfamic acid companies as of December, 2024: 1.ChemCeed LLC, 2.The Science Co., 3.Vivochem.
Table of Contents
Figure 1. Basic Information on Sulfamic Acid
Sulfamic acid, known also as amidosulfuric acid, is a water-soluble chemical formed by substituting the hydroxyl group in sulfuric acid with an amino group. This white solid decomposes at 205°C and is insoluble in ethanol, not hygroscopic, facilitating the production of a pure form. Its synthesis involves urea and fuming sulfuric acid.
Reacting with nitrous acid yields nitrogen gas, and nitric acid, acts as a reducing agent, producing nitrous oxide.
As a precursor to the artificial sweeteners Cyclamate and acesulfame potassium, sulfamic acid finds extensive use. It also reacts with 2-ethyl hexanol to form 2-ethylhexyl sulfate, used in cotton silketing and as a standard in acid-base titrations for determining sodium hydroxide concentrations. Moreover, it serves as a cleaning agent and rust remover, offering an odorless alternative to hydrochloric acid-based cleaners.
In aqueous solutions, sulfamic acid exhibits strong acidity (Ka = 1.01×10−1), dissolving metal salts without corroding metals. It hydrolyzes to ammonium hydrogen sulfate above 80°C and releases ammonia when heated in water.
Figure 2. Structure of Sulfamic Acid
The chemical structure of sulfamic acid (H3NSO3), featuring a molar mass of 97.10 g/mol and a density of 2.15 g/cm3, includes a tautomeric zwitterionic form, as determined by neutron diffraction studies.
It acts as a scavenger of hypochlorite ions in various chemical oxidations and forms sulfate esters when reacted with alcohols under mild conditions, facilitated by urea as a catalyst.
Figure 3. Synthesis of Cyclo from Sulfamic Acid
The reaction between sulfamic acid and cyclohexylamine, in the presence of sodium hydroxide, produces Cyclo, a sodium cyclamate sweetener, demonstrating a sweetness significantly greater than sugar but with a bitter aftertaste at high concentrations.
*Including some distributors, etc.
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ChemCeed, founded in 2009 and headquartered in Chippewa Falls, Wisconsin, is a worldwide chemical supplier that is ISO 9001 certified. It provides chemicals like base oils, corrosion inhibitors, and specialty esters used in several industries, including construction, paper manufacturing, and water treatment. It also provides a broad selection of support services, including labeling, repackaging, and logistical support. The company stocks its products in several locations around the United States, including Chicago (IL), Philadelphia (PA, and Piscataway (NJ). In 2016, it received WBE certification and was NACD verified in 2023.
Connection Chemical, LP, founded in 2010 with headquarters in the USA, is a distributor and supplier of industrial chemicals and fine ingredients. The company's products include inorganic chemicals such as acids, carbonates, chlorides, and liquid caustic soda, as well as organic liquids, including nonylphenol ethoxylates, used in various industries that include the HI&I, detergents, personal care, cosmetics, and lubricants markets. Some examples include serving the agriculture industry with nutrients and fertilizers, the energy industry with component fluids and fracking additives, and the food processing industry with preservatives and acidulants. Connection Chemical, LP, is a member of the NACD.
Parchem was founded in 1999 and headquartered in Rochelle, New York. Parchem is a distributor of industrial chemicals. Parchem serves nutritional, personal care, pharmaceutical, and specialty chemical industries. Parchem offerings include coatings, adhesives, elastomers, industrial products, petrochemicals, oleochemicals, plastics, rubber, nutritional supplements, cosmetics, consumer products, catalysts, metallic salts, rare earths, flavors & fragrances, industrial & institutional, textiles, other food-related chemicals, dyes, finishes, chemicals for aerospace, oil gas drilling chemicals, electronics, and pharmaceuticals.
Wego Chemical Group was founded in 1978 and headquartered in Great Neck, New York. WEGO is a full-service supplier and distributor of chemicals, minerals, and other raw materials to clients around the world. Markets and segments include agriculture & animal care, chemical & material manufacturing, construction & building materials, electronics, food & beverage, “household, industrial & institutional”, mining, oil & gas, personal care & pharmaceutical, paper & packaging, surface treatment, textiles, and water treatment.
Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
Junsei Chemical Co. Ltd., established in 1948 and headquartered in Tokyo, Japan, is a manufacturer of chemical reagents and chemical products, including commissioned synthesis of chemical products. Some of the products it makes include Sodium chloride solution, concentrated glycerin, calcium chloride, ascorbic acid, and nitric acid. The chemical products have a wide range of applications and can be used in pathological examination, as food additives, for analysis, and in the pharmaceutical industry. All its plants, including its research institute, are ISO4001 and ISO9001 certified, while its Saitama and Ibaraki plants are equipped with buildings that comply with GMP.
Kishida Chemical Co. Ltd., established in 1924 and headquartered in Osaka, Japan, is a manufacturer of reagents and high-purity chemicals and also does drug discovery support activities. Its product portfolio includes fine chemicals, research chemicals, ionic liquid, organic micro-analytical reagents, and chemical reagents for analysis. The products support several industries, including reagent business, battery material, drug discovery, and life science. The company is ISO 14001 certified and supplies several companies worldwide, including Meterion Advanced Chemicals Inc., Acros Organics, ChemBridge Corporation, Decon Laboratories, and InerBioScreen Ltd.
ViVoChem, established in 2006 and based in Almelo, the Netherlands, is a chemical manufacturer and supplier operating under BÜFa Gmbh & Co. Kg (BÜFa Group). The company's offerings include chemical raw materials supplied to the adhesive, agricultural, food, personal care, and paint industries. It also offers solutions related to chemical raw material handling, storage, and distribution. The company’s drumming facilities, complete with intermediate bulk containers (IBCs), facilitate chemical packaging. It also operate a warehouse facility, complying with Accord Dangereux Routier (ADR) regulations for hazardous substances. Moreover, the company conducts chemical distribution through truck cargos and provides assistance in chemical export processes.
Merck, started in 1668 and based in Darmstadt, Germany, is a supplier of solutions and services for research, development, and manufacture of pharmaceutical and biotechnological drug therapies. The company serves the life science industry and has a broad portfolio of 300,000 products, including biopharmaceutical manufacturing, industrial microbiology, reagent, life science research, and water purification products. It is available in 66 countries, brings together six brands, and has several ISO certifications, including ISO 13485, ISO 14001, ISO 13485, and ISO 50001.
Nacalai Tesque Inc., founded in 1846 and headquartered in Kyoto, Japan, is a manufacturer of research chemicals, fine chemicals, diagnostics, and the related instruments. Some of its products include cytokines, nucleic acid electrophoresis, cell dissociation reagents, and sialic acid-related products, and it also offers custom and bulk service for bulk reagents and cell culture media. The company has more than 50 domestic distributors and several worldwide, including Asia, the Middle East, Oceania, Europe, and Africa. It is ISO 9001 and ISO 9002 certified, while the Kyoto South brand and Tesque factory are ISO 14001 certified.
The Science Co. is a manufacturer and supplier of scientific instruments, established in 2003, located in the United States The company specializes in designing and producing a range of advanced scientific instruments and equipment for laboratories, research facilities, and educational institutions. The product offerings include analytical instruments, laboratory equipment, and scientific consumables, all designed to facilitate precise research and experimentation. The products adhere to stringent quality standards and offer cutting-edge technology to meet the evolving needs of researchers and scientists.
Glentham Life Sciences is based in Corsham, United Kingdom. Glentham Life Sciences is a leading supplier of fine chemicals, raw materials, reagents, and life science products. Glenthem also offers a number of services including custom packaging, call-off orders, and safety documentation. Glentham’s product offerings include chemicals such as amino acids, antibiotics, APIs, biochemicals, buffers, carbohydrates, chitin, chitosan, detergents, dyes, stains, enzymes, inorganic, peptide reagents, phytochemical, raw materials, solvents, steroids, and vitamins among others.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | ChemCeed LLC |
17.0%
|
| 2 | The Science Co. |
9.4%
|
| 3 | Vivochem |
9.4%
|
| 4 | Merck |
9.4%
|
| 5 | Glentham Life Sciences Limited |
7.5%
|
| 6 | Connection Chemical |
7.5%
|
| 7 | Wego Chemical Group Inc |
7.5%
|
| 8 | Junsei Chemical Co.,Ltd. |
7.5%
|
| 9 | Kishida Chemical Co.,Ltd. |
7.5%
|
| 10 | KANTO CHEMICAL CO.,INC. |
7.5%
|
Derivation Method
The ranking is calculated based on the click share within the sulfamic acid page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
United States of America
|
4 | 40.0% |
|
Japan
|
4 | 40.0% |
|
Netherlands
|
1 | 10.0% |
|
United Kingdom
|
1 | 10.0% |
