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This section provides an overview for indene as well as their applications and principles. Also, please take a look at the list of 5 indene manufacturers and their company rankings. Here are the top-ranked indene companies as of December, 2024: 1.JFE Chemical Corporation, 2.KANTO CHEMICAL CO.,INC., 3.Central Drug House.
Table of Contents
Indene is a component of coal tar, found in the distillation distillate of coal tar neutral oil and refined by removing tar acids. Pure indene is colorless, turning pale yellow due to polymerization or oxidation during storage. It is unstable and prone to polymerization reactions, absorbing oxygen to form oxides. When heated, it decomposes, emitting irritating smoke and gases.
Indene is used in organic synthesis for optical functional materials, functional resins, and pharmaceutical intermediates. It serves as a resin modifier in the polymerization of coumarone and styrene, enhancing the properties of various resins. Coumarone-indene resin, different from petroleum resins, offers adhesiveness, mechanical, and electrical properties, and is used in rubber, paints, and epoxy resins.
Indene, a bicyclic hydrocarbon with a molecular formula of C9H8, is a colorless oily liquid at room temperature, insoluble in water but soluble in organic solvents like ethanol and acetone. It has a melting point of -1.8°C and a boiling point of 181.6°C, and is highly irritating to eyes and skin, with potential damage to kidneys, liver, and spleen upon inhalation.
Indene is obtained from coal tar fractions, extracted by steam distillation after reacting with metallic sodium to form a salt.
Indene undergoes various reactions, including oxidation to form homophthalic acid, and condensation with ethyl oxalate and ketones or aldehydes to yield indene-oxalate and benzofulvene, respectively.
Indene forms the indenyl anion upon proton withdrawal, acting as an η3- ligand and exhibiting the indenyl effect.
Indene, when polymerized with coumarin, forms a thermoplastic resin with a low degree of polymerization. The resulting coumarone-indene resin, obtained from the 160-180°C fraction of coal tar, is brown or black, soluble in aromatic hydrocarbons, and resistant to acids and alkalis.
*Including some distributors, etc.
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Santa Cruz Biotechnology, Inc., established in 1991 and headquartered in Dallas, Texas, is an American manufacturer and supplier specializing in biological products for medical research. Initially providing antibodies to the research community, they expanded their offerings to include gene silencers like siRNA and shRNA (plasmid and lentiviral), targeting all known mouse and human genes. Over time, Santa Cruz Biotechnology provides over 175,000 research biochemicals under the brand ChemCruz, including protein-interacting inhibitors, substrates, and activators, tailored for studying protein functions. The company offers monoclonal primary antibodies, designed for various mammalian and non-mammalian protein targets, along with corresponding binding secondary antibodies.
Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
Founded in 1981, Central Drug House Ltd. serves the scientific community via manufacturing and marketing a library of over 9,000 products to laboratory fine chemicals and dehydrated culture media with emphasis on purity and service. Examples are acids & bases, adsorbents, disinfectants, indicator papers, oils, and solvents. CDH provides bio chemicals, research chemicals, laboratory reagents, various solvents, stains & indicators, and dehydrated culture media. CDH is ISO 9001 certified and CDHs’ products are in compliance with specifications of IP, BP, USP, and EP standards.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | JFE Chemical Corporation |
28.6%
|
| 2 | KANTO CHEMICAL CO.,INC. |
25.0%
|
| 3 | Central Drug House |
21.4%
|
| 4 | MilliporeSigma |
14.3%
|
| 5 | Santa Cruz Biotechnology, Inc. |
10.7%
|
Derivation Method
The ranking is calculated based on the click share within the indene page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
Japan
|
2 | 50.0% |
|
United States of America
|
1 | 25.0% |
|
India
|
1 | 25.0% |
