All Categories
History
This section provides an overview for vitamin d3 as well as their applications and principles. Also, please take a look at the list of 11 vitamin d3 manufacturers and their company rankings. Here are the top-ranked vitamin d3 companies as of December, 2024: 1.Xi'an Sonwu Biotech Co., Ltd., 2.Shaanxi Longleaf Biotechnology Co., Ltd., 3.Mitsubishi Chemical Corporation.
Table of Contents
Vitamin D3, or calciferol, is a fat-soluble vitamin, distinct from other forms like D2 (ergocalciferol). D2 and D3 are crucial for calcium and phosphorus metabolism, supporting bone health. While D2 is sourced from plants like mushrooms, D3 comes from fatty fish and can be synthesized in human skin through UVB light exposure.
Vitamin D3 is essential for bone health and calcium balance. Its deficiency can cause osteomalacia in adults and rickets in children. Besides, it offers benefits such as immune support, antioxidant properties, and potential anticancer effects. It's used in food fortification and supplements to prevent deficiencies and related diseases. The body must metabolize vitamin D3 into its active form for efficacy, making overdose risks low.
Due to limited food sources, including fish, dairy, and certain mushrooms, sunlight exposure is a primary means of obtaining adequate vitamin D3, especially in varying seasonal durations.
As a fat-soluble vitamin, vitamin D3 is stored in adipose tissue, facilitating long-term storage. It's converted into active calcitriol (1,25-dihydroxyVitamin D3) in the body, regulating calcium and phosphorus metabolism and promoting bone health. Deficiency can lead to reduced calcium absorption and bone demineralization.
Vitamin D3 has a molecular formula of C27H44O, featuring three rings and a hydrocarbon chain. Its synthesis from 7-dehydrocholesterol, and activation to calcitriol, involves enzymes CYP2R1 and CYP27B1, underlining its role in calcium metabolism.
Industrial production of vitamin D3 involves synthesizing a precursor using an aldehyde and iodomethylene compound, followed by thermal isomerization for purification. This process yields high-purity vitamin D3.
*Including some distributors, etc.
Sort by Features
Sort by Area
Mitsubishi Chemical Corporation was founded in 1933 and has a head office in Tokyo, Japan. Mitsubishi Chemical Corporation provides products including chemicals, industrial gases, and health care products to customers globally. Mitsubishi Chemical Group’s performance products division manufactures and distributes. functional food materials, electronic and electrical components, specialty chemicals, and other products. Mitsubishi Chemical health care products include pharmaceuticals, drug discovery solutions, diagnostic reagents, and instruments for medical use. Mitsubishi Chemical Corporation also provides other services such as engineering, information systems, logistics, and consulting.
Awell Ingredients Co.,Ltd., established in 2009, based in Hefei, China, is a manufacturer of functional ingredients. The company’s product portfolio includes amino acids, vitamins, food ingredients, nutritional supplements, plant extracts, and feed additives. The products’ ingredients comply with FCC, USP, BP, EP, AJI and JP standards. It also exports agents of various Chinese factories, to provide worldwide customers with competitive prices and good payment terms.The company provides products and services with endless opportunities and more economical solutions for customer products. Its main objective is to provide organic and green ingredients.
Weihai Baihe Biology Technological Co., Ltd., established in 2005, is a manufacturer of nutrition and health food in Weihai, Shandong, China. The company's main products include soft capsules, vitamin E, Omega 3, soft gel, and fish oil. It also produces multivitamins, tablets, collagen, and Co Q10 used in food, beverage, agriculture, chemical, and health sectors. The company has research and development capacity, such as OEM and ODM, with management system certification, such as BSCI, ISO 9001, OHSMS 18001, ISO 14001, and HACCP.
Zhejiang Weile Biotechnology Co., Ltd., founded in 2002 in Xinchan County, Shaoxing City, Zhejiang Province, is a manufacturer of nutritional fortification and dietary supplement solutions. The company's goods include vitamin series, hollow capsules, carotenoid series, sweeteners, and other items such as coenzyme Q10, red yeast rice, lipid acid, refined fish oil, and bird's nest acid, which are used in the beverage, food, health care, cosmetics, and nutrition industries. The company's goods have Halal, CS, Kosher, ISO, and GMP certifications.
Xi'an Sonwu Biotech Co., Ltd., incorporated in 2012, is a manufacturer and exporter specializing in herbal extracting and processing of natural plant materials in Jinye 1 Road, Xi’an, Shaanxi, China. The company’s product line has amino acids, dietary supplements, cosmetics ingredients, peptides, and nootropics used in agriculture, chemicals, food, medicine, and health sectors. The company has HSE, ISO 9001, QC 080000, GMP, and ISO 14000 management system certifications. The markets of the products are North America, Southeast Asia, Eastern Europe, the Middle East, and Africa.
Shaanxi Longleaf Biotechnology Co., Ltd., established in 2002, is a manufacturer specializing in natural extracts and other natural ingredients in Hi-Tech Zone, Xi’an, Shaanxi, China. The company's products include chemicals, food additives, cosmetics ingredients, plant extracts, and concentrate flavors. It also produces cooling agent powders, body-building series, raw powders, veterinary medicine raw materials, and concentrate flavors. The company management system certifications include ISO 20000, ISO 9001, QC 080000, HACCP, and ISO 14001.
Xi'an Harmonious Natural Biotechnology Co., Ltd., established in 2011, is a manufacturer and exporter of active pharmaceutical ingredients, hormone products, and addictives. The company products include sexual enhancement powders, animal feel addictives, weight-losing raw materials, natural sweeteners, and amino acid powder. It also produces vitamin powder, cosmetics raw materials, dietary supplements ingredients, and pesticides raw materials used in health care, cosmetics, food, and beverage industries. The company won the GMP, KOSHER, US NSF-cGMP, HALAL, and ISO quality system certifications.
Hefei Top Industry Chemical Co., Ltd. has been a manufacturer and distributor of aromatic chemicals, nutritional supplements, and food additives in Hefei, Anhui Province, China, since 2018. The company specializes in flavor ingredients, food additives, fragrance ingredients, and nutrition ingredients used in raw materials, chemicals, agriculture, and food industries. The company operates under HACCP, ISO 9001:2008, GMP, HALAL, and ISO 14001:2004. The company exports products to Asia, Oceania, Africa, the Middle East, and Europe.
China Sinopharm International (Shanghai) Co., Ltd., founded in 1985, is a manufacturer and supplier of pharmaceutical engineering productions in Jiang Ning Road, Shanghai, China. The company catalog has mask machines, active pharmaceutical ingredients, medical consumables, feed additives, and lab consumables used in IV infusion, injection production, solid preparation, and pharmaceutical production. The company has the ISO 9001 certification and is a subsidiary of China Sinopharm International Corporation and an affiliate of China National Pharmaceutical Group Corporation.
Xi'an Biohorlden Industry & Trade Co., Ltd., founded in 2021, is a manufacturer and supplier of chemicals in Chanba Ecological District, Xi’an, Shaanxi, China. The company's products include plant growth regulators, antipyretic analgesics, food additives, cosmetic intermediates, and veterinary drugs. It also produces peptides, nootropics, pharmaceuticals, raw powder, and antibiotics for the medical, food, agriculture, and healthcare industries. The company has been a Diamond Member since 2021 as an Audited Supplier.
Suzhou Greenway Biotech Co Ltd., founded in 2015, is a supplier of cosmetic ingredients, nutritional supplements, plant extracts, cosmetic peptides, and pharmaceutical intermediates located in Suzhou, China. The company supplies amino acids, natural weight loss agents, whitening anti-aging CAS, UV absorbers, and anti-dandruff agents. The products supplied are used in food, chemical, beverage, agriculture, and health. The company has ISO and GMP-certified production facilities with an established center for research and development.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | Xi'an Sonwu Biotech Co., Ltd. |
33.3%
|
| 2 | Shaanxi Longleaf Biotechnology Co., Ltd. |
33.3%
|
| 3 | Mitsubishi Chemical Corporation |
33.3%
|
Derivation Method
The ranking is calculated based on the click share within the vitamin d3 page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
China
|
7 | 87.5% |
|
Japan
|
1 | 12.5% |
