This section provides an overview for diethylenetriamine as well as their applications and principles. Also, please take a look at the list of 12 diethylenetriamine manufacturers and their company rankings. Here are the top-ranked diethylenetriamine companies as of November, 2024: 1.MUBY CHEMICALS, 2.Zhengzhou Meiya Chemical Products Co.,Ltd., 3.SABIC.
Table of Contents
Diethylenetriamine is an organic compound with the chemical formula C4H13N3 and structural formula HN(CH2CH2NH)2. It falls under the category of primary amines and is known by several names, including 2,2'-iminodiethylamine, 2,2'-diaminediethylamine, and bis(2-aminoethyl)amine. Its CAS number is 111-40-0.
Chemically akin to ethylenediamine, it finds use in similar applications. The molecular structure is often compared to that of diethylene glycol.
Diethylenetriamine is utilized in various applications, such as paper wetting and strengthening agents, epoxy resin curing agents, chelating agents, ion exchange resins, fiber treatment agents, and the synthesis of synthetic organic materials. Among these, its most significant use is as a paper wet strengthener.
This compound is integral to the production of polyamide resins through the reaction with adipic acid, further treated with epichlorohydrin. As a fiber treatment agent, it is used in anti-wrinkle agents, surfactants, and dye-fixing agents.
Additionally, it serves roles in agrochemicals as a fungicide, insecticide, and herbicide, and is notably used in epoxy resin-based adhesives and curing agents for thermosetting resins, facilitating cross-linking through reaction with epoxide groups.
Figure 1. Basic Information on Diethylenetriamine
With a molecular weight of 103.17, diethylenetriamine has a melting point of -39.0°C and a boiling point of 204.1°C. At room temperature, it appears as a colorless to yellow viscous liquid and emits an amine odor.
It exhibits high solubility in water, ethanol, and acetone, and is soluble in polar solvents but insoluble in simple hydrocarbons. Its density is 0.955 g/mL. Being a weak base, its aqueous solutions display weak alkalinity.
Available primarily for research and development, diethylenetriamine is sold in various volumes, including 5mL, 25mL, 100mL, 1L, 2.5L, and 18L, accommodating both laboratory use and larger-scale applications affordably.
1. Synthesis of Diethylenetriamine
Figure 2. Synthesis of Diethylenetriamine
Diethylenetriamine can be synthesized by reacting 1,2-dichloroethane with ammonia, or monoethanolamine with ammonia under hydrogenated catalysts. Industrially, it is primarily obtained as a byproduct in the production of ethylenediamine from 1,2-dichloroethane.
2. Chemical Reaction of Diethylenetriamine
Figure 3. Reaction of Diethylenetriamine with Epoxide Groups
It reacts with epoxide groups to form N-alkylated crosslinks, a reaction pivotal in the use of curing agents for epoxy resin adhesives. Diethylenetriamine also acts as a tridentate ligand in coordination chemistry, forming complexes with metals such as in Co(Dien)(NO2)3.
3. Toxicological Information on Diethylenetriamine
Recognized as a hazardous substance, diethylenetriamine exhibits various toxicity levels under the GHS classification, including acute toxicity (oral, dermal, inhalation), skin corrosion/irritation, serious eye damage/eye irritation, respiratory and skin sensitization, and reproductive toxicity.
4. Regulatory Information on Diethylenetriamine
Due to its hazardous properties, diethylenetriamine is subject to regulatory oversight under various laws.
*Including some distributors, etc.
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Spectrum Chemical MFG Corp. was founded in 1971, is headquartered in New Brunswick, New Jersey, and has facilities in Gardena, California. Spectrum is a fine chemical manufacturing company with an emphasis on USP, NF, FCC, BP, EP, JP, and ACS grade products, and is ISO 9001:2015 certified. Spectrum primarily serves the analytical, biopharmaceutical, food & beverage, personal care, and pharmaceutical chemicals industries. Spectrum has 4 product segments which are chemicals, equipment, supplies, and safety.
Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
Junsei Chemical Co. Ltd., established in 1948 and headquartered in Tokyo, Japan, is a manufacturer of chemical reagents and chemical products, including commissioned synthesis of chemical products. Some of the products it makes include Sodium chloride solution, concentrated glycerin, calcium chloride, ascorbic acid, and nitric acid. The chemical products have a wide range of applications and can be used in pathological examination, as food additives, for analysis, and in the pharmaceutical industry. All its plants, including its research institute, are ISO4001 and ISO9001 certified, while its Saitama and Ibaraki plants are equipped with buildings that comply with GMP.
Kishida Chemical Co. Ltd., established in 1924 and headquartered in Osaka, Japan, is a manufacturer of reagents and high-purity chemicals and also does drug discovery support activities. Its product portfolio includes fine chemicals, research chemicals, ionic liquid, organic micro-analytical reagents, and chemical reagents for analysis. The products support several industries, including reagent business, battery material, drug discovery, and life science. The company is ISO 14001 certified and supplies several companies worldwide, including Meterion Advanced Chemicals Inc., Acros Organics, ChemBridge Corporation, Decon Laboratories, and InerBioScreen Ltd.
MUBY CHEMICALS, established in 1976, is a manufacturer and supplier of chemicals and excipients used in pharmaceuticals, cosmetics & personal care, agrochemical, and textile industries. Based in Ankleshwar, Gujarat, India, the company offers Shale gas hydraulic Fracturing Chemicals such as ammonium persulfate, diverting agents, inhibitors, ATMP phosphonate, and encapsulated gel breakers. Some food analytical reagent chemicals include benzyl alcohol, calcium oxide, boric acid, carbamide peroxide, and lithium carbonate. The company is GLP-approved, Kosher Certified, "REACH" Registered, and ISO-9001 Certified.
Nouryon has a history dating back to 1646 Sweden but was officially formed in 2018 after gaining independence from AkzoNobel. The company is a manufacturer of everyday consumer products including personal care and cleaning goods, as well as products for the agricultural, pharmaceutical, and building industries. The company’s brands include Dissolvine, Witbreak, Butanox, and Ferrazone. These brands manufacture products across five product segments: Bleaching and Oxidizing Chemicals and Technologies, Specialty Polymers, Surfactants and Chelating Agents, Polymer Production and Processing Chemicals, and Specialty Chemicals and Intermediates.
Merck, started in 1668 and based in Darmstadt, Germany, is a supplier of solutions and services for research, development, and manufacture of pharmaceutical and biotechnological drug therapies. The company serves the life science industry and has a broad portfolio of 300,000 products, including biopharmaceutical manufacturing, industrial microbiology, reagent, life science research, and water purification products. It is available in 66 countries, brings together six brands, and has several ISO certifications, including ISO 13485, ISO 14001, ISO 13485, and ISO 50001.
Saudi Basic Industries Corporation (SABIC) is a Saudi Arabian manufacturer of chemicals and intermediates established in 1976 and based in Riyadh. The company produces various basic and performance chemicals, as well as intermediates, polymers, agri-nutrients, and specialty composites. They serve companies in the industrial sectors of roughly 50 countries, with a workforce of more than 31,000 employees. SABIC has secondary large facilities in Yanbu and Al-Jubail, and is a parent company of over 38 subsidiaries and affiliate operations in Asia, Africa, Europe, and North America.
Nacalai Tesque Inc., founded in 1846 and headquartered in Kyoto, Japan, is a manufacturer of research chemicals, fine chemicals, diagnostics, and the related instruments. Some of its products include cytokines, nucleic acid electrophoresis, cell dissociation reagents, and sialic acid-related products, and it also offers custom and bulk service for bulk reagents and cell culture media. The company has more than 50 domestic distributors and several worldwide, including Asia, the Middle East, Oceania, Europe, and Africa. It is ISO 9001 and ISO 9002 certified, while the Kyoto South brand and Tesque factory are ISO 14001 certified.
Vizag Chemical International was founded in Andhra Pradesh, India, in 2011. Vizag Chemical International sells chemical-based products for many sectors including automotive, agriculture, airline, deodorizers, construction chemicals, boat maintenance, degreasers, detergents, drain clean products, greases, personal hygiene, lab chemicals and equipment, fuel treatment, metal treatment, tank cleaners, swimming pool and spa chemicals, scale removers, sewage chemical treatment, as well as raw chemicals. Vizag Chemical International also provides a range of services including chemical inspection, logistics, chemical usage supervision, as well as tank cleaning.
Zhengzhou Meiya Chemical Products Co., LTD was founded in 2005 in Henan, China, and is headquartered in Zhengzhou, China. The company is a distributor and exporter of chemicals from China to Europe, Asia, and the Americas. The ISO 9001-certified company specializes in VOC-exempt solvents, paints and coatings, adhesives, PU, and resin for industries such as agriculture, pharmaceuticals, feed, water treatment, and oil field chemicals. The company’s product categories include plant extracts, cosmetics, PU, and resin.
Founded in Mumbai, India in 2006, Otto Chemie Pvt. Ltd. is an ISO 9001:2015 & GMP certified chemical manufacturing company and distributor. Otto Chemie serves customers in many industries including agriculture and food processing, pharmaceuticals, oil & gas, cement, as well as educational and R&D industries. Product offerings include antibiotics, amino acids, vitamins, detergents, ionic liquids, materials science compounds, labware, oil, metal & ceramic science compounds and tools, oils, reagents, solvents.
Ranking as of November 2024
Derivation MethodRank | Company | Click Share |
---|---|---|
1 | MUBY CHEMICALS |
22.3%
|
2 | Zhengzhou Meiya Chemical Products Co.,Ltd. |
10.8%
|
3 | Vizag Chemical International |
9.6%
|
4 | SABIC |
8.9%
|
5 | Junsei Chemical Co.,Ltd. |
8.9%
|
6 | KANTO CHEMICAL CO.,INC. |
8.9%
|
7 | Kishida Chemical Co.,Ltd. |
7.6%
|
8 | Spectrum Chemical Mfg. Corp. |
7.0%
|
9 | Otto Chemie Pvt. Ltd |
5.7%
|
10 | Nouryon |
3.8%
|
Derivation Method
The ranking is calculated based on the click share within the diethylenetriamine page as of November 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
Country | Number of Companies | Share (%) |
---|---|---|
Japan | 4 | 44.4% |
India | 2 | 22.2% |
United States of America | 1 | 11.1% |
Netherlands | 1 | 11.1% |
China | 1 | 11.1% |