CaptivA® Protein A Affinity Resin-CaptivA® Protein A Affinity Resin

CaptivA® Protein A Affinity Resin
Repligen Japan LLC

About This Product

An affordable alternative to Protein A resin, CaptivA® resin delivers industry-standard results at a fraction of the cost of traditional resins.

CaptivA® Protein A affinity resins offer high dynamic binding capacity at standard process flow rates and residence times.

■Highly reliable performance・Stability of sterilization
CaptivA® Protein A affinity resin maintains desirable dynamic binding capacity even when exposed to harsh cleaning conditions that reduce contaminants in standard feed streams. CaptivA® recombinant Protein A attachment mechanism generates multiple covalent attachment points between the ligand and the agarose beads, resulting in superior alkaline resistance compared to single point attachment properties.

・Low protein A leaching
CaptivA® Protein A affinity resin's multi-point protein chemistry ensures that Protein A leaching is constantly reduced.

・High cost efficiency
CaptivA® Protein A affinity resins are the most cost-effective chromatography resins available today, delivering industry-standard performance at a fraction of the cost of traditional affinity resins, especially when prepacked onto OPUS® chromatography columns. I will demonstrate.

CaptivA® Protein A affinity resin is made from a combination of industry standard cross-linked agarose beads and recombinant native Staphylococcal Protein A (rSPA) manufactured by Repligen, the world's leading manufacturer of recombinant Protein A.

■Ligand・Recombinant native Staphylococcus aureus Protein A (rSPA) expressed in e.coli
・Recombinant type equivalent to native Protein A
・Contains all five immunoglobin binding domains (E, D, A, B, C)
・Multi-point bonding achieved through parallel use through reductive amination

Model
There is 1 model available for this product.

Product
CaptivA® Protein A Affinity Resin

Handling Company
Repligen Japan LLC

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1 Models of CaptivA® Protein A Affinity Resin

Image	Part Number	Price (excluding tax)	Caustic stability	Particle size	Recommended flow rate	Recommended pH and temperature stability	Dynamic coupling capacity	Base matrix	Leaching amount of Protein A
	CaptivA® Protein A Affinity Resin	Available upon quote	100 cycles with 0.1M NaOH	45-165μm	30-300cm/hr	Operation: 3-10 Cleaning in place: 2-11 Temperature stability: 4-40C	44mg hIgG/mL with 6 minute residence time	4% cross-linked agarose beads	<10ng/mg IgG

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About Company Handling This Product

Repligen Japan LLC

Japan

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CaptivA® Protein A Affinity Resin Repligen Japan LLC

About This Product

■Highly reliable performance

■Ligand

1 Models of CaptivA® Protein A Affinity Resin