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Biological stress visualization mouse (UMAI-Luc mouse)
Anhyo Center Co., Ltd.


About This Product

■ Biological stress visualization mouse

Biological stress visualization mouse (UMAI-Luc mouse) is a transgenic mouse carrying the UMAI-Luc gene that allows visualization of ATF4 translation induction using luciferase as a reporter.

■ Biological stress and ATF4

Stress is thought to play an important role in various pathological conditions in humans, and living organisms respond to various types of stress using common signal pathways. This reaction is called integrated stress response (ISR), and the transcription factor Activating transcription factor 4 (ATF4) plays a central role in regulating the expression of downstream stress response genes. Stresses involved in this pathway include amino acid starvation, viral infection, endoplasmic reticulum stress, and oxidative stress.

■Price (excluding tax)

・Frozen embryos (50): 100,000 yen ・2 pairs of male and female: 340,000 yen ・Breeding license price: Academia price: 200,000 yen (no breeding/breeding restrictions at the purchasing facility), price for commercial companies: 200,000 yen (mating/breeding restrictions at the purchasing facility (up to 15 per year), exceeding the limit) (Additional cost for number of animals)

  • Product

    Biological stress visualization mouse (UMAI-Luc mouse)

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