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LNP manufacturing equipment Large capacity, high-grade production equipment that is easy to scale up Fully automatic nanoparticle manufacturing equipment for GMP-compliant production Nano us-Nano us
LNP manufacturing equipment Large capacity, high-grade production equipment that is easy to scale up Fully automatic nanoparticle manufacturing equipment for GMP-compliant production Nano us-MUTUAL CORPORATION

LNP manufacturing equipment Large capacity, high-grade production equipment that is easy to scale up Fully automatic nanoparticle manufacturing equipment for GMP-compliant production Nano us
MUTUAL CORPORATION

MUTUAL CORPORATION's Response Status

Response Rate

100.0%

Response Time

90.4hours


About This Product

■Features

Since the global pandemic, LNPs (lipid nanoparticles) have attracted attention to speed up vaccine/nucleic acid development. The sterile GMP nano-manufacturing device "Nano us" is a collaboration between the latest reactor (Flexible-Reactor JET) provided by LEON and the manufacturing system provided by Harro Hoefliger. We support solving LNP manufacturing issues such as ``easy to scale up'', ``GMP compliant, and automatic C/SIP compatible''.

■Features

・Fully automatic equipment for continuous production - Fully customizable to meet manufacturing process requirements ・Transfer the data and reactor size verified in NANO lab® directly to the process ・Inline continuous particle size measurement possible - Supports sterile filtering of starting materials in the supply section ・In-line dilution possible ・Automatic CIP/SIP functionality including verification by TOC and conductivity measurements ・Built-in container with built-in filling level, temperature and pressure sensors ・ATEX compatible – Nitrogen deactivation and container grounding for safe handling of large volumes of solvents

■Features of Reactor (Flexible-Reactor JET) technology

・The special reactor structure makes it easy to approach the target particle size and determine production capacity. ・Modular design with replaceable parts (core part and jet part) -Since it uses a modular reactor, it can be equipped with the same reactor as the research machine. Easy to scale up ・Adopts a jet flow principle that achieves a stable mixing process while generating high turbulence ・Nanoparticles can be generated by increasing the concentration of the starting material, and the processing time in the post-process can be significantly shortened. ・Critical Quality Attributes such as particle size, particle size distribution, encapsulation efficiency, etc.

  • Product

    LNP manufacturing equipment Large capacity, high-grade production equipment that is easy to scale up Fully automatic nanoparticle manufacturing equipment for GMP-compliant production Nano us

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1 Models of LNP manufacturing equipment Large capacity, high-grade production equipment that is easy to scale up Fully automatic nanoparticle manufacturing equipment for GMP-compliant production Nano us

Image Part Number Price (excluding tax) Product flow range Equipment weight Equipment dimensions Manufacturer Duct pressure
LNP manufacturing equipment Large capacity, high-grade production equipment that is easy to scale up Fully automatic nanoparticle manufacturing equipment for GMP-compliant production Nano us-Part Number-Nano us

Nano us

Available upon quote

50ml/min~1,200ml/min

1,500kg

W2,500×D1,000xH2,300 (mm)

Harro Höfliger

Up to 40 bar

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About Company Handling This Product

Response Rate

100.0%


Response Time

90.4hrs

Company Overview

Mutual Corporation, founded in 1956 with headquarters in Osaka, Japan, is a manufacturer and distributor of fo...

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