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  4. Achieving high-throughput ion channel screening with simple operation Qube 384 (Sofion Bioscience Co., Ltd.)
Achieving high-throughput ion channel screening with simple operation Qube 384-Qube 384
Achieving high-throughput ion channel screening with simple operation Qube 384-Sofion Bioscience Co., Ltd.

Achieving high-throughput ion channel screening with simple operation Qube 384
Sofion Bioscience Co., Ltd.

About This Product

Using advanced electrophysiological techniques, we provide reliable data from the early stages of your drug discovery program. This saves valuable time before bringing ion channel agonists to market. Sophion's HTS system, the Qube 384, makes ion channel research easy. By combining GigaSeal-based current recording with unattended operation, drug discovery research can be conducted more efficiently. Qube fixes the membrane potential of individual cells at half the channel activation potential to more accurately elucidate the mechanism of action of candidate compounds. Experimental temperature can also be controlled at the cellular level and can be raised or lowered. Temperature data can also be used for subsequent analysis

■Qube bridges the gap between high-throughput and high-quality ion channel assays, allowing you to:

・Online Vxx evaluation: Both activation potential and inactivation potential can be measured, and the measured value can be immediately applied to the fixed potential (Vhold) or stimulation potential (Vstim) during the same experiment. ・Easily achieves success rate of 90-95% (e.g. hERG, NaV1.4, CaV1.2) ・True unattended operation - 6,000 well tests can be performed with one click - Experiments can be performed at night Compatible with all ion channel assays, including voltage-gated and ligand-gated applications, current clamp, etc. ・Supports whole cell recording and perforated patch recording ・High quality data and high SN ratio achieved by GigaSeal recording ・Temperature control - Accurately inject solutions at specified concentrations into measurement wells by processing compound solutions using highly reliable AI technology. ・The simple and easy-to-use software and interface allow anyone to start operating Qube immediately, making it easy to relocate staff in charge. ・Powerful analysis ability with Sophion Analyzer

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    Achieving high-throughput ion channel screening with simple operation Qube 384

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1 Models of Achieving high-throughput ion channel screening with simple operation Qube 384

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Achieving high-throughput ion channel screening with simple operation Qube 384-Part Number-Qube 384

Qube 384

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