7 Azulene Manufacturers in 2024
This section provides an overview for azulene as well as their applications and principles. Also, please take a look at the list of 7 azulene manufacturers and their company rankings. Here are the top-ranked azulene companies as of November, 2024: 1.MedChemExpress, 2.KANTO CHEMICAL CO.,INC., 3.Merck.
Table of Contents
What Is Azulene?
Azulene is a polycyclic aromatic hydrocarbon composed entirely of carbon and hydrogen atoms. Azulene is also the generic name for compounds that have an azulene skeleton.
Azulene is a nonbenzene aromatic compound without a benzene ring. It is a structural isomer of naphthalene and has a fused structure of 5- and 7-membered rings. It is a natural organic compound found in plants such as chamomile. The blue color, which is unusual for a hydrocarbon compound, was named "azulene" from the Spanish word "azul," meaning blue, because of this characteristic color.
Uses of Azulene
Azulene is mainly used in pharmaceuticals, cosmetics, and as an organic synthetic material due to its mild anti-inflammatory properties. It is used in gargles, medicines to reduce inflammation of the nose and throat, and drugs for gastritis and stomach ulcers.
Another azulene derivative, guaiazulene (azulone, 1,4-dimethyl-7-isopropylazulene), is used in ointments to reduce skin inflammation, cosmetics, and other daily products that come in direct contact with the skin.
Azulene is the main component of essential oils such as chamomile and chamomile. These herbs have been used as folk medicines since ancient times. Their efficacy is attributed to the anti-inflammatory properties of azulene contained in the herbs. Even today, many products use chamomile or chamomile essential oil as an ingredient in medicated bath salts and cosmetics to reduce skin inflammation, and these products can also be considered as azulene-containing daily necessities.
Properties of Azulene
| Chemical formula | C10H8 |
| English name | Azulene |
| CAS No. | 275-51-4 |
| Molecular weight | 128.17g/mol |
| Melting points | 100°C |
| Boiling point or first distillation point and boiling range | 242°C |
1. Azulene Aliases
Other names for azulene include bicyclo[5.3.0]decapentaene and cyclopentacycloheptene.
2. Solubility of Azulene
Azulene is soluble in ethanol and acetone.
Since water solubility is important for pharmaceutical use, a water-soluble azulene derivative, sodium azulene sulfonate hydrate, is often used in pharmaceutical applications.
Other Information on Azulene
1. Hazardous Properties of Azulene
Azulene is an ingredient used in pharmaceuticals and daily necessities and is not hazardous to the human body. Therefore, there is no information on azulene in the Safety Data Sheet (SDS) for chemical compounds.
2. Azulene Safety Precautionary Information
Azulene is an organic compound that is harmless to the human body, so no special safety precautions are required when handling it.
3. Other precautions
Azulene is a solid organic compound with sublimation properties. When mixtures of azulene and other organic compounds or solvents are distilled or concentrated under reduced pressure, azulene may be mixed with organic compounds or solvents with low boiling points due to azulene's sublimability. Handle and store the azulene with the sublimability of the compound in mind.
4. Disposal method
There are no legal restrictions on how to dispose of azulene. However, since azulene is often handled as a laboratory reagent or medical raw material, it should be disposed of properly by requesting a specialized waste disposal company.
List of 7 Azulene Manufacturers
*Including some distributors, etc.
Sort by Features
- Default
- Company Size: largest first
- Year Founded: oldest first
- Year Founded: earliest first
Sort by Area
- United States of America
- Canada
- Japan
- United Kingdom
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MedChemExpress
Azulene (Synonyms: Cyclopentacycloheptene)
Manufacturer Overview
MedChemExpress (MCE), is headquartered in Monmouth Junction, New Jersey, and is a supplier of research chemicals and biochemicals for laboratory and scientific use. The company’s product range includes biochemical assay reagents, isotope-labeled compounds, inhibitory antibodies, recombinant proteins, and fluorescent dyes. These products are used in various biopharmaceutical research and development fields, including areas such as infection, cardiovascular diseases, neurodegenerative diseases, diabetes, and autoimmune diseases. The company is ISO 19001 certified and provides testing services within the ISO 17025 framework, offering bulk and custom product services and support for metrological traceability.
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KANTO CHEMICAL CO.,INC.
Azulene
Manufacturer Overview
Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
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Toronto Research Chemicals
Azulene
Manufacturer Overview
Toronto Research Chemicals Inc., founded in 1982 and based in Toronto, Canada, is a manufacturer of biochemicals and is a subsidiary of LGC Standards. The ISO 9001-certified company has an extensive catalog of over 350,000 products, including metabolites, impurities, and natural products APIs, which are used in several applications like environmental analysis, forensic science, and medicinal R&D. The company supports the scientific community across more than 120 countries and has 19 production laboratories. In 2019, it was bought by LGC, which provides components to customers in the pharmaceutical, clinical diagnostics, and food markets, among others.
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Tokyo Chemical Industry Co., Ltd.
Azulene-1-carboxaldehyde
Manufacturer Overview
TCI America (TCI) was founded in 1946 and is a worldwide manufacturer of specialty organic chemicals. The company produces organic laboratory chemicals as well as pharmaceutical, cosmetic, and functional materials. TCI’s product segments include Chemistry, Life Science, Materials Science, Analytical Chemistry, and Custom & Bulk. For materials science, the company manufactures battery materials, nanocarbon materials, and magnetic materials. For life sciences, the company produces antibodies, reagents, and chemicals for cancer research. The company produces HLC, NMR, various chemicals, and resins and media for analytical chemistry.
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Merck
Azulene
Manufacturer Overview
Merck, started in 1668 and based in Darmstadt, Germany, is a supplier of solutions and services for research, development, and manufacture of pharmaceutical and biotechnological drug therapies. The company serves the life science industry and has a broad portfolio of 300,000 products, including biopharmaceutical manufacturing, industrial microbiology, reagent, life science research, and water purification products. It is available in 66 countries, brings together six brands, and has several ISO certifications, including ISO 13485, ISO 14001, ISO 13485, and ISO 50001.
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MilliporeSigma
Azulene
Manufacturer Overview
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
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Fisher Scientific
Azulene, 99%
Distributor Overview
Fisher Scientific UK Ltd is a supplier of laboratory chemicals, equipment, and services based in Loughborough, United Kingdom, operating as a subsidiary of Thermo Fisher Scientific, a merger of Fisher Scientific International, Inc. and Thermo Electron in 2006. With a portfolio of over 2 million products, Fisher Scientific offers chemicals, reagents, equipment and instruments, consumables, and safety products. These products cater to various sectors, including clinical diagnostic and research laboratories, pharmaceutical and biotech industries, healthcare, and government agencies. Fisher Scientific also provides business solutions like the New-Lab Start-Up program, as well as SureTRACE and SureTRACE+ for product knowledge and supply chain management.
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Azulene Manufacturer Ranking
*Including some distributors, etc.Ranking as of November 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | MedChemExpress |
26.1%
|
| 2 | Merck |
26.1%
|
| 3 | KANTO CHEMICAL CO.,INC. |
21.7%
|
| 4 | Toronto Research Chemicals |
17.4%
|
| 5 | Fisher Scientific |
8.7%
|
Derivation Method
The ranking is calculated based on the click share within the azulene page as of November 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
- KANTO CHEMICAL CO.,INC.: 1,062
Newly Established Company
- Toronto Research Chemicals: 1982 (42 years ago)
- Tokyo Chemical Industry Co., Ltd.: 1946 (78 years ago)
- KANTO CHEMICAL CO.,INC.: 1944 (80 years ago)
Company with a History
- KANTO CHEMICAL CO.,INC.: 1944 (80 years ago)
- Tokyo Chemical Industry Co., Ltd.: 1946 (78 years ago)
- Toronto Research Chemicals: 1982 (42 years ago)
Azulene Manufacturers in United States
*Including some distributors, etc.
Global Distribution of Azulene Manufacturers by Country
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
Japan
|
2 | 40.0% |
United States of America
|
1 | 20.0% |
Canada
|
1 | 20.0% |
United Kingdom
|
1 | 20.0% |
