5 Nitroglycerin Manufacturers in 2024
This section provides an overview for nitroglycerin as well as their applications and principles. Also, please take a look at the list of 5 nitroglycerin manufacturers and their company rankings. Here are the top-ranked nitroglycerin companies as of November, 2024: 1.American Regent, Inc., 2.axplora, 3.Copperhead Chemical Company Inc..
Table of Contents
What Is Nitroglycerin?
Nitroglycerin is an organic compound used as a powerful explosive and a medicinal agent for angina pectoris. While commonly associated with the term "nitro" in both contexts, it's important to distinguish that nitroglycerin is a nitrate ester rather than a nitro compound.
The handling of undiluted nitroglycerin requires utmost care due to its extreme sensitivity to vibrations or friction, which can lead to accidental detonations. Nonetheless, with proper safety measures, the risk of explosion can be significantly reduced, although historical lack of safe handling practices led to frequent accidents.
Uses of Nitroglycerin
Nitroglycerin finds its primary applications in the fields of explosives and pharmaceuticals. Its explosive properties, triggered by heat, vibration, and friction, make it a key ingredient in dynamite, where it's mixed with nitrocellulose to create nitrogel. In dynamite, the composition includes at least 6% nitroglycerin.
Medically, nitroglycerin is utilized to treat angina pectoris. Administered as a sublingual tablet, it undergoes metabolic processes to release nitrite, which then converts to nitric oxide. This process leads to the relaxation of vascular smooth muscles and dilation of blood vessels, providing relief from angina symptoms.
Properties of Nitroglycerin
This compound is characterized by its colorless or pale yellow oily appearance, poor water solubility, and good solubility in organic solvents. It melts at 14°C and decomposes at temperatures between 50-60°C. Its high sensitivity to impact and friction necessitates careful handling to prevent accidental detonation.
Strategies to reduce nitroglycerin's sensitivity include dilution with water or acetone or its conversion into nitrogel. The compound, with the formula C3H5(ONO2)3, has a molecular weight of 227.0865g/mol and a density of 1.6g/cm3 at 15°C. Its molecular structure features tetrahedral carbon atoms and triangular nitrogen atoms.
Other Information on Nitroglycerin
1. Synthesis Method of Nitroglycerin
Discovered by Ascanio Sobrero in 1847, nitroglycerin is synthesized by esterifying glycerin with nitric acid, transforming it into a nitrate ester.
2. Storage of Nitroglycerin
To store nitroglycerin safely, it should be frozen at 8°C and is known to thaw at 14°C. The compound exhibits increased sensitivity when partially frozen, making it more prone to explosion. Repeated freeze-thaw cycles can destabilize nitroglycerin, especially in gel form, necessitating controlled temperature storage to avoid melting or freezing, especially in its dynamite form.
3. How to Use Nitroglycerin
For melting, nitroglycerin should be heated indirectly in a double boiler, ensuring that air does not become trapped around the jar's rim and avoiding stirring to prevent detonation risks. Even when in gel form, care must be taken to avoid introducing air bubbles during processing, as this can lead to explosive outcomes.
4. Compounds Related to Nitroglycerin
Nitroglycerin, a nitrate ester of glycerin, shares its origins with glycerin—a clear, colorless liquid known for its sweet taste. Glycerin's versatility sees it used in various applications, including as a preservative, sweetener, humectant, stabilizer in food, and as an ingredient in cosmetics and medicines.
List of 5 Nitroglycerin Manufacturers
*Including some distributors, etc.
Sort by Features
- Default
- Company Size: largest first
- Year Founded: oldest first
- Year Founded: earliest first
Sort by Area
- United States of America
- Germany
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American Regent, Inc.
Nitroglycerin
Manufacturer Overview
American Regent, Inc. was founded in 1967, and its headquarters is in Shirley, New York, United States, as a generic and branded speciality injectables manufacturer. American Regent, Inc. has established a status for being very responsive and dependable in its operations as a manufacturing company based in the United States, boasting a streamlined supply chain. Daily, the organization employs resourceful cognitive processes to effectively address its customers' demands by creating and distributing intricate injectable medications and products that are challenging to make.
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Copperhead Chemical Company Inc.
Nitroglycerin
Manufacturer Overview
Copperhead Chemical Company, founded in 1997 in Tamaqua, New York, is a manufacturer of pharmaceutical-grade nitroglycerin and diluted nitroglycerin mixes used in cardiac therapy and medical treatments. The company produces energetic materials for applications such as fuel additives, explosives, and propellants utilized in chemicals and health care. It has recently expanded into multifunctional cosmetic components and preservatives as part of its recent expansion. Copperhead Chemical Company provides solutions that suit customer requirements while also being environmentally responsible.
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axplora
nitroglycerin
Manufacturer Overview
Novasep, founded in 1995, is a global manufacturer in the pharmaceutical industry located in Lyon, Rhone-Alpes, France. The company specializes in API production processes and small molecule APIs for generic and has become a CDMO and API manufacturer. It also covers the entire pharmaceutical lifecycle, supporting the development and production of vital treatments. The company’s collaborative approach and combined strengths position them at the forefront of the pharmaceutical industry, driving innovation and advancing healthcare solutions.
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Flagship Biotech International Pvt Ltd
Nitroglycerine injection
Manufacturer Overview
Flagship Biotech International Private Limited, established in 2008 and located in Navi Mumbai, Maharashtra, is a manufacturer and exporter in the pharmaceutical industry. The company offers pharmaceutical products such as antibacterial medicine, anesthetic injections, and anti Diabetics tablets. It specializes in therapeutic areas such as oncology, cardiology, gynecology, and has a global footprint spanning over 45 countries. The company has earned recognition for its pharmaceutical manufacturing excellence and marketing prowess.
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Jigs chemical
Nitroglycerin
Company Overview
Jigs Chemical was established in 1998 and is based in India with global offices in the USA, UK, Canada, and Australia. Jigs Chemical is a manufacturer, distributor, and marketing & sales provider for organizations in India, specializing in chemicals and active pharmaceutical ingredients for pharmaceutical, agriculture, ceramics, metal treatment, and other industries. Jigs Chemical helps facilitate international customers to obtain chemicals from India, providing import and export assistance. Jigs Chemical’s product catalog includes over 40000 active pharmaceutical ingredients, commonly called APIs, their respective intermediates, and other chemicals.
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Nitroglycerin Manufacturer Ranking
*Including some distributors, etc.Ranking as of November 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | American Regent, Inc. |
28.7%
|
| 2 | axplora |
22.0%
|
| 3 | Copperhead Chemical Company Inc. |
19.1%
|
| 4 | Jigs chemical |
15.8%
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| 5 | Flagship Biotech International Pvt Ltd |
14.4%
|
Derivation Method
The ranking is calculated based on the click share within the nitroglycerin page as of November 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
- axplora: 2,400
Newly Established Company
- Jigs chemical: 1998 (26 years ago)
Company with a History
- Jigs chemical: 1998 (26 years ago)
Nitroglycerin Manufacturers in United States
*Including some distributors, etc.
Global Distribution of Nitroglycerin Manufacturers by Country
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
United States of America
|
2 | 66.7% |
Germany
|
1 | 33.3% |
