8 Sodium Polystyrene Sulfonate Manufacturers in 2024
This section provides an overview for sodium polystyrene sulfonate as well as their applications and principles. Also, please take a look at the list of 8 sodium polystyrene sulfonate manufacturers and their company rankings. Here are the top-ranked sodium polystyrene sulfonate companies as of November, 2024: 1.Tosoh Finechem Corporation, 2.SUNRISE PHARMACEUTICAL, INC., 3.McKesson Medical-Surgical Inc..
Table of Contents
What Is Sodium Polystyrene Sulfonate?
Sodium polystyrene sulfonate is a cation-exchange resin used primarily to treat hyperkalemia by exchanging sodium ions for potassium ions in the body. This yellowish-brown powder is odorless and tasteless, and it is virtually insoluble in water, ethanol, acetone, and diethyl ether.
Uses of Sodium Polystyrene Sulfonate
This resin is indicated for hyperkalemia associated with acute and chronic renal failure. It can be administered orally or rectally, not intravenously as previously mentioned. The oral dose is typically 15 to 30 g, mixed with 20 to 100 mL of water or syrup (without sorbitol), administered one to four times a day. The rectal administration involves a similar dose suspended in a small volume of water or 2% methylcellulose solution, used particularly when oral administration is not feasible.
Properties of Sodium Polystyrene Sulfonate
As a cation-exchange resin, sodium polystyrene sulfonate operates by binding potassium ions in the colon, facilitating their removal from the body through feces. This action helps reduce high potassium levels in the blood. However, it's associated with potential side effects such as heart failure (due to increased serum sodium), gastrointestinal complications like perforation, ulcers, and necrosis (particularly with sorbitol use), and more common side effects including edema, hypocalcemia, and gastrointestinal discomfort.
Other Information on Sodium Polystyrene Sulfonate
1. Precautions for Concomitant Use
Caution is advised when used with digitalis preparations due to the risk of digitalis toxicity from lowered serum potassium levels. Antacids or laxatives containing aluminum, magnesium, or calcium, and thyroid hormones can interfere with the action of sodium polystyrene sulfonate, reducing its effectiveness or affecting thyroid hormone absorption, respectively.
2. Precautions for Use
Monitoring of serum potassium and sodium levels is essential during treatment. The risk of gastrointestinal complications underscores the importance of avoiding sorbitol-containing solutions and addressing constipation proactively. Special consideration is required when administering to pregnant or nursing women, and elderly patients may need dose adjustments due to potential physiological function impairment.
3. Difference From Calcium Polystyrene Sulfonate
While both sodium and calcium polystyrene sulfonates treat hyperkalemia, sodium variants offer a higher potassium exchange capacity, making them more effective in reducing serum potassium levels. However, calcium polystyrene sulfonate may be preferred in patients with sodium retention issues, despite its potential side effects like constipation and the risk of hypercalcemia-related complications.
List of 8 Sodium Polystyrene Sulfonate Manufacturers
*Including some distributors, etc.
Sort by Features
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- Company Size: largest first
- Year Founded: oldest first
- Year Founded: earliest first
Sort by Area
- United States of America
- Japan
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SUNRISE PHARMACEUTICAL, INC.
SODIUM POLYSTYRENE SULFONATE
Distributor Overview
Sunrise Pharmaceutical, Inc. is a pharmaceutical company that develops and manufactures generic drugs. It is headquartered in Rahway, New Jersey, and was established in 2007. The company's products include tablets, capsules, injectables, and topicals. Some of its popular products are generic versions of Lipitor, Plavix, and Advair. Sunrise Pharmaceutical also offers services such as drug discovery, clinical trials, and manufacturing. Its products are marketed to all pharmaceutical channels including local and national retailers, wholesalers, distributors, health systems, and government.
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Tosoh Finechem Corporation
ｐ-NASS
Manufacturer Overview
Tosoh Finechem Corporation is located in Shunan, Yamaguchi, Japan, and is a chemical manufacturer established in 1965 as a subsidiary of Japan’s Tosoh Corporation. The company specializes in foundational chemicals based in organometallic and halogen chemistry. These include fluorine and bromine compounds for drugs or agricultural products, organometallic catalysts for polymerization, and sodium p-styrenesulfonate used in water treatment processes. The company’s products are used mainly by specialized rubber manufacturers, pharmaceutical companies, and agro chemical producers.
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KANTO CHEMICAL CO.,INC.
Poly
Manufacturer Overview
Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
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MilliporeSigma
Poly sodium 4-styrenesulfonate
Manufacturer Overview
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
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Karger Publishers
Sodium Polystyrene Sulfonate-Induced Gastric Pneumatosis
Company Overview
Karger Publishers, founded in 1890 and headquartered in Basel, Switzerland, is a global publisher of medical and scientific content for patients, clinicians, and the scientific community. It is a family-run independent publishing house in its fourth generation, led by publisher and chairperson Gabriella Karger. Its publishing program comprises over 100 gold and platinum journals. The program comprises over 200 chief editors supported by about 5,000 editorial board members and almost 10,000 peer reviews. The research-based content is available mainly in English and relevant digital formats.
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Tufts Medical Center Community Care
Sodium Polystyrene Sulfonate, Oral/Rectal
Company Overview
Tufts Medical Center Community Care, founded in 2013 and headquartered in Braintree, Massachusetts, US, is a collaborative group of doctors, nurses, and other medical practitioners aimed at addressing the healthcare needs of local communities. Services offered include family medicine, internal medicine, gynecology, endocrinology, and gastroenterology. Other services include serving the needs of patients in need of diagnostic imaging, lab services, surgery, and urgent medical intervention. The organization comprises over 80 doctors and nurses who are skilled in caring for people of all ages, including patients with high-risk pregnancies and newborns with complex healthcare needs.
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ScriptSave WellRx
SODIUM POLYSTYRENE SULFONATE
Company Overview
ScriptSave WellRx is headquartered in Tucson, Arizona, USA, and has been a provider of prescription savings solutions since its establishment in 2002. The company offers services that help individuals access affordable medications. It specializes in delivering a comprehensive prescription savings program, offering discounts on prescription medications at participating pharmacies and assists individuals in managing their healthcare costs and improving medication adherence. The company promotes access to affordable healthcare, providing a user-friendly mobile app, and supporting individuals in finding fitting prices for their prescribed medications.
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McKesson Medical-Surgical Inc.
Kalexate Sodium Polystyrene Sulfonate
Distributor Overview
McKesson Medical-Surgical, located in the United States, is a distributor of medical supplies established in 1833. The company offers healthcare solutions, clinical resources, and distribution services. They provide a wide range of medical products with the largest delivery vehicle fleet and over 900 delivery professionals nationwide. In addition to their distribution services, they provide laboratory and pharmaceutical services, as well as solutions for inventory management. Their technology consultants offer a no-cost evaluation of the customers' supply and inventory workflow, providing with recommendations on how to drive savings and efficiencies to help uncover opportunities and match solutions to customers' specific needs.
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Sodium Polystyrene Sulfonate Manufacturer Ranking
*Including some distributors, etc.Ranking as of November 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | Tosoh Finechem Corporation |
25.9%
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| 2 | SUNRISE PHARMACEUTICAL, INC. |
18.5%
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| 3 | McKesson Medical-Surgical Inc. |
14.8%
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| 4 | ScriptSave WellRx |
11.1%
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| 5 | KANTO CHEMICAL CO.,INC. |
11.1%
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| 6 | Karger Publishers |
7.4%
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| 7 | MilliporeSigma |
7.4%
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| 8 | Tufts Medical Center Community Care |
3.7%
|
Derivation Method
The ranking is calculated based on the click share within the sodium polystyrene sulfonate page as of November 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
- KANTO CHEMICAL CO.,INC.: 1,062
Newly Established Company
- KANTO CHEMICAL CO.,INC.: 1944 (80 years ago)
- Karger Publishers: 1890 (134 years ago)
Company with a History
- Karger Publishers: 1890 (134 years ago)
- KANTO CHEMICAL CO.,INC.: 1944 (80 years ago)
Sodium Polystyrene Sulfonate Manufacturers in United States
*Including some distributors, etc.
Global Distribution of Sodium Polystyrene Sulfonate Manufacturers by Country
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
Japan
|
2 | 66.7% |
United States of America
|
1 | 33.3% |
