5 Sulfonamide Manufacturers in 2024
This section provides an overview for sulfonamides as well as their applications and principles. Also, please take a look at the list of 5 sulfonamide manufacturers and their company rankings. Here are the top-ranked sulfonamide companies as of April, 2024: 1.Stratechem (I) Pvt. Ltd., 2.Manus Aktteva Biopharma LLP, 3.LGC Standards.
Table of Contents
What Is a Sulfonamide?
Sulfonamides are derivatives of alkyl sulfonic acid, synthesized through the reaction of sulfuryl chloride with ammonia or amine, characterized by the chemical structure R-SO2-NR'R". These compounds are notable for their stability against hydrolysis and hydride reduction, making them more resistant than carboxylic acid amides. They exist as aliphatic or aromatic types, depending on their carbon structure.
Uses of Sulfonamides
Sulfonamides find varied applications from serving as antibacterial agents in sulfa drugs to being used in artificial sweeteners like saccharin and plasticizers such as p-toluenesulfonamide. They work by inhibiting folic acid synthesis in microorganisms, effectively combating a range of bacteria, fungi, and certain parasites.
Properties of Sulfonamides
Typically appearing as a white to light yellow crystalline powder, sulfonamides are stable, have high melting points, and decompose to release ammonia when heated. They are soluble in water and several organic solvents, with their aqueous solutions being slightly acidic.
Other Information on Sulfonamides
1. Sulfonamide Resistance
Microorganisms can develop resistance to sulfonamides due to mutations in the folate biosynthetic enzyme, reducing the efficacy of these drugs.
2. Pharmacokinetics
Orally or topically administered sulfonamides are rapidly absorbed and distributed, metabolized in the liver, and excreted through the kidneys.
3. Precautions for Use
Usage during pregnancy or lactation is advised only if the benefits outweigh the risks, with special caution near delivery due to potential risks of neonatal and nuclear jaundice. Sulfonamides should be avoided by those with allergies to sulfonamide drugs, porphyria, and can cause side effects including hypersensitivity reactions and crystalluria, which may be mitigated by adequate hydration.
4. Sulfanilamide Skeleton
The sulfanilamide structure forms the backbone for various drugs, including thiazide diuretics and sulfonylurea diabetes medications. Those allergic to sulfonamides may also react to these classes of drugs.
List of 5 Sulfonamide Manufacturers
*Including some distributors, etc.
Sort by Features
- Default
- Company Size: largest first
- Year Founded: oldest first
- Year Founded: earliest first
Sort by Area
- India
- United Kingdom
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LGC Standards
Sulfonamides
Manufacturer Overview
LGC Standards Ltd., established in 1842, is a global British manufacturer and supplier of reference standards, headquartered in Teddington, Middlesex, with offices in 20 countries worldwide. As a subsidiary of LGC Group, the United Kingdom’s National Measurement Institute, LGC Standards also serves as the Government Chemist, providing expert opinions based on independent chemical and bioanalytical measurements. Under the business unit LGC Industrial, the company offers industrial measurement tools. Additionally, their subsidiaries, including Toronto Research Chemicals Inc (TRC) of Canada, LGC Mikromol™, and Dr. Ehrenstorfer™ of Germany, develop research tools, standards for pharmaceutical quality control, and reference materials for food and environmental analysis.
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Stratechem (I) Pvt. Ltd.
Ortho Sulfonamide
Manufacturer Overview
Stratechem (I) Pvt. Ltd., founded in India in 1976, is a manufacturer of pure aromatic like Mentha Arvensis Oil, Menthol Crystals, and Mentha Piperita Oil. The company's product range includes an array of natural isolates and essential oils, Citral Ex Lemongrass, Natural Patchouli Oil, Rose Indian Oil, and Tea Tree Oil. The company has SO 22000:2005, ISO 9001:2008, HACCP, GMP certifications for Food and Pharma, and Kosher Certifications and serves markets such as cosmetic and personal care, food and beverage and pharmaceutical.
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Manus Aktteva Biopharma LLP
Sulfonamide
Manufacturer Overview
Manus Aktteva Biopharma LLP, established in 2010 and headquartered in Ahmedabad, India, is a manufacturer, supplier, and exporter of pharmaceutical APIs, intermediates, and specialty chemicals. Their wide-ranging products cater to industries such as pharmaceutical, nutraceutical, and biotechnology. They offer Active Pharmaceutical Ingredients (APIs), the fundamental components used in various drug formulations, such as antibiotics, cardiovascular drugs, and anti-inflammatory drugs. The company also supplies specialty chemicals with unique properties applicable to diverse industries, from plastics to cosmetics manufacturing. Furthermore, the company offers custom synthesis services to meet the specific needs of their customers.
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TCI America
Sulfonamides
Company Overview
TCI America is based in Portland, Oregon, USA, and is a manufacturer and distributor of organic chemicals that was incorporated as the U.S. subsidiary of Tokyo Chemical Industry Co. Ltd. in 1985. The company specializes in producing organic chemicals used for research and development purposes. These include polymer additives, organic synthesis reagents, and chromatography columns. The company also offers contract research, bulk production, and custom synthesis services for clients in research institutions, or for production facilities with unique project specifications.
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Creative Biolabs Laboratories
Sulfonamides
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Sulfonamide Manufacturer Ranking
*Including some distributors, etc.Ranking as of April 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | Stratechem (I) Pvt. Ltd. |
66.7%
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| 2 | Manus Aktteva Biopharma LLP |
16.7%
|
| 3 | LGC Standards |
16.7%
|
Derivation Method
The ranking is calculated based on the click share within the sulfonamide page as of April 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
- Stratechem (I) Pvt. Ltd.: 20
Newly Established Company
- Stratechem (I) Pvt. Ltd.: 2003 (21 years ago)
Company with a History
- Stratechem (I) Pvt. Ltd.: 2003 (21 years ago)
Global Distribution of Sulfonamide Manufacturers by Country
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
India
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2 | 66.7% |
United Kingdom
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1 | 33.3% |
