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This section provides an overview for p-cymene as well as their applications and principles. Also, please take a look at the list of 12 p-cymene manufacturers and their company rankings. Here are the top-ranked p-cymene companies as of December, 2024: 1.Cayman Chemical Company, 2.KANTO CHEMICAL CO.,INC., 3.GYAN FLAVOURS EXPORT PRIVATE LTD..
Table of Contents
p-Cymene is an organic compound in which two hydrogens of benzene are replaced by methyl and isopropyl groups.
Usually, p-Cymene (paracymene) has a structure in which a methyl group and an isopropyl group are substituted at the para-positions (1 and 4) of the benzene ring.
The CAS registration number is 99-87-6. However there are two positional isomers, o-cymene (CAS No. 527-84-4) and m-cymene (CAS No. 535-77-3), neither of which is found in nature.
In nature, p-Cymene is found in the essential oils of shell ginger, cumin, and thyme. It is commonly used as a fragrance and is used in soaps. The substance has a citrus odor with a volatile oil smell.
p-Cymene is a useful substance as an organic synthetic raw material. It is used as a raw material for the synthesis of terephthalic acid and thymol.
Among the intermediates and building blocks that can be synthesized from p-Cymene are p-Cymene hydroperoxide, 4-methylacetophenone, 4-isopropylbenzyl alcohol, 4-isopropylbenzaldehyde, and 4-isopropylbenzoic acid. These substances are sometimes used to study oxidation reactions under various conditions.
p-Cymene is an organic compound classified as a monoterpene (a 10-carbon hydrocarbon produced by plants, insects, fungi, and bacteria) and an aromatic hydrocarbon.
Its molecular formula is C10H14 and its molecular weight is 134.22. It has a melting point of -68.9°C, a boiling point of 177.10°C, and is a clear, colorless liquid at room temperature.
It has a characteristic aroma, sometimes described as citrusy, reminiscent of lemon. It is miscible with ethanol, acetone, benzene, carbon tetrachloride, and petroleum ether, but is virtually insoluble in water. It has a density of 0.857 g/mL.
Although p-Cymene is stable under normal handling conditions, it reacts with oxidizing agents and is believed to attack rubber. During storage, it is necessary to avoid mixing with these substances. p-Cymene is also used as a ligand for ruthenium. A typical example is dichloro(p-Cymene)ruthenium(II) (η6-cymene)2Ru2Cl4), which is usually sold in dimer form (CAS registration number 52462-29-0).
This complex is synthesized from ruthenium trichloride and α-ferlandrene and is used as a precursor to various ruthenium-cymene complexes. Other p-Cymene complexes of osmium are also known.
p-Cymene is commonly sold as an industrial raw material substance in reagent products for research and development and in fragrances. As mentioned above, p-Cymene is the most common.
p-Cymene is available as an R&D reagent product in a variety of capacities, including 25 mg, 25 mL, 500 mL, 1 kg, 8 kg, and 20 kg. Typically, these reagent products can be handled at room temperature.
Some reagent manufacturers offer o-Cymene and m-Cymene, but in small quantities of only a few hundred milligrams, and the price is also effective. As an industrial raw material, it is offered in units of 100 g, 1 kg, 25 kg, etc., and may also be customized to meet other demands.
p-Cymene is industrially produced by dehydrogenation of α-pinene with iodine (I2) or phosphorus trichloride (PCl3) or by the Friedel-Crafts alkylation reaction of toluene and propene.
*Including some distributors, etc.
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Cayman Chemical Company is a manufacturer of life science research products founded in 1979 in Ann Arbor, Michigan, USA. They offer a diverse array of analytical standards, reagents, and other products for research in cancer, oxidative injury, epigenetics, neuroscience, inflammation, as well as metabolism, and other areas. The company supplies small molecules, biochemicals, assay kits, antibodies, and proteins to research scientists across academic, biotechnology, and pharmaceutical institutions. Cayman Chemical Company holds dual accreditations to ISO/IEC 17025:2017 and ISO 17034:2016 by ANAB Accreditation Services.
Santa Cruz Biotechnology, Inc., established in 1991 and headquartered in Dallas, Texas, is an American manufacturer and supplier specializing in biological products for medical research. Initially providing antibodies to the research community, they expanded their offerings to include gene silencers like siRNA and shRNA (plasmid and lentiviral), targeting all known mouse and human genes. Over time, Santa Cruz Biotechnology provides over 175,000 research biochemicals under the brand ChemCruz, including protein-interacting inhibitors, substrates, and activators, tailored for studying protein functions. The company offers monoclonal primary antibodies, designed for various mammalian and non-mammalian protein targets, along with corresponding binding secondary antibodies.
Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
Gyan Flavours Export, a manufacturer, operates with a Research and Development department, ensuring stringent international quality control standards. The company engages in extensive research on various Natural Terpenes, Essential Oils, and Aroma Chemicals. Its state-of-the-art facility, fully computerized with Chromatograph and Pilot Distillation Columns, adheres to the latest production methods. The company, known for its product quality, serves both the domestic and international markets by offering a wide range of products. Prioritizes customer satisfaction and provides tailored solutions to meet the demands of both local and global markets.
Indian Spice Oil Industries is a manufacturer of natural essential oils, known for producing quality, pure, and effective products. The company serves various industries such as food processing, perfume manufacturing, cosmetics, pharmaceuticals, and spa and aromatherapy centers. Maintaining constant quality checks to deliver natural products, the product range includes Natural Spice Oils, Natural Essential Oils, and Natural Isolates, catering to diverse applications, and expanding the product range to include more options. These oils find use in various applications, from relaxation to medicinal purposes.
Natural Aroma Products Pvt. Ltd. is a manufacturer, wholesaler, trader, and exporter of aromatic products, established in 1995 and based in Delhi, India. The company produces solutions for the production of various items in industries such as perfumes, medicines, aromatherapy, food processing, as well as personal hygiene products and cosmetics. Its product offerings include essential oils such as Ajowain Oil and Basil Oil, aroma chemicals such as D-Limonene, natural isolates, and reconstituted oils.
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
Alfa Aesar is based in Lancashire, United Kingdom. Alfa Aesar is part of Thermo Fisher Scientific, is a manufacturer and supplier of chemicals, metals, and life science products for research and development. Alfa Aesar’s product lines include chemicals, life science, materials & metals, catalysts, and analytical & lab ware. Chemical offerings include inorganic compounds, organic compounds, organometallic, and solvents. Life sciences include biotechnology products, cellular & molecular biology, genomics, and immunology. Materials & metal include alloys, carbon, etchants, and more. Catalysts include ferrocenes, fuel cell products, and precious metals & catalysts. Alfa Aesar also offers custom manufacturing options.
NIPPON TERPENE CHEMICALS, INC. established in 1919 and located in Kobe, Hyogo, Japan, is a manufacturer and distributor of Terpene-based chemicals. The company's product range includes industrial solvents, aroma chemicals, active pharmaceutical ingredients, polyfunctional alcohols, and chain-transfer agents for RAFT polymerization. Industrial solvents are applied in electronic materials, while aroma chemicals are used in fragrances and as food additives. Pharmaceuticals are compliant with the Japanese Pharmacopoeia. Additionally, they provide solutions in RAFT polymerization. The primary industries it serves include electronics, fragrance, food, and pharmaceuticals.
Founded in 1981, Central Drug House Ltd. serves the scientific community via manufacturing and marketing a library of over 9,000 products to laboratory fine chemicals and dehydrated culture media with emphasis on purity and service. Examples are acids & bases, adsorbents, disinfectants, indicator papers, oils, and solvents. CDH provides bio chemicals, research chemicals, laboratory reagents, various solvents, stains & indicators, and dehydrated culture media. CDH is ISO 9001 certified and CDHs’ products are in compliance with specifications of IP, BP, USP, and EP standards.
Odowell is a Chinese company that specializes in the production and distribution of health wellness products. Established in 2004, the main products include blood glucose meters, blood pressure monitors, and infrared thermometers. ODOWELL provides affordable healthcare solutions to customers worldwide. With research and development, the company has earned a reputation for innovation and reliability in the healthcare industry. ODOWELL's customer satisfaction and its dedication to improving healthcare globally make it a reputable brand.
Founded in Mumbai, India in 2006, Otto Chemie Pvt. Ltd. is an ISO 9001:2015 & GMP certified chemical manufacturing company and distributor. Otto Chemie serves customers in many industries including agriculture and food processing, pharmaceuticals, oil & gas, cement, as well as educational and R&D industries. Product offerings include antibiotics, amino acids, vitamins, detergents, ionic liquids, materials science compounds, labware, oil, metal & ceramic science compounds and tools, oils, reagents, solvents.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | Cayman Chemical Company |
31.6%
|
| 2 | KANTO CHEMICAL CO.,INC. |
15.8%
|
| 3 | GYAN FLAVOURS EXPORT PRIVATE LTD. |
5.3%
|
| 4 | Indian Spice Oil Industries |
5.3%
|
| 5 | NATURAL AROMA PRODUCTS PVT. LTD. |
5.3%
|
| 6 | KUNSHAN ODOWELL CO.,LTD |
5.3%
|
| 7 | Central Drug House |
5.3%
|
| 8 | Otto Chemie Pvt. Ltd |
5.3%
|
| 9 | Alfa Aesar, Thermo Fisher Scientific. |
5.3%
|
| 10 | Santa Cruz Biotechnology, Inc. |
5.3%
|
Derivation Method
The ranking is calculated based on the click share within the p-cymene page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
India
|
5 | 50.0% |
|
United States of America
|
2 | 20.0% |
|
Japan
|
1 | 10.0% |
|
United Kingdom
|
1 | 10.0% |
|
China
|
1 | 10.0% |
