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This section provides an overview for erythritol as well as their applications and principles. Also, please take a look at the list of 10 erythritol manufacturers and their company rankings. Here are the top-ranked erythritol companies as of December, 2024: 1.United States Biological, 2.Alfa Chemistry, 3.Apura Ingredients.
Table of Contents
Figure 1. Basic Information on Erythritol
Erythritol is a natural sugar alcohol with the chemical formula C4H10O4.
Examples of natural sugar alcohols other than erythritol include xylitol and sorbitol. Erythritol is found in fruits and mushrooms, as well as in fermented foods such as wine, soy sauce, sake, and miso.
Industrially, it can be produced from corn or wheat starch by fermentation with yeast. Its sweetness level is about 75-80% that of sugar. It is recognized as having zero calories under the Ministry of Health and Welfare's Energy Evaluation Act.
Erythritol has almost no calories and is effective in reducing obesity and blood sugar levels when substituted for sugar. Therefore, it is mainly used as an alternative sweetener to sugar.
Examples of common foods containing erythritol include candy, gum, and soft drinks. It can be used as a specific health food to reduce the occurrence of tooth decay or as a sweetener in foods for the sick, such as diabetics.
Furthermore, because of its heat-dissipating effect, erythritol is also used as a cosmetic ingredient in lotions and other moisturizing preparations.
Erythritol has a melting point of 121°C and a boiling point of 329-331°C. It is a colorless solid. Erythritol absorbs heat by dissolution and has a strong cooling effect.
Erythritol is expressed as HO(CH2)(CHOH)2(CH2)OH. Its molar mass is 122.12 g/mol and its density is 1.45 g/cm3.
Industrially, erythritol is first obtained from corn by hydrolysis of starch to obtain glucose. The glucose is then fermented by Candida magnoliae, Aureobasidium, Moniliella tomentosa var. pollinis, and other strains of bacteria. Erythritol can be produced by fermentation with
Genetically engineered mutants of Yarrowia lipolytica can produce erythritol by fermentation. Using glycerol as a carbon source, the yield can be increased up to 62% by high osmotic pressure.
Figure 2. Isomers of Erythritol
Threitol is a diastereomer of erythritol. It is a four-carbon sugar alcohol with the chemical formula C4H10O4. It is mainly used as a synthetic intermediate for various compounds. It has a melting point of 88-90°C, a boiling point of 331°C, and a density of 1.0151 g/cm3.
In vivo, threitol is found in the edible mushroom, Naratake (Armillaria mellea), which has a density of 1.0151 g/cm3. It is also present in Alaskan beetles (Upis ceramboides) and can be used as a cryoprotectant (anti-freeze).
Figure 3. Related Compounds of Erythritol
Pentaerythritol, like erythritol, is a tetravalent alcohol classified as a sugar alcohol. Industrially, it can be used as a raw material for rosin esters, synthetic lubricants, alkyd resins, and explosives.
Erythritol tetranitrate is made by nitration of erythritol with a mixture of concentrated sulfuric acid and nitrate or with a mixture of sulfuric acid and nitric acid. Similar to the high-performance explosive penthrite, it is an explosive compound sensitive to friction and shock. It is used in mixtures with other explosives and should be handled with care as it readily explodes.
*Including some distributors, etc.
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United States Biological, located in Salem, Massachusetts, is a manufacturer and supplier of life science research products. Its product offerings include biochemicals, antibodies, and molecular biology kits. The company’s products are used in various fields such as genomic research, biotechnology, and pharmaceutical development. Products are available from affordable research quantities to larger bulk amounts for process development and production. Its customer base comprises pharmaceutical and biotechnology companies both in the US and overseas.
Wego Chemical Group was founded in 1978 and headquartered in Great Neck, New York. WEGO is a full-service supplier and distributor of chemicals, minerals, and other raw materials to clients around the world. Markets and segments include agriculture & animal care, chemical & material manufacturing, construction & building materials, electronics, food & beverage, “household, industrial & institutional”, mining, oil & gas, personal care & pharmaceutical, paper & packaging, surface treatment, textiles, and water treatment.
Univar Solutions is a distributor and supplier of chemicals and ingredients since 1924 and are headquartered in Downers Grove, Illinois. The company provides a wide range of chemicals to customers and extends its value-added services to suppliers. The services include data sharing, digital marketing, lab and formulation capabilities, and more. As providers of chemicals their inventory is limitless with stocks of acids, enzymes, oxides, silicates, additives, and other ingredients and they offer packaging, product development, and custom blending besides the supplies. Overall industries like Food, Agriculture, Mining, Home and Industrial Cleaning, Pharmaceuticals, and lots more benefit from Univar Solutions.
Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
Mitsubishi Chemical Corporation was founded in 1933 and has a head office in Tokyo, Japan. Mitsubishi Chemical Corporation provides products including chemicals, industrial gases, and health care products to customers globally. Mitsubishi Chemical Group’s performance products division manufactures and distributes. functional food materials, electronic and electrical components, specialty chemicals, and other products. Mitsubishi Chemical health care products include pharmaceuticals, drug discovery solutions, diagnostic reagents, and instruments for medical use. Mitsubishi Chemical Corporation also provides other services such as engineering, information systems, logistics, and consulting.
Alfa Chemistry, founded in the year 2015 is based in New York, USA as a biotechnology company and manufacturer of graphene materials. Their product portfolio includes graphene oxide, CVD graphene film, graphene modification services, graphene series, graphene-like material, carbon nanomaterials, quantum dots, upcoming nanoparticles, and graphene transfer services. The company also provides services in custom manufacturing, and graphene analysis with quality assurance. The products are used in various industries which include energy, digital electronics, environment, textile, coating, and biomedical science.
Merck, started in 1668 and based in Darmstadt, Germany, is a supplier of solutions and services for research, development, and manufacture of pharmaceutical and biotechnological drug therapies. The company serves the life science industry and has a broad portfolio of 300,000 products, including biopharmaceutical manufacturing, industrial microbiology, reagent, life science research, and water purification products. It is available in 66 countries, brings together six brands, and has several ISO certifications, including ISO 13485, ISO 14001, ISO 13485, and ISO 50001.
BOC Sciences is headquartered in Shirley, New York as a brand of BOCSCI Inc. The company is a developer, manufacturer, marketer, and distributor of premium chemicals, emphasizing small molecule synthesis, biosynthesis, purification, and characterization used in academia, pharmaceuticals, biotech, CDMO, material sciences, and agriculture industries, supporting research and production. The company’s products include thousands of inhibitors, nucleotides, metabolites, and isotope-labeled products. The company offers custom synthesis and manufacturing, analytical services, antibody-drug conjugate development, and strain engineering and fermentation services.
ChemPoint, established in 1999 and a subsidiary of Univar Solutions Inc., is a fine and specialty chemical distributor headquartered in Bellevue, Washington. The company runs ChemPoint, a personalized e-distribution platform that enables the marketing and sales of specialty and fine chemicals in North America, Europe, the Middle East, and Africa. The platform features MarketConnect, a web-based tool that offers market transparency to customers and allows producers to review sales processes. ChemPoint offers a diverse range of specialty chemical products, including adhesives, lubricating fluids, polymers, sealants, and thermoplastics.
Apura Ingredients is a specialized ingredient supplier headquartered in California, the United States. Established in 2016, the company caters to diverse industries such as food and beverage, pharmaceuticals, and cosmetics, among others. It offers a comprehensive portfolio of ingredients, including flavorings, sweeteners, flavor modulators, and functional additives for all kind of flavors. These ingredients and materials enhance the taste, texture, and nutritional profile of various products, while also aiming to reduce health risks related to traditional ingredients.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | United States Biological |
24.9%
|
| 2 | Alfa Chemistry |
12.9%
|
| 3 | Apura Ingredients |
11.6%
|
| 4 | Merck |
10.0%
|
| 5 | Univar Solutions Inc. |
8.0%
|
| 6 | Wego Chemical Group Inc |
7.6%
|
| 7 | KANTO CHEMICAL CO.,INC. |
7.2%
|
| 8 | Mitsubishi Chemical Corporation |
6.8%
|
| 9 | BOC Sciences |
6.4%
|
| 10 | ChemPoint |
4.4%
|
Derivation Method
The ranking is calculated based on the click share within the erythritol page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
United States of America
|
3 | 50.0% |
|
Japan
|
2 | 33.3% |
| United States | 1 | 16.7% |
