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This section provides an overview for hydroxyradicals as well as their applications and principles. Also, please take a look at the list of 3 hydroxyradicals manufacturers and their company rankings. Here are the top-ranked hydroxyradicals companies as of December, 2024: 1.AAT Bioquest, Inc., 2.MilliporeSigma.
Table of Contents
Hydroxyradicals, represented by the chemical formula -OH, are radicals corresponding to hydroxy groups. The free group OH and the atomic group OH are referred to as hydroxyl radicals. The cation OH+ is known as the hydroxylium ion, while the anion OH- is termed the hydroxide ion. In the context of a ligand, it is represented by hydroxide or hydroxo. The -OH substituent in a compound is called a hydroxy group.
Hydroxyradicals are the three-electron-reduced form of oxygen, being the most reactive and most oxidizing among reactive oxygen species. They can react with various substances, including carbohydrates, proteins, and lipids. Due to their extremely high reactivity, hydroxyradicals have a very short lifespan in normal environmental conditions and disappear rapidly after formation.
Hydroxyl radicals are produced during certain chemical reactions, causing oxidation and then quickly disappearing.
In vitro, they can be generated through ultraviolet irradiation of hydrogen peroxide or by the Fenton reaction, which involves the catalytic reaction of hydrogen peroxide with a divalent iron compound under acidic conditions.
In vivo, hydroxyl radicals are produced inside mitochondria and cells, leading to mitochondrial dysfunction and cell damage. They are implicated in the development of diseases like cancer, Parkinson's disease, and dementia. Antioxidants known to neutralize hydroxyl radicals in the body include hydrogen, β-carotene, α-carotene, vitamin E, uric acid, linoleic acid, cysteine, flavonoids, and glutathione.
*Including some distributors, etc.
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Abcam Plc is a British producer and supplier of life science research materials that was established in 1998. Based in Cambridgeshire, United Kingdom, the company offers various cell and tissue products including stem cells and growth factors, proteins such as lysates and peptides, and primary as well as secondary antibodies (e.g. flow cytometry). It also provides various kits for measuring different aspects of living organisms, such as metabolism, immunology, and biomarkers. Abcam Plc serves clients in a wide range of biomedical operations, including pharmaceutical production, vaccine development, and institutional academic research.
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | AAT Bioquest, Inc. |
50.0%
|
| 2 | MilliporeSigma |
50.0%
|
Derivation Method
The ranking is calculated based on the click share within the hydroxyradicals page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
United States of America
|
2 | 100.0% |
