12 Quinoline Manufacturers in 2024
This section provides an overview for quinoline as well as their applications and principles. Also, please take a look at the list of 12 quinoline manufacturers and their company rankings. Here are the top-ranked quinoline companies as of November, 2024: 1.Vigon International, 2.Nacalai USA, Inc., 3.ChemUniverse, Inc..
Table of Contents
What Is Quinoline?
Quinoline is an organic compound belonging to the heterocyclic aromatic family. Its chemical formula is C9H7N.
Quinoline has a fused ring structure of a benzene ring and a pyridine ring. It is also known as 1-azanaphthalene, 1-benzazine, benzo[b]pyridine, etc. Its CAS registration number is 91-22-5.
It has a molecular weight of 129.16, a melting point of -15°C, and a boiling point of 238°C. At room temperature, it is a colorless, hygroscopic liquid substance. It has a strong odor. Its density is 1.09 g/mL and the pKa of the conjugated acid is 4.85.
Although only slightly soluble in water, it is extremely soluble in ethanol and diethyl ether. In natural products, it is found in coal tar.
Uses of Quinoline
The main uses of quinoline are as a synthetic raw material for dyes, agrochemicals, pharmaceuticals, and polymers, as a reagent for the determination of metal ions, and as a solvent.
Quinoline has the property of forming salts with specific metal ions such as Fe3+ and Zn2+ in solution. This property makes it possible to use quinoline as a reagent for quantitative determination of metal ions.
Quinoline is also used as a raw material for pharmaceutical synthesis in the preparation of niacin, 8-hydroxyquinoline, quinine, and others. In addition, quinoline is used in a variety of other fields, such as in the production of quinoline dyes, as a preservative, and as a disinfectant.
Properties of Quinoline
1. Synthesis of Quinoline
Several synthetic routes have been reported for quinolines, including the Combes quinoline synthesis, in which an imine is prepared from aniline and a 1,3-diketone, followed by cyclization of the product intermediate with an acid. The Conrad-Limpach synthesis is a condensation of anilines with β-ketoesters.
Skraup synthesis is another well-known synthetic method, in which anilines are synthesized from glycerol and nitrobenzene in the presence of sulfuric acid.
Glycerin Is Dehydrated By Acid To Form Acrolein.
The aza-Michael addition of aniline to the acrolein to form β-aminoaldehyde. The Intramolecular Friedel-Crafts reaction proceeds to the carbonyl group. Dehydration of the intermediate leads to the formation of 1,2-dihydroquinoline, and dehydrogenation occurs with nitrobenzene acting as an oxidant
2. Chemical Properties of Quinoline
Quinoline is a substance that can be altered by light. If stored for a long period of time in an area exposed to light, quinoline will turn yellow, and if left unattended, will turn brown.
When storing, avoid high temperatures, direct sunlight, heat, flames, and static sparks. Mixture with strong oxidizers should also be avoided. Hazardous decomposition products include carbon monoxide, carbon dioxide, and nitrogen oxides.
Types of Quinolines
Quinoline is sold primarily as a reagent product for research and development. The types of volumes include 1mL, 25mL, 500mL, 3L, and 25g. It is offered in volumes that are easy to use in the laboratory. These reagent products can be stored at room temperature.
It is a chemical used as a solvent as well as a raw material for organic synthesis and for the quantitative determination of metal ions as mentioned above.
Other Information on Quinoline
Quinoline Toxicity Information
Quinoline is a toxic substance. Specific hazards include skin irritation, strong eye irritation, suspected hereditary disease, carcinogenesis, and respiratory tract irritation.
List of 12 Quinoline Manufacturers
*Including some distributors, etc.
Sort by Features
- Default
- Company Size: largest first
- Year Founded: oldest first
- Year Founded: earliest first
Sort by Area
- United States of America
- Japan
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American Elements
Quinolines
Manufacturer Overview
American Elements was founded in 1997 in California and currently has research and production facilities in Utah, Mexico, China, and the United Kingdom. AE manufactures and distributes advanced materials from a catalog of over 30,000 products for bulk industrial use as well as small scale laboratory use. AE also provides testing and analyses services including spectroscopy along with structural, thermal, and electrical analyses. AE holds sustainable development as a core corporate value and is committed to work to protect the health of the environment.
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Vigon International
Quinoline
Manufacturer Overview
Vigon International is headquartered in East Stroudsburg, Pennsylvania, and is a subsidiary of Azelis. The company is a custom manufacturer of fragrances and flavor products used in cosmetics, food processing, and related industries. The company’s compounds originate from dozens of fruits, herbs, and spices grown in regions as diverse as California, Germany, Brazil, and Indonesia. The company’s custom processing capabilities include adding reaction flavors such as Maillard in batches from 1 to 5,000kg, vacuum distillations, essential oil folding and concentration, and emulsion production.
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SAE Manufacturing Specialties Corp
Quinoline
Manufacturer Overview
Based in Bayville, NY, SAE Manufacturing Specialties Corp. is an ISO-certified supplier and manufacturer of industrial equipment, chemicals, components, ordinance, electronics, and systems for industries ranging from aerospace to high tech to law enforcement. Examples of product offerings include raw materials, chemicals, and lubricants for industrial purposes to finished products such as security helmets for law enforcement, and military ordnances. SAE also provides research and development as well as technical support for other companies in similar industries.
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Nacalai USA, Inc.
COSMOSIL Quinoline
Company Overview
Nacalai USA Inc., founded in 2005, is a supplier and distributor of scientific research products and biochemicals based in California, USA. The company is a subsidiary of Nacalai Tesque Inc., headquartered in Kyoto, Japan, which specializes in providing biochemicals. The company offers a diverse portfolio of research reagents, chemicals, laboratory equipment, and scientific instruments to support various fields of scientific research. Some of the products provided include biochemicals, cell culture media, laboratory chemicals, chromatography columns, and molecular biology tools. The company's expertise lies in producing research-grade agarose gel electrophoresis products used in molecular biology laboratories for DNA and RNA analysis.
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Wego Chemical Group Inc
Quinoline
Distributor Overview
Wego Chemical Group was founded in 1978 and headquartered in Great Neck, New York. WEGO is a full-service supplier and distributor of chemicals, minerals, and other raw materials to clients around the world. Markets and segments include agriculture & animal care, chemical & material manufacturing, construction & building materials, electronics, food & beverage, “household, industrial & institutional”, mining, oil & gas, personal care & pharmaceutical, paper & packaging, surface treatment, textiles, and water treatment.
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ChemUniverse, Inc.
Quinoline
Distributor Overview
ChemUniverse, Inc. is a privately owned and operated specialty chemical provider that was founded in 2019.They are headquartered in Des Plaines, Illinois. They sell a wide range of chemicals, including amyl benzoate, naphthalene, pyridine, anethole, isoamyl benzoate, and many others which have different purposes. For instance, Amyl benzoate is a flavoring ingredient found in foods and perfumes while Naphthalene is a moth repellent and a component of various industrial solvents. They offer their services to customers looking for specialized or unique products and offer custom synthesis services to produce items that aren't already in their inventory.
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KANTO CHEMICAL CO.,INC.
Quinoline
Manufacturer Overview
Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
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Junsei Chemical Co.,Ltd.
Quinoline
Manufacturer Overview
Junsei Chemical Co. Ltd., established in 1948 and headquartered in Tokyo, Japan, is a manufacturer of chemical reagents and chemical products, including commissioned synthesis of chemical products. Some of the products it makes include Sodium chloride solution, concentrated glycerin, calcium chloride, ascorbic acid, and nitric acid. The chemical products have a wide range of applications and can be used in pathological examination, as food additives, for analysis, and in the pharmaceutical industry. All its plants, including its research institute, are ISO4001 and ISO9001 certified, while its Saitama and Ibaraki plants are equipped with buildings that comply with GMP.
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Merck
Quinoline
Manufacturer Overview
Merck, started in 1668 and based in Darmstadt, Germany, is a supplier of solutions and services for research, development, and manufacture of pharmaceutical and biotechnological drug therapies. The company serves the life science industry and has a broad portfolio of 300,000 products, including biopharmaceutical manufacturing, industrial microbiology, reagent, life science research, and water purification products. It is available in 66 countries, brings together six brands, and has several ISO certifications, including ISO 13485, ISO 14001, ISO 13485, and ISO 50001.
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MilliporeSigma
Quinoline
Manufacturer Overview
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
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Boron Molecular
Quinoline
Manufacturer Overview
Boron Molecular is a manufacturer and supplier of specialty chemicals such as agents, energy storage compounds, monomers and polymers. It was established in 2001 and is headquartered in Noble Park, Victoria, Australia. The company produces a wide range of specialty chemicals, including boron compounds, boronic acids, and organic building blocks. Its products, such as B2O3, H3BO3, tetrakis(hydroxymethyl) borate, 1,2-dihydroxy borate, and Yb3+-doped YAG laser crystal, are used by a number of industries, as diverse as pharmaceutical, chemical, and materials industries. Boron Molecular also provides a range of services, including custom synthesis, formulation, packaging, and logistics.
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nacalai
Quinoline
Company Overview
Nacalai Tesque Inc., founded in 1846 and headquartered in Kyoto, Japan, is a manufacturer of research chemicals, fine chemicals, diagnostics, and the related instruments. Some of its products include cytokines, nucleic acid electrophoresis, cell dissociation reagents, and sialic acid-related products, and it also offers custom and bulk service for bulk reagents and cell culture media. The company has more than 50 domestic distributors and several worldwide, including Asia, the Middle East, Oceania, Europe, and Africa. It is ISO 9001 and ISO 9002 certified, while the Kyoto South brand and Tesque factory are ISO 14001 certified.
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Quinoline Manufacturer Ranking
*Including some distributors, etc.Ranking as of November 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | Vigon International |
22.2%
|
| 2 | MilliporeSigma |
22.2%
|
| 3 | Nacalai USA, Inc. |
11.1%
|
| 4 | ChemUniverse, Inc. |
11.1%
|
| 5 | American Elements |
11.1%
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| 6 | SAE Manufacturing Specialties Corp |
11.1%
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| 7 | KANTO CHEMICAL CO.,INC. |
11.1%
|
Derivation Method
The ranking is calculated based on the click share within the quinoline page as of November 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
- KANTO CHEMICAL CO.,INC.: 1,062
- Junsei Chemical Co.,Ltd.: 171
Newly Established Company
- Nacalai USA, Inc.: 2005 (19 years ago)
- Boron Molecular: 2001 (23 years ago)
- Wego Chemical Group Inc: 1978 (46 years ago)
Company with a History
- nacalai: 1934 (90 years ago)
- KANTO CHEMICAL CO.,INC.: 1944 (80 years ago)
- Junsei Chemical Co.,Ltd.: 1948 (76 years ago)
Quinoline Manufacturers in United States
*Including some distributors, etc.
- American Elements
- Vigon International
- SAE Manufacturing Specialties Corp
- Nacalai USA, Inc.
- Wego Chemical Group Inc
- ChemUniverse, Inc.
Global Distribution of Quinoline Manufacturers by Country
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
United States of America
|
6 | 66.7% |
Japan
|
3 | 33.3% |
