This section provides an overview for thallium sulfate as well as their applications and principles. Also, please take a look at the list of 11 thallium sulfate manufacturers and their company rankings. Here are the top-ranked thallium sulfate companies as of November, 2024: 1.Pharmaffiliates, 2.SRL, 3.American Elements.
Table of Contents
Thallium sulfate is the sulfate salt of thallium.
It is a colorless crystalline powder with no taste or odor. It is soluble in water and ethanol and is also used in liquid form.
Thallium sulfate is classified as a deleterious substance and must be stored and used with care. It has acute and chronic toxicity, affecting the gastrointestinal tract, nervous system, respiratory organs, and kidneys when ingested orally.
It has also been shown to be toxic for reproduction, and may affect the development of testes and fetuses. Because of these toxic effects, thallium sulfate was used as a rat poison, but is no longer used.
Thallium sulfate was once used as a rat poison. Because it is soluble in water, it is easy to prepare poison baits, and since rats eat it without avoiding it, poison baits were prepared by adding a solution of thallium sulfate to the food preferred by rats.
Thallium sulfate is not excreted but accumulates in the body of rats, so even if an individual does not eat a lethal dose at once, it will die by continuous ingestion of the poisoned food. In addition, its reproductive toxicity suppresses the reproduction of rats and keeps the population low over the long term.
Rodenticides containing thallium sulfate were previously registered as pesticides, but the registration was revoked due to its high toxicity and low distribution volume. Since the pesticide registration of thallium sulfate expired, other ingredients such as zinc phosphide, coumarin, and difethialol have been used in rodenticides.
Thallium sulfate is the sulfate salt of thallium, with the chemical formula Tl2SO4. Thallium sulfate is a colorless crystal that is stable at room temperature, and when dissolved in water, it ionizes into thallium (univalent) and sulfate ions.
The raw material thallium is a group 13 metallic element that is recovered as a byproduct of the refining process of copper, lead, and zinc. Thallium exists mainly as a monovalent ion, but when oxidized, trivalent ions may be produced to form thallium oxide, etc.
The basic properties of thallium sulfate (molecular weight, specific gravity, and solubility) are as follows:
Thallium sulfate is toxic to humans. Ingestion due to accidents or incidents in the past has been reported to cause anorexia, vomiting, abdominal pain, bloody stools, etc., followed by abnormal limb perception, hallucinations, convulsions, tachycardia, hair loss, and other symptoms. In severe cases, death occurs due to kidney and central nervous system abnormalities and heart failure.
To prevent accidental ingestion, containers containing thallium sulfate must be clearly labeled with the name of the substance. Storing thallium sulfate in containers such as those used for food or handling it while eating or drinking increases the risk of accidental ingestion or ingestion and is very dangerous.
Since experiments on rats have confirmed that the original (unformulated pure product) of thallium sulfate is also percutaneous toxic, care must also be taken to avoid skin contact. Wear protective equipment such as nitrile gloves and protective glasses, and wash thoroughly with water if it adheres to the skin. If it gets into the eyes, rinse well under running water and seek medical attention.
When thallium sulfate is heated, it decomposes to produce fumes such as toxic thallium and sulfur oxides. Fumes are fine particles of evaporated or sublimated substances that condense in the air. Fumes are spread over a wide area as smoke or aerosols, so there is a risk of inhalation by workers. Thallium sulfate is also toxic in fumes, so if there is a risk that thallium sulfate may be heated in experiments, etc., measures such as handling it with ventilation in a draft are necessary.
Thallium sulfate reacts violently with oxidants to form oxides. The reaction heat during oxidation may produce toxic fumes, so care should be taken to store and use thallium sulfate in such a way that it does not come into contact with oxidants.
Thallium sulfate is toxic to wild birds and aquatic organisms, and must be prevented from leaking into the environment. When disposing of thallium sulfate, follow the standards set by the local government or outsource disposal to a specialized contractor.
*Including some distributors, etc.
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American Elements was founded in 1997 in California and currently has research and production facilities in Utah, Mexico, China, and the United Kingdom. AE manufactures and distributes advanced materials from a catalog of over 30,000 products for bulk industrial use as well as small scale laboratory use. AE also provides testing and analyses services including spectroscopy along with structural, thermal, and electrical analyses. AE holds sustainable development as a core corporate value and is committed to work to protect the health of the environment.
Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
Junsei Chemical Co. Ltd., established in 1948 and headquartered in Tokyo, Japan, is a manufacturer of chemical reagents and chemical products, including commissioned synthesis of chemical products. Some of the products it makes include Sodium chloride solution, concentrated glycerin, calcium chloride, ascorbic acid, and nitric acid. The chemical products have a wide range of applications and can be used in pathological examination, as food additives, for analysis, and in the pharmaceutical industry. All its plants, including its research institute, are ISO4001 and ISO9001 certified, while its Saitama and Ibaraki plants are equipped with buildings that comply with GMP.
Nanochemazone is a Canadian manufacturer and supplier of nanomaterials established in 2015. The company provides nanomaterial products for research and development as well as for industrial applications. They are also involved in all aspects of the business: manufacturing, research and development, processing, supplying and marketing of nanoscale, microscale, and metal nanopowder products at a global level. They have established close relationships with many research universities, national laboratories, nanotechnology-based companies, and nanomaterial suppliers such as Nanoshel, Nanorh, American Elements etc.
Pharmaffiliates, established in 2001 and located in Gurgaon, India, is a manufacturer of pharmaceutical standards and services. The company provides Certified Reference Standards (CRS) used in analytical methods, as well as drug delivery systems like tablets, capsules, injectables, and deuterated compounds that aid in research and development, studying drug metabolism and pharmacokinetics. Pharmaffiliates also offers various services to the pharmaceutical industry, including custom synthesis, analytical research, stability studies, and formulation development.
FujiFilm Wako Pure Chemical Corporation, founded in 1922 and headquartered in Osaka, Japan, is a manufacturer of laboratory chemicals, specialty chemicals, and clinical diagnostic reagents. The company has three business domains, namely laboratory chemicals, specialty chemicals, and clinical diagnostic reagents, and some of its products include biochemistry reagents, blood transfusion test drugs, battery materials, polymer-related materials, and general reagents. The products are useful in various fields, including electronic, cosmetic, polymeric, pharmaceutical, and medical care. It acquired Sibayagi Co. Ltd. in 2015 and provides custom manufacturing to meet customer requirements.
Merck, started in 1668 and based in Darmstadt, Germany, is a supplier of solutions and services for research, development, and manufacture of pharmaceutical and biotechnological drug therapies. The company serves the life science industry and has a broad portfolio of 300,000 products, including biopharmaceutical manufacturing, industrial microbiology, reagent, life science research, and water purification products. It is available in 66 countries, brings together six brands, and has several ISO certifications, including ISO 13485, ISO 14001, ISO 13485, and ISO 50001.
Nanoshel is an Indian manufacturer of engineered nanomaterials and nanocompounds that was established in 2005 as a subsidiary of Intelligent Materials Pvt Limited. Based in Sundran, Punjab, the company produces various quantum dots, carbon nanotubes, and nanopowders from different materials including metal and graphene. It also offers a range of organics as well as inorganics, such as nano-enhanced fertilizers, wafers, and nanoparticle dispersions. Nanoshel products are commonly used in the production of consumer electronics, as well as in the agriculture, biomedical, and energy industries.
Honeywell, founded in 1906, in Wabash, Indiana is manufacturer of automotive parts, building technologies, and performance and safety materials for aerospace, The company's product portfolio includes electronic guidance systems, cockpit instrumentation, lighting, automotive parts, and primary propulsion and secondary power turbine engines. The company serves industries such as Oil and Gas, Aerospace and Defense, Automotive and Transportation, Construction, and Power Generation. Their headquartere is located in Carolina and they have global sales offices and distributions channels.
Nacalai Tesque Inc., founded in 1846 and headquartered in Kyoto, Japan, is a manufacturer of research chemicals, fine chemicals, diagnostics, and the related instruments. Some of its products include cytokines, nucleic acid electrophoresis, cell dissociation reagents, and sialic acid-related products, and it also offers custom and bulk service for bulk reagents and cell culture media. The company has more than 50 domestic distributors and several worldwide, including Asia, the Middle East, Oceania, Europe, and Africa. It is ISO 9001 and ISO 9002 certified, while the Kyoto South brand and Tesque factory are ISO 14001 certified.
Sisco Research Laboratories Pvt. Ltd. was established in 1975 and is headquartered in Mumbai, Maharashtra, India. The company manufactures highly complex reagents and biochemicals for public and private customers across industries with over 5000 products in different grades and packing sizes across product segments. The company’s 6 product categories are General Laboratory Chemicals & Solvents, Biochemicals & Specialty Fine Chemicals, Animal Cell Culture, Nanotechnology Products, Dehydrated Culture Media & Media Kits, and Biolit™ range of DNA and Protein tools.
Ranking as of November 2024
Derivation MethodRank | Company | Click Share |
---|---|---|
1 | Pharmaffiliates |
24.4%
|
2 | SRL |
21.8%
|
3 | American Elements |
14.1%
|
4 | Nanochemazone |
7.7%
|
5 | nacalai |
7.7%
|
6 | Nanoshel |
6.4%
|
7 | Merck |
5.1%
|
8 | Honeywell |
3.8%
|
9 | FUJIFILM Wako Pure Chemical Corporation |
3.8%
|
10 | KANTO CHEMICAL CO.,INC. |
3.8%
|
Derivation Method
The ranking is calculated based on the click share within the thallium sulfate page as of November 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
Country | Number of Companies | Share (%) |
---|---|---|
Japan | 4 | 50.0% |
India | 2 | 25.0% |
United States of America | 1 | 12.5% |
Canada | 1 | 12.5% |