All Categories
This section provides an overview for xanthone as well as their applications and principles. Also, please take a look at the list of 11 xanthone manufacturers and their company rankings. Here are the top-ranked xanthone companies as of December, 2024: 1.Sinco Pharmachem Inc., 2.GLPBIO Technology LLC.
Table of Contents
1993~2019: Engaged in pharmaceutical research and development and analysis of various biological samples at the Pharmaceutical Research Institute of Japan Kayaku Co., Ltd. He is also in charge of facility management as a dangerous goods handler and radiation handling chief.
2019: Moved to another company in the same industry and has been in charge of similar work until now.
He also writes, translates, and edits specialized books.
Linkedin: https://www.linkedin.com/in/makoto-niwa-25331040/
Researchmap: https://researchmap.jp/0000-0002-2355-1222/
Xanthone is an organic compound with the chemical formula C13H8O2 and a three-ring structure in which two benzene rings are bridged by an ether and a ketone.
Its CAS number is 90-47-1 and its other names include "genicid" and "benzophenone oxide." Xanthone can be synthesized by heating phenyl salicylate. It is also known to occur naturally in Harungana and Garcinia.
Xanthone has been used since 1939 as an insecticide, especially for the control of codling moth eggs and larvae. It is also the raw material for xanthidolol, which is used to measure urea levels in the blood. The reduction of xanthone yields xantidrol.
Xanthone has a specific gravity (density) of approximately 1.1607, a melting point of 173-177°C, and a boiling point of 349-350°C. It is almost insoluble in water. It is almost insoluble in water, insoluble in ethanol and ether, and soluble in chloroform.
It exists in solid form at room temperature and is white to light brown or light red. Under normal conditions, it is highly stable. However, because it is an organic compound, it is very dangerous when mixed with strong oxidizers. It is possible that it may be altered by light, so it should be shielded from light when stored.
Xanthone is orally toxic. It is classified as a poisonous or toxic substance under the Regulations on the Transport and Storage of Dangerous Goods by Ships and the Civil Aeronautics Law, and as a toxic solid (organic substance) under UN2811, the UN number related to transportation.
There is a group of xanthone derivatives called mangostin (α-mangostin and γ-mangostin), which have been suggested to have a variety of physiological effects, including antibacterial activity, anticancer activity, antioxidant activity, and anti-inflammatory effects. As the name suggests, these are found in the rind of the mangosteen plant.
These unique plant-derived chemicals are called phytochemicals. Many other xanthone derivatives and their glycosides are also known to be biologically active phytochemicals. Some of these are commercialized as supplements, such as mangosteen extract derived from the mangosteen plant.
Although the term "xanthones" is sometimes used to include all phytochemicals with the xanthone structure, they should be referred to as xanthones. They are sometimes called xanthonoids. It is important to note that these phytochemicals are not xanthones themselves.
Benzoyl coenzyme A is first produced from benzoic acid. In the raw material stage, there is one benzene ring derived from benzoic acid.
Three molecules of malonyl coenzyme A react with it to form 2,4,6-trihydroxybenzophenone. A new ring is formed using three molecules of malonyl coenzyme A, with a ketone group between the two rings.
Next, 2,3',4,6-tetrahydroxybenzophenone is formed by the action of benzophenone-3'-hydroxylase and cytochrome P450 monooxygenase. This is the state to which the hydroxyl group is added.
From this state, a third ring is formed by the action of xanthone synthase to form the xanthone structure. As shown in this example, most naturally occurring xanthonoids have hydroxyl groups, and only a few are pure xanthone.
*Including some distributors, etc.
Sort by Features
Sort by Area
GlpBio Technology, established in 2016 and headquartered in Montclair, California, is a supplier of life science products covering 20 popular research fields, including epigenetics, neuroscience, and cancer. Its product portfolio has over 20,000 life science reagents, including biochemicals, tag peptides, bioactive peptides, amino acids, and nature products. Its main clients include clinical diagnostic laboratories, government agencies, research institutes, universities, and pharmaceutical companies. The company regularly increases its products to meet the latest research needs and provides custom organic synthesis and analytical services.
Santa Cruz Biotechnology, Inc., established in 1991 and headquartered in Dallas, Texas, is an American manufacturer and supplier specializing in biological products for medical research. Initially providing antibodies to the research community, they expanded their offerings to include gene silencers like siRNA and shRNA (plasmid and lentiviral), targeting all known mouse and human genes. Over time, Santa Cruz Biotechnology provides over 175,000 research biochemicals under the brand ChemCruz, including protein-interacting inhibitors, substrates, and activators, tailored for studying protein functions. The company offers monoclonal primary antibodies, designed for various mammalian and non-mammalian protein targets, along with corresponding binding secondary antibodies.
Sinco Pharmachem, founded in 2005 and headquartered in Shanghai, China, is a manufacturer and supplier of pharmaceutical intermediates and fine chemicals. The company specializes in producing various complex and high-purity organic compounds. These products are used in industries such as pharmaceuticals, agrochemicals, universities, and science institutions. It is utilized in the synthesis of various medications and agrochemicals. The company follows API standards in its drug development to ensure safety and environmental protection.
Parchem was founded in 1999 and headquartered in Rochelle, New York. Parchem is a distributor of industrial chemicals. Parchem serves nutritional, personal care, pharmaceutical, and specialty chemical industries. Parchem offerings include coatings, adhesives, elastomers, industrial products, petrochemicals, oleochemicals, plastics, rubber, nutritional supplements, cosmetics, consumer products, catalysts, metallic salts, rare earths, flavors & fragrances, industrial & institutional, textiles, other food-related chemicals, dyes, finishes, chemicals for aerospace, oil gas drilling chemicals, electronics, and pharmaceuticals.
Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
TCI America (TCI) was founded in 1946 and is a worldwide manufacturer of specialty organic chemicals. The company produces organic laboratory chemicals as well as pharmaceutical, cosmetic, and functional materials. TCI’s product segments include Chemistry, Life Science, Materials Science, Analytical Chemistry, and Custom & Bulk. For materials science, the company manufactures battery materials, nanocarbon materials, and magnetic materials. For life sciences, the company produces antibodies, reagents, and chemicals for cancer research. The company produces HLC, NMR, various chemicals, and resins and media for analytical chemistry.
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
Hemanshu Chemicals was established in 1990 in Maharashtra, India, and is a manufacturer and supplier of chemicals, solvents, and pharmaceuticals that are used to make a wide range of products, such as food additives, paints, adhesives, and lubricants. The company makes chemical products like Dexamethasone sodium phosphate, Beclomethasone dipropionate, Magnesium hydroxide IP, and Benzoyl chloride. It also imports Magnesium hydroxide, 4- Hydroxybenzaldehyde, Magaldrate, and hydroxybenzaldehyde from countries such as Korea, China, and Taiwan.
Jigs Chemical was established in 1998 and is based in India with global offices in the USA, UK, Canada, and Australia. Jigs Chemical is a manufacturer, distributor, and marketing & sales provider for organizations in India, specializing in chemicals and active pharmaceutical ingredients for pharmaceutical, agriculture, ceramics, metal treatment, and other industries. Jigs Chemical helps facilitate international customers to obtain chemicals from India, providing import and export assistance. Jigs Chemical’s product catalog includes over 40000 active pharmaceutical ingredients, commonly called APIs, their respective intermediates, and other chemicals.
BOC Sciences is headquartered in Shirley, New York as a brand of BOCSCI Inc. The company is a developer, manufacturer, marketer, and distributor of premium chemicals, emphasizing small molecule synthesis, biosynthesis, purification, and characterization used in academia, pharmaceuticals, biotech, CDMO, material sciences, and agriculture industries, supporting research and production. The company’s products include thousands of inhibitors, nucleotides, metabolites, and isotope-labeled products. The company offers custom synthesis and manufacturing, analytical services, antibody-drug conjugate development, and strain engineering and fermentation services.
BioCrick Co., Ltd is located in Chengdu Tianfu Life Science Park in Sichuan Province, China. The company creates a natural product library which provides small molecular compounds with potential biological and pharmacological activities for pharmaceutical, agricultural, and biotechnology companies worldwide. The company’s database includes more than 8,000 compounds collected from natural sources such as as medicinal plants, herbs, fungus, and microbes. The company also a provider of peptides and lab reagents for biological research, carrying a product line in apoptosis, epigenetic, and cancer biology.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | Sinco Pharmachem Inc. |
33.3%
|
| 2 | GLPBIO Technology LLC |
33.3%
|
| 3 | Santa Cruz Biotechnology, Inc. |
33.3%
|
Derivation Method
The ranking is calculated based on the click share within the xanthone page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
United States of America
|
4 | 57.1% |
|
Japan
|
2 | 28.6% |
|
India
|
1 | 14.3% |
