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This section provides an overview for thiophenol as well as their applications and principles. Also, please take a look at the list of 31 thiophenol manufacturers and their company rankings. Here are the top-ranked thiophenol companies as of December, 2024: 1.Sanjay Chemicals, 2.VIO Chemicals, 3.Nandadeep Chemicals Pvt. Ltd..
Table of Contents
Thiophenol, also known as benzenethiol, phenyl mercaptan, or mercaptobenzene, is a liquid where one hydrogen on the benzene ring is replaced by a thiol group (-SH). It is clear, colorless, or pale yellow, and has a characteristic rotten egg odor. Thiophenol is insoluble in water but soluble in ethanol and acetone. As a toxic substance, it requires careful handling due to its potential to irritate the eyes and skin.
Thiophenol is used in pharmaceuticals and agrochemicals, as an organic synthetic intermediate, anti-polymerization agent, antioxidant, and in photosynthesis research. Specific applications include:
Its thiol group functions as a nucleophile, useful for deprotecting protective groups, such as the nosyl (Ns) group in amines.
As a leaving group, thiophenol is involved in glycosylation reactions, where its removal is enhanced by N-iodosuccinimide (NIS) and trifluoromethanesulfonic acid (TfOH), facilitating the linking of different compounds.
Thiophenol, being highly acidic, serves as a source of electrons and protons in photosynthesis research.
It has a characteristic odor and should be used in a draft. Odor can be eliminated with hypochlorous acid. Thiophenol is more prone to deprotonation than phenol and decomposes easily under light, acid, or heat, producing harmful gases. It's advised to store it shielded from light and in an inert gas.
Thiophenol is synthesized mainly by the Freunderberg-Schonberg reaction, where phenol is thiocarbamated or thiocarbonated, and then converted to thiophenol. In industrial products, carbon disulfide is sometimes added to reduce the flash point.
*Including some distributors, etc.
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Spectrum Chemical MFG Corp. was founded in 1971, is headquartered in New Brunswick, New Jersey, and has facilities in Gardena, California. Spectrum is a fine chemical manufacturing company with an emphasis on USP, NF, FCC, BP, EP, JP, and ACS grade products, and is ISO 9001:2015 certified. Spectrum primarily serves the analytical, biopharmaceutical, food & beverage, personal care, and pharmaceutical chemicals industries. Spectrum has 4 product segments which are chemicals, equipment, supplies, and safety.
Parchem was founded in 1999 and headquartered in Rochelle, New York. Parchem is a distributor of industrial chemicals. Parchem serves nutritional, personal care, pharmaceutical, and specialty chemical industries. Parchem offerings include coatings, adhesives, elastomers, industrial products, petrochemicals, oleochemicals, plastics, rubber, nutritional supplements, cosmetics, consumer products, catalysts, metallic salts, rare earths, flavors & fragrances, industrial & institutional, textiles, other food-related chemicals, dyes, finishes, chemicals for aerospace, oil gas drilling chemicals, electronics, and pharmaceuticals.
TCI America (TCI) was founded in 1946 and is a worldwide manufacturer of specialty organic chemicals. The company produces organic laboratory chemicals as well as pharmaceutical, cosmetic, and functional materials. TCI’s product segments include Chemistry, Life Science, Materials Science, Analytical Chemistry, and Custom & Bulk. For materials science, the company manufactures battery materials, nanocarbon materials, and magnetic materials. For life sciences, the company produces antibodies, reagents, and chemicals for cancer research. The company produces HLC, NMR, various chemicals, and resins and media for analytical chemistry.
Pharmaffiliates, established in 2001 and located in Gurgaon, India, is a manufacturer of pharmaceutical standards and services. The company provides Certified Reference Standards (CRS) used in analytical methods, as well as drug delivery systems like tablets, capsules, injectables, and deuterated compounds that aid in research and development, studying drug metabolism and pharmacokinetics. Pharmaffiliates also offers various services to the pharmaceutical industry, including custom synthesis, analytical research, stability studies, and formulation development.
Shilpa Chemspec International Pvt. Ltd, established in 1982, is a manufacturer and wholesale trader of specialty chemicals and intermediates. This private company is based in Mumbai, India, and serves local and global clients. They distribute, import, and export specialty chemicals, papers, and boards, laminates, and coated foils. Their self-adhesive labels are used in various industries, including food and beverage, health and personal care, car, motor oil, and tyre. The company has recently ventured into contract manufacturing of intermediates used in bulk drugs, dyes, agrochemicals, and metal surface treatment chemicals.
Nandadeep Chemicals Pvt. Ltd. was founded in 1997 in Mumbai, India, and is a manufacturer of specialty chemicals such as Aryl sulfonic acids and salts for the following industries: cosmetics, pharmaceuticals, foundry, and surfactants. Besides manufacturing and exporting Para toluene sulfonic acid, the company also supplies grades of Sodium cumene sulfonate, Xylene sulfonic acid, Sodium toluene sulfonate, and Phenol sulfonic acid solutions. The products are made in compliance with the ISO 9001:2015 standards.
Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
Junsei Chemical Co. Ltd., established in 1948 and headquartered in Tokyo, Japan, is a manufacturer of chemical reagents and chemical products, including commissioned synthesis of chemical products. Some of the products it makes include Sodium chloride solution, concentrated glycerin, calcium chloride, ascorbic acid, and nitric acid. The chemical products have a wide range of applications and can be used in pathological examination, as food additives, for analysis, and in the pharmaceutical industry. All its plants, including its research institute, are ISO4001 and ISO9001 certified, while its Saitama and Ibaraki plants are equipped with buildings that comply with GMP.
Emco Dyestuff Pvt. Ltd., established in 1980 with headquarters in India, is a manufacturer of intermediates, industrial chemicals, solvents, and specialty chemicals used in various industries, including agrochemicals, electronics, and pharmaceuticals. Some of the company's products are ethylhexanoic acid, sodium sulfate anhydrous, Toluene Diisocyanate, and monoethylamine. The company is partnered with a number of companies, including OpenSpace Services, a manufacturer of specialty chemicals; Emco Engineering, a manufacturer of pharmaceutical machines; and Kosha Chemtech Pvt. Ltd., a software and IT support company providing simplified outsourcing solutions.
Toronto Research Chemicals Inc., founded in 1982 and based in Toronto, Canada, is a manufacturer of biochemicals and is a subsidiary of LGC Standards. The ISO 9001-certified company has an extensive catalog of over 350,000 products, including metabolites, impurities, and natural products APIs, which are used in several applications like environmental analysis, forensic science, and medicinal R&D. The company supports the scientific community across more than 120 countries and has 19 production laboratories. In 2019, it was bought by LGC, which provides components to customers in the pharmaceutical, clinical diagnostics, and food markets, among others.
RX MARINE INTERNATIONAL., founded in Mumbai, India, in 1996 is a manufacturer of chemical products for the marine industry. The company's product portfolio includes anti-corrosion coatings, water treatment solutions, fuel additives and tank coatings and linings that provide robust protection against aggressive cargo and ensure the integrity of cargo containment during maritime transport. Their products are used in industries such as transportation, Pharmaceutical and Biotechnology, Chemical and Petrochemical, Environmental Testing and yachting.
Sumitomo Seika Chemicals Co. LTD., founded in 1944 and headquartered in Osaka, Japan, is a manufacturer of functional chemicals, water-absorbing resins, and specialty gases. Some of its products include Aqua Keep, a super-absorbent resin produced using polymerization technology, and Aqua Coke, a nonionic polyalkylene oxide-based resin with water-absorbent properties. These resins find applications in various areas, such as in disposable diapers and as coagulants for wastewater treatment. The company was initially established for the production and sale of fertilizer. However, in 1981, it embarked on an expansion into functional resins, chemicals, and electronic gas businesses.
Merck, started in 1668 and based in Darmstadt, Germany, is a supplier of solutions and services for research, development, and manufacture of pharmaceutical and biotechnological drug therapies. The company serves the life science industry and has a broad portfolio of 300,000 products, including biopharmaceutical manufacturing, industrial microbiology, reagent, life science research, and water purification products. It is available in 66 countries, brings together six brands, and has several ISO certifications, including ISO 13485, ISO 14001, ISO 13485, and ISO 50001.
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
Nippon Sheet Glass Co., Ltd., established in 1918 and headquartered in Osaka, Japan, is a manufacturer and distributor of glass and glazing systems. The company offers a diverse range of products, including solar control glass, thermal insulation glass, safety and security glazing, glass for solar energy, and glass cords for automotive engine belts. These products find applications across multiple industries, serving the architectural, automotive, technical, electronics, and design and construction sectors. The company also serves as a supplier to companies like MICROGLAS, GLASFLAKE, and METASHINE.
Nacalai Tesque Inc., founded in 1846 and headquartered in Kyoto, Japan, is a manufacturer of research chemicals, fine chemicals, diagnostics, and the related instruments. Some of its products include cytokines, nucleic acid electrophoresis, cell dissociation reagents, and sialic acid-related products, and it also offers custom and bulk service for bulk reagents and cell culture media. The company has more than 50 domestic distributors and several worldwide, including Asia, the Middle East, Oceania, Europe, and Africa. It is ISO 9001 and ISO 9002 certified, while the Kyoto South brand and Tesque factory are ISO 14001 certified.
Alfa Aesar is based in Lancashire, United Kingdom. Alfa Aesar is part of Thermo Fisher Scientific, is a manufacturer and supplier of chemicals, metals, and life science products for research and development. Alfa Aesar’s product lines include chemicals, life science, materials & metals, catalysts, and analytical & lab ware. Chemical offerings include inorganic compounds, organic compounds, organometallic, and solvents. Life sciences include biotechnology products, cellular & molecular biology, genomics, and immunology. Materials & metal include alloys, carbon, etchants, and more. Catalysts include ferrocenes, fuel cell products, and precious metals & catalysts. Alfa Aesar also offers custom manufacturing options.
Jigs Chemical was established in 1998 and is based in India with global offices in the USA, UK, Canada, and Australia. Jigs Chemical is a manufacturer, distributor, and marketing & sales provider for organizations in India, specializing in chemicals and active pharmaceutical ingredients for pharmaceutical, agriculture, ceramics, metal treatment, and other industries. Jigs Chemical helps facilitate international customers to obtain chemicals from India, providing import and export assistance. Jigs Chemical’s product catalog includes over 40000 active pharmaceutical ingredients, commonly called APIs, their respective intermediates, and other chemicals.
Founded in 1981, Central Drug House Ltd. serves the scientific community via manufacturing and marketing a library of over 9,000 products to laboratory fine chemicals and dehydrated culture media with emphasis on purity and service. Examples are acids & bases, adsorbents, disinfectants, indicator papers, oils, and solvents. CDH provides bio chemicals, research chemicals, laboratory reagents, various solvents, stains & indicators, and dehydrated culture media. CDH is ISO 9001 certified and CDHs’ products are in compliance with specifications of IP, BP, USP, and EP standards.
Founded in Mumbai, India in 2006, Otto Chemie Pvt. Ltd. is an ISO 9001:2015 & GMP certified chemical manufacturing company and distributor. Otto Chemie serves customers in many industries including agriculture and food processing, pharmaceuticals, oil & gas, cement, as well as educational and R&D industries. Product offerings include antibiotics, amino acids, vitamins, detergents, ionic liquids, materials science compounds, labware, oil, metal & ceramic science compounds and tools, oils, reagents, solvents.
Fisher Scientific UK Ltd is a supplier of laboratory chemicals, equipment, and services based in Loughborough, United Kingdom, operating as a subsidiary of Thermo Fisher Scientific, a merger of Fisher Scientific International, Inc. and Thermo Electron in 2006. With a portfolio of over 2 million products, Fisher Scientific offers chemicals, reagents, equipment and instruments, consumables, and safety products. These products cater to various sectors, including clinical diagnostic and research laboratories, pharmaceutical and biotech industries, healthcare, and government agencies. Fisher Scientific also provides business solutions like the New-Lab Start-Up program, as well as SureTRACE and SureTRACE+ for product knowledge and supply chain management.
East India Chemicals (EIC) is an Indian supplier and distributor of industrial chemicals that was established in 2008. Based in Kolkata, the company primarily offers chemicals for use in marine applications, such as biocides, degreasers, antifouling agents, and oil spill dispersants. It also offers other industrial chemicals including surfactants and solvents, as well as specialty chemicals such as polymers, lubricants, and adhesives. EIC primarily serves clients in marine and wastewater operations, as well as in the rubber, textile, and agricultural industries.
India Fine Chemicals, founded in 1978 and headquartered in Taito-ku, Tokyo, Japan, is a distributor and supplier of chemicals, functional materials, food additives, as well as a planner and developer of health foods. The company offers an extensive range of products, including sodium vinylsulfonate 25% water solution, sodium cumene sulfonate, N-dimethyl-1,3-propanediamine, and diethyl sulfate. These chemicals serve various industries, including pharmaceuticals, agrochemicals, cosmetics, dyes, and flavors. The company also offers a range of services, including information about chemicals, a chemical search engine, product analysis, and contract development.
HAZMAT Resource, Inc., located in Irvine, California, USA, is a distributor of hazardous materials response equipment and materials. They specialize in personal protective equipment (PPE), testing devices, and technical reference materials for hazardous materials (hazmat) response. Their product range includes PPE such as suits, gloves, boots, and respirators to safeguard hazmat responders from dangerous substances. They offer various testing devices like meters, detectors, and kits for precise identification and measurement of hazardous materials. Additionally, the company provides technical reference materials like books, manuals, and software, equipping responders with essential knowledge on hazardous material properties and safe handling procedures.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | Sanjay Chemicals |
8.7%
|
| 2 | VIO Chemicals |
6.5%
|
| 3 | Nandadeep Chemicals Pvt. Ltd. |
6.5%
|
| 4 | Toronto Research Chemicals |
6.5%
|
| 5 | Junsei Chemical Co.,Ltd. |
6.5%
|
| 6 | nacalai |
6.5%
|
| 7 | Vision Pharma |
4.3%
|
| 8 | Stratechem Pvt. Ltd. |
4.3%
|
| 9 | Shilpa Chemspec International Pvt. Ltd. |
4.3%
|
| 10 | Jigs chemical |
4.3%
|
Derivation Method
The ranking is calculated based on the click share within the thiophenol page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
India
|
11 | 47.8% |
|
Japan
|
5 | 21.7% |
|
United States of America
|
2 | 8.7% |
|
United Kingdom
|
2 | 8.7% |
Switzerland
|
2 | 8.7% |
|
Canada
|
1 | 4.3% |
1 products found
1 products
SUMITOMO SEIKA CHEMICALS CO.,LTD.
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■ content ・ Benzen All ・ CAS No. 108-98-5 ■ Use ・ Pharmaceutical raw materials ・ Pesticide raw material ・ Organic synthetic intermediate raw ...
