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This section provides an overview for sodium butyrate as well as their applications and principles. Also, please take a look at the list of 10 sodium butyrate manufacturers and their company rankings. Here are the top-ranked sodium butyrate companies as of August, 2025: 1.Titan Biotech Limited, 2.Cayman Chemical Company, 3.Tokyo Chemical Industry Co., Ltd..
Table of Contents
Sodium butyrate is a chemical compound formed when butyric acid is converted into its sodium salt.
It is a colorless to white crystalline solid that is highly soluble in water and has a slightly unpleasant odor. Its molecular formula is CH3(CH2)2COONa, and its molecular weight is 110.09. Butyric acid is a short-chain fatty acid with a strong, distinctive odor, often compared to cheese or sweat. It is naturally produced in the human gut by intestinal bacteria fermenting dietary fiber. Sodium butyrate is a more stable and consumable form of butyric acid.
In the human colon, butyric acid serves as the main energy source for the colonic mucosa. It plays a role in maintaining the intestinal environment, suppressing inflammation, and regulating immunity. Oral intake of sodium butyrate can help increase butyric acid levels in the intestines and support gut health.
Sodium butyrate is widely used in health, animal husbandry, and research. Major applications include the following:
Sodium butyrate is used as an ingredient in dietary supplements aimed at improving intestinal health. It may help regulate bowel movements and alleviate symptoms of irritable bowel syndrome (IBS) and ulcerative colitis by improving gut microbiota balance and enhancing the barrier function of the large intestine.
Sodium butyrate is also used as a feed additive for livestock. It helps regulate the intestinal environment of animals, promoting growth and preventing disease. It is being explored as an alternative to antibiotics, particularly in pigs and poultry, and is gaining attention for its role in antibiotic-free livestock production.
In medical research, sodium butyrate is studied as a potential histone deacetylase (HDAC) inhibitor. HDAC inhibitors are being developed for treating cancer, infectious diseases, and inflammatory conditions.
*Including some distributors, etc.
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Cayman Chemical Company is a manufacturer of life science research products founded in 1979 in Ann Arbor, Michigan, USA. They offer a diverse array of analytical standards, reagents, and other products for research in cancer, oxidative injury, epigenetics, neuroscience, inflammation, as well as metabolism, and other areas. The company supplies small molecules, biochemicals, assay kits, antibodies, and proteins to research scientists across academic, biotechnology, and pharmaceutical institutions. Cayman Chemical Company holds dual accreditations to ISO/IEC 17025:2017 and ISO 17034:2016 by ANAB Accreditation Services.
TCI America (TCI) was founded in 1946 and is a worldwide manufacturer of specialty organic chemicals. The company produces organic laboratory chemicals as well as pharmaceutical, cosmetic, and functional materials. TCI’s product segments include Chemistry, Life Science, Materials Science, Analytical Chemistry, and Custom & Bulk. For materials science, the company manufactures battery materials, nanocarbon materials, and magnetic materials. For life sciences, the company produces antibodies, reagents, and chemicals for cancer research. The company produces HLC, NMR, various chemicals, and resins and media for analytical chemistry.
Titan Biotech Limited is based in Delhi, India, and has been a manufacturer and exporter of various biological products since its establishment in 1992. The company offers a range of products such as ox-bile extract, protein hydrolysates, amino acid mixtures, liver extracts, plant growth promoters, and more. These products are used in diverse industries, including food and beverages, biotechnology and fermentation, veterinary and animal feed, microbiology culture media, and plant tissue culture media.
Founded in 1981, Central Drug House Ltd. serves the scientific community via manufacturing and marketing a library of over 9,000 products to laboratory fine chemicals and dehydrated culture media with emphasis on purity and service. Examples are acids & bases, adsorbents, disinfectants, indicator papers, oils, and solvents. CDH provides bio chemicals, research chemicals, laboratory reagents, various solvents, stains & indicators, and dehydrated culture media. CDH is ISO 9001 certified and CDHs’ products are in compliance with specifications of IP, BP, USP, and EP standards.
Glentham Life Sciences is based in Corsham, United Kingdom. Glentham Life Sciences is a leading supplier of fine chemicals, raw materials, reagents, and life science products. Glenthem also offers a number of services including custom packaging, call-off orders, and safety documentation. Glentham’s product offerings include chemicals such as amino acids, antibiotics, APIs, biochemicals, buffers, carbohydrates, chitin, chitosan, detergents, dyes, stains, enzymes, inorganic, peptide reagents, phytochemical, raw materials, solvents, steroids, and vitamins among others.
Ranking as of August 2025
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | Titan Biotech Limited |
16.7%
|
| 2 | Cayman Chemical Company |
16.7%
|
| 3 | Tokyo Chemical Industry Co., Ltd. |
16.7%
|
| 4 | Singao Agribusiness Development Co.,Ltd |
8.3%
|
| 5 | Eubiotics |
8.3%
|
| 6 | West Bengal Chemical Industries Limited |
8.3%
|
| 7 | Conflate Chemtech |
8.3%
|
| 8 | Central Drug House |
8.3%
|
| 9 | Glentham Life Sciences Limited |
8.3%
|
Derivation Method
The ranking is calculated based on the click share within the sodium butyrate page as of August 2025. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
India
|
4 | 57.1% |
|
United States of America
|
1 | 14.3% |
|
Japan
|
1 | 14.3% |
|
United Kingdom
|
1 | 14.3% |
