This section provides an overview for trimethylaluminum as well as their applications and principles. Also, please take a look at the list of 20 trimethylaluminum manufacturers and their company rankings. Here are the top-ranked trimethylaluminum companies as of November, 2024: 1.American Elements, 2.Henan Tianfu Chemical Co.,Ltd, 3.Hefei Home Sunshine Pharmaceutical Technology Co., Ltd..
Table of Contents
Trimethylaluminum (TMA) is an organic aluminum compound with the chemical formula C6H18Al2. The molecular formula is (CH3)3Al, but it exists as a dimer connected via a methyl group. It has a molecular weight of 144.18, a melting point of 15°C, a boiling point of 125°C, and is a clear, colorless liquid with a density of 0.752 g/mL at room temperature.
TMA is miscible in organic solvents such as hexane, heptane, and other aliphatic saturated hydrocarbons, toluene, and xylene. It is a volatile substance, spontaneously combustible in air and water, with a low flash point of -18°C, igniting at room temperature.
Trimethylaluminum is used in various applications, including as a raw material for producing trimethylgallium (TMG), in MO-CVD processes, and for doping silicon semiconductors. These applications are crucial in the production of LEDs and semiconductors. TMA also serves as a precursor for high-purity aluminum oxide.
In synthetic organic chemistry, it is used to make Tebbe reagents, which convert carbonyls to exo-olefins, and as a Ziegler-Natta catalyst for olefin polymerization.
Below is an explanation of the chemical properties and applications of trimethylaluminum:
As a dimeric compound connected via a methyl group, trimethylaluminum is one of the most reactive alkylaluminums with a high heat of hydrolysis. It oxidizes and ignites immediately upon contact with water. It must be handled with care to avoid contact with acids, air, amines, flammable substances, carbon halides, halogens, and oxidizing agents, preferably in inert gas or hydrocarbon solvents.
Trimethylaluminum is utilized to introduce methyl groups into metal halides, such as in the production of trimethylgallium by reacting with gallium (III) chloride. Its properties are also employed in activating titanium chloride in Ziegler-Natta catalysts for olefin polymerization and in Tebbe reagents for converting carbonyls to exo-olefins.
There are various forms of trimethylaluminum, including reagents for research and development in synthetic organic chemistry, and industrial chemical products. Laboratory reagents are commonly handled in hexane or toluene solutions with concentrations like 1.0 mol/L, 1.4 mol/L, and 2.0 mol/L, available in 100 mL, 800 mL, and 1 L volumes.
These solution products are prone to hydrolysis and may precipitate upon contact with water. Thus, they must be handled with well-dried and nitrogen-filled syringes. For industrial purposes, pure trimethylaluminum is supplied in quantities of 25g, 100g, 300g, 600g, 100mL, etc., and is stored in special containers with desiccants due to their hazardous nature.
*Including some distributors, etc.
Sort by Features
Sort by Area
American Elements was founded in 1997 in California and currently has research and production facilities in Utah, Mexico, China, and the United Kingdom. AE manufactures and distributes advanced materials from a catalog of over 30,000 products for bulk industrial use as well as small scale laboratory use. AE also provides testing and analyses services including spectroscopy along with structural, thermal, and electrical analyses. AE holds sustainable development as a core corporate value and is committed to work to protect the health of the environment.
Oakwood Chemical is based in Estill, South Carolina. The company is a producer of a wide range of organics with particular emphasis on fluorine and sulfur compounds. The company also offers custom synthesis services and bulk quantities upon request. The company has independent operations and operations in collaboration with the University of South Carolina. The company’s suppliers include ChemCollect, Chess, KISHIDA CHEMICAL Co., Ltd., and Tetramer. The company’s featured products include boronic acids and esters, peptide coupling, fluorinated amines, and reagents for synthesis.
Parchem was founded in 1999 and headquartered in Rochelle, New York. Parchem is a distributor of industrial chemicals. Parchem serves nutritional, personal care, pharmaceutical, and specialty chemical industries. Parchem offerings include coatings, adhesives, elastomers, industrial products, petrochemicals, oleochemicals, plastics, rubber, nutritional supplements, cosmetics, consumer products, catalysts, metallic salts, rare earths, flavors & fragrances, industrial & institutional, textiles, other food-related chemicals, dyes, finishes, chemicals for aerospace, oil gas drilling chemicals, electronics, and pharmaceuticals.
Tosoh Finechem Corporation is located in Shunan, Yamaguchi, Japan, and is a chemical manufacturer established in 1965 as a subsidiary of Japan’s Tosoh Corporation. The company specializes in foundational chemicals based in organometallic and halogen chemistry. These include fluorine and bromine compounds for drugs or agricultural products, organometallic catalysts for polymerization, and sodium p-styrenesulfonate used in water treatment processes. The company’s products are used mainly by specialized rubber manufacturers, pharmaceutical companies, and agro chemical producers.
Biosynth is a Swiss manufacturer of life science reagents established in 1966 and headquartered in Staad. The company sources and manufactures biochemical products such as carbohydrates, nucleosides, and enzyme substrates, as well as various peptides and biologics. They also operate as a contract manufacturer offering custom synthesis and manufacturing services for their clients in the pharmaceutical, diagnostic, food, and agrochemical sectors. Biosynth has regional sales offices and specialized facilities in Europe and North America, including in the Netherlands, United Kingdom, and United States.
Hefei Home Sunshine Pharmaceutical Technology Co., Ltd, established in 2013 and headquartered in Hefei City, China, is a manufacturer specializing in both standard and custom chemical synthesis. With manufacturing facilities in Anhui, Jiangsu, Zhejiang, and Inner Mongolia, Home Sunshine Pharma offers a range of products, including active pharmaceutical ingredients (APIs), intermediates, fine chemicals, coenzymes, and nucleotides. As an ISO 9001:2015 certified company, Home Sunshine Pharma serves research institutions, universities, and industries in Europe, America, and Southeast Asia with their chemical products.
Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
Japan Advanced Chemicals Ltd, established on March 4, 2004, and based in Atsugi-Shi, Kanagawa, Japan, is a manufacturer and supplier of CVD/ALD precursors. The company's product range includes CVD/ALD precursors for semiconductor manufacturing such as Si, Al, Ta, CVD/ALD precursors for compound semiconductors like Ga, In, Sb, CVD, and Sol-Gel products for coating including SiC, TiO2, and stainless steel canisters for chemical precursors. These products are primarily utilized in the semiconductor and coating industries. The company also provides services such as film deposition, stainless steel canister production, and small-size stainless steel canister manufacturing.
Pharmaffiliates, established in 2001 and located in Gurgaon, India, is a manufacturer of pharmaceutical standards and services. The company provides Certified Reference Standards (CRS) used in analytical methods, as well as drug delivery systems like tablets, capsules, injectables, and deuterated compounds that aid in research and development, studying drug metabolism and pharmacokinetics. Pharmaffiliates also offers various services to the pharmaceutical industry, including custom synthesis, analytical research, stability studies, and formulation development.
Nouryon has a history dating back to 1646 Sweden but was officially formed in 2018 after gaining independence from AkzoNobel. The company is a manufacturer of everyday consumer products including personal care and cleaning goods, as well as products for the agricultural, pharmaceutical, and building industries. The company’s brands include Dissolvine, Witbreak, Butanox, and Ferrazone. These brands manufacture products across five product segments: Bleaching and Oxidizing Chemicals and Technologies, Specialty Polymers, Surfactants and Chelating Agents, Polymer Production and Processing Chemicals, and Specialty Chemicals and Intermediates.
TCI America (TCI) was founded in 1946 and is a worldwide manufacturer of specialty organic chemicals. The company produces organic laboratory chemicals as well as pharmaceutical, cosmetic, and functional materials. TCI’s product segments include Chemistry, Life Science, Materials Science, Analytical Chemistry, and Custom & Bulk. For materials science, the company manufactures battery materials, nanocarbon materials, and magnetic materials. For life sciences, the company produces antibodies, reagents, and chemicals for cancer research. The company produces HLC, NMR, various chemicals, and resins and media for analytical chemistry.
Henan Tianfu Chemical Co., Ltd., founded in 2009, is a Chinese chemical manufacturer and supplier based in Zhengzhou, Henan. The company has developed over 500 compounds, mostly for fine applications in manufacturing and life science. Their product range includes electronic chemicals, ultraviolet (UV)-curing materials, ionic liquids, and pharmaceutical materials. Additionally, Henan Tianfu has expanded into the fine chemical market, offering noble metal catalysts, organic phosphine ligands, and organic light-emitting diode (OLED) intermediates. They are also involved in the development of pesticides and medical intermediates, as well as the analysis and synthesis of electronic chemical materials.
Strem Chemicals, Inc, founded in 1964, is an American manufacturer and supplier of high-purity specialty chemicals and materials, based in Newburyport, Massachusetts. Acquired by Ascensus Specialties, another American chemical company in 2021, Strem offers a catalog of over 6,000 specialty products under the metal, inorganic, organometallic, and nanomaterial categories. Some of their diverse product offerings include metal catalysts for organic synthesis, metal carbonyls, metal organic chemical vapor deposition (MOCVD) and atomic layer deposition (ALD) precursors. Strem serves global customers, particularly academic, governmental, and industrial research and development laboratories. Their products find applications in various industries, including microelectronics, chemicals, petrochemicals, and pharmaceuticals.
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
RCI Labscan Limited, founded in Thailand in 1991, is a manufacturer, supplier and distributor of laboratory equipment and chemical solvents for various industries. Its range of chemical solvents includes oxalic acid, acetone, dichloroethylene, ethanol, and hematoxylin. It also offers N-butyl acetate VLSI, a chemically purity solvent used in the electronics industry due to its low levels of metallic impurities and suitability for trace metal analysis. Zinc sulfate heptahydrate (zinc vitriol) is used for general analytical applications.The company serves as a supplier and distributor of reagents and chemical-related products for the solar PV and electronics industries.
Alfa Aesar is based in Lancashire, United Kingdom. Alfa Aesar is part of Thermo Fisher Scientific, is a manufacturer and supplier of chemicals, metals, and life science products for research and development. Alfa Aesar’s product lines include chemicals, life science, materials & metals, catalysts, and analytical & lab ware. Chemical offerings include inorganic compounds, organic compounds, organometallic, and solvents. Life sciences include biotechnology products, cellular & molecular biology, genomics, and immunology. Materials & metal include alloys, carbon, etchants, and more. Catalysts include ferrocenes, fuel cell products, and precious metals & catalysts. Alfa Aesar also offers custom manufacturing options.
Jigs Chemical was established in 1998 and is based in India with global offices in the USA, UK, Canada, and Australia. Jigs Chemical is a manufacturer, distributor, and marketing & sales provider for organizations in India, specializing in chemicals and active pharmaceutical ingredients for pharmaceutical, agriculture, ceramics, metal treatment, and other industries. Jigs Chemical helps facilitate international customers to obtain chemicals from India, providing import and export assistance. Jigs Chemical’s product catalog includes over 40000 active pharmaceutical ingredients, commonly called APIs, their respective intermediates, and other chemicals.
Xiamen Aeco Chemical Industrial Co., Ltd. was established in 2005 and has grown to become a supplier of chemical products, serving customers in various industries. Xiamen Aeco Chemical Industrial Co., Ltd. is a company based in Xiamen, China. The company specializes in the production and distribution of a wide range of chemical products, including pharmaceutical intermediates, agricultural, and other industrial. Their product line includes agrochemicals, APIs, biocides, catalysts, chemical intermediates, cosmetic raw materials, electronic chemicals, food and feed additives, inorganic chemicals, lubricant additives, organic chemicals, paints and coatings, petrochemicals, polymers, solvents, surfactants, textile auxiliary chemicals, water treatment chemicals, and more.
ChemSrc, established in 2014, is a supplier of pharmaceutical products, a chemical database platform, and a search engine. This platform serves as a gateway to an extensive repository of chemical knowledge, offering access to unique CAS-encoded product records including synthesis routes, literature references, physical and chemical properties, and supplier information. The chemical catalog spans various categories, including organic raw materials, dyes and pigments, chemical pesticides, catalysts, additives, and more. The repository information plays a vital role in supporting research and development efforts across diverse industries by fostering scientific advancements and serving as a valuable resource.
Ranking as of November 2024
Derivation MethodRank | Company | Click Share |
---|---|---|
1 | American Elements |
14.0%
|
2 | Henan Tianfu Chemical Co.,Ltd |
10.5%
|
3 | MilliporeSigma |
9.6%
|
4 | Hefei Home Sunshine Pharmaceutical Technology Co., Ltd. |
7.9%
|
5 | Japan Advanced Chemicals Ltd. |
7.9%
|
6 | Strem Chemicals, Inc |
6.1%
|
7 | Pharmaffiliates |
5.3%
|
8 | Oakwood Products, Inc |
5.3%
|
9 | Tosoh Finechem Corporation |
5.3%
|
10 | KANTO CHEMICAL CO.,INC. |
5.3%
|
Derivation Method
The ranking is calculated based on the click share within the trimethylaluminum page as of November 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
Country | Number of Companies | Share (%) |
---|---|---|
Japan | 4 | 28.6% |
United States of America | 3 | 21.4% |
China | 2 | 14.3% |
Switzerland | 1 | 7.1% |
India | 1 | 7.1% |
Netherlands | 1 | 7.1% |
Thailand | 1 | 7.1% |
United Kingdom | 1 | 7.1% |