This section provides an overview for thiosulfuric acid as well as their applications and principles. Also, please take a look at the list of 12 thiosulfuric acid manufacturers and their company rankings. Here are the top-ranked thiosulfuric acid companies as of November, 2024: 1.ChemSrc, 2.SIELC Technologies, 3.BOC Sciences.
Table of Contents
Thiosulfuric acid is a sulfur oxoacid, composed of hydrogen and thiosulfuric ions.
With the chemical formula H2S2O3, this divalent inorganic acid has a molecular weight of 114.14. Its acid dissociation constants are pKa1 = 0.6 and pKa2 = 1.6. The salts of thiosulfuric acid, including those of ammonia, alkali, and alkaline earth metals, are highly soluble in water and relatively stable in neutral or alkaline solutions.
Isolating free thiosulfuric acid is challenging, as it decomposes into colloidal sulfur and sulfur dioxide in strongly acidic solutions. While it has been isolated as a diethyl ether complex at low temperatures and in liquid carbon dioxide, these are specialized conditions.
The free acid is highly unstable, decomposing into hydrogen sulfide and sulfur trioxide, even at low temperatures. Higher temperatures accelerate its decomposition into sulfur, sulfur dioxide, and water. In air, its decomposition products are more complex, reacting with water and oxygen to form additional compounds like sulfuric acid and polythionic acid.
Due to its instability, thiosulfuric acid is not used in its raw form industrially but rather as a salt.
For instance, anhydrous sodium thiosulfate is utilized as a dechlorinating agent, dyeing aid, chrome tanning reducer for leather, neutralizer for ballast water chemicals, bathing agent, and disposable body warmers. Both crystalline and aqueous solutions of sodium thiosulfate serve similar purposes.
Thiosulfuric acid is also used in synthesizing high-value amino acids like cysteine in bacterial bodies.
Thiosulfuric acid and its ions often act as redox and chelating agents for metals. A typical redox reaction involves the reduction of halogens, where the thiosulfuric acid ion converts to a sulfate ion, making sodium thiosulfate a useful titrant in iodine titration.
As a chelating agent, it solubilizes poorly soluble silver halides into silver thiosulfate complexes, aiding in the photo fixation process. In acidic solutions, thiosulfuric acid decomposes into sulfur dioxide, combining sulfur with sulfurous acid.
Typically sold in salt form due to the difficulty of isolating the free acid, common types include sodium thiosulfate, magnesium thiosulfate, ammonium thiosulfate, and barium thiosulfate. These are available in various laboratory-friendly volumes like 25 g, 100 g, and 500 g.
The most prevalent product is sodium thiosulfate, available both as a solid and in aqueous solutions. For industrial use, "anhydrous sodium thiosulfate" is provided in larger quantities, such as 25 kg.
*Including some distributors, etc.
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THE BioTek is a manufacturer of monoclonal and polyclonal antibody that was established in 1989 and is headquartered in the City of Industry, California, USA. The company produces, per customization, a wide range of products, including chemical compounds, bioactive reagents, catalysts and ligands, materials science and inhibitors/agonists. Its products are used by a number of industries, as diverse as biotechnology, pharmaceutical, diagnostics, and academic research. THE BioTek also provides a range of services to its customers, including protein crystallization, antibody production and recombinant protein expression.
SIELC Technologies is a specialized manufacturer and developer of high-performance liquid chromatography (HPLC) columns, devices, and systems. The company was founded in 2001 and is based in Illinois, with a network of partner distributors in over 30 countries across six continents. The company's product portfolio is centered around various HPLC columns including chiral, normal- and reverse-phase, ion-exchange, and mixed-mode models. These supply clients in the biotech, pharmaceutical, petrochemical, and cannabis industries.
Junsei Chemical Co. Ltd., established in 1948 and headquartered in Tokyo, Japan, is a manufacturer of chemical reagents and chemical products, including commissioned synthesis of chemical products. Some of the products it makes include Sodium chloride solution, concentrated glycerin, calcium chloride, ascorbic acid, and nitric acid. The chemical products have a wide range of applications and can be used in pathological examination, as food additives, for analysis, and in the pharmaceutical industry. All its plants, including its research institute, are ISO4001 and ISO9001 certified, while its Saitama and Ibaraki plants are equipped with buildings that comply with GMP.
Kishida Chemical Co. Ltd., established in 1924 and headquartered in Osaka, Japan, is a manufacturer of reagents and high-purity chemicals and also does drug discovery support activities. Its product portfolio includes fine chemicals, research chemicals, ionic liquid, organic micro-analytical reagents, and chemical reagents for analysis. The products support several industries, including reagent business, battery material, drug discovery, and life science. The company is ISO 14001 certified and supplies several companies worldwide, including Meterion Advanced Chemicals Inc., Acros Organics, ChemBridge Corporation, Decon Laboratories, and InerBioScreen Ltd.
Alfa Chemistry, founded in the year 2015 is based in New York, USA as a biotechnology company and manufacturer of graphene materials. Their product portfolio includes graphene oxide, CVD graphene film, graphene modification services, graphene series, graphene-like material, carbon nanomaterials, quantum dots, upcoming nanoparticles, and graphene transfer services. The company also provides services in custom manufacturing, and graphene analysis with quality assurance. The products are used in various industries which include energy, digital electronics, environment, textile, coating, and biomedical science.
Toronto Research Chemicals Inc., founded in 1982 and based in Toronto, Canada, is a manufacturer of biochemicals and is a subsidiary of LGC Standards. The ISO 9001-certified company has an extensive catalog of over 350,000 products, including metabolites, impurities, and natural products APIs, which are used in several applications like environmental analysis, forensic science, and medicinal R&D. The company supports the scientific community across more than 120 countries and has 19 production laboratories. In 2019, it was bought by LGC, which provides components to customers in the pharmaceutical, clinical diagnostics, and food markets, among others.
Merck, started in 1668 and based in Darmstadt, Germany, is a supplier of solutions and services for research, development, and manufacture of pharmaceutical and biotechnological drug therapies. The company serves the life science industry and has a broad portfolio of 300,000 products, including biopharmaceutical manufacturing, industrial microbiology, reagent, life science research, and water purification products. It is available in 66 countries, brings together six brands, and has several ISO certifications, including ISO 13485, ISO 14001, ISO 13485, and ISO 50001.
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
Nacalai Tesque Inc., founded in 1846 and headquartered in Kyoto, Japan, is a manufacturer of research chemicals, fine chemicals, diagnostics, and the related instruments. Some of its products include cytokines, nucleic acid electrophoresis, cell dissociation reagents, and sialic acid-related products, and it also offers custom and bulk service for bulk reagents and cell culture media. The company has more than 50 domestic distributors and several worldwide, including Asia, the Middle East, Oceania, Europe, and Africa. It is ISO 9001 and ISO 9002 certified, while the Kyoto South brand and Tesque factory are ISO 14001 certified.
Vinipul Inorganics Pvt. Ltd., established in 1992 and based in Chembur, India, is an ISO 9001:2015, ISO 14001:2015, and FSSAI certified manufacturer and supplier of inorganic and industrial chemicals. The company's product portfolio includes sodium, ammonium, and potassium compounds, which are used for chemical synthesis, food preservation, and pH control. The company serves agriculture, manufacturing, and food and beverage industries. It also provides quality assurance global export and 24/7 production services to its customers.
BOC Sciences is headquartered in Shirley, New York as a brand of BOCSCI Inc. The company is a developer, manufacturer, marketer, and distributor of premium chemicals, emphasizing small molecule synthesis, biosynthesis, purification, and characterization used in academia, pharmaceuticals, biotech, CDMO, material sciences, and agriculture industries, supporting research and production. The company’s products include thousands of inhibitors, nucleotides, metabolites, and isotope-labeled products. The company offers custom synthesis and manufacturing, analytical services, antibody-drug conjugate development, and strain engineering and fermentation services.
ChemSrc, established in 2014, is a supplier of pharmaceutical products, a chemical database platform, and a search engine. This platform serves as a gateway to an extensive repository of chemical knowledge, offering access to unique CAS-encoded product records including synthesis routes, literature references, physical and chemical properties, and supplier information. The chemical catalog spans various categories, including organic raw materials, dyes and pigments, chemical pesticides, catalysts, additives, and more. The repository information plays a vital role in supporting research and development efforts across diverse industries by fostering scientific advancements and serving as a valuable resource.
Ranking as of November 2024
Derivation MethodRank | Company | Click Share |
---|---|---|
1 | ChemSrc |
33.3%
|
2 | SIELC Technologies |
33.3%
|
3 | BOC Sciences |
16.7%
|
4 | Alfa Chemistry |
16.7%
|
Derivation Method
The ranking is calculated based on the click share within the thiosulfuric acid page as of November 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
Country | Number of Companies | Share (%) |
---|---|---|
Japan | 3 | 37.5% |
United States of America | 2 | 25.0% |
United States | 1 | 12.5% |
Canada | 1 | 12.5% |
India | 1 | 12.5% |