23 Adiponitirile Manufacturers in 2024
This section provides an overview for adiponitirile as well as their applications and principles. Also, please take a look at the list of 23 adiponitirile manufacturers and their company rankings. Here are the top-ranked adiponitirile companies as of November, 2024: 1.East India Chemicals, 2.Molekula Americas LLC, 3.Ascend Performance Materials.
Table of Contents
What Is Adiponitirile?
Adiponitirile is a type of dinitrile, a colorless liquid at room temperature.
It is also known as "hexanedinitrile" or "1,4-dicyanobutane." It is flammable and produces toxic gases. Like other cyanide compounds, it is highly poisonous.
Uses of Adiponitirile
Adiponitirile is an important intermediate used in the manufacture of Nylon 66. The majority of its uses are in the production of nylon. Nylon 66 has properties such as high strength, abrasion resistance, and electrical insulation, and is widely used in applications such as electronics, automotive, packaging, construction, and consumer goods.
In addition to being used as a raw material for nylon, Nylon 66 is also used as an intermediate in the manufacture of rust inhibitors and rubber vulcanization accelerators. It is often used as a structure of automobiles by compositing it with glass fiber and other materials.
Properties of Adiponitirile
Adiponitirile is soluble in water, methanol, ethanol, and chloroform. Its melting point is 33.8°F (1°C) and its boiling point is 563°F (295°C). Orally, like other cyanide compounds, it is deleterious, but respirationally, it is less hazardous due to its low vapor pressure.
Its molecular formula is C6H8N2 and its molecular weight is 108.14. It is an organic compound with two cyano groups, and its differential formula is NC(CH2)4CN, with a density of 0.97 g/cm3.
Other Information on Adiponitirile
1. Examples of Adiponitirile Synthesis
Generally, adiponitirile can be obtained by dehydrating adipoamide using a catalyst, such as vanadium pentoxide. An industrialized method is the hydrocyanation of butadiene.
Acrylonitrile is also obtained by electrolytic dimerization reduction of acrylonitrile, which is produced by ammoxidation of propene.
2. Details of the Synthesis of Adiponitirile
Specifically, ammonia reacts with adipic acid produced by the oxidation of cyclohexane. The resulting ammonium adipate can be obtained by dehydration using a phosphoric acid catalyst.
It can also be synthesized by hydrocyanation of butadiene. The reaction of cyanide with butadiene in the gas phase over a copper-magnesium chromite catalyst yields 3-pentenenitrile and 4-pentenenitrile as main products.
Adiponitirile can be obtained by further reacting these products with hydrogen cyanide acid in the liquid phase using a nickel complex catalyst.
3. Reaction of Adiponitirile
Hydrogenation of adiponitirile with nickel or other catalyst yields hexamethylene diamine. The process of hydrolysis will yield adipic acid. Nylon 66 is produced by condensation polymerization of adipic acid with hexamethylene diamine produced from adiponitirile.
4. Adiponitirile as a Synthetic Intermediate for Nylon
Adiponitirile is an important compound as an intermediate in the synthesis of Nylon 66. Both hexamethylenediamine and adipic acid, which are necessary to obtain Nylon 66, can be synthesized from adiponitirile.
List of 23 Adiponitirile Manufacturers
*Including some distributors, etc.
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- Company Size: largest first
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- United States of America
- Canada
- India
- Japan
- Spain
- United Kingdom
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THE BioTek.
Adiponitirile
Manufacturer Overview
THE BioTek is a manufacturer of monoclonal and polyclonal antibody that was established in 1989 and is headquartered in the City of Industry, California, USA. The company produces, per customization, a wide range of products, including chemical compounds, bioactive reagents, catalysts and ligands, materials science and inhibitors/agonists. Its products are used by a number of industries, as diverse as biotechnology, pharmaceutical, diagnostics, and academic research. THE BioTek also provides a range of services to its customers, including protein crystallization, antibody production and recombinant protein expression.
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Spectrum Chemical Mfg. Corp.
Adiponitirile
Manufacturer Overview
Spectrum Chemical MFG Corp. was founded in 1971, is headquartered in New Brunswick, New Jersey, and has facilities in Gardena, California. Spectrum is a fine chemical manufacturing company with an emphasis on USP, NF, FCC, BP, EP, JP, and ACS grade products, and is ISO 9001:2015 certified. Spectrum primarily serves the analytical, biopharmaceutical, food & beverage, personal care, and pharmaceutical chemicals industries. Spectrum has 4 product segments which are chemicals, equipment, supplies, and safety.
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Ascend Performance Materials
Adiponitirile
Manufacturer Overview
Ascend Performance Materials is a chemical and material manufacturer based in Houston, Texas, and established in 1949. The company provides a diverse range of materials, including nylon resins, fibers, and films, as well as engineered materials such as long fiber thermoplastics and polymer modifiers. Ascend Performance Materials also offers specialized products like Acteev, an antimicrobial product line that provides long-lasting protection against bacteria, fungi, and viruses. Additionally, they offer Vydyne, a specialized product designed for engine cooling and powertrain applications. These materials cater to various industries, including automotive, electrical and electronics, and consumer goods.
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Restek Corporation.
Adiponitrile
Manufacturer Overview
Restek Corporation is a chromatography products manufacturer founded in 1985 and headquartered in Bellefonte, Pennsylvania. The company offers various products including sample preparation and collection products like solid phase extraction (SPE) cartridges, liquid chromatography (LC) and supercritical fluid chromatography (SFC) columns, and reference standards used for calibration and quality control purposes. Other products include accessories such as flow meters, regulators, and valves. These are used for monitoring the quality of soil, air, and water, as well as petrochemicals and pharmaceuticals. Restek Corporation provides clients with tech support, product education, and custom solution services.
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Santa Cruz Biotechnology, Inc.
Adiponitrile
Company Overview
Santa Cruz Biotechnology, Inc., established in 1991 and headquartered in Dallas, Texas, is an American manufacturer and supplier specializing in biological products for medical research. Initially providing antibodies to the research community, they expanded their offerings to include gene silencers like siRNA and shRNA (plasmid and lentiviral), targeting all known mouse and human genes. Over time, Santa Cruz Biotechnology provides over 175,000 research biochemicals under the brand ChemCruz, including protein-interacting inhibitors, substrates, and activators, tailored for studying protein functions. The company offers monoclonal primary antibodies, designed for various mammalian and non-mammalian protein targets, along with corresponding binding secondary antibodies.
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Molekula Americas LLC
1,4-Dicyanobutane, (Adiponitrile)
Company Overview
Molekula Group, established in 2000, is a chemical manufacturer and distributor based in Darlington, United Kingdom, supported by additional offices and warehouses in Germany, Italy, China, and the United States. The company operates two British subsidiaries, namely Scafell Organics Ltd, which manufactures fine organic chemicals, and Sherman Chemicals Ltd, which provides custom solutions across industries. The company adheres to ISO 9001:2015 standards and offers a diverse range of over 4,500 products. Their product portfolio includes analytical reagents, biochemicals, building blocks, organic and inorganic chemicals, as well as research organics and inorganics.
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Pharmaffiliates
Adiponitrile-d8
Manufacturer Overview
Pharmaffiliates, established in 2001 and located in Gurgaon, India, is a manufacturer of pharmaceutical standards and services. The company provides Certified Reference Standards (CRS) used in analytical methods, as well as drug delivery systems like tablets, capsules, injectables, and deuterated compounds that aid in research and development, studying drug metabolism and pharmacokinetics. Pharmaffiliates also offers various services to the pharmaceutical industry, including custom synthesis, analytical research, stability studies, and formulation development.
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KANTO CHEMICAL CO.,INC.
Adiponitrile
Manufacturer Overview
Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
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Toronto Research Chemicals
Adiponitrile-d8
Manufacturer Overview
Toronto Research Chemicals Inc., founded in 1982 and based in Toronto, Canada, is a manufacturer of biochemicals and is a subsidiary of LGC Standards. The ISO 9001-certified company has an extensive catalog of over 350,000 products, including metabolites, impurities, and natural products APIs, which are used in several applications like environmental analysis, forensic science, and medicinal R&D. The company supports the scientific community across more than 120 countries and has 19 production laboratories. In 2019, it was bought by LGC, which provides components to customers in the pharmaceutical, clinical diagnostics, and food markets, among others.
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Tokyo Chemical Industry Co., Ltd.
Adiponitrile
Manufacturer Overview
TCI America (TCI) was founded in 1946 and is a worldwide manufacturer of specialty organic chemicals. The company produces organic laboratory chemicals as well as pharmaceutical, cosmetic, and functional materials. TCI’s product segments include Chemistry, Life Science, Materials Science, Analytical Chemistry, and Custom & Bulk. For materials science, the company manufactures battery materials, nanocarbon materials, and magnetic materials. For life sciences, the company produces antibodies, reagents, and chemicals for cancer research. The company produces HLC, NMR, various chemicals, and resins and media for analytical chemistry.
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Kishida Chemical Co.,Ltd.
Adiponitrile
Manufacturer Overview
Kishida Chemical Co. Ltd., established in 1924 and headquartered in Osaka, Japan, is a manufacturer of reagents and high-purity chemicals and also does drug discovery support activities. Its product portfolio includes fine chemicals, research chemicals, ionic liquid, organic micro-analytical reagents, and chemical reagents for analysis. The products support several industries, including reagent business, battery material, drug discovery, and life science. The company is ISO 14001 certified and supplies several companies worldwide, including Meterion Advanced Chemicals Inc., Acros Organics, ChemBridge Corporation, Decon Laboratories, and InerBioScreen Ltd.
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Dräger
Adiponitirile
Manufacturer Overview
Dräger, established in 1889, and headquartered in Lübeck, Germany, is a manufacturer and supplier of advanced safety and medical technology products. They offer a range of solutions, including gas detection systems, respiratory protection equipment, patient monitoring systems, ventilators, and anesthesia machines, which are designed for industries such as oil and gas, chemical, firefighting, healthcare, and mining. Dräger is certified with ISO 9001 for quality management and ISO 13485 for medical devices.
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Merck
Adiponitrile
Manufacturer Overview
Merck, started in 1668 and based in Darmstadt, Germany, is a supplier of solutions and services for research, development, and manufacture of pharmaceutical and biotechnological drug therapies. The company serves the life science industry and has a broad portfolio of 300,000 products, including biopharmaceutical manufacturing, industrial microbiology, reagent, life science research, and water purification products. It is available in 66 countries, brings together six brands, and has several ISO certifications, including ISO 13485, ISO 14001, ISO 13485, and ISO 50001.
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MilliporeSigma
Adiponitrile
Manufacturer Overview
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
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nacalai
Adiponitrile
Company Overview
Nacalai Tesque Inc., founded in 1846 and headquartered in Kyoto, Japan, is a manufacturer of research chemicals, fine chemicals, diagnostics, and the related instruments. Some of its products include cytokines, nucleic acid electrophoresis, cell dissociation reagents, and sialic acid-related products, and it also offers custom and bulk service for bulk reagents and cell culture media. The company has more than 50 domestic distributors and several worldwide, including Asia, the Middle East, Oceania, Europe, and Africa. It is ISO 9001 and ISO 9002 certified, while the Kyoto South brand and Tesque factory are ISO 14001 certified.
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Alfa Aesar, Thermo Fisher Scientific.
B23122 Adiponitrile, 98%
Company Overview
Alfa Aesar is based in Lancashire, United Kingdom. Alfa Aesar is part of Thermo Fisher Scientific, is a manufacturer and supplier of chemicals, metals, and life science products for research and development. Alfa Aesar’s product lines include chemicals, life science, materials & metals, catalysts, and analytical & lab ware. Chemical offerings include inorganic compounds, organic compounds, organometallic, and solvents. Life sciences include biotechnology products, cellular & molecular biology, genomics, and immunology. Materials & metal include alloys, carbon, etchants, and more. Catalysts include ferrocenes, fuel cell products, and precious metals & catalysts. Alfa Aesar also offers custom manufacturing options.
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Merck Millipore
Adiponitrile
Company Overview
Merck Millipore, founded in 1954 and headquartered in Darmstadt, Germany, is a manufacturer, distributor, and supplier of life science products and services. Their diverse range of products finds applications in research, development, and manufacturing of biotechnological and pharmaceutical drug therapies. Some of their offerings include filters for removing contaminants from liquids and gases, chromatography columns for separating and analyzing complex mixtures, reagents used in various laboratory assays, antibodies for detecting and quantifying specific molecules, and cell culture media for growing and maintaining cells in culture. Their products and services are utilized significantly in the advancement of life sciences and drug development.
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Vizag Chemical International
Adiponitirile
Company Overview
Vizag Chemical International was founded in Andhra Pradesh, India, in 2011. Vizag Chemical International sells chemical-based products for many sectors including automotive, agriculture, airline, deodorizers, construction chemicals, boat maintenance, degreasers, detergents, drain clean products, greases, personal hygiene, lab chemicals and equipment, fuel treatment, metal treatment, tank cleaners, swimming pool and spa chemicals, scale removers, sewage chemical treatment, as well as raw chemicals. Vizag Chemical International also provides a range of services including chemical inspection, logistics, chemical usage supervision, as well as tank cleaning.
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Dytek
ADIPONITRILE
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Fisher Scientific
Adiponitrile, 98%
Distributor Overview
Fisher Scientific UK Ltd is a supplier of laboratory chemicals, equipment, and services based in Loughborough, United Kingdom, operating as a subsidiary of Thermo Fisher Scientific, a merger of Fisher Scientific International, Inc. and Thermo Electron in 2006. With a portfolio of over 2 million products, Fisher Scientific offers chemicals, reagents, equipment and instruments, consumables, and safety products. These products cater to various sectors, including clinical diagnostic and research laboratories, pharmaceutical and biotech industries, healthcare, and government agencies. Fisher Scientific also provides business solutions like the New-Lab Start-Up program, as well as SureTRACE and SureTRACE+ for product knowledge and supply chain management.
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East India Chemicals
Adiponitirile
Distributor Overview
East India Chemicals (EIC) is an Indian supplier and distributor of industrial chemicals that was established in 2008. Based in Kolkata, the company primarily offers chemicals for use in marine applications, such as biocides, degreasers, antifouling agents, and oil spill dispersants. It also offers other industrial chemicals including surfactants and solvents, as well as specialty chemicals such as polymers, lubricants, and adhesives. EIC primarily serves clients in marine and wastewater operations, as well as in the rubber, textile, and agricultural industries.
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HAZMAT Resource, Inc.
Adiponitrile, 98%
Distributor Overview
HAZMAT Resource, Inc., located in Irvine, California, USA, is a distributor of hazardous materials response equipment and materials. They specialize in personal protective equipment (PPE), testing devices, and technical reference materials for hazardous materials (hazmat) response. Their product range includes PPE such as suits, gloves, boots, and respirators to safeguard hazmat responders from dangerous substances. They offer various testing devices like meters, detectors, and kits for precise identification and measurement of hazardous materials. Additionally, the company provides technical reference materials like books, manuals, and software, equipping responders with essential knowledge on hazardous material properties and safe handling procedures.
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Adiponitirile Manufacturer Ranking
*Including some distributors, etc.Ranking as of November 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | East India Chemicals |
25.0%
|
| 2 | Molekula Americas LLC |
25.0%
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| 3 | Ascend Performance Materials |
25.0%
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| 4 | Restek Corporation. |
25.0%
|
Derivation Method
The ranking is calculated based on the click share within the adiponitirile page as of November 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
- Dräger: 16,219
- KANTO CHEMICAL CO.,INC.: 1,062
- Kishida Chemical Co.,Ltd.: 283
Newly Established Company
- Ascend Performance Materials: 2009 (15 years ago)
- Pharmaffiliates: 2001 (23 years ago)
- CYMIT QUÍMICA S.L.: 2000 (24 years ago)
Company with a History
- Dräger: 1889 (135 years ago)
- nacalai: 1934 (90 years ago)
- KANTO CHEMICAL CO.,INC.: 1944 (80 years ago)
Adiponitirile Manufacturers in United States
*Including some distributors, etc.
- THE BioTek.
- Spectrum Chemical Mfg. Corp.
- Ascend Performance Materials
- Restek Corporation.
- Santa Cruz Biotechnology, Inc.
- Molekula Americas LLC
Global Distribution of Adiponitirile Manufacturers by Country
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
United States of America
|
6 | 40.0% |
Japan
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4 | 26.7% |
United Kingdom
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2 | 13.3% |
India
|
1 | 6.7% |
Canada
|
1 | 6.7% |
Spain
|
1 | 6.7% |
