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This section provides an overview for chromatography columns as well as their applications and principles. Also, please take a look at the list of 12 chromatography column manufacturers and their company rankings. Here are the top-ranked chromatography column companies as of December, 2024: 1.Science and Health with Chemistry Co.,Ltd., 2.Biotech Fluidics AB, 3.Chrom Tech, Inc.
Table of Contents
A chromatography column is a narrow, tube-shaped apparatus packed with a stationary phase, primarily employed in liquid chromatography.
While chromatography encompasses techniques such as High-Performance Liquid Chromatography (HPLC) and gas chromatography, products labeled as "chromatography columns" or "columns for chromatography" typically refer to liquid chromatography (open column/flash chromatography) or ion chromatography. These columns play a crucial role in chromatography by separating and purifying mixtures through solute adsorption and elution.
Chromatography columns serve as essential tools in chromatography, a technique utilized for the separation and purification of mixtures across diverse fields including chemistry, fragrances, food, and pharmaceuticals. Noteworthy applications encompass:
This analytical approach proves indispensable for quality control and component identification across a spectrum of domains, from fundamental research to industrial applications.
Chromatography involves segregating and detecting mixtures by utilizing a gas or liquid as the mobile phase and exploiting the physicochemical interactions between the sample substances and the stationary phase housed in the column. Chromatography columns are either filled with a stationary phase for single-use or come prefilled. Typically, these columns find application in liquid chromatography.
Columns utilized in open or flash chromatography are cylindrical glass apparatuses not prepacked with a stationary phase. The top remains open, while a tap is situated at the bottom. The stationary and mobile phases are introduced from the top, and the tap regulates the eluting solvent flow. The process entails:
Ion chromatography segregates and purifies using ionic interactions, capable of measuring inorganic anions and cations, along with certain organic acids and amines. The chromatography column's stationary phase often comprises ion-exchange resins.
Given that ion chromatography necessitates pressurizing the electrolyte solution mobile phase via a pump, akin to HPLC, the columns are typically constructed from metal or resin and come prefilled with a stationary phase. They can be reused post-cleaning with a washing solvent.
Chromatography columns encompass glass apparatuses for open columns and metal or resin columns for ion chromatography.
Columns used in ion chromatography are tailored specifically for either cation chromatography (cation columns) or anion chromatography (anion columns), each packed with ion-exchange resins of opposite polarity.
There are various types of cation and anion columns, including specialized variants for specific applications. For instance, anion columns may specialize in analyzing polyphosphates in seafood or in the analysis of ions such as I- and SCN-.
Guard columns, capable of filtering insoluble solid particles, are employed to prevent column contamination.
*Including some distributors, etc.
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MACHERY-NAGEL was established in 1911 in Düren, Germany, has subsidiaries in Germany, Switzerland, France, and the United States and it is manufacturer of analytical systems and components. The company produces a diverse range of products, including filter papers, extraction thimbles, membranes, rapid test papers, visual test kits, photometers, microbiological analysis tools, reagent cases, photometric test kits, solid-phase extraction equipment, vials and caps, TLC (Thin-Layer Chromatography) materials, GC (Gas Chromatography) supplies, flash chromatography components, and bioanalysis test kits. It also has expertise in waste management. The company holds ISO9100, EN ISO13486, and IvD 98/79/EC certifications.
Sartorius AG was founded in 1870 and specializes in lab products and bioprocess solutions. The company has its headquarters in Gottingen, Germany with locations in major biopharma markets including the Americas and Asia Pacific. Sartorius' range of solutions includes instruments, consumables, and services for chemical, food, biopharmaceutical, and academic laboratories. The company offers automated bioreactors and fermenters, a portfolio of cell culture media, and a range of laboratory essentials such as balances and filtration devices. The company also offers regular preventive maintenance services.
As a leading company in ion chromatography, Science and Health with Chemistry Co.,Ltd. (Kaken-Kagaku) are engaged in import/export/agency sales of scientific and medical instruments and consumables and also in technical consulting and technology trade. We supply high-quality yet cost-effective products to our customers around the world, and we are committed to solving the various scientific and health problems they face from the viewpoint of chemistry.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | Science and Health with Chemistry Co.,Ltd. |
33.0%
|
| 2 | Biotech Fluidics AB |
11.9%
|
| 3 | Chrom Tech, Inc |
9.2%
|
| 4 | imChem |
8.3%
|
| 5 | Sartorius AG |
7.3%
|
| 6 | Glantreo |
6.4%
|
| 7 | Global Life Sciences Solutions USA LLC |
6.4%
|
| 8 | MACHEREY-NAGEL |
5.5%
|
| 9 | Maxi Scientific Instruments Co., Ltd. |
3.7%
|
| 10 | Hawach Scientific Co.,Ltd |
3.7%
|
Derivation Method
The ranking is calculated based on the click share within the chromatography column page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
United States of America
|
1 | 33.3% |
|
Germany
|
1 | 33.3% |
|
JAPAN
|
1 | 33.3% |
