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Cardiac cells are used to study the function and pathophysiology of the human cardiovascular system. Many of these cell types are derived from healthy donors, type I and type II diabetic donors. ■Origin tissue ・Aortic adventitia fibroblasts: isolated from the adventitia of the ascending or descending aorta ・Cardiac fibroblasts: isolated from atrial and ventricular tissue ・Endothelial cells: isolated from aorta and coronary artery ・Microvascular endothelial cells: isolated from ventricular tissue ・Smooth muscle cells: isolated from aorta and coronary artery ■Research use ·arrhythmia ・Cardiomyopathy ·heart failure ・Preventive cardiology ・Vascular research Cell testing and standards ■Endothelial cells Positive acetylated low-density lipoprotein (LDL) uptake (normal endothelial cells take up LDL and store it in vesicles); von Willebrand factor expression/Factor VIII positive (positive staining indicates that endothelial cells are normal) vonWillebrand factor synthesis is essential for blood clotting); normal cells are guaranteed to divide 15 times (when using Clonetics™ media and reagents) ■Fibroblasts Cardiac fibroblasts: positive collagen type I staining, negative von Willebrand factor (factor VIII); normal cells guaranteed to divide 5 times (when using Clonetics™ media and reagents) Aortic adventitia fibroblasts: α-actin staining Negative; normal cells guaranteed to divide 5 times (when using Clonetics™ media and reagents) ■Smooth muscle Post-differentiation alpha-actin staining positive and von Willebrand factor negative; normal cells guaranteed to divide 15 times (when using Clonetics™ media and reagents)
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We provide a wide variety of human-derived cells in the form of frozen cells. Primary cells/mediumHandling Company
Lonza Co., Ltd.Image | Price (excluding tax) |
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