This section provides an overview for dextran sulfate sodium as well as their applications and principles. Also, please take a look at the list of 11 dextran sulfate sodium manufacturers and their company rankings. Here are the top-ranked dextran sulfate sodium companies as of November, 2024: 1.Otto Chemie Pvt. Ltd, 2.Nacalai Tesque Inc., 3.MP Biomedicals.
Table of Contents
Dextran sulfate sodium, the sodium salt of the sulfated ester of dextran, is a polymer of glucose. It is also referred to as a glycosaminoglycan. This compound is a mucopolysaccharide characterized by a repeating sugar chain structure, a degree of polymerization of approximately 40 or more, extensive length, and its exceptionally high hydrophilicity.
Common mucopolysaccharides include chondroitin sulfate, a primary component of cartilage, and hyaluronic acid, found in the connective tissue of the skin, umbilical cord, and the eye's vitreous body. Dextran sulfate sodium does not fall under any specific GHS classification categories, indicating no specific hazard information, and is considered relatively safe.
Dextran sulfate sodium serves as a skin conditioning agent and cosmetic material, offering moisturizing effects and enhancing peripheral blood flow. Additionally, it functions as an inactive dispersant, a binding agent, a treatment for dyslipidemia (hypertriglyceridemia), and an activator of lipoprotein lipase (LPL).
Beyond these applications, it is widely used in the induction of ulcerative colitis in animal models, facilitating research into colon cancer stemming from colon inflammation.
An odorless white to slightly pale yellow crystalline powder, dextran sulfate sodium is identified by CAS No. 9011-18-1. It has a molecular weight range of 36,000-50,000 according to MP Biomedicals, a pH range of 4.5-8.0, and is soluble in water but virtually insoluble in ethanol and acetone. While stable under normal conditions, it should be stored away from high temperatures, direct sunlight, moisture, and strong oxidizing agents.
Minimize contact with strong oxidizers and maintain closed containers or use local exhaust ventilation. Install safety showers and hand/eye washing facilities near work areas. Protective measures for workers include masks, gloves, goggles, or full-face glasses as necessary, and long-sleeved clothing, adhering to industrial hygiene and safety standards.
Avoid ingestion, inhalation, and dermal exposure during work, ensuring thorough washing and gargling post-handling. Also, prevent contaminated protective gear from leaving the work area.
For inhalation, seek fresh air and medical advice if symptoms persist. In case of skin contact, wash immediately with soap and plenty of water. If the substance enters the eyes, rinse carefully for several minutes, remove contact lenses if applicable, and seek medical attention if symptoms continue. If ingested, rinse the mouth, avoid giving anything by mouth if unconscious, and consult medical professionals with SDS and handling information at hand.
In the event of a fire, use water spray, carbon dioxide (CO2), foam, powder, or sand to extinguish. Since no specific fire extinguishing agent is prohibited, select an agent suitable for the surrounding environment. Firefighters should wear appropriate protective equipment, including self-contained breathing apparatus.
Store in a cool, well-ventilated area away from direct sunlight, in tightly sealed glass containers, and distant from strong oxidizers. Dispose of this product through a licensed waste disposal contractor, following relevant regional, national, and local regulations.
*Including some distributors, etc.
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Cayman Chemical Company is a manufacturer of life science research products founded in 1979 in Ann Arbor, Michigan, USA. They offer a diverse array of analytical standards, reagents, and other products for research in cancer, oxidative injury, epigenetics, neuroscience, inflammation, as well as metabolism, and other areas. The company supplies small molecules, biochemicals, assay kits, antibodies, and proteins to research scientists across academic, biotechnology, and pharmaceutical institutions. Cayman Chemical Company holds dual accreditations to ISO/IEC 17025:2017 and ISO 17034:2016 by ANAB Accreditation Services.
Spectrum Chemical MFG Corp. was founded in 1971, is headquartered in New Brunswick, New Jersey, and has facilities in Gardena, California. Spectrum is a fine chemical manufacturing company with an emphasis on USP, NF, FCC, BP, EP, JP, and ACS grade products, and is ISO 9001:2015 certified. Spectrum primarily serves the analytical, biopharmaceutical, food & beverage, personal care, and pharmaceutical chemicals industries. Spectrum has 4 product segments which are chemicals, equipment, supplies, and safety.
BioSpectra, Inc., established in 1993 and headquartered in Bangor, Pennsylvania, is a manufacturer and supplier of high-purity biochemicals and enzymes. The company offers a diverse range of products, including pharmaceutical-grade sugars, buffers, amino acids, nucleotides, and enzymes. These products serve as essential components in pharmaceutical, biotech, and research applications, supporting the development and production of medicines, diagnostics, and other biologically active substances. Its onsite analytical testing capabilities include multi-compendial and custom specifications with full traceability and transparency of all raw materials and sources, operating from its FDA registered & inspected GMP manufacturing space under the most rigorous quality system.
Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
Sisco Research Laboratories Pvt. Ltd., established in 1975, is an Indian manufacturer and supplier of chemicals, biochemicals, and reagents, headquartered in Mumbai, Maharashtra. Supported by Food and Drug Administration (FDA)-approved manufacturing facilities, the company offers a range of products, including general laboratory chemicals and solvents, biochemical, bioreagents, and specialty fine chemicals. Their offerings also include animal cell culture, BioLit™ range of DNA and protein tools, and nanotechnology products. Additionally, SRL provides dehydrated culture media, biological ingredients, media supplements, chromogenic media, and media kits. These products serve diverse industries such as biotechnology, confectionary and food, personal care products, pharmaceuticals, and protein purification.
Biosynth International Inc. is a supplier of critical raw materials and services. The company was founded in 1966 with headquarters in Sraad, Switzerland. Biosynth has a global manufacturing and distribution network that supplies critical raw materials to the pharmaceutical and diagnostic industries across Europe, America, and Asia with local offices in the USA, China, the UK, Switzerland, Slovakia, and India. The company specializes in carbohydrates, nucleosides, peptides, neo-antigens, and enzyme substrates.
Nacalai Tesque Inc., founded in 1846 and headquartered in Kyoto, Japan, is a manufacturer of research chemicals, fine chemicals, diagnostics, and the related instruments. Some of its products include cytokines, nucleic acid electrophoresis, cell dissociation reagents, and sialic acid-related products, and it also offers custom and bulk service for bulk reagents and cell culture media. The company has more than 50 domestic distributors and several worldwide, including Asia, the Middle East, Oceania, Europe, and Africa. It is ISO 9001 and ISO 9002 certified, while the Kyoto South brand and Tesque factory are ISO 14001 certified.
Alfa Aesar is based in Lancashire, United Kingdom. Alfa Aesar is part of Thermo Fisher Scientific, is a manufacturer and supplier of chemicals, metals, and life science products for research and development. Alfa Aesar’s product lines include chemicals, life science, materials & metals, catalysts, and analytical & lab ware. Chemical offerings include inorganic compounds, organic compounds, organometallic, and solvents. Life sciences include biotechnology products, cellular & molecular biology, genomics, and immunology. Materials & metal include alloys, carbon, etchants, and more. Catalysts include ferrocenes, fuel cell products, and precious metals & catalysts. Alfa Aesar also offers custom manufacturing options.
Nacalai Tesque Inc. is a Japanese biotechnology company that specializes in the production and distribution of research reagents and diagnostic kits. Founded in 1958, Nacalai Tesque has grown into a globally recognized brand, serving customers in over 100 countries. The company's product portfolio includes antibodies, biochemicals, cell culture reagents, and more. Nacalai Tesque also offers contract research services for drug discovery and development. With a team of experienced professionals and state-of-the-art facilities, the company is committed to providing its customers with reliable and innovative solutions to their research needs.
Founded in Mumbai, India in 2006, Otto Chemie Pvt. Ltd. is an ISO 9001:2015 & GMP certified chemical manufacturing company and distributor. Otto Chemie serves customers in many industries including agriculture and food processing, pharmaceuticals, oil & gas, cement, as well as educational and R&D industries. Product offerings include antibiotics, amino acids, vitamins, detergents, ionic liquids, materials science compounds, labware, oil, metal & ceramic science compounds and tools, oils, reagents, solvents.
Ranking as of November 2024
Derivation MethodRank | Company | Click Share |
---|---|---|
1 | Otto Chemie Pvt. Ltd |
33.3%
|
2 | Nacalai Tesque Inc. |
11.1%
|
3 | MP Biomedicals |
11.1%
|
4 | Cayman Chemical Company |
11.1%
|
5 | Biosynth International, Inc. |
11.1%
|
6 | Alfa Aesar, Thermo Fisher Scientific. |
11.1%
|
7 | nacalai |
11.1%
|
Derivation Method
The ranking is calculated based on the click share within the dextran sulfate sodium page as of November 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
Country | Number of Companies | Share (%) |
---|---|---|
United States of America | 4 | 40.0% |
Japan | 3 | 30.0% |
India | 2 | 20.0% |
United Kingdom | 1 | 10.0% |