16 Ethylene Diamine Manufacturers in 2024
This section provides an overview for ethylene diamine as well as their applications and principles. Also, please take a look at the list of 16 ethylene diamine manufacturers and their company rankings. Here are the top-ranked ethylene diamine companies as of November, 2024: 1.Oakwood Products, Inc, 2.KANTO CHEMICAL CO.,INC., 3.GFS Chemicals, Inc..
Table of Contents
What Is Ethylenediamine?
Ethylenediamine is a type of primary diamine, a clear liquid at room temperature with an ammonia odor. It is also known as 1,2-diaminoethane, 1,2-ethanediamine, and dimethylenediamine.
It is mainly used as a raw material for making other chemicals.
Uses of Ethylenediamine
Ethylenediamine is used as a synthetic raw material to make new chemicals because of its high reactivity with many compounds.
Examples in industrial fields include synthetic waxes, herbicides, surfactants, emulsifiers, wetting agents, dispersants, corrosion inhibitors, detergents, and textile surface treatments.
Examples in the medical field include drug synthesis as chemical stabilizers, such as antihistamines, and a wide range of applications, such as allergic epithelial patch testing to aid in the diagnosis of allergic dermatitis.
In the agrochemical field, it is also used in fungicides, insecticides, and herbicides.
Other applications include chelating agents, coatings, adhesives, ion exchange resin raw materials, and rubber chemicals.
Properties of Ethylenediamine
The chemical formula of ethylenediamine is NH2CH2CH2NH2, with one hydrogen atom attached to each of the two carbons of ethylene being replaced by an amine group. It has a molecular weight of 60.11, a density of 0.9 g/cc, a melting point of 8.5°C, a boiling point of 117°C, and is freely miscible with water and alcohols but slightly soluble in ether.
It is a strong base and will corrode attached tissues. When heated, it produces toxic fumes of nitrogen oxides and ammonia, so it should be handled with care.
Ethylenediamine has an unpleasant ammonia odor and can cause pain and irritation to the eyes, nose, throat, and respiratory system, and in rare cases can be life threatening.
In case of contact with eyes or skin, it is important to flush with plenty of water, seek medical attention, and move to fresh air if concentrated vapors are inhaled.
Other Information on Ethylenediamine
1. How Ethylenediamine Is Produced
Ethylenediamine is produced by the reaction of ethylene dichloride with ammonia or ammonia water. These raw materials are mixed and heated under pressure at 110°C to react.
ClCH2CH2Cl + 2NH3 / NH2H2CH2NH2 + 2HCl
The product obtained from the reaction is sent to a distillation column. There, unreacted ethylene dichloride is separated and returned to the reaction tank. In the distillation column, 40% caustic soda is shaken to neutralize the generated amine hydrochloride and ammonia chloride, and the excess ammonia that is released is returned to the reaction column for reuse.
Ethylenediamine and brine recovered from the bottom of the distillation column are sent to a separation tank, where the brine is separated from the ethylenediamine. It is purified in the rectifying column at atmospheric pressure and at 150~180℃. The residues are ethylenediamine and polyamine with boiling points of 200°C or higher. The ratio of ethylenediamine to polyamine above triamine is 2:1.
2. Polymers of Ethylenediamine
Like ethyleneglycol, ethylenediamine exists in polymers (polyethyleneamines) such as dimers and trimers. These are also produced in the manufacturing process of ethylenediamine and are separated in the distillation process. They are represented by the general formula NH2-(CH2-CH2NH)n-H and include diethylenetriamine, triethylenetetetramine, tetraethylenepentamine, and pentaethylenehexamine.
List of 16 Ethylene Diamine Manufacturers
*Including some distributors, etc.
Sort by Features
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- Company Size: largest first
- Year Founded: oldest first
- Year Founded: earliest first
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- United States of America
- Australia
- Japan
- Netherlands
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Oakwood Products, Inc
Ethylene Diamine
Manufacturer Overview
Oakwood Chemical is based in Estill, South Carolina. The company is a producer of a wide range of organics with particular emphasis on fluorine and sulfur compounds. The company also offers custom synthesis services and bulk quantities upon request. The company has independent operations and operations in collaboration with the University of South Carolina. The company’s suppliers include ChemCollect, Chess, KISHIDA CHEMICAL Co., Ltd., and Tetramer. The company’s featured products include boronic acids and esters, peptide coupling, fluorinated amines, and reagents for synthesis.
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Biotium
Ethylene Diamine
Company Overview
Biotium was founded in 2001 and is located in San Francisco, U.S.A., and is a manufacturer and supplier of life science reagents for various medical applications. The company provides DNA-binding dyes, antibody & protein labeling kits, fluorescent proteins, nucleotides, and, nucleic acid gel stains for life science-related applications. The company specializes in microbiology, neuroscience, and cancer research as well as developed patented technologies including GelRed dyes, CF Dyes, NucView Caspase-3 Substrates, EvaGreen Dyes, and TrueBlack Background Reducers for the medical science sector.
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Thermo Fisher Scientific Inc.
Ethylene Diamine
Company Overview
Thermo Fisher Scientific Inc., founded in 1956 and headquartered in Waltham, Massachusetts, is a manufacturer and supplier of life science solutions, analytical instruments, specialty diagnostics, laboratory products, and biopharma services. Through its brand names, including Invitrogen, Fisher Scientific, Patheon, Applied Biosystems, and Gibco, among others, the company provides a wide range of products, which include chromatography systems, thermal cyclers, automated cell counters, fermenters, and DNA polymerases. The company’s annual revenue is over 40 billion USD, and it serves several fields, including customers working in clinical diagnostic labs, research institutions, hospitals, government agencies, and pharmaceutical/biotech companies.
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KANTO CHEMICAL CO.,INC.
Ethylenediamine, anhydrous
Manufacturer Overview
Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
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Junsei Chemical Co.,Ltd.
Ethylene Diamine
Manufacturer Overview
Junsei Chemical Co. Ltd., established in 1948 and headquartered in Tokyo, Japan, is a manufacturer of chemical reagents and chemical products, including commissioned synthesis of chemical products. Some of the products it makes include Sodium chloride solution, concentrated glycerin, calcium chloride, ascorbic acid, and nitric acid. The chemical products have a wide range of applications and can be used in pathological examination, as food additives, for analysis, and in the pharmaceutical industry. All its plants, including its research institute, are ISO4001 and ISO9001 certified, while its Saitama and Ibaraki plants are equipped with buildings that comply with GMP.
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Kishida Chemical Co.,Ltd.
Ethylenediamine
Manufacturer Overview
Kishida Chemical Co. Ltd., established in 1924 and headquartered in Osaka, Japan, is a manufacturer of reagents and high-purity chemicals and also does drug discovery support activities. Its product portfolio includes fine chemicals, research chemicals, ionic liquid, organic micro-analytical reagents, and chemical reagents for analysis. The products support several industries, including reagent business, battery material, drug discovery, and life science. The company is ISO 14001 certified and supplies several companies worldwide, including Meterion Advanced Chemicals Inc., Acros Organics, ChemBridge Corporation, Decon Laboratories, and InerBioScreen Ltd.
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Nouryon
Ethylene Diamine
Manufacturer Overview
Nouryon has a history dating back to 1646 Sweden but was officially formed in 2018 after gaining independence from AkzoNobel. The company is a manufacturer of everyday consumer products including personal care and cleaning goods, as well as products for the agricultural, pharmaceutical, and building industries. The company’s brands include Dissolvine, Witbreak, Butanox, and Ferrazone. These brands manufacture products across five product segments: Bleaching and Oxidizing Chemicals and Technologies, Specialty Polymers, Surfactants and Chelating Agents, Polymer Production and Processing Chemicals, and Specialty Chemicals and Intermediates.
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Sargent Welch
Ethylene Diamine
Manufacturer Overview
Sargent Welch, established in 1968 in Chicago, USA, is a manufacturer of science education equipment and laboratory products. The company manufactures a broad range of products, including laboratory glassware, chemicals, scientific equipment, and educational resources. It maintains ISO 9001 quality certifications, and the features of its products include fostering engaging and effective science education, supporting laboratory research and experiments, and facilitating forensic investigations. These products find applications in educational institutions, research laboratories, and forensic facilities worldwide.
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GFS Chemicals, Inc.
Ethylene Diamine
Manufacturer Overview
GFS Chemicals was founded in 1928 and is based in Columbus, Ohio. GFS Chemicals is an ISO 9001:2015 certified manufacturer as well as a supplier of specialty and fine chemicals, serving customers worldwide. GFS serves an array of industries including pharmaceutical, electronics, energy, fragrances, agrichemical, and specialty polymers. GFS Chemicals supplies over 8,600 chemicals in the United States, available in both small and large quantities. GFS Chemicals also offers Karl Fischer reagents, PPT/PPB trace analysis grade acids, turbidity standards, and other high-quality materials.
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MilliporeSigma
Ethylene Diamine
Manufacturer Overview
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
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nacalai
Ethylenediamine, Anhydrous
Company Overview
Nacalai Tesque Inc., founded in 1846 and headquartered in Kyoto, Japan, is a manufacturer of research chemicals, fine chemicals, diagnostics, and the related instruments. Some of its products include cytokines, nucleic acid electrophoresis, cell dissociation reagents, and sialic acid-related products, and it also offers custom and bulk service for bulk reagents and cell culture media. The company has more than 50 domestic distributors and several worldwide, including Asia, the Middle East, Oceania, Europe, and Africa. It is ISO 9001 and ISO 9002 certified, while the Kyoto South brand and Tesque factory are ISO 14001 certified.
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TOMOE Engineering Co., Ltd.
Chemical products
Company Overview
Tomoe Engineering Co., Ltd., established in 1941 and located in Tokyo, Japan, is a manufacturer of decanter type centrifugal separators. The company offers a range of products, including gravity belt thickeners, HED-type dewatering centrifuges, disc-type centrifuges, rotary snails, and ASM tubular centrifuges, which cater to pharmaceuticals, food, chemistry, ships, electric power, and water treatment. The products are used in sludge dewatering, oil-water separation, clarification processes, liquid-liquid separation, and solids removal. The company’s expertise extends across diverse sectors, such as oil and gas and power generation.
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Merck Millipore
Ethylene Diamine
Company Overview
Merck Millipore, founded in 1954 and headquartered in Darmstadt, Germany, is a manufacturer, distributor, and supplier of life science products and services. Their diverse range of products finds applications in research, development, and manufacturing of biotechnological and pharmaceutical drug therapies. Some of their offerings include filters for removing contaminants from liquids and gases, chromatography columns for separating and analyzing complex mixtures, reagents used in various laboratory assays, antibodies for detecting and quantifying specific molecules, and cell culture media for growing and maintaining cells in culture. Their products and services are utilized significantly in the advancement of life sciences and drug development.
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Reagents
Ethylene Diamine
Company Overview
Reagents, established in 1997 and headquartered in New York, USA, is a manufacturer and distributor of laboratory chemicals and reagents. Serving academic institutions, research laboratories, pharmaceutical companies, and other industries, the company offers a diverse range of products that encompass organic and inorganic chemicals used in pharmaceuticals, plastics, water treatment, and more. They provide biological stains and indicators for laboratory applications like cell culture and DNA analysis, along with culture media ingredients for microbial growth. Their product portfolio also caters to applications in batteries, pigments, and catalysts. Reagents' comprehensive offerings support education, research, and manufacturing processes across various sectors.
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PCCA
Ethylene Diamine
Distributor Overview
PCCA is a supplier for compounding pharmacies, founded in 1981, and headquartered in Matraville, Australia. Its product categories include proprietary bases, devices, equipment, controlled substances, APIs, and excipients. These products enable the preparation of customized medications for patients with specific needs. The company also provides training and education for pharmacists and technicians. The company is engaged in the study and validation of pharmacy compounding technology and advancing the profession through the publication of scholarly articles.
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Ward's Science
Ethylene Diamine
Distributor Overview
Ward's Science, founded in 1996 with headquarters in the USA, is a supplier of science education materials for schools and educators across the USA. The company's products include a wide range of classroom study materials, laboratory equipment, distance learning tools, and microscopes. Ward's Science study materials cover topics including science, math, biology, and chemistry. The company also provides custom study kit solutions for geology, teachers, and students, as well as services to assist in applying for grants and science funding.
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Ethylene Diamine Manufacturer Ranking
*Including some distributors, etc.Ranking as of November 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | Oakwood Products, Inc |
14.5%
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| 2 | KANTO CHEMICAL CO.,INC. |
14.5%
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| 3 | GFS Chemicals, Inc. |
9.3%
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| 4 | Kishida Chemical Co.,Ltd. |
9.3%
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| 5 | Biotium |
8.8%
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| 6 | Junsei Chemical Co.,Ltd. |
6.2%
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| 7 | nacalai |
5.7%
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| 8 | TOMOE Engineering Co., Ltd. |
5.3%
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| 9 | Nouryon |
4.4%
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| 10 | Thermo Fisher Scientific Inc. |
4.4%
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Derivation Method
The ranking is calculated based on the click share within the ethylene diamine page as of November 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
- KANTO CHEMICAL CO.,INC.: 1,062
- TOMOE Engineering Co., Ltd.: 753
- Kishida Chemical Co.,Ltd.: 283
Newly Established Company
- Biotium: 2001 (23 years ago)
- Junsei Chemical Co.,Ltd.: 1948 (76 years ago)
- KANTO CHEMICAL CO.,INC.: 1944 (80 years ago)
Company with a History
- GFS Chemicals, Inc.: 1928 (96 years ago)
- nacalai: 1934 (90 years ago)
- TOMOE Engineering Co., Ltd.: 1941 (83 years ago)
Ethylene Diamine Manufacturers in United States
*Including some distributors, etc.
Global Distribution of Ethylene Diamine Manufacturers by Country
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
Japan
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5 | 50.0% |
United States of America
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3 | 30.0% |
Netherlands
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1 | 10.0% |
Australia
|
1 | 10.0% |
