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This section provides an overview for allylamine as well as their applications and principles. Also, please take a look at the list of 20 allylamine manufacturers and their company rankings. Here are the top-ranked allylamine companies as of December, 2024: 1.BLDpharm, 2.SRL, 3.Spectrum Chemical Mfg. Corp..
Table of Contents
Allylamine is an organic compound with the chemical formula C3H7N and the specific formula CH2=CHCH2NH2.
Its IUPAC nomenclature names are prop-2-ene-1-amine and 3-amino-1-propene; other names include 3-aminopropene, 3-aminopropylene, monoallylamine, 2-propenamine, 2-propen-1-amine, etc. Its CAS registration number is 107-11-9.
It has a molecular weight of 57.09, a melting point of -126.4°F (-88°C), and a boiling point of 131°F (55°C). It is a clear colorless to pale yellow liquid at room temperature. It has a density of 0.76 g/mL and a strong, pungent odor. It is extremely soluble in water, ethanol, and acetone.
It has an extremely low flash point of -18.4°F (-28°C). It is also a highly flammable liquid or vapor.
Allylamine is used as a raw material for agricultural chemicals, a modifier of polymer compounds, and a pharmaceutical intermediate. Some of its derivatives are also used as allylamine antifungal agents.
For example, terbinafine (trade name Lamisil) is an antifungal agent indicated for the treatment of dermatophytes and dermatomycoses caused by Candida, Sporothrix, and other fungi. One of its derivatives, diallylamine, is used as an important intermediate in industrial synthesis.
The 2-propenyl group (-CH2CH=CH2) in allylamine is called the allyl group, and the carbon position adjacent to the double bond is called the allyl position. The allyl group is distinct from the aryl group, which denotes an aromatic group, having a different structure.
The allyl group is used as a protecting group for alcohols and amines and is deprotected by palladium catalysts. In allylamine, the allyl group can also be removed by using palladium.
Carbocation, carbo-anion, and radical at the allyl position are stabilized by resonance. Therefore, allylamine tends to polymerize, forming homopolymers (polyallylamine) or copolymers. These polymers are used in reverse osmosis membranes.
Allylamines sold as products are mainly reagent products for research and development and industrial chemicals. Reagent products are available in capacities of 25 ml, 50 ml, 500 ml, 5 g, 25 g, etc. These reagent products can be handled at room temperature.
Related compounds, such as allylamine hydrochloride and poly(allylamine) solution, are also available as reagent products. Various derivatives such as diallylamine and N-allylmethylamine are also sold as reagent products for organic synthesis in many compounds.
Mixtures of allylamine (monoallylamine), diallylamine, and triallylamine are obtained by treating allyl chloride with aqueous ammonia or hexamine. Pure allylamine can also be synthesized by hydrolysis of allyl isothiocyanate.
Allylamine reacts with nitrous acid to give allyl alcohol. It can also be methylated with methyl iodide to form N-allylmethylamine. Reaction with bromine in an acidic solution leads to an addition reaction to alkenes, yielding 2,3-dibromopropylamine.
Allylamine is designated as a toxic substance. Handling in compliance with laws and regulations is required.
*Including some distributors, etc.
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Spectrum Chemical MFG Corp. was founded in 1971, is headquartered in New Brunswick, New Jersey, and has facilities in Gardena, California. Spectrum is a fine chemical manufacturing company with an emphasis on USP, NF, FCC, BP, EP, JP, and ACS grade products, and is ISO 9001:2015 certified. Spectrum primarily serves the analytical, biopharmaceutical, food & beverage, personal care, and pharmaceutical chemicals industries. Spectrum has 4 product segments which are chemicals, equipment, supplies, and safety.
Polysciences, Inc. is a manufacturer based in US Warrington, Pennsylvania and established in 1961, specializing in fine chemicals for applications in industrial, consumer, academic research, and biotechnology sectors. The company provides a wide array of products and customized solutions, as well as custom synthesis and contract manufacturing services for industries such as life sciences, bioprocessing, microparticles, medical devices, and electronic chemicals. They have recently launched a new bioprocessing brand called Kyfora Bio. With expertise in custom synthesis and contract manufacturing, they support their clients’ product manufacturing processes and expedite their time to market.
Pharmaffiliates, established in 2001 and located in Gurgaon, India, is a manufacturer of pharmaceutical standards and services. The company provides Certified Reference Standards (CRS) used in analytical methods, as well as drug delivery systems like tablets, capsules, injectables, and deuterated compounds that aid in research and development, studying drug metabolism and pharmacokinetics. Pharmaffiliates also offers various services to the pharmaceutical industry, including custom synthesis, analytical research, stability studies, and formulation development.
Toronto Research Chemicals Inc., founded in 1982 and based in Toronto, Canada, is a manufacturer of biochemicals and is a subsidiary of LGC Standards. The ISO 9001-certified company has an extensive catalog of over 350,000 products, including metabolites, impurities, and natural products APIs, which are used in several applications like environmental analysis, forensic science, and medicinal R&D. The company supports the scientific community across more than 120 countries and has 19 production laboratories. In 2019, it was bought by LGC, which provides components to customers in the pharmaceutical, clinical diagnostics, and food markets, among others.
ALPHA CHEMICA, established in 1985, is an Indian manufacturer and supplier of laboratory reagents and fine chemicals, headquartered in Mumbai, Maharashtra. Their wide range of products includes high-performance liquid chromatography (HPLC), analytical reagent/guaranteed reagent (AR/GR), laboratory reagents (LRs), and fine chemicals, catering to life science and other specialty research. During the COVID-19 pandemic and its aftermath, ALPHA CHEMICA offered BactGO, a disinfectant solution with stabilized hydrogen peroxide using silver-based chemistry, and BaVi-X, a 75% alcohol-based hand sanitizer.
FujiFilm Wako Pure Chemical Corporation, founded in 1922 and headquartered in Osaka, Japan, is a manufacturer of laboratory chemicals, specialty chemicals, and clinical diagnostic reagents. The company has three business domains, namely laboratory chemicals, specialty chemicals, and clinical diagnostic reagents, and some of its products include biochemistry reagents, blood transfusion test drugs, battery materials, polymer-related materials, and general reagents. The products are useful in various fields, including electronic, cosmetic, polymeric, pharmaceutical, and medical care. It acquired Sibayagi Co. Ltd. in 2015 and provides custom manufacturing to meet customer requirements.
Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
Enzo Life Sciences, Inc., established in 1976 and headquartered in Farmingdale, New York, is a manufacturer and provider of life sciences and diagnostic products. The company specializes in producing a diverse range of research reagents, assays, and diagnostic kits used in various fields, including genomics, immunology, and oncology. The company’s products are utilized in advancing scientific research and clinical diagnostics. The company is partnered with ALEXIS Biochemicals, Assay Designs, Stressgen, and Axxora.
Biosynth is a Swiss manufacturer of life science reagents established in 1966 and headquartered in Staad. The company sources and manufactures biochemical products such as carbohydrates, nucleosides, and enzyme substrates, as well as various peptides and biologics. They also operate as a contract manufacturer offering custom synthesis and manufacturing services for their clients in the pharmaceutical, diagnostic, food, and agrochemical sectors. Biosynth has regional sales offices and specialized facilities in Europe and North America, including in the Netherlands, United Kingdom, and United States.
Apollo Scientific Ltd, a subsidiary of Japan’s Central Glass Europe Limited, is a research chemicals manufacturer and supplier founded in 1993 and headquartered in Bredbury, United Kingdom. Performing chemical syntheses in their Manchester-based laboratories, Apollo Scientific offers a selection of over 100,000 chemical products, from fluorinated compounds to non-fluorinated building blocks, for research and industry applications. Their life science products include antibiotics and buffers, as well as customized products for stem cell, molecular biology, and proteomics research. Additionally, Apollo Scientific offers spectroscopy products, such as consumables for infrared (IR) and nuclear magnetic resonance (NMR) spectroscopy, as well as mass spectrometry standards.
TCI America (TCI) was founded in 1946 and is a worldwide manufacturer of specialty organic chemicals. The company produces organic laboratory chemicals as well as pharmaceutical, cosmetic, and functional materials. TCI’s product segments include Chemistry, Life Science, Materials Science, Analytical Chemistry, and Custom & Bulk. For materials science, the company manufactures battery materials, nanocarbon materials, and magnetic materials. For life sciences, the company produces antibodies, reagents, and chemicals for cancer research. The company produces HLC, NMR, various chemicals, and resins and media for analytical chemistry.
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
Merck, started in 1668 and based in Darmstadt, Germany, is a supplier of solutions and services for research, development, and manufacture of pharmaceutical and biotechnological drug therapies. The company serves the life science industry and has a broad portfolio of 300,000 products, including biopharmaceutical manufacturing, industrial microbiology, reagent, life science research, and water purification products. It is available in 66 countries, brings together six brands, and has several ISO certifications, including ISO 13485, ISO 14001, ISO 13485, and ISO 50001.
BLDpharm was founded in 2014 and headquartered in Shanghai, China is a manufacturer and supplier of various research chemicals. The company offers a wide range of laboratory chemicals including heterocycles, boron acids, amino acids, metal catalysts, and chiral compounds. These quality products find an array of applications as inhibitors for metabolic enzymes, pharmaceutical intermediates for antipsychotic drugs, catalysts for chiral resolving reagents, and material science for OLED material and synthesis intermediates.
Veeprho, established in 2011 and headquartered in Praha, Czech Republic, is a manufacturer of industrial chemicals. It is a chemical research company involved in the research, development, and supply of synthesized impurities, metabolites, intermediates, and active pharmaceutical ingredients (APIs) through custom synthesis. These products are utilized in the global pharmaceutical industry. Its global network is comprised of manufacturing and R&D facilities in India, as well as distribution offices in New Jersey US, and United Kingdom equipped to provide immediate support within all time zones.
Hefei TNJ Chemical Industry Co., Ltd., founded in 2001, is a chemical manufacturer and supplier in Hefei, Anhui, China. The company has a diverse product portfolio comprising over 60 key products spanning the Chemicals, Food, Pharmaceutical, and Personal Care sectors. Notable products include sophthalic acid, polylysine, as well as chlorin, and potassium acetate. To ensure product quality, the company maintains a robust quality management system that aligns with ISO 9001:2015 standards.
Alfa Aesar is based in Lancashire, United Kingdom. Alfa Aesar is part of Thermo Fisher Scientific, is a manufacturer and supplier of chemicals, metals, and life science products for research and development. Alfa Aesar’s product lines include chemicals, life science, materials & metals, catalysts, and analytical & lab ware. Chemical offerings include inorganic compounds, organic compounds, organometallic, and solvents. Life sciences include biotechnology products, cellular & molecular biology, genomics, and immunology. Materials & metal include alloys, carbon, etchants, and more. Catalysts include ferrocenes, fuel cell products, and precious metals & catalysts. Alfa Aesar also offers custom manufacturing options.
Sisco Research Laboratories Pvt. Ltd. was established in 1975 and is headquartered in Mumbai, Maharashtra, India. The company manufactures highly complex reagents and biochemicals for public and private customers across industries with over 5000 products in different grades and packing sizes across product segments. The company’s 6 product categories are General Laboratory Chemicals & Solvents, Biochemicals & Specialty Fine Chemicals, Animal Cell Culture, Nanotechnology Products, Dehydrated Culture Media & Media Kits, and Biolit™ range of DNA and Protein tools.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | BLDpharm |
13.3%
|
| 2 | SRL |
11.1%
|
| 3 | Spectrum Chemical Mfg. Corp. |
6.7%
|
| 4 | Biosynth |
5.9%
|
| 5 | FUJIFILM Wako Pure Chemical Corporation |
5.9%
|
| 6 | Merck |
5.9%
|
| 7 | Toronto Research Chemicals |
5.2%
|
| 8 | Tokyo Chemical Industry Co., Ltd. |
5.2%
|
| 9 | Enzo Life Sciences, Inc., |
4.4%
|
| 10 | Pharmaffiliates |
4.4%
|
Derivation Method
The ranking is calculated based on the click share within the allylamine page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
Japan
|
5 | 31.3% |
|
India
|
3 | 18.8% |
|
United States of America
|
2 | 12.5% |
|
United Kingdom
|
2 | 12.5% |
|
Canada
|
1 | 6.3% |
|
Italy
|
1 | 6.3% |
|
Switzerland
|
1 | 6.3% |
|
China
|
1 | 6.3% |
