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This section provides an overview for glycidols as well as their applications and principles. Also, please take a look at the list of 7 glycidol manufacturers and their company rankings. Here are the top-ranked glycidol companies as of December, 2024: 1.MilliporeSigma, 2.Biosynth, 3.Blue Bear Chemicals.
Table of Contents
Glycidol (C3H6O2) is an organic compound containing both an epoxide and a hydroxyl group. Also known as oxiranylmethanol and 2,3-epoxy-1-propanol, it is a colorless to pale yellow liquid with a slight viscosity and a pungent odor.
Glycidol is used as a reactive diluent for epoxy and alkyd resins, a stabilizer for chlorinated organic compounds, a modifier for synthetic resins, and in dyeability modifications for dyes. It's also used in organic synthesis and as a raw material for various types of epoxy resin precursors.
Glycidol has a melting point of -65.2°F (-54°C) and decomposes thermally before boiling at 324°F (162°C). It is insoluble in aliphatic hydrocarbons but soluble in most organic solvents, including water, ethanol, ether, and benzene. Its flash point is 161.6°F (72°C) and its density is 1.112 g/ml.
Glycidol can be synthesized by reacting allyl alcohol with peracetic acid or hydrogen peroxide. The reaction yields glycidol along with acetic acid or water, respectively. The primary raw material, allyl alcohol, is derived from propylene.
Exposure to glycidol can irritate eyes, skin, and mucous membranes, and affect the central nervous system. It poses risks of pulmonary edema, pneumonia, and skin sensitization upon long-term exposure. Protective masks, glasses, gloves, and clothing are recommended when handling it.
Glycidol decomposes in contact with strong acids, bases, salts, and metals, posing fire or explosion risks. It may corrode plastics and rubber.
Glycidol is classified as a probable carcinogen (Group 2A). Concerns have been raised regarding its presence in glycidol fatty acid esters in cooking oils, leading to voluntary recalls due to the potential health risks.
*Including some distributors, etc.
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Pharmaffiliates, established in 2001 and located in Gurgaon, India, is a manufacturer of pharmaceutical standards and services. The company provides Certified Reference Standards (CRS) used in analytical methods, as well as drug delivery systems like tablets, capsules, injectables, and deuterated compounds that aid in research and development, studying drug metabolism and pharmacokinetics. Pharmaffiliates also offers various services to the pharmaceutical industry, including custom synthesis, analytical research, stability studies, and formulation development.
Biosynth is a Swiss manufacturer of life science reagents established in 1966 and headquartered in Staad. The company sources and manufactures biochemical products such as carbohydrates, nucleosides, and enzyme substrates, as well as various peptides and biologics. They also operate as a contract manufacturer offering custom synthesis and manufacturing services for their clients in the pharmaceutical, diagnostic, food, and agrochemical sectors. Biosynth has regional sales offices and specialized facilities in Europe and North America, including in the Netherlands, United Kingdom, and United States.
Toronto Research Chemicals Inc., founded in 1982 and based in Toronto, Canada, is a manufacturer of biochemicals and is a subsidiary of LGC Standards. The ISO 9001-certified company has an extensive catalog of over 350,000 products, including metabolites, impurities, and natural products APIs, which are used in several applications like environmental analysis, forensic science, and medicinal R&D. The company supports the scientific community across more than 120 countries and has 19 production laboratories. In 2019, it was bought by LGC, which provides components to customers in the pharmaceutical, clinical diagnostics, and food markets, among others.
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
Alfa Aesar is based in Lancashire, United Kingdom. Alfa Aesar is part of Thermo Fisher Scientific, is a manufacturer and supplier of chemicals, metals, and life science products for research and development. Alfa Aesar’s product lines include chemicals, life science, materials & metals, catalysts, and analytical & lab ware. Chemical offerings include inorganic compounds, organic compounds, organometallic, and solvents. Life sciences include biotechnology products, cellular & molecular biology, genomics, and immunology. Materials & metal include alloys, carbon, etchants, and more. Catalysts include ferrocenes, fuel cell products, and precious metals & catalysts. Alfa Aesar also offers custom manufacturing options.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | MilliporeSigma |
35.9%
|
| 2 | Biosynth |
25.6%
|
| 3 | Blue Bear Chemicals |
15.4%
|
| 4 | Cymaris Labs |
7.7%
|
| 5 | Alfa Aesar, Thermo Fisher Scientific. |
7.7%
|
| 6 | Pharmaffiliates |
5.1%
|
| 7 | Toronto Research Chemicals |
2.6%
|
Derivation Method
The ranking is calculated based on the click share within the glycidol page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
United States of America
|
1 | 16.7% |
|
India
|
1 | 16.7% |
|
Switzerland
|
1 | 16.7% |
|
Canada
|
1 | 16.7% |
|
United Kingdom
|
1 | 16.7% |
Netherlands
|
1 | 16.7% |
