This section provides an overview for minocycline as well as their applications and principles. Also, please take a look at the list of 15 minocycline manufacturers and their company rankings. Here are the top-ranked minocycline companies as of November, 2024: 1.Teva Pharmaceuticals USA, Inc., 2.Enzo Life Sciences, Inc.,, 3.STEMCELL Technologies.
Table of Contents
Minocycline, a tetracycline antibiotic with the formula C23H27N3O7, targets the 30S ribosomal subunit in bacteria, inhibiting protein synthesis. Commonly used as minocycline hydrochloride, it appears as a yellow crystalline powder, soluble in N,N-dimethylformamide, and methanol.
Effective against a wide range of bacteria, including Gram-positive and Gram-negative bacteria, rickettsia, and chlamydia, minocycline is commonly prescribed for conditions such as prostatitis, pneumonia, cystitis, otitis, and notably, acne vulgaris.
Minocycline acts specifically on bacterial protein synthesis without affecting animal cells, offering bacteriostatic effects. It's also known to inhibit lipase activity and reduce inflammation, making it effective for acne treatment. Side effects include dizziness, nausea, and potentially more serious conditions like blood disorders and liver dysfunction at high doses.
Initial doses range from 100-200 mg, followed by maintenance doses of 100 mg every 12 to 24 hours. Tablets are preferred, but injectables are available for cases where oral intake isn't feasible.
Due to potential risks like tooth staining and enamel dysplasia in fetuses and infants, minocycline is advised with caution in pregnant and nursing women.
In the elderly and those unable to take oral medications, careful monitoring is advised due to the risk of increased vitamin K deficiency and bleeding tendencies.
Minocycline's absorption can be reduced by chelation with metals found in some foods and supplements; spacing the intake of minocycline and such substances is recommended.
To prevent esophageal irritation or ulcers, minocycline tablets should be taken with plenty of water and not immediately before lying down. Discoloration of urine or thyroid gland may occur during treatment.
*Including some distributors, etc.
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Teva Pharmaceuticals USA, Inc., founded in Tel Israel in 1901, is a manufacturer of generic and specialty medicines. The company offers a portfolio of specialty medicines including advanced therapies for complex and rare diseases, tailored to address the unique needs of patients innovative specialty pharmaceuticals, and active pharmaceutical ingredients. It collaborates with healthcare professionals to ensure our specialty medicines meet the needs of patients with complex or rare medical conditions.
Cayman Chemical Company is a manufacturer of life science research products founded in 1979 in Ann Arbor, Michigan, USA. They offer a diverse array of analytical standards, reagents, and other products for research in cancer, oxidative injury, epigenetics, neuroscience, inflammation, as well as metabolism, and other areas. The company supplies small molecules, biochemicals, assay kits, antibodies, and proteins to research scientists across academic, biotechnology, and pharmaceutical institutions. Cayman Chemical Company holds dual accreditations to ISO/IEC 17025:2017 and ISO 17034:2016 by ANAB Accreditation Services.
MedChemExpress (MCE), is headquartered in Monmouth Junction, New Jersey, and is a supplier of research chemicals and biochemicals for laboratory and scientific use. The company’s product range includes biochemical assay reagents, isotope-labeled compounds, inhibitory antibodies, recombinant proteins, and fluorescent dyes. These products are used in various biopharmaceutical research and development fields, including areas such as infection, cardiovascular diseases, neurodegenerative diseases, diabetes, and autoimmune diseases. The company is ISO 19001 certified and provides testing services within the ISO 17025 framework, offering bulk and custom product services and support for metrological traceability.
Santa Cruz Biotechnology, Inc., established in 1991 and headquartered in Dallas, Texas, is an American manufacturer and supplier specializing in biological products for medical research. Initially providing antibodies to the research community, they expanded their offerings to include gene silencers like siRNA and shRNA (plasmid and lentiviral), targeting all known mouse and human genes. Over time, Santa Cruz Biotechnology provides over 175,000 research biochemicals under the brand ChemCruz, including protein-interacting inhibitors, substrates, and activators, tailored for studying protein functions. The company offers monoclonal primary antibodies, designed for various mammalian and non-mammalian protein targets, along with corresponding binding secondary antibodies.
Bio-Techne, established in 1970 and headquartered in Minneapolis, USA, is a supplier and manufacturer of essential tools for life science research, therapeutics, and clinical diagnostics. The company offers an extensive product range, including purified proteins and reagent solutions, with a notable emphasis on cytokines and growth factors, along with antibodies, immunoassays, biologically active small molecule compounds, tissue culture reagents, and gene therapy workflow solutions, including T-Cell activation technologies. Furthermore, it provides protein analysis solutions, streamlining researchers' workflows for automated Western blot and multiplexed ELISA techniques.
Enzo Life Sciences, Inc., established in 1976 and headquartered in Farmingdale, New York, is a manufacturer and provider of life sciences and diagnostic products. The company specializes in producing a diverse range of research reagents, assays, and diagnostic kits used in various fields, including genomics, immunology, and oncology. The company’s products are utilized in advancing scientific research and clinical diagnostics. The company is partnered with ALEXIS Biochemicals, Assay Designs, Stressgen, and Axxora.
STEMCELL Technologies, founded in 1993 and headquartered in Vancouver, Canada, is a manufacturer of biotechnological products. The company specializes in developing and manufacturing tools and technologies for cell culture, cell separation, and cell analysis. Its products serve the life sciences research community, including areas like cancer research, immunology, and regenerative medicine. The company also engages in advancing scientific research and medical applications. It operates a quality management system in compliance with relevant and current regulatory requirements.
TCI America (TCI) was founded in 1946 and is a worldwide manufacturer of specialty organic chemicals. The company produces organic laboratory chemicals as well as pharmaceutical, cosmetic, and functional materials. TCI’s product segments include Chemistry, Life Science, Materials Science, Analytical Chemistry, and Custom & Bulk. For materials science, the company manufactures battery materials, nanocarbon materials, and magnetic materials. For life sciences, the company produces antibodies, reagents, and chemicals for cancer research. The company produces HLC, NMR, various chemicals, and resins and media for analytical chemistry.
Hope Pharmaceuticals Ltd, established in 1990 and headquartered in Scottsdale, Arizona, USA, is a manufacturer and supplier of various pharmaceutical products. Its product range includes injectable drugs, topical drugs, and ophthalmic drugs. Some of the products that the company offers include Sodium Thiosulfate Injection, Sodium Nitrite Injection, Sodium Bicarbonate Injection, as well as Sodium Acetate Injection, and Potassium Phosphate Injection. Its products are used for the treatment of various medical conditions.
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
Alfa Aesar is based in Lancashire, United Kingdom. Alfa Aesar is part of Thermo Fisher Scientific, is a manufacturer and supplier of chemicals, metals, and life science products for research and development. Alfa Aesar’s product lines include chemicals, life science, materials & metals, catalysts, and analytical & lab ware. Chemical offerings include inorganic compounds, organic compounds, organometallic, and solvents. Life sciences include biotechnology products, cellular & molecular biology, genomics, and immunology. Materials & metal include alloys, carbon, etchants, and more. Catalysts include ferrocenes, fuel cell products, and precious metals & catalysts. Alfa Aesar also offers custom manufacturing options.
AdooQ BioScience, founded in 2006 and headquartered in Irvine, California, is a supplier specializing in purity inhibitors, chemical probes and reference compounds. The company's product portfolio includes inhibitors for signaling pathways, epigenetics, apoptosis, stem cells, and proteins. These products serve as tools for researchers in academia as well as the biotechnology and pharmaceutical industries, facilitating the execution of experiments, exploration of diseases, and the potential development of treatments and therapies. The company has established over 25 distributors in 30 different countries, along with service networks spanning five continents, thereby ensuring a worldwide reach.
HealthWarehouse, Inc, established in 2009 and headquartered in Florence, Kentucky, USA, is an e-commerce distributor and retailer of pharmaceutical and healthcare products. It specializes in the sale of discounted brand name and generic prescription drugs, along with a wide range of over-the-counter (OTC) medical products. The company offers a comprehensive selection of healthcare essentials, including prescription medications, OTC items, diabetic supplies, medical equipment, and even pet care products. The company holds accreditation from the NABP for Digital Pharmacy and is licensed and accredited by all 50 State Boards of Pharmacy.
HAZMAT Resource, Inc., located in Irvine, California, USA, is a distributor of hazardous materials response equipment and materials. They specialize in personal protective equipment (PPE), testing devices, and technical reference materials for hazardous materials (hazmat) response. Their product range includes PPE such as suits, gloves, boots, and respirators to safeguard hazmat responders from dangerous substances. They offer various testing devices like meters, detectors, and kits for precise identification and measurement of hazardous materials. Additionally, the company provides technical reference materials like books, manuals, and software, equipping responders with essential knowledge on hazardous material properties and safe handling procedures.
Ranking as of November 2024
Derivation MethodRank | Company | Click Share |
---|---|---|
1 | Teva Pharmaceuticals USA, Inc. |
16.7%
|
2 | Enzo Life Sciences, Inc., |
12.5%
|
3 | STEMCELL Technologies |
8.3%
|
4 | Bio-Techne |
8.3%
|
5 | Cayman Chemical Company |
8.3%
|
6 | MedChemExpress |
8.3%
|
7 | Santa Cruz Biotechnology, Inc. |
8.3%
|
8 | MilliporeSigma |
8.3%
|
9 | Healthwarehouse,.Inc |
4.2%
|
10 | HAZMAT Resource, Inc. |
4.2%
|
Derivation Method
The ranking is calculated based on the click share within the minocycline page as of November 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
Country | Number of Companies | Share (%) |
---|---|---|
United States of America | 6 | 60.0% |
Italy | 1 | 10.0% |
Canada | 1 | 10.0% |
Japan | 1 | 10.0% |
United Kingdom | 1 | 10.0% |