This section provides an overview for diphenylamine as well as their applications and principles. Also, please take a look at the list of 17 diphenylamine manufacturers and their company rankings. Here are the top-ranked diphenylamine companies as of November, 2024: 1.Cayman Chemical Company, 2.Corey Organics, 3.Zhengzhou Meiya Chemical Products Co.,Ltd..
Table of Contents
Diphenylamine is an organic compound with the structural formula (C6H5)2NH. It is a secondary amine composed of two phenyl groups and is classified as an aromatic amine. Also known as N-phenylbenzeneamine or DPA, its CAS registration number is 122-39-4.
Diphenylamine serves various purposes, including as a reagent for detecting nitrates, a raw material for organic syntheses, and a stabilizer for explosives and chlorinated solvents. It's notably used in the nitrate reaction for detecting nitrates and in DNA extraction.
As a synthetic raw material, it's employed in pharmaceuticals, dyes, organic rubber chemicals, and phenothiazines, serving as a polymerization inhibitor. It's also used in the synthesis of anti-aging agents and various dyes.
Diphenylamine, with a molecular formula C12H11N and molecular weight 169.23, is a white or yellow crystalline solid. It has a melting point of 53°C and a boiling point of 302°C. While insoluble in water, it readily dissolves in various organic solvents such as ethanol, acetone, benzene, and pyridine.
Diphenylamine is sold as both an R&D reagent and an industrial chemical. Reagent-grade products come in various capacities and require refrigerated storage, while industrial-grade products are supplied in larger units for specific applications such as stabilizing dye intermediates and nitrocellulose.
Diphenylamine is synthesized by pressurizing and heating aniline hydrochloride and aniline, or by the deamination reaction of aniline in the presence of an oxide catalyst.
Diphenylamine undergoes color reactions such as the Runge test, turning dark blue in the presence of nitrate or nitrite ions, and the Dish reaction, producing a blue color with 2-deoxypentose. These reactions are used in detecting ions and DNA quantification, respectively.
It reacts with strong acids to form salts and readily undergoes cyclization reactions, producing compounds like phenothiazine and carbazole.
Diphenylamine is classified as hazardous due to potential serious effects on various systems and possible carcinogenicity. It should be handled with appropriate protective measures and in compliance with safety regulations.
*Including some distributors, etc.
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Cayman Chemical Company is a manufacturer of life science research products founded in 1979 in Ann Arbor, Michigan, USA. They offer a diverse array of analytical standards, reagents, and other products for research in cancer, oxidative injury, epigenetics, neuroscience, inflammation, as well as metabolism, and other areas. The company supplies small molecules, biochemicals, assay kits, antibodies, and proteins to research scientists across academic, biotechnology, and pharmaceutical institutions. Cayman Chemical Company holds dual accreditations to ISO/IEC 17025:2017 and ISO 17034:2016 by ANAB Accreditation Services.
Emco Dyestuff Pvt. Ltd., established in 1980 with headquarters in India, is a manufacturer of intermediates, industrial chemicals, solvents, and specialty chemicals used in various industries, including agrochemicals, electronics, and pharmaceuticals. Some of the company's products are ethylhexanoic acid, sodium sulfate anhydrous, Toluene Diisocyanate, and monoethylamine. The company is partnered with a number of companies, including OpenSpace Services, a manufacturer of specialty chemicals; Emco Engineering, a manufacturer of pharmaceutical machines; and Kosha Chemtech Pvt. Ltd., a software and IT support company providing simplified outsourcing solutions.
Kishida Chemical Co. Ltd., established in 1924 and headquartered in Osaka, Japan, is a manufacturer of reagents and high-purity chemicals and also does drug discovery support activities. Its product portfolio includes fine chemicals, research chemicals, ionic liquid, organic micro-analytical reagents, and chemical reagents for analysis. The products support several industries, including reagent business, battery material, drug discovery, and life science. The company is ISO 14001 certified and supplies several companies worldwide, including Meterion Advanced Chemicals Inc., Acros Organics, ChemBridge Corporation, Decon Laboratories, and InerBioScreen Ltd.
TCI America (TCI) was founded in 1946 and is a worldwide manufacturer of specialty organic chemicals. The company produces organic laboratory chemicals as well as pharmaceutical, cosmetic, and functional materials. TCI’s product segments include Chemistry, Life Science, Materials Science, Analytical Chemistry, and Custom & Bulk. For materials science, the company manufactures battery materials, nanocarbon materials, and magnetic materials. For life sciences, the company produces antibodies, reagents, and chemicals for cancer research. The company produces HLC, NMR, various chemicals, and resins and media for analytical chemistry.
Loba Chemie Pvt. Ltd. is a Mumbai-based manufacturer and supplier of laboratory and fine chemicals, catering to industries such as pharmaceuticals, food, research, hospitals, and universities since its establishment in 1975. Their product range includes pH indicators, biological stains, HPLC solvents, high purity acids, and tetrazolium salts and derivatives. These products serve various applications like pH testing, cell and tissue staining, chemical separation, and pharmaceutical manufacturing. The company has several certifications, such as ISO/IEC 17025:2017 and ISO 9001:2015.
Seiko Chemical Co., Ltd., established in 1948 in Tokyo, Japan, is a manufacturer of fine chemicals and plastic processing chemicals. Its product range includes polymerization inhibitors, intermediates for dyes and pigments, and photopolymerization initiators. These chemicals play a crucial role in stabilizing raw materials for synthetic resins, such as superabsorbent polymers used in paper diapers and synthetic fibers. Additionally, the company offers other chemicals, such as epoxy resin catalytic agents and corrosion inhibitors.
Corey Organics was founded in 1994, and its headquarters is in Telangana, India, as a manufacturer of Active Pharmaceutical Ingredients (APIs), registered Pharma Intermediates, Fine Chemicals and Pyridine Derivatives for catering to the domestic as well as international market. Corey Organics has robust manufacturing facilities, and the company's management is commended to individuals with extensive experience and competence in manufacturing bulk medicines and the corresponding intermediates. This tactical approach ensures the delivery of superior products and fosters strong business relationships with clients across the globe.
LANXESS AG, established in 2004 and headquartered in Cologne, Germany, is a specialty chemical manufacturer. The company emerged from a restructuring process within Bayer AG, a German pharmaceutical and biotechnology company. As part of this transformation, certain chemical and polymer business units were spun off to create LANXESS as an independent entity. Under various brand names like Bayferrox and Colortherm for synthetic inorganic pigments, Lewatit for ion exchange resins, Bayoxide for iron oxide adsorbers, and Rely+On for disinfectant solutions, LANXESS offers a diverse range of products. These serve various industries, including agriculture, automotive, biosecurity, construction, microbial control, and mining.
Merck, started in 1668 and based in Darmstadt, Germany, is a supplier of solutions and services for research, development, and manufacture of pharmaceutical and biotechnological drug therapies. The company serves the life science industry and has a broad portfolio of 300,000 products, including biopharmaceutical manufacturing, industrial microbiology, reagent, life science research, and water purification products. It is available in 66 countries, brings together six brands, and has several ISO certifications, including ISO 13485, ISO 14001, ISO 13485, and ISO 50001.
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
Sarex Chemicals, a company founded in 1952, operates as a manufacturer and supplier based in Mumbai, India. The company specializes in chemical solutions has a diverse product range encompasses specialty chemicals, textile auxiliaries, and fine chemicals. Integral to various industries, including textiles, pharmaceuticals, and agrochemicals, Sarex's offerings drive revolution and efficiency. Its legacy of quality and proficiency has positioned it as a crucial partner in multiple sectors, illustrating its pivotal role in India's chemical landscape.
Carl Roth GmbH + Co. KG, established in 1879 and headquartered in Karlsruhe, Germany, is a manufacturer, distributor, and supplier of laboratory equipment, life science products, and chemicals. Their extensive product range encompasses analytical instruments, biological safety cabinets, heating mantles, pH meters, centrifuges, thermometers, and various chemicals. Their products support and facilitate laboratory research, analysis, and experimentation across various industries such as pharmaceutical, chemical, and environmental sectors. The company is certified according to DIN EN ISO 9001:2015 and DIN EN ISO 14001:2015.
Sisco Research Laboratories Pvt. Ltd. was established in 1975 and is headquartered in Mumbai, Maharashtra, India. The company manufactures highly complex reagents and biochemicals for public and private customers across industries with over 5000 products in different grades and packing sizes across product segments. The company’s 6 product categories are General Laboratory Chemicals & Solvents, Biochemicals & Specialty Fine Chemicals, Animal Cell Culture, Nanotechnology Products, Dehydrated Culture Media & Media Kits, and Biolit™ range of DNA and Protein tools.
Zhengzhou Meiya Chemical Products Co., LTD was founded in 2005 in Henan, China, and is headquartered in Zhengzhou, China. The company is a distributor and exporter of chemicals from China to Europe, Asia, and the Americas. The ISO 9001-certified company specializes in VOC-exempt solvents, paints and coatings, adhesives, PU, and resin for industries such as agriculture, pharmaceuticals, feed, water treatment, and oil field chemicals. The company’s product categories include plant extracts, cosmetics, PU, and resin.
Anant Pharmaceuticals Pvt. Ltd., established in 2005, is a supplier of pharmaceutical impurity reference samples and custom synthesis and analytical services, based in India. The company delivers novel solutions to research and development teams. Their organic synthesis labs are equipped with modern equipment, designed with energy saving concept. Over the years, they have developed into a one-stop service provider for bespoke chemical synthesis and analytical services for a wide range of industries in India and abroad.
Glentham Life Sciences is based in Corsham, United Kingdom. Glentham Life Sciences is a leading supplier of fine chemicals, raw materials, reagents, and life science products. Glenthem also offers a number of services including custom packaging, call-off orders, and safety documentation. Glentham’s product offerings include chemicals such as amino acids, antibiotics, APIs, biochemicals, buffers, carbohydrates, chitin, chitosan, detergents, dyes, stains, enzymes, inorganic, peptide reagents, phytochemical, raw materials, solvents, steroids, and vitamins among others.
Henan GP Chemicals Co., Ltd., established in 2014 with its head office in Zhengzhou and a secondary office in Henan, China, is a distributor of chemical products from China. The company offers over 1,000 products, including chlorinated paraffin, isobutyl isobutyrate, and trioctyl trimellitate. Henan GP Chemicals Co., Ltd.'s main products are used in solvents, plastics and rubber, adhesives, pharmaceuticals, and agriculture. The company also provides custom services that include business-to-business distribution solutions for industrial and specialty chemicals around the world.
Ranking as of November 2024
Derivation MethodRank | Company | Click Share |
---|---|---|
1 | Cayman Chemical Company |
16.7%
|
2 | Corey Organics |
9.1%
|
3 | Zhengzhou Meiya Chemical Products Co.,Ltd. |
9.1%
|
4 | Tokyo Chemical Industry Co., Ltd. |
9.1%
|
5 | LobaChemie Pct.Ltd. |
7.6%
|
6 | EMCO Dyestuff PVT. LTD. |
7.6%
|
7 | LANXESS |
7.6%
|
8 | Seiko Chemical Co.,Ltd. |
7.6%
|
9 | Kishida Chemical Co.,Ltd. |
7.6%
|
10 | Sarex Chemicals |
6.1%
|
Derivation Method
The ranking is calculated based on the click share within the diphenylamine page as of November 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
Country | Number of Companies | Share (%) |
---|---|---|
India | 5 | 41.7% |
Japan | 3 | 25.0% |
United States of America | 1 | 8.3% |
Germany | 1 | 8.3% |
China | 1 | 8.3% |
United Kingdom | 1 | 8.3% |