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This section provides an overview for hexanones as well as their applications and principles. Also, please take a look at the list of 9 hexanone manufacturers and their company rankings. Here are the top-ranked hexanone companies as of December, 2024: 1.Alfa Aesar, Thermo Fisher Scientific..
Table of Contents
Hexanone is a ketone characterized by the chemical formula C6H12O, encompassing two isomers: 2-hexanone and 3-hexanone. These organic compounds feature a CO carbonyl group substituted at the 2- or 3-position on a linear hexane carbon chain.
The CAS registration numbers for 2-hexanone and 3-hexanone are 591-78-6 and 589-38-8, respectively. Hexanal represents another class of isomers with a carbonyl group at the 1-position, classified as aldehydes.
2-hexanone is primarily used in solvents and paints, noted for its excellent solubility in cellulose nitrate, vinyl polymers, copolymers, natural, and synthetic resins. Its photochemical inertness makes it a preferred solvent for synthesizing natural product-derived and optically active organic compounds.
Similarly, 3-hexanone serves as a solvent in organic synthesis. Both isomers are also important intermediates in organic synthesis processes.
Known as methyl butyl ketone, 2-hexanone features a molecular weight of 100.16, with a melting point of -55.5°C and a boiling point of 127.6°C. It appears as a clear colorless to pale yellow liquid with a strong acetone-like odor and has a density of 0.8113 g/mL. It is soluble in ethanol and acetone, slightly soluble in water, with a flash point of 35°C.
Also referred to as ethyl propyl ketone, 3-hexanone has a molecular weight of 100.16, with a melting point of -55°C and a boiling point of 123°C. It is a clear, colorless to slightly yellow liquid with a density of 0.814 g/mL and water solubility of 14 g/L. Notably flammable, it has a low flash point of 14°C.
Both 2-hexanone and 3-hexanone are available as reagent products in 5mL and 25mL volumes, designed for ease of use in laboratory settings. They are typically stored and handled at room temperature.
Under proper storage conditions, both isomers are stable, although 2-hexanone vapor/air mixtures may become explosive when heated. Avoid high temperatures to prevent explosive scenarios.
Combustion of these compounds produces carbon oxides, necessitating storage away from ignition sources. They react with oxidizing agents and strong bases.
Both isomers are flammable as liquids and vapors. 2-hexanone is particularly notable for its metabolism into 2,5-hexanedione, a neurotoxic compound. Hazards include strong eye irritation, potential fertility or fetal harm, respiratory irritation, and risks of drowsiness, dizziness, and long-term nervous system damage.
Due to their hazardous nature, both 2-hexanone and 3-hexanone are regulated. Compliance with these regulations is mandatory for safe handling.
*Including some distributors, etc.
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Spectrum Chemical MFG Corp. was founded in 1971, is headquartered in New Brunswick, New Jersey, and has facilities in Gardena, California. Spectrum is a fine chemical manufacturing company with an emphasis on USP, NF, FCC, BP, EP, JP, and ACS grade products, and is ISO 9001:2015 certified. Spectrum primarily serves the analytical, biopharmaceutical, food & beverage, personal care, and pharmaceutical chemicals industries. Spectrum has 4 product segments which are chemicals, equipment, supplies, and safety.
BeanTown Chemical corporation, a company founded in 2013 and headquartered in Hudson, NH, is a manufacturer and distributor of a line of specialty chemicals including organics, inorganics, and metals. The company offers over 7000 products that are primarily used for research and development in the pharmaceutical industry, chemical industry, government institutions and academia. These products are offered in pre-packaged catalogue sizes and in semi-bulk and bulk quantities. BTC has significant experience with custom synthesis and offers special packaging services in dozens of different configurations.
Santa Cruz Biotechnology, Inc., established in 1991 and headquartered in Dallas, Texas, is an American manufacturer and supplier specializing in biological products for medical research. Initially providing antibodies to the research community, they expanded their offerings to include gene silencers like siRNA and shRNA (plasmid and lentiviral), targeting all known mouse and human genes. Over time, Santa Cruz Biotechnology provides over 175,000 research biochemicals under the brand ChemCruz, including protein-interacting inhibitors, substrates, and activators, tailored for studying protein functions. The company offers monoclonal primary antibodies, designed for various mammalian and non-mammalian protein targets, along with corresponding binding secondary antibodies.
Parchem was founded in 1999 and headquartered in Rochelle, New York. Parchem is a distributor of industrial chemicals. Parchem serves nutritional, personal care, pharmaceutical, and specialty chemical industries. Parchem offerings include coatings, adhesives, elastomers, industrial products, petrochemicals, oleochemicals, plastics, rubber, nutritional supplements, cosmetics, consumer products, catalysts, metallic salts, rare earths, flavors & fragrances, industrial & institutional, textiles, other food-related chemicals, dyes, finishes, chemicals for aerospace, oil gas drilling chemicals, electronics, and pharmaceuticals.
Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
FujiFilm Wako Pure Chemical Corporation, founded in 1922 and headquartered in Osaka, Japan, is a manufacturer of laboratory chemicals, specialty chemicals, and clinical diagnostic reagents. The company has three business domains, namely laboratory chemicals, specialty chemicals, and clinical diagnostic reagents, and some of its products include biochemistry reagents, blood transfusion test drugs, battery materials, polymer-related materials, and general reagents. The products are useful in various fields, including electronic, cosmetic, polymeric, pharmaceutical, and medical care. It acquired Sibayagi Co. Ltd. in 2015 and provides custom manufacturing to meet customer requirements.
TCI America (TCI) was founded in 1946 and is a worldwide manufacturer of specialty organic chemicals. The company produces organic laboratory chemicals as well as pharmaceutical, cosmetic, and functional materials. TCI’s product segments include Chemistry, Life Science, Materials Science, Analytical Chemistry, and Custom & Bulk. For materials science, the company manufactures battery materials, nanocarbon materials, and magnetic materials. For life sciences, the company produces antibodies, reagents, and chemicals for cancer research. The company produces HLC, NMR, various chemicals, and resins and media for analytical chemistry.
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
Alfa Aesar is based in Lancashire, United Kingdom. Alfa Aesar is part of Thermo Fisher Scientific, is a manufacturer and supplier of chemicals, metals, and life science products for research and development. Alfa Aesar’s product lines include chemicals, life science, materials & metals, catalysts, and analytical & lab ware. Chemical offerings include inorganic compounds, organic compounds, organometallic, and solvents. Life sciences include biotechnology products, cellular & molecular biology, genomics, and immunology. Materials & metal include alloys, carbon, etchants, and more. Catalysts include ferrocenes, fuel cell products, and precious metals & catalysts. Alfa Aesar also offers custom manufacturing options.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | Alfa Aesar, Thermo Fisher Scientific. |
100.0%
|
Derivation Method
The ranking is calculated based on the click share within the hexanone page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
United States of America
|
4 | 50.0% |
|
Japan
|
3 | 37.5% |
|
United Kingdom
|
1 | 12.5% |
