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This section provides an overview for nitros as well as their applications and principles. Also, please take a look at the list of 17 nitro manufacturers and their company rankings. Here are the top-ranked nitro companies as of December, 2024: 1.Spectrum Chemical Mfg. Corp., 2.MedChemExpress, 3.SynThink Research Chemicals.
Table of Contents
Nitro refers to a functional group commonly found in organic compounds. This group is also known as the nitro group and broadly includes nitrate esters (R-ON2). Organic compounds like nitroglycerin (specific formula: C3H5(ONO2)3) and nitrocellulose fall under nitrate esters. Trinitrotoluene (TNT, C6H2CH3(ON2)3), an explosive material, is synthesized by substituting three hydrogen atoms in the phenyl ring of toluene (C6H5CH3).
Nitro compounds have several significant applications, particularly in the fields of explosives and pharmaceuticals. In medical applications, nitro compounds like nitroglycerin are used due to their vasorelaxant effects, which widen blood vessels and are effective in treating angina attacks. Nitroglycerin is commonly administered as a sublingual tablet for angina pectoris.
In the realm of explosives, nitro compounds play a crucial role. Alfred Nobel, the founder of the Nobel Prize, notably invented dynamite, a safer explosive utilizing nitro compounds. Additionally, nitro compounds are used in the manufacture of smokeless gunpowder.
*Including some distributors, etc.
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MedChemExpress (MCE), is headquartered in Monmouth Junction, New Jersey, and is a supplier of research chemicals and biochemicals for laboratory and scientific use. The company’s product range includes biochemical assay reagents, isotope-labeled compounds, inhibitory antibodies, recombinant proteins, and fluorescent dyes. These products are used in various biopharmaceutical research and development fields, including areas such as infection, cardiovascular diseases, neurodegenerative diseases, diabetes, and autoimmune diseases. The company is ISO 19001 certified and provides testing services within the ISO 17025 framework, offering bulk and custom product services and support for metrological traceability.
Spectrum Chemical MFG Corp. was founded in 1971, is headquartered in New Brunswick, New Jersey, and has facilities in Gardena, California. Spectrum is a fine chemical manufacturing company with an emphasis on USP, NF, FCC, BP, EP, JP, and ACS grade products, and is ISO 9001:2015 certified. Spectrum primarily serves the analytical, biopharmaceutical, food & beverage, personal care, and pharmaceutical chemicals industries. Spectrum has 4 product segments which are chemicals, equipment, supplies, and safety.
California Pacific (CP) Lab Safety is an American manufacturer and distributor of laboratory safety solutions founded in Novato, California in 1996. The company produces both lab and environmental safety equipment and devices, including waste containers, safety vents, biodegradable bags, and personal protective equipment (PPE). They also offer custom design and engineering services for customer projects, as well as technical support and quality assurance. CP Lab Safety serves California’s government agencies, departments and offices, as well as clients in its research, education, and healthcare institutio.
Thermo Fisher Scientific Inc., founded in 1956 and headquartered in Waltham, Massachusetts, is a manufacturer and supplier of life science solutions, analytical instruments, specialty diagnostics, laboratory products, and biopharma services. Through its brand names, including Invitrogen, Fisher Scientific, Patheon, Applied Biosystems, and Gibco, among others, the company provides a wide range of products, which include chromatography systems, thermal cyclers, automated cell counters, fermenters, and DNA polymerases. The company’s annual revenue is over 40 billion USD, and it serves several fields, including customers working in clinical diagnostic labs, research institutions, hospitals, government agencies, and pharmaceutical/biotech companies.
Abcam Plc is a British producer and supplier of life science research materials that was established in 1998. Based in Cambridgeshire, United Kingdom, the company offers various cell and tissue products including stem cells and growth factors, proteins such as lysates and peptides, and primary as well as secondary antibodies (e.g. flow cytometry). It also provides various kits for measuring different aspects of living organisms, such as metabolism, immunology, and biomarkers. Abcam Plc serves clients in a wide range of biomedical operations, including pharmaceutical production, vaccine development, and institutional academic research.
Key Organics Ltd, founded in 1973 and headquartered in Cypress, USA, is a manufacturer of chemical products for the pharmaceutical, agrochemical and biotechnology industries. The company is an international CRO specializing in synthetic organic chemistry, providing chemistry and analytical services, as well as BIONET products for the global Life Science industries. Its BIONET portfolio consists of over 300,000 intermediates, fragments, biochemicals, and building blocks, available in ex-stock and in >95% purity with same day dispatch. The company offers bespoke chemistry solutions, from the custom synthesis of a single compound to multiple and long-term FTE projects.
CHEM-LAB NV, established in 1993, and located in Zedelgem, Belgium, is a manufacturer of reagents for diverse applications. The company offers high-purity NIST-traceable organic and inorganic standards, laboratory reagents, and CRMs for various analytical methods. Its products find applications in environmental science, water resources, food and beverage, manufacturing, and waste monitoring. Certified with ISO 9001:2000, ISO 17034, and ISO 17025, the company maintains quality standards in the production of Certified Reference Standards and Reagents.
Emco Dyestuff Pvt. Ltd., established in 1980 with headquarters in India, is a manufacturer of intermediates, industrial chemicals, solvents, and specialty chemicals used in various industries, including agrochemicals, electronics, and pharmaceuticals. Some of the company's products are ethylhexanoic acid, sodium sulfate anhydrous, Toluene Diisocyanate, and monoethylamine. The company is partnered with a number of companies, including OpenSpace Services, a manufacturer of specialty chemicals; Emco Engineering, a manufacturer of pharmaceutical machines; and Kosha Chemtech Pvt. Ltd., a software and IT support company providing simplified outsourcing solutions.
TCI America (TCI) was founded in 1946 and is a worldwide manufacturer of specialty organic chemicals. The company produces organic laboratory chemicals as well as pharmaceutical, cosmetic, and functional materials. TCI’s product segments include Chemistry, Life Science, Materials Science, Analytical Chemistry, and Custom & Bulk. For materials science, the company manufactures battery materials, nanocarbon materials, and magnetic materials. For life sciences, the company produces antibodies, reagents, and chemicals for cancer research. The company produces HLC, NMR, various chemicals, and resins and media for analytical chemistry.
Loba Chemie Pvt. Ltd. is a Mumbai-based manufacturer and supplier of laboratory and fine chemicals, catering to industries such as pharmaceuticals, food, research, hospitals, and universities since its establishment in 1975. Their product range includes pH indicators, biological stains, HPLC solvents, high purity acids, and tetrazolium salts and derivatives. These products serve various applications like pH testing, cell and tissue staining, chemical separation, and pharmaceutical manufacturing. The company has several certifications, such as ISO/IEC 17025:2017 and ISO 9001:2015.
Sarna Chemicals PVT. LTD., established in 1989 and based in Gujarat, India, is a manufacturer of dye intermediates, pigment intermediates, and specialty chemicals. The company produces products such as Bisphenol amino sulfonyl ester, 3,4 Dimethoxyaniline, 2-Nitro Dimethyl terephthalate, and Meta nitro benzoyl Chloride, and two of its manufacturing units abide by ISO-9001, ISO-14001 and OHSAS-18001. Apart from this, the company also makes products according to customer requirements and quality parameters. The company is also awarded with the export house by the Foreign Trade Policy of the Ministry of Commerce and Industry, Government of India.
Merck, started in 1668 and based in Darmstadt, Germany, is a supplier of solutions and services for research, development, and manufacture of pharmaceutical and biotechnological drug therapies. The company serves the life science industry and has a broad portfolio of 300,000 products, including biopharmaceutical manufacturing, industrial microbiology, reagent, life science research, and water purification products. It is available in 66 countries, brings together six brands, and has several ISO certifications, including ISO 13485, ISO 14001, ISO 13485, and ISO 50001.
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
Biomol GmbH, founded in 1968 and headquartered in Heidelberg, Germany, is a manufacturer, supplier, and distributor of life science products for the biomedical research domain. The company's range of products includes primary antibodies that originate from different host species such as mouse, rabbit or goat, dyes and labeling reagents, qPCR gene family primers, as well as virus-based tools used to manipulate genetic material and study viral infections. These scientific resources find applications across various disciplines, including molecular biology, academic research of drug development, pharmaceutical development of antibodies, and clinical diagnostics of viral infections.
Founded in 1981, Central Drug House Ltd. serves the scientific community via manufacturing and marketing a library of over 9,000 products to laboratory fine chemicals and dehydrated culture media with emphasis on purity and service. Examples are acids & bases, adsorbents, disinfectants, indicator papers, oils, and solvents. CDH provides bio chemicals, research chemicals, laboratory reagents, various solvents, stains & indicators, and dehydrated culture media. CDH is ISO 9001 certified and CDHs’ products are in compliance with specifications of IP, BP, USP, and EP standards.
Dojindo Laboratories, established in the 1970s by Dr. Keihei Ueno, is headquartered in Kumamoto, Japan; the company is a supplier of analytical reagents. The company's product range spans a wide array of scientific domains, from molecular biology to water analysis and beyond, utilized by research organizations, including universities, medical institutions, research institutes, and industrial facilities. The ISO 9001-accredited manufacturing facility produces over 600 standard products from categories including cell staining, oxidative stress detection, cross-linking reagents, and high-purity solvents, among others. The company supplies its products through DMT Inc. with locations in the USA, Japan, China, and Europe.
SynThink Research Chemicals, based in Pune, India, is a supplier of pharmaceutical research products to pharmaceutical and biotech companies as well as R&D labs at various research institutes and organizations. The company provides pharmaceutical reference standards, API impurities, metabolites, intermediates, building blocks and other research chemicals. It also provides custom synthesis services and contract research and development (CRO) services in the area of organic, pharmaceutical, and medicinal chemistry. The company offers custom packaging and worldwide shipping of in-stock products within 24 hours.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | Spectrum Chemical Mfg. Corp. |
28.0%
|
| 2 | MedChemExpress |
20.0%
|
| 3 | SynThink Research Chemicals |
8.0%
|
| 4 | Abcam plc |
8.0%
|
| 5 | Thermo Fisher Scientific Inc. |
8.0%
|
| 6 | DOJINDO Laboratories |
4.0%
|
| 7 | Key Organics Ltd |
4.0%
|
| 8 | CHEM-LAB NV |
4.0%
|
| 9 | Biomol GmbH |
4.0%
|
| 10 | EMCO Dyestuff PVT. LTD. |
4.0%
|
Derivation Method
The ranking is calculated based on the click share within the nitro page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
United States of America
|
5 | 33.3% |
|
India
|
5 | 33.3% |
|
Japan
|
2 | 13.3% |
|
United Kingdom
|
1 | 6.7% |
|
Belgium
|
1 | 6.7% |
|
Germany
|
1 | 6.7% |
