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This section provides an overview for aminobenzoic acid as well as their applications and principles. Also, please take a look at the list of 25 aminobenzoic acid manufacturers and their company rankings. Here are the top-ranked aminobenzoic acid companies as of December, 2024: 1.MedChemExpress, 2.Spectrum Chemical Mfg. Corp., 3.HiMedia Laboratories Private Limited.
Table of Contents
Aminobenzoic Acid is a type of aromatic aminocarboxylic acid.
Aminobenzoic Acid has three isomers: o (ortho), m (meta), and p (para). o-Aminobenzoic Acid has lactogenic effects in mammals and is also known as vitamin L1. p-Aminobenzoic Acid is a precursor of folate in vivo. Aminobenzoic Acid is synthesized in vivo as a precursor to folate.
Among aminobenzoic acids, o-aminobenzoic Acid is used as a reagent for the analysis of metal ions such as cadmium, mercury, and zinc. It can also be used in the synthesis of dyes.
In contrast, p-aminobenzoic Acid is mainly used in the field of cosmetics and is used in supplements as an ingredient to assist in skin whitening because it inhibits ultraviolet rays from penetrating deep into the body and skin. As a pharmaceutical product, it can also be used as a treatment for irritable bowel syndrome.
In addition, derivatives of the esters and amides of Aminobenzoic Acid are used as local anesthetics.
o-Aminobenzoic Acid is a colorless to yellow flake or white to yellow crystalline powder. It has a density of 1.41 and a melting point of 146-148°C. o-Aminobenzoic Acid forms chelate complexes with a variety of metal ions, including mercury and cadmium. Under weakly acidic conditions the complexes form precipitates.
p-Aminobenzoic Acid is a white crystal with a melting point of 187-189°C.
The chemical formula of Aminobenzoic Acid is C7H7NO2. One amino group (-NH2) and one carboxy group (-COOH) are attached to the benzene ring. Molar mass is 137.14.
Another name for o-Aminobenzoic Acid is Anthranilic Acid. On the other hand, p-Aminobenzoic Acid is also called 4-Aminobenzoic Acid.
Figure 1. o-Aminobenzoic acid basic information
In vivo, o-aminobenzoic acid is synthesized from glutamine and chorismic acid by anthranilate synthase in the shikimic acid pathway, which is involved in the synthesis of tryptophan. Aminobenzoic Acid is a precursor to a wide variety of alkaloids.
Aminobenzoic Acid is also biosynthesized by kynurenine in the kynurenine pathway, a tryptophan metabolic pathway.
Figure 2. p-Aminobenzoic acid basic information
As a precursor to folic acid, p-aminobenzoic Acid is synthesized in vivo. p-Aminobenzoic Acid is an essential nutrient for fungi, but not for humans. The fungal enzyme converts p-aminobenzoic Acid to folic acid, but humans do not have dihydropteroate synthase.
Sulfa drugs, which are structurally similar to p-aminobenzoic Acid, inhibit the enzyme and exhibit antibacterial activity selectively against fungi.
Figure 3. Related compounds of aminobenzoic acid
Methyl anthranilate, the ester of o-Aminobenzoic Acid and methanol, is a fragrance component found in jasmine and grapes. Therefore, its main use is as a flavoring agent. Methyl anthranilate is also potent as a bird repellent and is used to protect rice, fruits, corn, sunflowers, and golf courses.
Ethyl 4-aminobenzoic Acid, the ethyl ester of p-aminobenzoic acid, is available as a local anesthetic; ethyl 4-aminobenzoic acid can numb sensory nerves and block the transmission of pain. It is formulated as an oral medication in anti-motion sickness and gastrointestinal medications to reduce nausea and stomach pain. It is also used in ointments for topical application to relieve itching and pain from insect bites, external wounds, and hemorrhoids.
*Including some distributors, etc.
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Spectrum Chemical MFG Corp. was founded in 1971, is headquartered in New Brunswick, New Jersey, and has facilities in Gardena, California. Spectrum is a fine chemical manufacturing company with an emphasis on USP, NF, FCC, BP, EP, JP, and ACS grade products, and is ISO 9001:2015 certified. Spectrum primarily serves the analytical, biopharmaceutical, food & beverage, personal care, and pharmaceutical chemicals industries. Spectrum has 4 product segments which are chemicals, equipment, supplies, and safety.
MedChemExpress (MCE), is headquartered in Monmouth Junction, New Jersey, and is a supplier of research chemicals and biochemicals for laboratory and scientific use. The company’s product range includes biochemical assay reagents, isotope-labeled compounds, inhibitory antibodies, recombinant proteins, and fluorescent dyes. These products are used in various biopharmaceutical research and development fields, including areas such as infection, cardiovascular diseases, neurodegenerative diseases, diabetes, and autoimmune diseases. The company is ISO 19001 certified and provides testing services within the ISO 17025 framework, offering bulk and custom product services and support for metrological traceability.
Santa Cruz Biotechnology, Inc., established in 1991 and headquartered in Dallas, Texas, is an American manufacturer and supplier specializing in biological products for medical research. Initially providing antibodies to the research community, they expanded their offerings to include gene silencers like siRNA and shRNA (plasmid and lentiviral), targeting all known mouse and human genes. Over time, Santa Cruz Biotechnology provides over 175,000 research biochemicals under the brand ChemCruz, including protein-interacting inhibitors, substrates, and activators, tailored for studying protein functions. The company offers monoclonal primary antibodies, designed for various mammalian and non-mammalian protein targets, along with corresponding binding secondary antibodies.
PhytoTech Labs, founded in 1997, is a manufacturer and distributor of plant research and laboratory products. The company is located in Lenexa, Kansas, and runs a European Union distribution center. They mainly supply kits, reagents, and equipment to those who deal with plant biotechnology, tissue culture, and science. They also distribute to firms involved with molecular biology, plant pathology, and defense. Additionally, they custom-manufacture several media like a woody plant, seed testing, and orchid, for clients to aid in their production and research.
AG Scientific, established in 1997 and headquartered in San Diego, United States, is an ISO 9001:2015-certified supplier of biochemicals and pharmaceutical materials for medical devices, preclinical research, bioprocessing, and diagnostic applications. The company offers a wide range of reagents and other products for molecular biology and diagnostic test development, including antibiotics, biochemicals, enzymes, inhibitors, buffers, and more. The company's products enable scientists to continue making life-changing discoveries in research centers, biotechnology companies, and pharmaceutical companies around the world.
HiMedia Laboratories Private Limited is a manufacturer of biochemicals, media, and other laboratory consumables that was established in 1975 and is headquartered in Kennett Square, Pennsylvania. Its product range includes bacterial media, cell culture media, biochemicals, enzymes, and reagents. The company's products are used by a number of industries, as diverse as biotechnology, pharmaceutical, diagnostics, and food and beverage industries. HiMedia also provides services to its customers such as custom manufacturing of microbiome sequencing where the company can custom manufacture products to meet the specific needs of its customers.
Capot Chemical Co.,Ltd was established in 1996 and is a manufacturer of custom synthesis products based in Hanghzhou, P.R. China. The company manufactures various organics products such as boronic acids, unnatural amino acids, cross linkers, chiral building blocks, and heterocyclic compounds. The management of the company have obtained the ISO 9001:2015 standards certification for the safety management system. The company have participated in various exhibitions, such as Chemspec Europe in Basel and CPhI in Barcelona, Shanghai, Milan, and Philadelphia.
TCI America (TCI) was founded in 1946 and is a worldwide manufacturer of specialty organic chemicals. The company produces organic laboratory chemicals as well as pharmaceutical, cosmetic, and functional materials. TCI’s product segments include Chemistry, Life Science, Materials Science, Analytical Chemistry, and Custom & Bulk. For materials science, the company manufactures battery materials, nanocarbon materials, and magnetic materials. For life sciences, the company produces antibodies, reagents, and chemicals for cancer research. The company produces HLC, NMR, various chemicals, and resins and media for analytical chemistry.
Loba Chemie Pvt. Ltd. is a Mumbai-based manufacturer and supplier of laboratory and fine chemicals, catering to industries such as pharmaceuticals, food, research, hospitals, and universities since its establishment in 1975. Their product range includes pH indicators, biological stains, HPLC solvents, high purity acids, and tetrazolium salts and derivatives. These products serve various applications like pH testing, cell and tissue staining, chemical separation, and pharmaceutical manufacturing. The company has several certifications, such as ISO/IEC 17025:2017 and ISO 9001:2015.
Biosynth is a Swiss manufacturer of life science reagents established in 1966 and headquartered in Staad. The company sources and manufactures biochemical products such as carbohydrates, nucleosides, and enzyme substrates, as well as various peptides and biologics. They also operate as a contract manufacturer offering custom synthesis and manufacturing services for their clients in the pharmaceutical, diagnostic, food, and agrochemical sectors. Biosynth has regional sales offices and specialized facilities in Europe and North America, including in the Netherlands, United Kingdom, and United States.
Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
Sisco Research Laboratories Pvt. Ltd., established in 1975, is an Indian manufacturer and supplier of chemicals, biochemicals, and reagents, headquartered in Mumbai, Maharashtra. Supported by Food and Drug Administration (FDA)-approved manufacturing facilities, the company offers a range of products, including general laboratory chemicals and solvents, biochemical, bioreagents, and specialty fine chemicals. Their offerings also include animal cell culture, BioLit™ range of DNA and protein tools, and nanotechnology products. Additionally, SRL provides dehydrated culture media, biological ingredients, media supplements, chromogenic media, and media kits. These products serve diverse industries such as biotechnology, confectionary and food, personal care products, pharmaceuticals, and protein purification.
LGC Standards Ltd., established in 1842, is a global British manufacturer and supplier of reference standards, headquartered in Teddington, Middlesex, with offices in 20 countries worldwide. As a subsidiary of LGC Group, the United Kingdom’s National Measurement Institute, LGC Standards also serves as the Government Chemist, providing expert opinions based on independent chemical and bioanalytical measurements. Under the business unit LGC Industrial, the company offers industrial measurement tools. Additionally, their subsidiaries, including Toronto Research Chemicals Inc (TRC) of Canada, LGC Mikromol™, and Dr. Ehrenstorfer™ of Germany, develop research tools, standards for pharmaceutical quality control, and reference materials for food and environmental analysis.
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
Carl Roth GmbH + Co. KG, established in 1879 and headquartered in Karlsruhe, Germany, is a manufacturer, distributor, and supplier of laboratory equipment, life science products, and chemicals. Their extensive product range encompasses analytical instruments, biological safety cabinets, heating mantles, pH meters, centrifuges, thermometers, and various chemicals. Their products support and facilitate laboratory research, analysis, and experimentation across various industries such as pharmaceutical, chemical, and environmental sectors. The company is certified according to DIN EN ISO 9001:2015 and DIN EN ISO 14001:2015.
Nacalai Tesque Inc., founded in 1846 and headquartered in Kyoto, Japan, is a manufacturer of research chemicals, fine chemicals, diagnostics, and the related instruments. Some of its products include cytokines, nucleic acid electrophoresis, cell dissociation reagents, and sialic acid-related products, and it also offers custom and bulk service for bulk reagents and cell culture media. The company has more than 50 domestic distributors and several worldwide, including Asia, the Middle East, Oceania, Europe, and Africa. It is ISO 9001 and ISO 9002 certified, while the Kyoto South brand and Tesque factory are ISO 14001 certified.
Founded in 1981, Central Drug House Ltd. serves the scientific community via manufacturing and marketing a library of over 9,000 products to laboratory fine chemicals and dehydrated culture media with emphasis on purity and service. Examples are acids & bases, adsorbents, disinfectants, indicator papers, oils, and solvents. CDH provides bio chemicals, research chemicals, laboratory reagents, various solvents, stains & indicators, and dehydrated culture media. CDH is ISO 9001 certified and CDHs’ products are in compliance with specifications of IP, BP, USP, and EP standards.
AdooQ BioScience, founded in 2006 and headquartered in Irvine, California, is a supplier specializing in purity inhibitors, chemical probes and reference compounds. The company's product portfolio includes inhibitors for signaling pathways, epigenetics, apoptosis, stem cells, and proteins. These products serve as tools for researchers in academia as well as the biotechnology and pharmaceutical industries, facilitating the execution of experiments, exploration of diseases, and the potential development of treatments and therapies. The company has established over 25 distributors in 30 different countries, along with service networks spanning five continents, thereby ensuring a worldwide reach.
VWR International, LLC, part of Avantor, established in 1852 and headquartered in Pennsylvania, USA, is a supplier of scientific equipment, chemicals, and furniture. The company's products include laboratory chemicals and reagents for genomics, proteomics, and microbiology, consumables and tools for laboratory operations, and critical research products for COVID-19. It also offers equipment for cleanrooms and controlled environments to maintain aseptic conditions. Its masterflex peristaltic pump systems and J.T. Baker cell lysis solutions are used for precise fluid handling and scalable bioprocessing. The company's products serve the industrial, government, and pharmaceutical markets. It provides inventory management, equipment maintenance, and business process consulting services.
PCCA is a supplier for compounding pharmacies, founded in 1981, and headquartered in Matraville, Australia. Its product categories include proprietary bases, devices, equipment, controlled substances, APIs, and excipients. These products enable the preparation of customized medications for patients with specific needs. The company also provides training and education for pharmacists and technicians. The company is engaged in the study and validation of pharmacy compounding technology and advancing the profession through the publication of scholarly articles.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | MedChemExpress |
16.7%
|
| 2 | Spectrum Chemical Mfg. Corp. |
9.3%
|
| 3 | HiMedia Laboratories Private Limited |
7.4%
|
| 4 | PhytoTech Labs |
7.4%
|
| 5 | LGC Standards |
7.4%
|
| 6 | Capot Chemical Co.,Ltd |
5.6%
|
| 7 | Santa Cruz Biotechnology, Inc. |
5.6%
|
| 8 | AdooQ BioScience |
3.7%
|
| 9 | AG Scientific |
3.7%
|
| 10 | LobaChemie Pct.Ltd. |
3.7%
|
Derivation Method
The ranking is calculated based on the click share within the aminobenzoic acid page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
United States of America
|
7 | 35.0% |
|
India
|
4 | 20.0% |
|
Japan
|
3 | 15.0% |
|
China
|
1 | 5.0% |
|
Switzerland
|
1 | 5.0% |
|
United Kingdom
|
1 | 5.0% |
|
Germany
|
1 | 5.0% |
|
Singapore
|
1 | 5.0% |
|
Australia
|
1 | 5.0% |
