This section provides an overview for dibutylamine as well as their applications and principles. Also, please take a look at the list of 29 dibutylamine manufacturers and their company rankings. Here are the top-ranked dibutylamine companies as of November, 2024: 1.Tokyo Chemical Industry Co., Ltd., 2.First Continental International, 3.Pharmaffiliates.
Table of Contents
Dibutylamine, a clear, colorless liquid, is a secondary amine widely recognized in the chemical industry. It is officially named N-butylbutan-1-amine, with alternative names including N-butyl-butanamine and di-n-butylamine.
This compound plays a crucial role in various applications such as rubber chemicals, corrosion inhibitors, surfactants, pharmaceuticals, agrochemicals, dyes, mineral flotation agents, and emulsifiers, highlighting its versatility in industrial usage.
In rubber manufacturing, dibutylamine serves as a vulcanization accelerator, a critical additive for enhancing rubber elasticity through sulfur bonding. This process significantly improves the production efficiency and quality of rubber products.
As a corrosion inhibitor, dibutylamine protects metals from corrosion, especially in acidic environments. It forms a protective ammonium ion layer on the metal surface, demonstrating its effectiveness in corrosion prevention.
Dibutylamine (C8H19N) has a molecular weight of 129.24 and is identified by the CAS number 111-92-2. It remains liquid at room temperature, with a boiling point of 160°C and a flash point of 52°C. Its density ranges from 0.756 to 0.761 g/ml at 20°C, and it emits an ammonia-like odor. Notably, dibutylamine is soluble in alcohol, ether, water, and acetone, and is characterized by its flammable and highly corrosive properties.
The compound's pH level of 11.5 and a pKa of 11.31 for its conjugated acids indicate its basic nature and acid strength, respectively.
Dibutylamine can be synthesized through two primary methods: either by reacting ammonia with butanol or butyl chloride in the presence of alumina or silica catalysts at high temperatures, or through the dehydrogenation of ammonia, butanol, and hydrogen under a catalyst.
Regulated under various safety and environmental laws, dibutylamine is classified according to its flammability and corrosive nature, underscoring the importance of adhering to legal standards in its handling and storage.
Handling precautions include avoiding contact with oxidizing agents and using protective gear. In case of fire, suitable extinguishing media such as water spray or foam should be used. For storage, dibutylamine should be kept in a cool, well-ventilated area away from light to prevent degradation.
*Including some distributors, etc.
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First Continental International, established in 1996 and based in New Jersey, United States, is a distributor of chemicals and raw materials. The company sources these materials from manufacturers in China and Asia and distributes them to companies worldwide. First Continental International is ISO 9001:2015 certified and provides local warehousing, packaging, and delivery services. The company sources over 800 hazardous chemicals used in various industries, including adhesives & sealants, paints, paper & pulp, plastics & packaging, and oil & refinery.
Thermo Fisher Scientific Inc., founded in 1956 and headquartered in Waltham, Massachusetts, is a manufacturer and supplier of life science solutions, analytical instruments, specialty diagnostics, laboratory products, and biopharma services. Through its brand names, including Invitrogen, Fisher Scientific, Patheon, Applied Biosystems, and Gibco, among others, the company provides a wide range of products, which include chromatography systems, thermal cyclers, automated cell counters, fermenters, and DNA polymerases. The company’s annual revenue is over 40 billion USD, and it serves several fields, including customers working in clinical diagnostic labs, research institutions, hospitals, government agencies, and pharmaceutical/biotech companies.
Molekula Group, established in 2000, is a chemical manufacturer and distributor based in Darlington, United Kingdom, supported by additional offices and warehouses in Germany, Italy, China, and the United States. The company operates two British subsidiaries, namely Scafell Organics Ltd, which manufactures fine organic chemicals, and Sherman Chemicals Ltd, which provides custom solutions across industries. The company adheres to ISO 9001:2015 standards and offers a diverse range of over 4,500 products. Their product portfolio includes analytical reagents, biochemicals, building blocks, organic and inorganic chemicals, as well as research organics and inorganics.
Santa Cruz Biotechnology, Inc., established in 1991 and headquartered in Dallas, Texas, is an American manufacturer and supplier specializing in biological products for medical research. Initially providing antibodies to the research community, they expanded their offerings to include gene silencers like siRNA and shRNA (plasmid and lentiviral), targeting all known mouse and human genes. Over time, Santa Cruz Biotechnology provides over 175,000 research biochemicals under the brand ChemCruz, including protein-interacting inhibitors, substrates, and activators, tailored for studying protein functions. The company offers monoclonal primary antibodies, designed for various mammalian and non-mammalian protein targets, along with corresponding binding secondary antibodies.
Parchem was founded in 1999 and headquartered in Rochelle, New York. Parchem is a distributor of industrial chemicals. Parchem serves nutritional, personal care, pharmaceutical, and specialty chemical industries. Parchem offerings include coatings, adhesives, elastomers, industrial products, petrochemicals, oleochemicals, plastics, rubber, nutritional supplements, cosmetics, consumer products, catalysts, metallic salts, rare earths, flavors & fragrances, industrial & institutional, textiles, other food-related chemicals, dyes, finishes, chemicals for aerospace, oil gas drilling chemicals, electronics, and pharmaceuticals.
Neuchem is a distributor of specialty chemicals and raw materials, founded in 1993, and headquartered in Sparks, Nevada, USA. Its product offerings include acids, alcohols, amines, esters, as well as glycols, and solvents. These products are used for various industrial applications such as coatings, adhesives, plastics, rubber, cosmetics, and pharmaceuticals. The company assumes material ownership at the foreign port, manages ocean freight, customs clearance, terminal storage, and final delivery across the USA and Canada, as well as handle packaging, order documents, shipment updates, and coordinate until final delivery.
Wego Chemical Group was founded in 1978 and headquartered in Great Neck, New York. WEGO is a full-service supplier and distributor of chemicals, minerals, and other raw materials to clients around the world. Markets and segments include agriculture & animal care, chemical & material manufacturing, construction & building materials, electronics, food & beverage, “household, industrial & institutional”, mining, oil & gas, personal care & pharmaceutical, paper & packaging, surface treatment, textiles, and water treatment.
Hefei TNJ Chemical Industry Co., Ltd, established in 2001, is headquartered in China. The company is a chemical manufacturer and supplier of chemicals to domestic Chinese and global consumers in four primary markets: chemicals, food, pharmaceuticals, and personal care. Chemicals include fine chemicals, agrochemicals, and other chemicals. Food includes agrochemicals, vitamins, amino acids, and food ingredients. Pharmaceuticals include specific chemicals such as Povidone iodine, Clotrimazole crystalline, and Lincomycin. The company also features a CAS databank for CAS-registered chemical compounds.
Biosynth is a Swiss manufacturer of life science reagents established in 1966 and headquartered in Staad. The company sources and manufactures biochemical products such as carbohydrates, nucleosides, and enzyme substrates, as well as various peptides and biologics. They also operate as a contract manufacturer offering custom synthesis and manufacturing services for their clients in the pharmaceutical, diagnostic, food, and agrochemical sectors. Biosynth has regional sales offices and specialized facilities in Europe and North America, including in the Netherlands, United Kingdom, and United States.
Pharmaffiliates, established in 2001 and located in Gurgaon, India, is a manufacturer of pharmaceutical standards and services. The company provides Certified Reference Standards (CRS) used in analytical methods, as well as drug delivery systems like tablets, capsules, injectables, and deuterated compounds that aid in research and development, studying drug metabolism and pharmacokinetics. Pharmaffiliates also offers various services to the pharmaceutical industry, including custom synthesis, analytical research, stability studies, and formulation development.
Key Organics Ltd, founded in 1973 and headquartered in Cypress, USA, is a manufacturer of chemical products for the pharmaceutical, agrochemical and biotechnology industries. The company is an international CRO specializing in synthetic organic chemistry, providing chemistry and analytical services, as well as BIONET products for the global Life Science industries. Its BIONET portfolio consists of over 300,000 intermediates, fragments, biochemicals, and building blocks, available in ex-stock and in >95% purity with same day dispatch. The company offers bespoke chemistry solutions, from the custom synthesis of a single compound to multiple and long-term FTE projects.
LGC Standards Ltd., established in 1842, is a global British manufacturer and supplier of reference standards, headquartered in Teddington, Middlesex, with offices in 20 countries worldwide. As a subsidiary of LGC Group, the United Kingdom’s National Measurement Institute, LGC Standards also serves as the Government Chemist, providing expert opinions based on independent chemical and bioanalytical measurements. Under the business unit LGC Industrial, the company offers industrial measurement tools. Additionally, their subsidiaries, including Toronto Research Chemicals Inc (TRC) of Canada, LGC Mikromol™, and Dr. Ehrenstorfer™ of Germany, develop research tools, standards for pharmaceutical quality control, and reference materials for food and environmental analysis.
Loba Chemie Pvt. Ltd. is a Mumbai-based manufacturer and supplier of laboratory and fine chemicals, catering to industries such as pharmaceuticals, food, research, hospitals, and universities since its establishment in 1975. Their product range includes pH indicators, biological stains, HPLC solvents, high purity acids, and tetrazolium salts and derivatives. These products serve various applications like pH testing, cell and tissue staining, chemical separation, and pharmaceutical manufacturing. The company has several certifications, such as ISO/IEC 17025:2017 and ISO 9001:2015.
Toronto Research Chemicals Inc., founded in 1982 and based in Toronto, Canada, is a manufacturer of biochemicals and is a subsidiary of LGC Standards. The ISO 9001-certified company has an extensive catalog of over 350,000 products, including metabolites, impurities, and natural products APIs, which are used in several applications like environmental analysis, forensic science, and medicinal R&D. The company supports the scientific community across more than 120 countries and has 19 production laboratories. In 2019, it was bought by LGC, which provides components to customers in the pharmaceutical, clinical diagnostics, and food markets, among others.
SimSon Pharma Limited, established in 2011 and headquartered in Mumbai, India, is a manufacturer and supplier of pharmaceutical reference materials. Their product range includes drug working standards, drug impurity standards, drug metabolites, and stable isotope labeled compounds. These provide a basis for comparison and validation, enabling pharmaceutical companies to produce safe and effective medications. The company's offerings serve specific purposes, such as calibrating analytical instruments and ensuring precise analytical results, identifying and quantifying impurities in drugs, understanding drug metabolism, and developing new drug therapies.
TCI America (TCI) was founded in 1946 and is a worldwide manufacturer of specialty organic chemicals. The company produces organic laboratory chemicals as well as pharmaceutical, cosmetic, and functional materials. TCI’s product segments include Chemistry, Life Science, Materials Science, Analytical Chemistry, and Custom & Bulk. For materials science, the company manufactures battery materials, nanocarbon materials, and magnetic materials. For life sciences, the company produces antibodies, reagents, and chemicals for cancer research. The company produces HLC, NMR, various chemicals, and resins and media for analytical chemistry.
BASF Corporation, established in 1986 as the North American affiliate of BASF SE, is a manufacturer of chemical products, headquarters in Florham Park, New Jersey. The company operates 11 divisions which specialize in six business segments, namely chemicals, materials (such as plastics and rubber), industrial solutions, surface technologies (including construction chemicals and coating solutions), nutrition (for human and animal), and agricultural solutions. BASF's products find extensive applications across diverse industries such as automotive and transportation, construction, consumer electronics, energy, and furniture. Additionally, the company serves the medical and pharmaceuticals, paints and coatings, power tools, pulp and paper, as well as textile industries.
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
HPC Standards GmbH, established in 1996, is a manufacturer and distributor of high-purity analytical standards for residue analysis, located in Germany. The company specializes in the manufacture of reference materials for pesticides, veterinary products, and their metabolites and stable isotope-labelled derivatives. They are ISO 9001 certified and accredited according to ISO 17034. Their products are tested according to international quality requirements and meet the highest industrial standards. They serve as a competent partner in the fields of food and environmental analysis with a wide range of products, including dyes, food-related chemicals, polycyclic aromatic hydrocarbons (PAHs), polychlorinated biphenyls (PCBs), and polymer additives.
KOEI CHEMICAL CO. LTD. established in 1917 and based in Tokyo, Japan, is a manufacturer and supplier specializing in the production of chemical products. The company's product portfolio includes ionic liquids, amines, formalin products, pyridines, and pyrazines. These chemicals are utilized in various sectors, including pharmaceuticals, agricultural chemicals, electronics, furniture manufacturing, and the paint and coatings industry. The company is ISO 9001 and ISO 14001 certified, and provides custom synthesis and technical support to its clients.
Merck Millipore, founded in 1954 and headquartered in Darmstadt, Germany, is a manufacturer, distributor, and supplier of life science products and services. Their diverse range of products finds applications in research, development, and manufacturing of biotechnological and pharmaceutical drug therapies. Some of their offerings include filters for removing contaminants from liquids and gases, chromatography columns for separating and analyzing complex mixtures, reagents used in various laboratory assays, antibodies for detecting and quantifying specific molecules, and cell culture media for growing and maintaining cells in culture. Their products and services are utilized significantly in the advancement of life sciences and drug development.
Founded in 1981, Central Drug House Ltd. serves the scientific community via manufacturing and marketing a library of over 9,000 products to laboratory fine chemicals and dehydrated culture media with emphasis on purity and service. Examples are acids & bases, adsorbents, disinfectants, indicator papers, oils, and solvents. CDH provides bio chemicals, research chemicals, laboratory reagents, various solvents, stains & indicators, and dehydrated culture media. CDH is ISO 9001 certified and CDHs’ products are in compliance with specifications of IP, BP, USP, and EP standards.
Kat-Chem Ltd, founded in Hungary, is a distributor of chemicals. The company's product portfolio includes Ascorbic Acid and Benzalkonium Chloride, which are vital components in multiple industries and applications and custom chemical solutions. Its products are used in drug formulation and manufacturing, the sanitation and disinfection industry, and the food and beverage sector. The company is ISO 9001 registered and is a member of an international trading network named INDISGROUP representing numerous foreign companies in Hungary.
Founded in Mumbai, India in 2006, Otto Chemie Pvt. Ltd. is an ISO 9001:2015 & GMP certified chemical manufacturing company and distributor. Otto Chemie serves customers in many industries including agriculture and food processing, pharmaceuticals, oil & gas, cement, as well as educational and R&D industries. Product offerings include antibiotics, amino acids, vitamins, detergents, ionic liquids, materials science compounds, labware, oil, metal & ceramic science compounds and tools, oils, reagents, solvents.
Ataman Kimya A. S (Ataman Chemicals LLC), founded in 1940 and based in Istanbul, Turkey, is a supplier of pharmaceuticals and chemical raw materials. Ataman Kimya A. S serves industries including agriculture, cosmetics, food additive, petroleum, among others with products such as disinfectants, cosmetics, metal and mining chemicals, textile and leather chemicals, paints, as well as industrial and pharmaceutical chemicals. The company holds the sales and marketing rights of Nordic Chemical Laboratories and is known for the enviromental care it provides.
ChemSrc, established in 2014, is a supplier of pharmaceutical products, a chemical database platform, and a search engine. This platform serves as a gateway to an extensive repository of chemical knowledge, offering access to unique CAS-encoded product records including synthesis routes, literature references, physical and chemical properties, and supplier information. The chemical catalog spans various categories, including organic raw materials, dyes and pigments, chemical pesticides, catalysts, additives, and more. The repository information plays a vital role in supporting research and development efforts across diverse industries by fostering scientific advancements and serving as a valuable resource.
Ranking as of November 2024
Derivation MethodRank | Company | Click Share |
---|---|---|
1 | Tokyo Chemical Industry Co., Ltd. |
17.6%
|
2 | First Continental International |
11.8%
|
3 | Pharmaffiliates |
11.8%
|
4 | Chongqing Apexmol Technology Co.,Ltd |
5.9%
|
5 | Guangzhou Howei Pharma Tech Co.,Ltd. |
5.9%
|
6 | Key Organics Ltd |
5.9%
|
7 | SimSon Pharma Limited |
5.9%
|
8 | Hefei TNJ Chemical Industry Co.,Ltd. |
5.9%
|
9 | Biosynth |
5.9%
|
10 | Molekula Americas LLC |
5.9%
|
Derivation Method
The ranking is calculated based on the click share within the dibutylamine page as of November 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
Country | Number of Companies | Share (%) |
---|---|---|
United States of America | 7 | 28.0% |
India | 5 | 20.0% |
China | 3 | 12.0% |
Switzerland | 2 | 8.0% |
United Kingdom | 2 | 8.0% |
Japan | 2 | 8.0% |
Canada | 1 | 4.0% |
Germany | 1 | 4.0% |
Hungary | 1 | 4.0% |
Turkey | 1 | 4.0% |