6 Isobutyl Nitrite Manufacturers in 2024
This section provides an overview for isobutyl nitrite as well as their applications and principles. Also, please take a look at the list of 6 isobutyl nitrite manufacturers and their company rankings. Here are the top-ranked isobutyl nitrite companies as of April, 2024: 1.Parchem, 2.Biosynth, 3.Otto Chemie Pvt. Ltd.
Table of Contents
What Is Isobutyl Nitrite?
Isobutyl nitrite, a nitrite ester formed from nitrous acid and isobutanol, has the chemical formula C4H9NO2. Its CAS No. is 542-56-3. This compound is a clear, colorless liquid at room temperature with a molecular weight of 103.12, a boiling point of 152.6 °F (67 °C), and a density of 0.87 g/mL. It is slightly soluble in water, but tends to decompose, and is miscible with organic solvents like ether and ethanol. Notably, it is highly flammable with a low flash point of -5.8 °F (-21 °C).
Uses of Isobutyl Nitrite
Isobutyl nitrite is primarily used as an additive in air fresheners and as a raw material in the production of carboxymethylcellulose, agricultural chemicals, pharmaceuticals, and plasticizers. It also serves as an antidote for cyanide poisoning and as a vasodilator. Recognized as a 'rush drug', its manufacture, import, sale, and other uses are strictly regulated, and permitted only for medical purposes and other non-harmful applications.
Principle of Isobutyl Nitrite
The chemical properties of isobutyl nitrite include its synthesis through the esterification reaction of nitrous acid and isobutanol, a common process for nitrite esters. It is hydrolyzed in the presence of a base, reverting to the original alcohol and nitrite. Highly flammable, it decomposes in water and upon heating, produces nitrogen oxides (NOx). It should not be mixed with acids or oxides due to the risk of dangerous reactions.
2. Principle of Cyanide Detoxification With Isobutyl Nitrite
Isobutyl nitrite aids in cyanide detoxification by oxidizing the Fe2+ in heme iron to Fe3+ methemoglobin, which binds with cyanide ions (CN-) to form cyanomethemoglobin. This process prevents cyanide from binding to cytochrome oxidase and causing harm. Additionally, administering sodium thiosulfate helps convert dissociated cyanide to thiocyanate, further aiding detoxification.
Types of Isobutyl Nitrite
Isobutyl nitrite is a designated drug, strictly regulated for possession and use, and currently only sold as a synthetic organic chemical reagent for research and development. Regulations restrict its use to the diagnosis, treatment, or prevention of disease and other non-harmful purposes. It is available in 25 mL, 100 mL, and 500 mL volumes and must be stored at 32-50°F (0-10°C), away from light, moisture, and heat to prevent decomposition.
List of 6 Isobutyl Nitrite Manufacturers
*Including some distributors, etc.
Sort by Features
- Default
- Company Size: largest first
- Year Founded: oldest first
- Year Founded: earliest first
Sort by Area
- United States of America
- India
- Japan
- Switzerland
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Spectrum Chemical Mfg. Corp.
Isobutyl Nitrite
Manufacturer Overview
Spectrum Chemical MFG Corp. was founded in 1971, is headquartered in New Brunswick, New Jersey, and has facilities in Gardena, California. Spectrum is a fine chemical manufacturing company with an emphasis on USP, NF, FCC, BP, EP, JP, and ACS grade products, and is ISO 9001:2015 certified. Spectrum primarily serves the analytical, biopharmaceutical, food & beverage, personal care, and pharmaceutical chemicals industries. Spectrum has 4 product segments which are chemicals, equipment, supplies, and safety.
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Parchem
Isobutyl Nitrite
Distributor Overview
Parchem was founded in 1999 and headquartered in Rochelle, New York. Parchem is a distributor of industrial chemicals. Parchem serves nutritional, personal care, pharmaceutical, and specialty chemical industries. Parchem offerings include coatings, adhesives, elastomers, industrial products, petrochemicals, oleochemicals, plastics, rubber, nutritional supplements, cosmetics, consumer products, catalysts, metallic salts, rare earths, flavors & fragrances, industrial & institutional, textiles, other food-related chemicals, dyes, finishes, chemicals for aerospace, oil gas drilling chemicals, electronics, and pharmaceuticals.
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Biosynth
Isobutyl Nitrite
Manufacturer Overview
Biosynth is a Swiss manufacturer of life science reagents established in 1966 and headquartered in Staad. The company sources and manufactures biochemical products such as carbohydrates, nucleosides, and enzyme substrates, as well as various peptides and biologics. They also operate as a contract manufacturer offering custom synthesis and manufacturing services for their clients in the pharmaceutical, diagnostic, food, and agrochemical sectors. Biosynth has regional sales offices and specialized facilities in Europe and North America, including in the Netherlands, United Kingdom, and United States.
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Tokyo Chemical Industry Co., Ltd.
Isobutyl Nitrite
Manufacturer Overview
TCI America (TCI) was founded in 1946 and is a worldwide manufacturer of specialty organic chemicals. The company produces organic laboratory chemicals as well as pharmaceutical, cosmetic, and functional materials. TCI’s product segments include Chemistry, Life Science, Materials Science, Analytical Chemistry, and Custom & Bulk. For materials science, the company manufactures battery materials, nanocarbon materials, and magnetic materials. For life sciences, the company produces antibodies, reagents, and chemicals for cancer research. The company produces HLC, NMR, various chemicals, and resins and media for analytical chemistry.
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FAR Chemical
Isobutyl Nitrite
Manufacturer Overview
FAR Chemical is a specialty chemical manufacturer and custom hazardous material packaging supplier. It is headquartered in Palm Bay, Florida, and was established in 1970. The company manufactures chemical compounds such as acetylacetonate products that are used as catalysts and crosslinkers in paints/coatings, polyurethane elastomers and foams, solvent-based pressure-sensitive adhesives, and specialty chemical processing. FAR also offers services such as custom manufacturing, contract and toll manufacturing, process development and analytical capabilities, and, specialized facilities and equipment. FAR Chemical also offers custom hazardous material packaging services, including design, fabrication, and testing. The company's customers include manufacturers, research institutions, and government agencies.
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Otto Chemie Pvt. Ltd
Isobutyl Nitrite
Distributor Overview
Founded in Mumbai, India in 2006, Otto Chemie Pvt. Ltd. is an ISO 9001:2015 & GMP certified chemical manufacturing company and distributor. Otto Chemie serves customers in many industries including agriculture and food processing, pharmaceuticals, oil & gas, cement, as well as educational and R&D industries. Product offerings include antibiotics, amino acids, vitamins, detergents, ionic liquids, materials science compounds, labware, oil, metal & ceramic science compounds and tools, oils, reagents, solvents.
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Isobutyl Nitrite Manufacturer Ranking
*Including some distributors, etc.Ranking as of April 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | Parchem |
50.0%
|
| 2 | Biosynth |
25.0%
|
| 3 | Otto Chemie Pvt. Ltd |
25.0%
|
Derivation Method
The ranking is calculated based on the click share within the isobutyl nitrite page as of April 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
- Parchem: 1999 (25 years ago)
- Spectrum Chemical Mfg. Corp.: 1971 (53 years ago)
- Biosynth: 1966 (58 years ago)
Company with a History
- Tokyo Chemical Industry Co., Ltd.: 1946 (78 years ago)
- Biosynth: 1966 (58 years ago)
- Spectrum Chemical Mfg. Corp.: 1971 (53 years ago)
Isobutyl Nitrite Manufacturers in United States
*Including some distributors, etc.
Global Distribution of Isobutyl Nitrite Manufacturers by Country
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
United States of America
|
2 | 40.0% |
Switzerland
|
1 | 20.0% |
Japan
|
1 | 20.0% |
India
|
1 | 20.0% |
