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This section provides an overview for l-threonine as well as their applications and principles. Also, please take a look at the list of 22 l-threonine manufacturers and their company rankings. Here are the top-ranked l-threonine companies as of December, 2024: 1.MedChemExpress, 2.Venky’s, 3.Euro Asia Chemicals.
Table of Contents
Figure 1. Basic Information on L-Threonine
L-threonine, an essential amino acid, plays a critical role in protein synthesis in humans. It is a vital nutrient, sourced from dietary intake of eggs, chicken, skim milk, and gelatin, among others.
Beneficial for preventing fatty liver and regulating gastric acid, L-threonine supports skin moisture and hair health through collagen and keratin production. It is also crucial in animal feed to ensure nutritional balance.
Water-soluble, with a melting point of 256°C and notable for its biochemical roles, L-threonine's solubility and acid dissociation constants underline its biological significance.
Figure 2. Isomers of L-Threonine
Characterized by its polar, uncharged side chain and presence in human proteins, L-threonine's structural isomerism and optical activity are highlighted by its four possible isomers.
Figure 3. Biosynthesis of L-Threonine
While humans must obtain L-threonine through diet, plants, and microorganisms synthesize it from aspartic acid, following a multi-step biochemical pathway involving several enzymes.
L-threonine's metabolic pathways vary across species, contributing to vital processes such as glycine and acetyl CoA production in animals and playing a role in the biosynthesis of essential biomolecules like vitamin B12 in bacteria.
*Including some distributors, etc.
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MedChemExpress (MCE), is headquartered in Monmouth Junction, New Jersey, and is a supplier of research chemicals and biochemicals for laboratory and scientific use. The company’s product range includes biochemical assay reagents, isotope-labeled compounds, inhibitory antibodies, recombinant proteins, and fluorescent dyes. These products are used in various biopharmaceutical research and development fields, including areas such as infection, cardiovascular diseases, neurodegenerative diseases, diabetes, and autoimmune diseases. The company is ISO 19001 certified and provides testing services within the ISO 17025 framework, offering bulk and custom product services and support for metrological traceability.
GlpBio Technology, established in 2016 and headquartered in Montclair, California, is a supplier of life science products covering 20 popular research fields, including epigenetics, neuroscience, and cancer. Its product portfolio has over 20,000 life science reagents, including biochemicals, tag peptides, bioactive peptides, amino acids, and nature products. Its main clients include clinical diagnostic laboratories, government agencies, research institutes, universities, and pharmaceutical companies. The company regularly increases its products to meet the latest research needs and provides custom organic synthesis and analytical services.
Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
Kishida Chemical Co. Ltd., established in 1924 and headquartered in Osaka, Japan, is a manufacturer of reagents and high-purity chemicals and also does drug discovery support activities. Its product portfolio includes fine chemicals, research chemicals, ionic liquid, organic micro-analytical reagents, and chemical reagents for analysis. The products support several industries, including reagent business, battery material, drug discovery, and life science. The company is ISO 14001 certified and supplies several companies worldwide, including Meterion Advanced Chemicals Inc., Acros Organics, ChemBridge Corporation, Decon Laboratories, and InerBioScreen Ltd.
Venky's, Established in 1971, is a manufacturer of poultry solutions. With a blend of expertise and experience, the company expanded its operations to encompass SPF eggs, chicken and egg processing, broiler and layer breeding, genetic research, vaccine production, and more. Today, it stands as Asia's largest fully integrated poultry group, nurturing various esteemed organizations within its extensive scope, serving the poultry and related sectors. The VH Group's pioneering endeavors have earned it numerous national and international accolades.
SDA Products, founded in Mumbai, Maharashtra, in 1997 is a manufacturer and supplier of Veterinary Products. The company's product portfolio includes Bentonite Powder, Copper Sulphate Powder, Dextrose Monohydrate Powder, Ferrous Sulphate Crystals and Ferrous Sulphate Powder. Their products are used in industries such as Food and Beverage, Pharmaceutical and Biotechnology, Chemical and Petrochemical, Environmental Testing and healthcare. The company has a global distribution network, a customer support center, R&D center and quality control services.
Star Grace Mining Co., Ltd., established in 1990, has headquarters in China, and is a manufacturer of magnesium oxide, magnesium sulfate heptahydrate, and kieserite for customers worldwide. The company's products are used in many markets, including fertilizer, feeds, chemicals, textiles, and steelmaking markets, with an export capacity of 188,000 million tons per, mostly to Latin America, Southeast Asia, and Europe. Star Grace Mining Co., Ltd. holds ISO 9001, ISO 14001, and FAMI-QS certifications, as well as being a REACH-registered organization.
Shijiazhuang Jirong Pharmaceutical Co., Ltd. was established in 1993, with its headquarters in Shijiazhuang City, Hebei Province, as a GMP manufacturer of first-class amino acids, with 5,000MT annual capacity for APIs (pharma grade, EP, USP, etc) and another 20,000MT for exportation. Jirong Pharma has implemented a scientifically advanced management system that adheres fully to the Good Manufacturing Practice (GMP) standard. This assurance ensures superior product quality and service by maintaining rigorous control over the production process and quality assurance procedures.
PANGOO BIOTECH HEBEI CO., LTD. was established in 1993, with its headquarters in Cangzhou, China, as a manufacturer of feed additives in Amino Acids, Feed Protein, Vitamins, and Natural Materials such as soluble feed yeast, Soybean Meal, Corn Gluten Meal, Lysine, Bacillus subtilis, Choline Chloride, and DCP. The company has gained a significant market manifestation in various cities and provinces across China, owing to our extensive experience and robust technical support. Furthermore, it has successfully expanded its reach to international markets, serving clients in countries and regions including Germany, Norway, Poland, Finland, Spain, the United Kingdom, France, Russia, and the US.
Kyowa Hakko Bio Co., Ltd. was established in 2008 and is based in Tokyo, Japan, as a manufacturer of pharmaceutical raw materials and ingredients. It specializes in manufacturing bulk pharmaceuticals like citicoline, L-glutathione, and L-ornithine aspartate. It also manufactures raw materials for infusions, dietary supplements, and cosmetics, such as amino acids, peptides, oligosaccharides, and nucleic acids. The company is a subsidiary of Kirin Holdings Company and has obtained ISO 22000:2018, ISO/TS 22002-1:2009, and FSSC 22000 certifications. Its manufactured products are utilized in pharmaceuticals, nutritional supplements, industrial, and cosmetics sectors across Japan, China, the USA, Germany, and Italy.
Merck, started in 1668 and based in Darmstadt, Germany, is a supplier of solutions and services for research, development, and manufacture of pharmaceutical and biotechnological drug therapies. The company serves the life science industry and has a broad portfolio of 300,000 products, including biopharmaceutical manufacturing, industrial microbiology, reagent, life science research, and water purification products. It is available in 66 countries, brings together six brands, and has several ISO certifications, including ISO 13485, ISO 14001, ISO 13485, and ISO 50001.
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
Euro Asia Chemicals is a manufacturer that specializes in the production of cutting-edge chemicals serving various markets, including Surface Care, Fabric Care, Consumer Specialty, Industrial Specialty, and Health Care. The company leverages this knowledge base, introducing new products, and establishing itself as a global brand specializing in polymers for its target markets. These chemical products enhance the performance, appearance, and cost-effectiveness of products in Fabric Care, Hard Surface Care, Automotive, Personal Care, among many others.
NB Group Co. Ltd., founded in 1995, is a manufacturer and a high-tech enterprise in China. The company specializes in producing vitamins, amino acids, and food additives used in the pharmaceutical, animal husbandry, food, and other industries. Its focus is primarily on choline chloride, threonine, and vitamin B2, and it also engages in biotechnology research and development, running as many as 10 consecutive research projects at a time. The company's products are used extensively throughout China and exported to over 70 other countries.
Promois International was incorporated on 08 November, and its headquarters is in Kanpur, Uttar Pradesh, as a manufacturer of feed supplements of poultry feed like Choline Chloride, Toxin Binder, Chlortetracycline (CTC), Enzymes, and Acidifiers. Promois International has established itself as a global front-runner in the poultry feed business over the past two decades, specializing in providing high-grade chemical products. It employs many individuals globally through its own subsidiaries and joint ventures. Promois is at the forefront of assisting poultry feed millers in enhancing its feed formulation and producing various Halal poultry components.
Alfa Aesar is based in Lancashire, United Kingdom. Alfa Aesar is part of Thermo Fisher Scientific, is a manufacturer and supplier of chemicals, metals, and life science products for research and development. Alfa Aesar’s product lines include chemicals, life science, materials & metals, catalysts, and analytical & lab ware. Chemical offerings include inorganic compounds, organic compounds, organometallic, and solvents. Life sciences include biotechnology products, cellular & molecular biology, genomics, and immunology. Materials & metal include alloys, carbon, etchants, and more. Catalysts include ferrocenes, fuel cell products, and precious metals & catalysts. Alfa Aesar also offers custom manufacturing options.
ALPSURE LIFESCIENCES PVT. LTD., founded in Haryana, India, in 2015 is a manufacturer and distributor of Phytochemicals, Chemicals, Natural Herbal Extracts, and Organic Herbal Extracts. The company's product portfolio includes fruit Extracts Powders, Hadjod Cissus Quadrangularis Extracts, industrial chemicals, Nutraceuticals and dietary supplements and vitamin chemical powders. Their products are used in industries such as Food and Beverage, Pharmaceutical and Biotechnology, Chemical and Petrochemical, Agriculture and healthcare. The company has a global distribution network and a customer support center.
SWISS CHEMIE was established in 1958, and its headquarters is in Hertensteinstrasse, Luzern, Lucerne, Switzerland, as a manufacturer, supplier and exporter of livestock and poultry feed-grade products. The Swiss Chemie products are produced utilizing modern technology and methodologies within a facility that adheres to the standards of CGMP (Current Good Manufacturing Practices). All products are subjected to rigorous quality control tests to ensure compliance with regulatory standards regarding potency. Examples of the products include citrulline, glutamic, methionine, lysine, valine, alanine, and threonine.
BOC Sciences is headquartered in Shirley, New York as a brand of BOCSCI Inc. The company is a developer, manufacturer, marketer, and distributor of premium chemicals, emphasizing small molecule synthesis, biosynthesis, purification, and characterization used in academia, pharmaceuticals, biotech, CDMO, material sciences, and agriculture industries, supporting research and production. The company’s products include thousands of inhibitors, nucleotides, metabolites, and isotope-labeled products. The company offers custom synthesis and manufacturing, analytical services, antibody-drug conjugate development, and strain engineering and fermentation services.
Founded in 1981, Central Drug House Ltd. serves the scientific community via manufacturing and marketing a library of over 9,000 products to laboratory fine chemicals and dehydrated culture media with emphasis on purity and service. Examples are acids & bases, adsorbents, disinfectants, indicator papers, oils, and solvents. CDH provides bio chemicals, research chemicals, laboratory reagents, various solvents, stains & indicators, and dehydrated culture media. CDH is ISO 9001 certified and CDHs’ products are in compliance with specifications of IP, BP, USP, and EP standards.
National Analytical Corporation (NAC) is located in Mumbai, India. NAC was founded in 2009 as a distributor of laboratory grade chemicals used in numerous industries. NAC’s chemical offerings include biochemical & reagents such s Prunetin and 1,2-dipalmitoly-rac-glycerol, analytical grade chemicals such as chicoric acid and Vitamin E solutions, laboratory chemicals such as formic acid and nitric acid, gas chromatography chemicals such as Aalborg mass flowmeter battery kits and DEX 225, reference standard chemicals such as Palladium in HNO3, oral solid dosage forms, such as cellulosic and protect film coating systems, parenteral dosage forms, beverage & nutrition, and coating chemicals.
Foodchem was founded in 2006 in Shanghai, China. The company is ISO 9001 certified and is a producer, distributor, R&D provider, and marketer of specialty and standard food additives and ingredients to pharmaceutical, cosmetic, nutrition, and chemical industries around the world through distributors and self-managed warehouses. The company operates through four product segments: Food Ingredients, Feed Additives, Industrial Chemicals, and Active Pharmaceutical Ingredients. Certain categories include Kosher and Halal-certified products and products meeting other dietary restrictions.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | MedChemExpress |
15.5%
|
| 2 | Venky’s |
9.5%
|
| 3 | Euro Asia Chemicals |
7.1%
|
| 4 | Merck |
7.1%
|
| 5 | ALPSPURE LIFESCIENCES PRIVATE LIMITED |
6.0%
|
| 6 | Promois International |
6.0%
|
| 7 | NB GROUP CO., LTD, |
4.8%
|
| 8 | SDA Products |
3.6%
|
| 9 | Shijiazhuang Jirong Pharmaceutical Co., Ltd. |
3.6%
|
| 10 | PANGOO BIOTECH HEBEI CO., LTD. |
3.6%
|
Derivation Method
The ranking is calculated based on the click share within the l-threonine page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
India
|
6 | 37.5% |
|
China
|
4 | 25.0% |
|
Japan
|
3 | 18.8% |
|
United States of America
|
2 | 12.5% |
|
United Kingdom
|
1 | 6.3% |
