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This section provides an overview for perchloric acid as well as their applications and principles. Also, please take a look at the list of 11 perchloric acid manufacturers and their company rankings. Here are the top-ranked perchloric acid companies as of December, 2024: 1.PENTA Chemicals, 2.Calibre Chemicals Pvt. Ltd., 3.GFS Chemicals, Inc..
Table of Contents
Perchloric acid, a halogenated acid with the formula HClO4, is known for its strong oxidizing properties. It is a colorless, fuming liquid at room temperature, typically available in 60-70% aqueous solutions due to its high hazard levels. It has a CAS number of 7601-90-3 and a molecular weight of 100.46.
Perchloric acid serves as an analytical reagent, particularly in ion exchange chromatography, and as a catalyst in organic synthesis. It is also used for dissolving metals, alloys, ores, and in the production of perchlorates like ammonium perchlorate, a component in rocket and missile propellants. Its applications extend to propellants, air bags, fireworks, and the electropolishing of metals.
Due to its high oxidizing power, perchloric acid is crucial for the decomposition of specimens with high organic content. It is always used alongside nitric acid to prevent explosions when in contact with organic materials. Additionally, it adjusts the dissociation pattern in ion exchange chromatography, influencing the retention time of substances.
Perchlorates, utilized in explosives and as oxidizing agents, are produced using perchloric acid. Ammonium perchlorate, specifically, is synthesized by reacting perchloric acid with ammonia, resulting in a substance used in rocket propellants.
As a strong acid, perchloric acid poses risks of explosion when heated or mixed with organic matter. It is classified under several GHS categories, including Oxidizing Liquid Category 1 and Corrosive to Metals Category 1, indicating its potential for causing fire, explosion, and metal corrosion. It also poses serious health risks, including acute toxicity, skin and eye damage, suspected carcinogenicity, reproductive toxicity, and specific target organ toxicity.
For safety, perchloric acid should be stored in glass or polyethylene containers, away from direct sunlight, at room temperature, and in a well-ventilated area to minimize risks.
Due to its corrosive nature, perchloric acid requires the use of protective equipment, such as gloves and glasses, and should be handled in well-ventilated areas to avoid respiratory irritation.
Perchloric acid, with a pKa of -10, is the most acidic of the chlorine oxoacids, reflecting the increased stability of its chlorate ion upon proton dissociation. This high acidity makes it comparable to other strong acids like nitric and sulfuric acid.
*Including some distributors, etc.
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Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
Junsei Chemical Co. Ltd., established in 1948 and headquartered in Tokyo, Japan, is a manufacturer of chemical reagents and chemical products, including commissioned synthesis of chemical products. Some of the products it makes include Sodium chloride solution, concentrated glycerin, calcium chloride, ascorbic acid, and nitric acid. The chemical products have a wide range of applications and can be used in pathological examination, as food additives, for analysis, and in the pharmaceutical industry. All its plants, including its research institute, are ISO4001 and ISO9001 certified, while its Saitama and Ibaraki plants are equipped with buildings that comply with GMP.
Kishida Chemical Co. Ltd., established in 1924 and headquartered in Osaka, Japan, is a manufacturer of reagents and high-purity chemicals and also does drug discovery support activities. Its product portfolio includes fine chemicals, research chemicals, ionic liquid, organic micro-analytical reagents, and chemical reagents for analysis. The products support several industries, including reagent business, battery material, drug discovery, and life science. The company is ISO 14001 certified and supplies several companies worldwide, including Meterion Advanced Chemicals Inc., Acros Organics, ChemBridge Corporation, Decon Laboratories, and InerBioScreen Ltd.
Alpha Chemika, founded in 1989 and based in Mumbai, India, is a manufacturer, supplier of laboratory reagents and fine chemicals. Their products are used in multiple industries, including pharmaceutical, chemical, biotechnology, and environmental. Their product portfolio ranges from chemicals such as Silver Nitrate, Perchloric Acid, and Lanthanum Acetate to laboratory tools and equipment such as Air Inlet Tubes, Air Inlet Tubes, and Optical Components. Alpha Chemika has been able to obtain ISO 9001:2000 certification.
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
PENTA Chemicals, established in 1990 and headquartered in Prague, Czech Republic, is a manufacturer and supplier of pure, laboratory, pharmaceutical, and special chemicals. The company offers a wide array of organic and inorganic chemicals in significant quantities, varying in quality from technical to pure, to A.G. and ACS standards. Among their products are acetaldehyde, acetamide, bromine, brilliant green, and white spirit. The company's commitment is underscored by numerous awards and certificates, including ISO 9001, ISO 14001, and the Responsible Care certificate for conscientious business practices within the chemical industry.
Calibre Chemicals Pvt. Ltd. was founded in 1984 in Mumbai, Maharashtra, India, as a manufacturer of specialty chemical products. The company specializes in the production of products including ammonium perchlorate, sodium persulfate, copper iodide, perchloric acid, potassium bromide, sodium iodate, and trimethylsulfoxonium iodide (TMSI), among others. These products serve as catalysts in chemical reactions, strong acids, and components in laboratory reagents. They also act as antiseptics in wound disinfection, provide iodine in nutritional supplements, and serve as reagents in chemical synthesis. Their adaptable applications span across industries such as pharmaceuticals, chemicals, materials synthesis, and research and development.
Prasol Chemicals Limited., founded in 1992 and headquartered in Mumbai, India, is a manufacturer of acetone & phosphorous based speciality chemicals. The company initially began manufacturing phosphorous-based chemicals and later diversified into acetone-based chemistry, creating an integrated value chain across its product line. The majority of its products consist of acetone and phosphorous derivatives, which find their end uses in pharmaceuticals, agrochemicals, and the home and personal care segments. The company has a government of India certified export House and a global distribution network across Asia, North America and the European Union.
GFS Chemicals was founded in 1928 and is based in Columbus, Ohio. GFS Chemicals is an ISO 9001:2015 certified manufacturer as well as a supplier of specialty and fine chemicals, serving customers worldwide. GFS serves an array of industries including pharmaceutical, electronics, energy, fragrances, agrichemical, and specialty polymers. GFS Chemicals supplies over 8,600 chemicals in the United States, available in both small and large quantities. GFS Chemicals also offers Karl Fischer reagents, PPT/PPB trace analysis grade acids, turbidity standards, and other high-quality materials.
Nacalai Tesque Inc., founded in 1846 and headquartered in Kyoto, Japan, is a manufacturer of research chemicals, fine chemicals, diagnostics, and the related instruments. Some of its products include cytokines, nucleic acid electrophoresis, cell dissociation reagents, and sialic acid-related products, and it also offers custom and bulk service for bulk reagents and cell culture media. The company has more than 50 domestic distributors and several worldwide, including Asia, the Middle East, Oceania, Europe, and Africa. It is ISO 9001 and ISO 9002 certified, while the Kyoto South brand and Tesque factory are ISO 14001 certified.
Founded in 1981, Central Drug House Ltd. serves the scientific community via manufacturing and marketing a library of over 9,000 products to laboratory fine chemicals and dehydrated culture media with emphasis on purity and service. Examples are acids & bases, adsorbents, disinfectants, indicator papers, oils, and solvents. CDH provides bio chemicals, research chemicals, laboratory reagents, various solvents, stains & indicators, and dehydrated culture media. CDH is ISO 9001 certified and CDHs’ products are in compliance with specifications of IP, BP, USP, and EP standards.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | PENTA Chemicals |
21.7%
|
| 2 | Calibre Chemicals Pvt. Ltd. |
15.9%
|
| 3 | GFS Chemicals, Inc. |
14.5%
|
| 4 | MilliporeSigma |
10.1%
|
| 5 | Junsei Chemical Co.,Ltd. |
8.7%
|
| 6 | Central Drug House |
7.2%
|
| 7 | Kishida Chemical Co.,Ltd. |
5.8%
|
| 8 | Prasol Chemicals Limited. |
4.3%
|
| 9 | KANTO CHEMICAL CO.,INC. |
4.3%
|
| 10 | nacalai |
4.3%
|
Derivation Method
The ranking is calculated based on the click share within the perchloric acid page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
Japan
|
4 | 66.7% |
|
India
|
2 | 33.3% |
