20 Chlorocyclohexane Manufacturers in 2024
This section provides an overview for chlorocyclohexane as well as their applications and principles. Also, please take a look at the list of 20 chlorocyclohexane manufacturers and their company rankings. Here are the top-ranked chlorocyclohexane companies as of November, 2024: 1.Pharmaffiliates, 2.Key Organics Ltd, 3.Toray Industries, Inc..
Table of Contents
What Is Chlorocyclohexane?
Chlorocyclohexane is an organochlorine compound in which one hydrogen atom of cyclohexane is replaced by chlorine. Its chemical formula is C6H11Cl.
It is also called cyclohexyl chloride and exists as a liquid state with a pungent odor at room temperature.
Uses of Chlorocyclohexane
Chlorocyclohexane has various uses as an intermediate compound for agrochemical raw materials, rubber raw materials, and pharmaceuticals. The following is an example of one of these uses as a synthetic material for rubber raw materials.
Chlorocyclohexane is used to produce a substance called N-cyclohexylthiophthalimide. The phenomenon in which rubber hardens during storage or molding and becomes difficult to process is called the scorch phenomenon. N-Cyclohexylthiofthalimide acts as a scorch inhibitor in rubber processing.
Properties of Chlorocyclohexane
1. Flammability
Chlorocyclohexane is extremely flammable and is easily ignited by flame, heat or sparks. Because chlorocyclohexane contains chlorine in its composition, it can produce an irritating odor and toxic chlorine-containing gases when it burns.
Cyclocyclohexane is also highly flammable, and chlorocyclohexane, which is similar in structure to cyclohexane, is also highly flammable.
Chlorocyclohexane is less flammable than cyclohexane because of the chlorine bond. In fact, lindane, in which six of cyclohexane's hydrogens are replaced by chlorine, is nonflammable.
2. Solubility
Chlorocyclohexane is virtually insoluble in water. Quantitative solubility is 500ml per liter of water. It is very soluble in ethanol and acetone.
3. Toxicity
Chlorocyclohexane is toxic to animals and plants, including humans. This property is used as a raw material for pesticides and insecticides.
Chlorocyclohexane is a type of organochlorine compound. Organochlorine compounds are a general term for organic compounds that contain chlorine in their molecules. Most organochlorine compounds are artificially synthesized and rarely found in nature.
Most organochlorine compounds are highly toxic, and it is said that there is no organochlorine compound that is not toxic.
The use and emission of chlorofluorocarbons (CFCs), which destroy the ozone layer, and dioxin and trihalomethane, which have attracted attention for their environmental problems, are regulated by law.
Structure of Chlorocyclohexane
1. Stereo Conformation of Chlorocyclohexane
The cyclohexane ring has a strain-free three-dimensional structure called a chair conformation. It is called chair conformation because it is shaped like a lounge chair with a backrest, a seat, and a footrest. The chair-shaped cyclohexane ring has all C-C-C bond angles of 111.5°, close to the most stable tetrahedral angle of 109.5°.
In addition to the chair configuration, the cyclohexane ring has another stereo configuration called the ship-shaped configuration. This boat-shaped configuration has no angular strain, but it does have torsional strain due to the overlapping electron orbitals of the C-H bonds between adjacent carbon atoms. Therefore, it is more unstable than the chair-shaped configuration.
2. Axial and Equatorial Bonds in Chlorocyclohexane
Chlorine attached to the cyclohexane ring can take two different positions: axial and equatorial.
The axial position is parallel to the ring axis, i.e., perpendicular to the ring, while the equatorial position is around the equator of the ring, approximately in the same plane as the ring.
The equatorial position is more stable because the chlorine at the axial position is torsionally distorted due to interference with the hydrogen at the axial position.
Other Information on Chlorocyclohexane
1. Production of Chlorocyclohexane
Chlorocyclohexane is produced by chlorination of cyclohexane or by heating cyclohexanol with hydrochloric acid.
List of 20 Chlorocyclohexane Manufacturers
*Including some distributors, etc.
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Smolecule Inc.
Chlorocyclohexane
Manufacturer Overview
Smolecule Inc., founded in 2020 and headquartered in San Antonio, Texas, USA, is a manufacturer specializing in small-molecule compounds that are essential to biomedical research and pharmaceutical discovery. The company offers an array of products, including carbon nanomaterial, hydrophobic polymers, biological buffers, amino acids resin and reagents, and amino acid peptide and protein standards. These compounds have applications across various scientific disciplines, including material sciences, pharmaceutical and biopharmaceutical manufacturing, analytical chemistry, protein biology, and chemistry and biochemical research.
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Spectrum Chemical Mfg. Corp.
Chlorocyclohexane
Manufacturer Overview
Spectrum Chemical MFG Corp. was founded in 1971, is headquartered in New Brunswick, New Jersey, and has facilities in Gardena, California. Spectrum is a fine chemical manufacturing company with an emphasis on USP, NF, FCC, BP, EP, JP, and ACS grade products, and is ISO 9001:2015 certified. Spectrum primarily serves the analytical, biopharmaceutical, food & beverage, personal care, and pharmaceutical chemicals industries. Spectrum has 4 product segments which are chemicals, equipment, supplies, and safety.
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CP Lab Safety
Chlorocyclohexane, 25mL, Each
Company Overview
California Pacific (CP) Lab Safety is an American manufacturer and distributor of laboratory safety solutions founded in Novato, California in 1996. The company produces both lab and environmental safety equipment and devices, including waste containers, safety vents, biodegradable bags, and personal protective equipment (PPE). They also offer custom design and engineering services for customer projects, as well as technical support and quality assurance. CP Lab Safety serves California’s government agencies, departments and offices, as well as clients in its research, education, and healthcare institutio.
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Parchem
Chlorocyclohexane
Distributor Overview
Parchem was founded in 1999 and headquartered in Rochelle, New York. Parchem is a distributor of industrial chemicals. Parchem serves nutritional, personal care, pharmaceutical, and specialty chemical industries. Parchem offerings include coatings, adhesives, elastomers, industrial products, petrochemicals, oleochemicals, plastics, rubber, nutritional supplements, cosmetics, consumer products, catalysts, metallic salts, rare earths, flavors & fragrances, industrial & institutional, textiles, other food-related chemicals, dyes, finishes, chemicals for aerospace, oil gas drilling chemicals, electronics, and pharmaceuticals.
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KANTO CHEMICAL CO.,INC.
Chlorocyclohexane
Manufacturer Overview
Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
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Junsei Chemical Co.,Ltd.
Chlorocyclohexane
Manufacturer Overview
Junsei Chemical Co. Ltd., established in 1948 and headquartered in Tokyo, Japan, is a manufacturer of chemical reagents and chemical products, including commissioned synthesis of chemical products. Some of the products it makes include Sodium chloride solution, concentrated glycerin, calcium chloride, ascorbic acid, and nitric acid. The chemical products have a wide range of applications and can be used in pathological examination, as food additives, for analysis, and in the pharmaceutical industry. All its plants, including its research institute, are ISO4001 and ISO9001 certified, while its Saitama and Ibaraki plants are equipped with buildings that comply with GMP.
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Pharmaffiliates
1-Chlorocyclohexane-1-carbonyl Chloride
Manufacturer Overview
Pharmaffiliates, established in 2001 and located in Gurgaon, India, is a manufacturer of pharmaceutical standards and services. The company provides Certified Reference Standards (CRS) used in analytical methods, as well as drug delivery systems like tablets, capsules, injectables, and deuterated compounds that aid in research and development, studying drug metabolism and pharmacokinetics. Pharmaffiliates also offers various services to the pharmaceutical industry, including custom synthesis, analytical research, stability studies, and formulation development.
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Toronto Research Chemicals
Chlorocyclohexane
Manufacturer Overview
Toronto Research Chemicals Inc., founded in 1982 and based in Toronto, Canada, is a manufacturer of biochemicals and is a subsidiary of LGC Standards. The ISO 9001-certified company has an extensive catalog of over 350,000 products, including metabolites, impurities, and natural products APIs, which are used in several applications like environmental analysis, forensic science, and medicinal R&D. The company supports the scientific community across more than 120 countries and has 19 production laboratories. In 2019, it was bought by LGC, which provides components to customers in the pharmaceutical, clinical diagnostics, and food markets, among others.
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Shree Ganesh Remedies Limited
Chlorocyclohexane
Manufacturer Overview
Shree Ganesh Remedies Ltd., headquartered in Ankleshwar, Gujarat, India, has been a manufacturer of pharmaceutical intermediates, bulk drugs, and specialty chemicals since 1995. The company offers products including active pharmaceutical ingredients, excipients, pellets, nutraceuticals, and veterinary products such as clorsulon and trimethoprim. These products are used for formulating medicines, supplements, and animal health products to treat various conditions like infections, diabetes, hypertension, cancer, and arthritis. The quality management system (QMS) is designed to fulfill the core quality objectives of the company.
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Key Organics Ltd
Chlorocyclohexane
Manufacturer Overview
Key Organics Ltd, founded in 1973 and headquartered in Cypress, USA, is a manufacturer of chemical products for the pharmaceutical, agrochemical and biotechnology industries. The company is an international CRO specializing in synthetic organic chemistry, providing chemistry and analytical services, as well as BIONET products for the global Life Science industries. Its BIONET portfolio consists of over 300,000 intermediates, fragments, biochemicals, and building blocks, available in ex-stock and in >95% purity with same day dispatch. The company offers bespoke chemistry solutions, from the custom synthesis of a single compound to multiple and long-term FTE projects.
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Tokyo Chemical Industry Co., Ltd.
Chlorocyclohexane
Manufacturer Overview
TCI America (TCI) was founded in 1946 and is a worldwide manufacturer of specialty organic chemicals. The company produces organic laboratory chemicals as well as pharmaceutical, cosmetic, and functional materials. TCI’s product segments include Chemistry, Life Science, Materials Science, Analytical Chemistry, and Custom & Bulk. For materials science, the company manufactures battery materials, nanocarbon materials, and magnetic materials. For life sciences, the company produces antibodies, reagents, and chemicals for cancer research. The company produces HLC, NMR, various chemicals, and resins and media for analytical chemistry.
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Toray Industries, Inc.
Chlorocyclohexane
Manufacturer Overview
Toray Industries, Inc., launched in 1926 and based in Tokyo, Japan, is a manufacturer of fibers and textiles along with performance chemicals and related products. The company specializes in making fibers, textiles, resins, films, and electronics and information materials. It also presents carbon fiber composite materials plus pharmaceuticals and medical products to its customers. From raw yarn and cotton to processed and spun yarn, its fibers have been adopted in a vast range of applications including clothing, industrial, and everyday materials.
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Merck
Chlorocyclohexane
Manufacturer Overview
Merck, started in 1668 and based in Darmstadt, Germany, is a supplier of solutions and services for research, development, and manufacture of pharmaceutical and biotechnological drug therapies. The company serves the life science industry and has a broad portfolio of 300,000 products, including biopharmaceutical manufacturing, industrial microbiology, reagent, life science research, and water purification products. It is available in 66 countries, brings together six brands, and has several ISO certifications, including ISO 13485, ISO 14001, ISO 13485, and ISO 50001.
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MilliporeSigma
Chlorocyclohexane
Manufacturer Overview
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
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Alfa Aesar, Thermo Fisher Scientific.
Chlorocyclohexane
Company Overview
Alfa Aesar is based in Lancashire, United Kingdom. Alfa Aesar is part of Thermo Fisher Scientific, is a manufacturer and supplier of chemicals, metals, and life science products for research and development. Alfa Aesar’s product lines include chemicals, life science, materials & metals, catalysts, and analytical & lab ware. Chemical offerings include inorganic compounds, organic compounds, organometallic, and solvents. Life sciences include biotechnology products, cellular & molecular biology, genomics, and immunology. Materials & metal include alloys, carbon, etchants, and more. Catalysts include ferrocenes, fuel cell products, and precious metals & catalysts. Alfa Aesar also offers custom manufacturing options.
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Central Drug House
Chloro Cyclohexane for Synthesis
Company Overview
Founded in 1981, Central Drug House Ltd. serves the scientific community via manufacturing and marketing a library of over 9,000 products to laboratory fine chemicals and dehydrated culture media with emphasis on purity and service. Examples are acids & bases, adsorbents, disinfectants, indicator papers, oils, and solvents. CDH provides bio chemicals, research chemicals, laboratory reagents, various solvents, stains & indicators, and dehydrated culture media. CDH is ISO 9001 certified and CDHs’ products are in compliance with specifications of IP, BP, USP, and EP standards.
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Otto Chemie Pvt. Ltd
Chlorocyclohexane, 99%
Distributor Overview
Founded in Mumbai, India in 2006, Otto Chemie Pvt. Ltd. is an ISO 9001:2015 & GMP certified chemical manufacturing company and distributor. Otto Chemie serves customers in many industries including agriculture and food processing, pharmaceuticals, oil & gas, cement, as well as educational and R&D industries. Product offerings include antibiotics, amino acids, vitamins, detergents, ionic liquids, materials science compounds, labware, oil, metal & ceramic science compounds and tools, oils, reagents, solvents.
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Fisher Scientific
Chlorocyclohexane
Distributor Overview
Fisher Scientific UK Ltd is a supplier of laboratory chemicals, equipment, and services based in Loughborough, United Kingdom, operating as a subsidiary of Thermo Fisher Scientific, a merger of Fisher Scientific International, Inc. and Thermo Electron in 2006. With a portfolio of over 2 million products, Fisher Scientific offers chemicals, reagents, equipment and instruments, consumables, and safety products. These products cater to various sectors, including clinical diagnostic and research laboratories, pharmaceutical and biotech industries, healthcare, and government agencies. Fisher Scientific also provides business solutions like the New-Lab Start-Up program, as well as SureTRACE and SureTRACE+ for product knowledge and supply chain management.
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Trademill Technologies Pvt Ltd
Chlorocyclohexane
Distributor Overview
Trademill Technologies Pvt Ltd, founded in the United States in 1987, is a supplier of finished metal parts and assemblies and has ISO 9001 certification. The company's product portfolio includes CNC Machined Parts, Stamped and Formed Components, Turned and Milled Parts, Sheet Metal Fabrications and Extruded and Cast Components. It also provides services such as Design and Engineering Support, Prototyping and Rapid Manufacturing, Quality Control and Inspection, Surface Treatments and Coatings, and Custom Packaging and Labeling.
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Chlorocyclohexane Manufacturer Ranking
*Including some distributors, etc.Ranking as of November 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | Pharmaffiliates |
22.2%
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| 2 | Key Organics Ltd |
11.1%
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| 3 | Toray Industries, Inc. |
11.1%
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| 4 | Toronto Research Chemicals |
11.1%
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| 5 | Spectrum Chemical Mfg. Corp. |
11.1%
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| 6 | Junsei Chemical Co.,Ltd. |
11.1%
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| 7 | KANTO CHEMICAL CO.,INC. |
11.1%
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| 8 | Merck |
11.1%
|
Derivation Method
The ranking is calculated based on the click share within the chlorocyclohexane page as of November 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
- KANTO CHEMICAL CO.,INC.: 1,062
- Junsei Chemical Co.,Ltd.: 171
- Toray Industries, Inc.: 48
Newly Established Company
- Pharmaffiliates: 2001 (23 years ago)
- Parchem: 1999 (25 years ago)
- CP Lab Safety: 1996 (28 years ago)
Company with a History
- Toray Industries, Inc.: 1926 (98 years ago)
- KANTO CHEMICAL CO.,INC.: 1944 (80 years ago)
- Tokyo Chemical Industry Co., Ltd.: 1946 (78 years ago)
Chlorocyclohexane Manufacturers in United States
*Including some distributors, etc.
Global Distribution of Chlorocyclohexane Manufacturers by Country
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
United States of America
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4 | 25.0% |
Japan
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4 | 25.0% |
India
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4 | 25.0% |
United Kingdom
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3 | 18.8% |
Canada
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1 | 6.3% |
