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  4. Latest magnetic microspheres Magnetic Microspheres & Particles (Techno Chemical Co., Ltd.)
Latest magnetic microspheres Magnetic Microspheres & Particles-Magnetic Microspheres & Particles
Latest magnetic microspheres Magnetic Microspheres & Particles-Techno Chemical Co., Ltd.

Latest magnetic microspheres Magnetic Microspheres & Particles
Techno Chemical Co., Ltd.

About This Product

■Immune assay

In in vitro diagnostics and screening that measure antigens contained in biochemical samples, immunoassays using a sandwich method are widely used, using a specific antibody immobilized on a carrier and a detection antibody labeled with an enzyme or fluorescence. In ELISA, which uses a microwell plate as a solid phase, the surface area for adsorption and binding of specific antibodies is limited, and changes in detection sensitivity and scale require optimization. In the Particle-Based Enzyme/Fluorescent Immuno Assay, which uses particles as a solid phase, it is possible to dramatically increase the surface area, and it is also relatively easy to change the sensitivity and scale by changing the number of added particles. You can. In the EIA/FIA method using particles, it is necessary to remove unreacted enzymes and fluorescently labeled detection antibodies from the reaction system (B/F separation) before detection, and immune complexes are removed from the reaction system by particle sedimentation. Separated. Magnetic particles can be rapidly sedimented by a magnetic field and easily redispersed by removing the magnetic field. Unlike centrifugation, magnetic separation is easily adaptable to automation and scale changes, and magnetic particles are widely used in applications that require automation and high throughput.

■Separation of cells, nucleic acids, and proteins

Magnetic particles are also used in applications such as cell separation, nucleic acid purification, and protein removal where binding capacity is of particular importance. Since it is difficult to separate only cells bound to particles using centrifugation that utilizes the difference in specific gravity (difference in sedimentation speed), magnetic particles are required for cell separation. Since magnetic separation minimizes the physical stress on cells other than the bound cells, negative selection, which binds and precipitates cells other than the target cells, is used for cell isolation and enrichment.

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    Latest magnetic microspheres Magnetic Microspheres & Particles

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Techno Chemical Co., Ltd.

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