All Categories
History
This section provides an overview for hydrogen bromide as well as their applications and principles. Also, please take a look at the list of 39 hydrogen bromide manufacturers and their company rankings. Here are the top-ranked hydrogen bromide companies as of December, 2024: 1.Synthetika Chemicals, LLC, 2.SimSon Pharma Limited, 3.Kishida Chemical Co.,Ltd..
Table of Contents
Hydrogen bromide is a compound of bromine and hydrogen, a colorless gas with a pungent odor.
Its official name is hydrogen bromide, which is characterized by the white smoke it produces when exposed to air moisture. Hydrogen bromide is toxic and can damage the mucous membranes of the eyes and bronchial tubes and cause breathing difficulties.
Hydrogen bromide is used as a raw material for synthesizing pharmaceuticals, hydrobromic acid, and various bromides, as well as a general-purpose reagent. In the chemical industry, it is used as an alkylation catalyst and reducing agent.
Additionally, hydrogen bromide serves as a high-quality semiconductor material gas and can be used as an etching or cleaning gas. Hydrobromic acid, an aqueous solution of hydrogen bromide, is an important chemical used as a catalyst in the production of terephthalic acid, a raw material for polyester fiber, and as a raw material for various bromates and alkyl bromides.
Hydrogen bromide is corrosive and nonflammable. It has a density of 3.307 g/L, a melting point of -124° F (-86.80°C), and a boiling point of -87.48° F (-66.38°C).
As one of the halogenated hydrogens, it is a compound composed of hydrogen and bromine. Hydrogen bromide is a linear molecule with the chemical formula HBr and a molar mass of 80.912. Under low-temperature conditions, hydrogen bromide will form crystals of hydrate.
Hydrogen bromide is readily soluble in organic solvents with oxygen, such as ethanol and acetone. It is also well soluble in water, and its aqueous solution is a strong acid. The aqueous solution of hydrogen bromide is called hydrobromic acid. 47.63% hydrobromic acid is an azeotrope with a boiling point of 255.7° F (124.3°C).
A similar azeotrope, 48%, is commonly used commercially and is designated as a deleterious substance, not for medicinal use. Its heat of dissolution in water is ΔH° = -85.15 kJ/mol, the largest among hydrogen halides. It is a strong monovalent acid with properties similar to hydrochloric acid and is easily oxidized.
For example, it can be oxidized by air or decomposed by light to liberate bromine, which gives it a yellowish color. Furthermore, hydrogen bromide's reducing effect is stronger than that of hydrogen chloride (HCl).
Hydrogen bromide is produced by the reaction of hydrogen and bromine over a catalyst. Hydrogen bromide can be obtained by reacting bromide with phosphoric acid or by allowing bromine to act on a mixture of red phosphorus and water.
Various other synthetic methods are available on a laboratory scale. An example is the bromination of tetralin. Anhydrous hydrogen bromide can also be obtained by refluxing triphenylphosphonium bromide (Ph3PH+Br-) in xylene and thermally decomposing it.
However, unlike hydrogen chloride and hydrochloric acid, the scale of production of hydrogen bromide and hydrobromic acid is small. Early production methods involved the reaction of hydrogen and bromine at temperatures as high as 392-752° F (200-400°C), usually using platinum or asbestos as a catalyst in industrial reactions.
Hydrogen bromide is used to produce bromoalkanes with alcohols. Bromoalkanes can also be obtained by the addition of hydrogen bromide to alkenes.
The addition of hydrogen bromide to alkynes yields bromoalkenes, usually with stereochemistry in the anti form. The addition of hydrogen bromide to haloalkenes follows Markovnikov's rule, yielding gem-dihaloalkanes.
Hydrogen bromide is also used in the synthesis of bromoacetals as well as in the ring-opening reactions of lactones and epoxides. Hydrogen bromide can be used as a catalyst in a wide variety of organic reactions.
*Including some distributors, etc.
Sort by Features
Sort by Area
Spectrum Chemical MFG Corp. was founded in 1971, is headquartered in New Brunswick, New Jersey, and has facilities in Gardena, California. Spectrum is a fine chemical manufacturing company with an emphasis on USP, NF, FCC, BP, EP, JP, and ACS grade products, and is ISO 9001:2015 certified. Spectrum primarily serves the analytical, biopharmaceutical, food & beverage, personal care, and pharmaceutical chemicals industries. Spectrum has 4 product segments which are chemicals, equipment, supplies, and safety.
Santa Cruz Biotechnology, Inc., established in 1991 and headquartered in Dallas, Texas, is an American manufacturer and supplier specializing in biological products for medical research. Initially providing antibodies to the research community, they expanded their offerings to include gene silencers like siRNA and shRNA (plasmid and lentiviral), targeting all known mouse and human genes. Over time, Santa Cruz Biotechnology provides over 175,000 research biochemicals under the brand ChemCruz, including protein-interacting inhibitors, substrates, and activators, tailored for studying protein functions. The company offers monoclonal primary antibodies, designed for various mammalian and non-mammalian protein targets, along with corresponding binding secondary antibodies.
Molekula Group, established in 2000, is a chemical manufacturer and distributor based in Darlington, United Kingdom, supported by additional offices and warehouses in Germany, Italy, China, and the United States. The company operates two British subsidiaries, namely Scafell Organics Ltd, which manufactures fine organic chemicals, and Sherman Chemicals Ltd, which provides custom solutions across industries. The company adheres to ISO 9001:2015 standards and offers a diverse range of over 4,500 products. Their product portfolio includes analytical reagents, biochemicals, building blocks, organic and inorganic chemicals, as well as research organics and inorganics.
Parchem was founded in 1999 and headquartered in Rochelle, New York. Parchem is a distributor of industrial chemicals. Parchem serves nutritional, personal care, pharmaceutical, and specialty chemical industries. Parchem offerings include coatings, adhesives, elastomers, industrial products, petrochemicals, oleochemicals, plastics, rubber, nutritional supplements, cosmetics, consumer products, catalysts, metallic salts, rare earths, flavors & fragrances, industrial & institutional, textiles, other food-related chemicals, dyes, finishes, chemicals for aerospace, oil gas drilling chemicals, electronics, and pharmaceuticals.
Synthetika Chemicals, founded in 2021 and based in Gainesville, Florida, is a reagents supplier and does custom synthesis and consulting services. Some of the chemicals it stocks include chloroacetic acid, Iron (III) chloride, Hydrochloric acid, Iodomethane, and liquid mercury metal. The company sells its products worldwide and has capabilities ranging from 1 gram to 1 ton. The reagents are being used in over 30 countries with a 99.9% success delivery rate. The company also provides several payment options for its products, including Cash App, Venmo, Western Union, and multiple forms of cryptocurrency.
SimSon Pharma Limited, established in 2011 and headquartered in Mumbai, India, is a manufacturer and supplier of pharmaceutical reference materials. Their product range includes drug working standards, drug impurity standards, drug metabolites, and stable isotope labeled compounds. These provide a basis for comparison and validation, enabling pharmaceutical companies to produce safe and effective medications. The company's offerings serve specific purposes, such as calibrating analytical instruments and ensuring precise analytical results, identifying and quantifying impurities in drugs, understanding drug metabolism, and developing new drug therapies.
Toronto Research Chemicals Inc., founded in 1982 and based in Toronto, Canada, is a manufacturer of biochemicals and is a subsidiary of LGC Standards. The ISO 9001-certified company has an extensive catalog of over 350,000 products, including metabolites, impurities, and natural products APIs, which are used in several applications like environmental analysis, forensic science, and medicinal R&D. The company supports the scientific community across more than 120 countries and has 19 production laboratories. In 2019, it was bought by LGC, which provides components to customers in the pharmaceutical, clinical diagnostics, and food markets, among others.
Pharmaffiliates, established in 2001 and located in Gurgaon, India, is a manufacturer of pharmaceutical standards and services. The company provides Certified Reference Standards (CRS) used in analytical methods, as well as drug delivery systems like tablets, capsules, injectables, and deuterated compounds that aid in research and development, studying drug metabolism and pharmacokinetics. Pharmaffiliates also offers various services to the pharmaceutical industry, including custom synthesis, analytical research, stability studies, and formulation development.
Loba Chemie Pvt. Ltd. is a Mumbai-based manufacturer and supplier of laboratory and fine chemicals, catering to industries such as pharmaceuticals, food, research, hospitals, and universities since its establishment in 1975. Their product range includes pH indicators, biological stains, HPLC solvents, high purity acids, and tetrazolium salts and derivatives. These products serve various applications like pH testing, cell and tissue staining, chemical separation, and pharmaceutical manufacturing. The company has several certifications, such as ISO/IEC 17025:2017 and ISO 9001:2015.
Hefei Home Sunshine Pharmaceutical Technology Co., Ltd, established in 2013 and headquartered in Hefei City, China, is a manufacturer specializing in both standard and custom chemical synthesis. With manufacturing facilities in Anhui, Jiangsu, Zhejiang, and Inner Mongolia, Home Sunshine Pharma offers a range of products, including active pharmaceutical ingredients (APIs), intermediates, fine chemicals, coenzymes, and nucleotides. As an ISO 9001:2015 certified company, Home Sunshine Pharma serves research institutions, universities, and industries in Europe, America, and Southeast Asia with their chemical products.
Axiom Chemicals Pvt. Ltd., is a manufacturer & supplier of Chemical Products from, Gujarat, India since 2011. They produce various chemical compounds for commercial and industrial use such as the pharma intermediate range which includes Nickel Bromide, Calcium Citrate, Boric Acid, and more. There are also Lithium, Zinc, Bromine, Calcium, and Iodine compounds available, along with Phenothiazine Compound which is used in chemical manufacturing as a stabilizer or inhibitor. These chemicals have uses in the air & gas treatment plants, the construction industry, biotechnological processes, and for the manufacture of Ceramics.
Apollo Scientific Ltd, a subsidiary of Japan’s Central Glass Europe Limited, is a research chemicals manufacturer and supplier founded in 1993 and headquartered in Bredbury, United Kingdom. Performing chemical syntheses in their Manchester-based laboratories, Apollo Scientific offers a selection of over 100,000 chemical products, from fluorinated compounds to non-fluorinated building blocks, for research and industry applications. Their life science products include antibiotics and buffers, as well as customized products for stem cell, molecular biology, and proteomics research. Additionally, Apollo Scientific offers spectroscopy products, such as consumables for infrared (IR) and nuclear magnetic resonance (NMR) spectroscopy, as well as mass spectrometry standards.
Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
Junsei Chemical Co. Ltd., established in 1948 and headquartered in Tokyo, Japan, is a manufacturer of chemical reagents and chemical products, including commissioned synthesis of chemical products. Some of the products it makes include Sodium chloride solution, concentrated glycerin, calcium chloride, ascorbic acid, and nitric acid. The chemical products have a wide range of applications and can be used in pathological examination, as food additives, for analysis, and in the pharmaceutical industry. All its plants, including its research institute, are ISO4001 and ISO9001 certified, while its Saitama and Ibaraki plants are equipped with buildings that comply with GMP.
Kishida Chemical Co. Ltd., established in 1924 and headquartered in Osaka, Japan, is a manufacturer of reagents and high-purity chemicals and also does drug discovery support activities. Its product portfolio includes fine chemicals, research chemicals, ionic liquid, organic micro-analytical reagents, and chemical reagents for analysis. The products support several industries, including reagent business, battery material, drug discovery, and life science. The company is ISO 14001 certified and supplies several companies worldwide, including Meterion Advanced Chemicals Inc., Acros Organics, ChemBridge Corporation, Decon Laboratories, and InerBioScreen Ltd.
Biosynth is a Swiss manufacturer of life science reagents established in 1966 and headquartered in Staad. The company sources and manufactures biochemical products such as carbohydrates, nucleosides, and enzyme substrates, as well as various peptides and biologics. They also operate as a contract manufacturer offering custom synthesis and manufacturing services for their clients in the pharmaceutical, diagnostic, food, and agrochemical sectors. Biosynth has regional sales offices and specialized facilities in Europe and North America, including in the Netherlands, United Kingdom, and United States.
FujiFilm Wako Pure Chemical Corporation, founded in 1922 and headquartered in Osaka, Japan, is a manufacturer of laboratory chemicals, specialty chemicals, and clinical diagnostic reagents. The company has three business domains, namely laboratory chemicals, specialty chemicals, and clinical diagnostic reagents, and some of its products include biochemistry reagents, blood transfusion test drugs, battery materials, polymer-related materials, and general reagents. The products are useful in various fields, including electronic, cosmetic, polymeric, pharmaceutical, and medical care. It acquired Sibayagi Co. Ltd. in 2015 and provides custom manufacturing to meet customer requirements.
Air Liquide UK Ltd. is a manufacturer and supplier of industrial gases and equipment that was established in 1902 and is headquartered in Newfield, Stevenage, Hertfordshire, UK. The company produces a wide range of industrial gases, including pure gases, gas mixtures, equipment and CO2 equipment. Its products, such as Oxygen, Nitrogen, Argon, Hydrogen, and Helium, are used by a number of industries including engine emission testing, industrial emissions and environmental monitoring, oil and gas, combustion testing, life sciences and health and safety industries. The company also provides a range of services, including gas supply, gas blending, and gas equipment rental.
Resonac Corporation is a Japanese chemical manufacturer and supplier, catering to various industries was established in June 1939. Resonac Corporation has developed expertise in electronics, mobility, high-performance materials, olefins and derivatives, basic chemicals, graphite, device solutions, and life sciences. Serving a diverse range of industries, their product portfolio includes inorganics, aluminum, electronics, chemicals, and inorganic materials. With its headquarters in Tokyo, Japan, the company provides innovative solutions and products tailored to diverse customer needs. Resonac Corporation is recognized for its advanced technologies in the industry.
TCI America (TCI) was founded in 1946 and is a worldwide manufacturer of specialty organic chemicals. The company produces organic laboratory chemicals as well as pharmaceutical, cosmetic, and functional materials. TCI’s product segments include Chemistry, Life Science, Materials Science, Analytical Chemistry, and Custom & Bulk. For materials science, the company manufactures battery materials, nanocarbon materials, and magnetic materials. For life sciences, the company produces antibodies, reagents, and chemicals for cancer research. The company produces HLC, NMR, various chemicals, and resins and media for analytical chemistry.
Axiom Corporation, founded in 2014 in Antwerpen, Belgium, is a supplier and manufacturer of specialty organic and inorganic chemicals and derivatives. Products offered by the company include ammonium bromide, calcium iodide anhydrous, and copper sulfate. These are commonly used in plastic, agriculture, construction, cosmetics, and water treatment industries. The company's manufacturing facility and laboratory have a monthly capacity of 45 tons of lithium compounds and 30 metric tons of organic derivatives.
Strem Chemicals, Inc, founded in 1964, is an American manufacturer and supplier of high-purity specialty chemicals and materials, based in Newburyport, Massachusetts. Acquired by Ascensus Specialties, another American chemical company in 2021, Strem offers a catalog of over 6,000 specialty products under the metal, inorganic, organometallic, and nanomaterial categories. Some of their diverse product offerings include metal catalysts for organic synthesis, metal carbonyls, metal organic chemical vapor deposition (MOCVD) and atomic layer deposition (ALD) precursors. Strem serves global customers, particularly academic, governmental, and industrial research and development laboratories. Their products find applications in various industries, including microelectronics, chemicals, petrochemicals, and pharmaceuticals.
Sumitomo Seika Chemicals Co. LTD., founded in 1944 and headquartered in Osaka, Japan, is a manufacturer of functional chemicals, water-absorbing resins, and specialty gases. Some of its products include Aqua Keep, a super-absorbent resin produced using polymerization technology, and Aqua Coke, a nonionic polyalkylene oxide-based resin with water-absorbent properties. These resins find applications in various areas, such as in disposable diapers and as coagulants for wastewater treatment. The company was initially established for the production and sale of fertilizer. However, in 1981, it embarked on an expansion into functional resins, chemicals, and electronic gas businesses.
Merck, started in 1668 and based in Darmstadt, Germany, is a supplier of solutions and services for research, development, and manufacture of pharmaceutical and biotechnological drug therapies. The company serves the life science industry and has a broad portfolio of 300,000 products, including biopharmaceutical manufacturing, industrial microbiology, reagent, life science research, and water purification products. It is available in 66 countries, brings together six brands, and has several ISO certifications, including ISO 13485, ISO 14001, ISO 13485, and ISO 50001.
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
Nacalai Tesque Inc., founded in 1846 and headquartered in Kyoto, Japan, is a manufacturer of research chemicals, fine chemicals, diagnostics, and the related instruments. Some of its products include cytokines, nucleic acid electrophoresis, cell dissociation reagents, and sialic acid-related products, and it also offers custom and bulk service for bulk reagents and cell culture media. The company has more than 50 domestic distributors and several worldwide, including Asia, the Middle East, Oceania, Europe, and Africa. It is ISO 9001 and ISO 9002 certified, while the Kyoto South brand and Tesque factory are ISO 14001 certified.
SIAD Group, founded in 1927 and headquartered in Bergamo, Lombardy, is an Italian manufacturer and distributor specializing in industrial gases, as well as engineering and healthcare products and services. The company's product offerings include gases and gas mixtures for various industries. For instance, SIAD supplies specialty gases like high purity gases and noble gases to the electronic, environmental, petrochemical, and pharmaceutical sectors. SIAD also offers a range of refrigerant gases for air conditioning systems. SIAD also operates subsidiaries, such as SIAD Macchine Impianti S.p.A., which builds air separation units (ASUs), and SIAD HEALTHCARE SpA, which offers medical gases, surgical devices, and more.
Alfa Aesar is based in Lancashire, United Kingdom. Alfa Aesar is part of Thermo Fisher Scientific, is a manufacturer and supplier of chemicals, metals, and life science products for research and development. Alfa Aesar’s product lines include chemicals, life science, materials & metals, catalysts, and analytical & lab ware. Chemical offerings include inorganic compounds, organic compounds, organometallic, and solvents. Life sciences include biotechnology products, cellular & molecular biology, genomics, and immunology. Materials & metal include alloys, carbon, etchants, and more. Catalysts include ferrocenes, fuel cell products, and precious metals & catalysts. Alfa Aesar also offers custom manufacturing options.
Merck Millipore, founded in 1954 and headquartered in Darmstadt, Germany, is a manufacturer, distributor, and supplier of life science products and services. Their diverse range of products finds applications in research, development, and manufacturing of biotechnological and pharmaceutical drug therapies. Some of their offerings include filters for removing contaminants from liquids and gases, chromatography columns for separating and analyzing complex mixtures, reagents used in various laboratory assays, antibodies for detecting and quantifying specific molecules, and cell culture media for growing and maintaining cells in culture. Their products and services are utilized significantly in the advancement of life sciences and drug development.
Shanghai Theorem Chemical Technology Co., Ltd., established in 1997, is a company located in Shanghai, China, is a manufacturing company specializing in researching and manufacturing chemical new materials and fine chemicals. The company offers new functional materials, surfactants, polyurethane chemicals, special isocyanates, extractants, and more. They have a product chain advantage and offer professional technical support, and stable production supply with authorized ISO9001 quality management system, ISO14001 environmental management system, as well as related certifications. Their manufacturing factory with a land area of 80,000 m2, has over 300 workers, 30 engineers, 7 production workshops.
Sisco Research Laboratories Pvt. Ltd. was established in 1975 and is headquartered in Mumbai, Maharashtra, India. The company manufactures highly complex reagents and biochemicals for public and private customers across industries with over 5000 products in different grades and packing sizes across product segments. The company’s 6 product categories are General Laboratory Chemicals & Solvents, Biochemicals & Specialty Fine Chemicals, Animal Cell Culture, Nanotechnology Products, Dehydrated Culture Media & Media Kits, and Biolit™ range of DNA and Protein tools.
Founded in 1981, Central Drug House Ltd. serves the scientific community via manufacturing and marketing a library of over 9,000 products to laboratory fine chemicals and dehydrated culture media with emphasis on purity and service. Examples are acids & bases, adsorbents, disinfectants, indicator papers, oils, and solvents. CDH provides bio chemicals, research chemicals, laboratory reagents, various solvents, stains & indicators, and dehydrated culture media. CDH is ISO 9001 certified and CDHs’ products are in compliance with specifications of IP, BP, USP, and EP standards.
Founded in Mumbai, India in 2006, Otto Chemie Pvt. Ltd. is an ISO 9001:2015 & GMP certified chemical manufacturing company and distributor. Otto Chemie serves customers in many industries including agriculture and food processing, pharmaceuticals, oil & gas, cement, as well as educational and R&D industries. Product offerings include antibiotics, amino acids, vitamins, detergents, ionic liquids, materials science compounds, labware, oil, metal & ceramic science compounds and tools, oils, reagents, solvents.
Echemi Digital Technology Co. Ltd., started in 2015 and based in Hong Kong, China, is a supplier of chemical raw materials through its B2B digital commerce platform. The company sells products such as propylene carbonate, adipic acid, and oseltamivir phosphate and serves over 100,000 buyers and over 20,000 suppliers in more than 190 countries worldwide. It also provides price and market analysis of over 500 raw materials per week in the areas of coatings, fine chemicals, and pharmaceuticals. It also covers food and nutrition and was ranked 55th in the 2022 ICIS top 100 chemical distributors.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | Synthetika Chemicals, LLC |
33.3%
|
| 2 | SimSon Pharma Limited |
9.5%
|
| 3 | Kishida Chemical Co.,Ltd. |
9.5%
|
| 4 | Oxford Instruments plc, UK |
4.8%
|
| 5 | CYMIT QUÍMICA S.L. |
4.8%
|
| 6 | ECHEMI |
4.8%
|
| 7 | Air Liquide UK Ltd |
4.8%
|
| 8 | Hefei Home Sunshine Pharmaceutical Technology Co., Ltd. |
4.8%
|
| 9 | Strem Chemicals, Inc |
4.8%
|
| 10 | Parchem |
4.8%
|
Derivation Method
The ranking is calculated based on the click share within the hydrogen bromide page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
Japan
|
8 | 25.8% |
|
India
|
7 | 22.6% |
|
United States of America
|
5 | 16.1% |
|
China
|
4 | 12.9% |
|
United Kingdom
|
3 | 9.7% |
|
Canada
|
1 | 3.2% |
|
Switzerland
|
1 | 3.2% |
|
Italy
|
1 | 3.2% |
Spain
|
1 | 3.2% |
2 products found
2 products
SUMITOMO SEIKA CHEMICALS CO.,LTD.
290+ people viewing
Standard Response
■ Grade ・ Pure/Pure-D synthetic reaction experiment, mixed gas raw material, qualitative analysis, etc. can be used for multiple purposes. ・ UHP,...
