Biomolecular interaction analysis device Dianthus series-NDI-011101

Biomolecular interaction analysis device Dianthus series
Central Scientific Trading Co., Ltd.

About This Product

■SummaryNanoTemper's two unique technologies (microscale thermophoresis and Spectral Shift) accurately and quickly capture the interaction between two molecules and provide it as Kd. Since it does not have a flow path, regular maintenance is not required, and Kd can be determined with a very simple operation. Monolith is a standard type that measures with a capillary, and Dianthus is a high-throughput type that measures with a plate.

■Microscale thermophoresisHeat is applied to a sample in a solution, and changes in fluorescence intensity due to thermal equilibrium movement of the target molecule and changes in the fluorescence intensity of the molecules themselves are captured, and changes in fluorescence intensity over time are measured. The degree of this change in fluorescence intensity changes depending on whether the ligand is bound or not. Measure the change in fluorescence intensity for each ligand concentration, draw a sigmoid curve based on the difference in the changes in fluorescence intensity, and calculate Kd.

■Spectral ShiftWhen a ligand binds to a target, the fluorescence spectrum changes. In this measurement technique, the target is labeled with a fluorescent label, a fixed amount is mixed with a series of dilutions of the ligand, excited at 590 nm, and the binding state is detected as a shift in the fluorescence spectrum.

To detect this movement, fluorescence is detected at two wavelengths, 650 nm and 670 nm, and KD is calculated by plotting the ratio of the fluorescence intensities on the vertical axis and the ligand concentration on the horizontal axis. Since ratios are used in the KD calculation process, the calculation formula is (1). Therefore, noise can be canceled out by calculation, improving the S/N ratio. This makes it possible to detect even subtle shifts with great precision.

■Quick measurement・Monolith One Kd measurement time is about 10 minutes (24 capillary measurements)
・Measurement time for Dianthus 1 plate (384 wells) is improved by about 30 minutes.

■Molecular weight of binding targetMeasures Kd from pM to mM for all molecular weights from ions to ribosomes

■No immobilization required, no high purity purification required (when using His-tag labeling)- Can be analyzed in any buffer and bioliquid (cell lysate, serum)
・Measurement without immobilization
・Various options such as labeling and measurement, label-free measurement, etc.

■Improve research efficiency・Easy operation that even beginners can understand
・No regular maintenance required as there is no flow path

Model
There is 1 model available for this product.

Product
Biomolecular interaction analysis device Dianthus series

Handling Company
Central Scientific Trading Co., Ltd.

Categories

Analyzers

Spectroscopic Analyzer

10+ people viewing

Last viewed: 12 hours ago

Free
Get started with our free quotation service - no cost, no obligation.

No Phone Required
We respect your privacy. You can receive quotes without sharing your phone number.

1 Models of Biomolecular interaction analysis device Dianthus series

Image	Part Number	Price (excluding tax)	Product code	Detector
	NDI-011101	Available upon quote	Dianthus Pico	Optics: Pico Red MST + Spectral Shift

Customers who viewed this product also viewed

Reviews shown here are reviews of companies.

UV-visible spectrophotometer Lambda 850+

Cosmo Trading Co., Ltd.

4.0

200+ people viewing

Last viewed: 19 hours ago

Response time: 24.30 hours

Spectroscopic Analyzer

3 models listed

Compact portable type emission spectrometer belec DE-TECT

OES Co., Ltd.

220+ people viewing

Last viewed: 2 hours ago

Response time: 25.32 hours

Spectroscopic Analyzer

UV-visible near-infrared spectrophotometer Lambda 1050+

Cosmo Trading Co., Ltd.

4.0

210+ people viewing

Last viewed: 22 hours ago

Response time: 24.30 hours

Spectroscopic Analyzer

4 models listed

Fluorine gas measuring device FU-100

Photoscience Co., Ltd.

310+ people viewing

Last viewed: 5 hours ago

Response time: 2.18 hours

Spectroscopic Analyzer

A completely new price range and ultra-compact emission spectrometer belec OPTRON

OES Co., Ltd.

200+ people viewing

Response time: 25.32 hours

Spectroscopic Analyzer

Fourier transform infrared spectrometer near infrared/mid infrared/far infrared Spectrum Two/Spectrum Two+

Cosmo Trading Co., Ltd.

4.0

240+ people viewing

Last viewed: 7 hours ago

Response time: 24.30 hours

Spectroscopic Analyzer

2 models listed

Belec compact port-HLC, a hybrid portable type emission spectrometer that can be mounted on a dedicated cart and moved

OES Co., Ltd.

190+ people viewing

Response time: 25.32 hours

Spectroscopic Analyzer

Belec IN-SPECT, a high-performance desktop metal materials analyzer with a maintenance-free design

OES Co., Ltd.

170+ people viewing

Last viewed: 10 hours ago

Response time: 25.32 hours

Spectroscopic Analyzer

Fourier transform infrared spectrometer near-infrared/mid-infrared/far-infrared Spectrum 3 series

Cosmo Trading Co., Ltd.

4.0

350+ people viewing

Last viewed: 1 hour ago

Response time: 24.30 hours

Spectroscopic Analyzer

5 models listed

Belec vario lab, a unique stationary high-performance metal materials analyzer with excellent scalability

OES Co., Ltd.

210+ people viewing

Last viewed: 8 hours ago

Response time: 25.32 hours

Spectroscopic Analyzer

Spectrm 3 Optica, a Fourier transform infrared spectrometer dedicated to measuring optical materials

Cosmo Trading Co., Ltd.

4.0

160+ people viewing

Last viewed: 19 hours ago

Response time: 24.30 hours

Spectroscopic Analyzer

AlloyChecker, a new handheld laser spectrometer for metal identification

OES Co., Ltd.

210+ people viewing

Last viewed: 19 hours ago

Response time: 25.32 hours

Spectroscopic Analyzer

See More Spectroscopic Analyzer Products

Other products of Central Scientific Trading Co., Ltd.

Reviews shown here are reviews of companies.

High-pressure homogenizer (cell crusher) EmulsiFlex C5

Central Scientific Trading Co., Ltd.

50+ people viewing

Response time: 26.55 hours

Homogenizers

Tube Pump Programmable/Constant Pressure Tube Pump PeristalicPump

Central Scientific Trading Co., Ltd.

40+ people viewing

Response time: 26.55 hours

Pump Tubing

3 models listed

Syringe pump remote control model 70-3514

Central Scientific Trading Co., Ltd.

30+ people viewing

Response time: 26.55 hours

Syringe Pumps

Inhalation formulation particle size evaluation device Twin Impinger

Central Scientific Trading Co., Ltd.

30+ people viewing

Last viewed: 19 hours ago

Response time: 26.55 hours

Visible spectrophotometer Ultrospec 10 (Ultrospec 10)

Central Scientific Trading Co., Ltd.

50+ people viewing

Last viewed: 2 hours ago

Response time: 26.55 hours

Colorimeters

4 models listed

Vacuum Freeze Dryer: Stationary type for research, floor-standing customized type for laboratory use, LYCF series

Central Scientific Trading Co., Ltd.

20+ people viewing

Response time: 26.55 hours

Freeze Dryers

Culture environment maintenance tool CondoCELL

Central Scientific Trading Co., Ltd.

30+ people viewing

Last viewed: 9 hours ago

Response time: 26.55 hours

Incubator Apparatuses

Simple water quality test kit High sensitivity water quality test kit VISOCOLOR HE

Central Scientific Trading Co., Ltd.

30+ people viewing

Last viewed: 1 hour ago

Response time: 26.55 hours

Water Testers

2 models listed

Inspection labor-saving equipment Microbial fluorescence image measuring device Bactester

Central Scientific Trading Co., Ltd.

30+ people viewing

Response time: 26.55 hours

Image Measuring Instruments

Rapid detection of microorganisms Highly sensitive PCR food poisoning bacteria detection system Qualivax™ system

Central Scientific Trading Co., Ltd.

30+ people viewing

Last viewed: 3 hours ago

Response time: 26.55 hours

Colorimeters

Strip plate washer 50TS series 50TS8-SN

Central Scientific Trading Co., Ltd.

40+ people viewing

Last viewed: 10 hours ago

Response time: 26.55 hours

Cleaning Systems

2 models listed

View more products of Central Scientific Trading Co., Ltd.

About Company Handling This Product

Central Scientific Trading Co., Ltd.

Related search keywords

This is the version of our website addressed to speakers of English in the United States. If you are a resident of another country, please select the appropriate version of Metoree for your country in the drop-down menu.

Biomolecular interaction analysis device Dianthus series Central Scientific Trading Co., Ltd.

About This Product

■Summary

■Microscale thermophoresis

■Spectral Shift

■Quick measurement

■Molecular weight of binding target

■No immobilization required, no high purity purification required (when using His-tag labeling)

■Improve research efficiency

1 Models of Biomolecular interaction analysis device Dianthus series

NDI-011101

Customers who viewed this product also viewed

Other products of Central Scientific Trading Co., Ltd.

About Company Handling This Product

Related search keywords

Biomolecular interaction analysis device Dianthus series
Central Scientific Trading Co., Ltd.