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This section provides an overview for methyl hesperidin as well as their applications and principles. Also, please take a look at the list of 10 methyl hesperidin manufacturers and their company rankings. Here are the top-ranked methyl hesperidin companies as of December, 2024: 1.Shaanxi GTL Biotech Co.,Ltd.
Table of Contents
Methyl hesperidin is a water-soluble form of hesperidin, a primary component of vitamin P, enhancing its application in various fields.
The IUPAC name is (2S)-2-(3,4-dimethoxyphenyl)-5-hydroxy-7- { [(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6- ( { [(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy} [methyl) oxan-2-yl] oxy} -3,4-dihydro-2H-1-benzopyran-4-one (English: (2S) -2- (3,4-dimethoxyphenyl) -5-hydroxy-7- [ (2S,3R,4S,5S,6R) -3,4,5-trihydroxy-6- [ [ (2R ,3R,4R,5R,6S) -3,4,5-trihydroxy-6-methyloxan-2-yl] oxymethyl] oxy-2,3-dihydrochromen-4-one).
As a flavonoid found in citrus fruits, hesperidin boasts physiological benefits, including supporting vitamin C effects, strengthening capillaries, and improving blood circulation. Its potential in antioxidant and antiallergic activities further underscores its versatility.
However, hesperidin's water insolubility challenges its direct use, paving the way for methyl hesperidin's development.
Methyl hesperidin, utilized in anti-aging cosmetics, targets melanin synthesis inhibition, glycation prevention, and blood flow enhancement. Its anti-glycation property is particularly noted for combating skin aging signs, thereby maintaining skin elasticity and transparency.
Furthermore, methyl hesperidin and vitamin C synergistically amplify each other's effects, whether applied orally or transdermally.
Beyond cosmetics, methyl hesperidin is beneficial in nutritional foods and dietary supplements, attributed to its comprehensive health-promoting properties.
With the chemical formula C29H36O15 and a molecular weight of 624.59, methyl hesperidin's solubility in water and dimethyl sulfoxide contrasts with its ethanol insolubility. Its CAS number is 11013-97-1.
This compound appears as a light yellow to brown crystalline solid, demonstrating its distinct physical characteristics.
The production of methyl hesperidin involves methylation, desalting, and lyophilization, resulting in its crystalline form.
Handling Precautions
To mitigate risks associated with its oxidizing nature, appropriate safety measures, including protective gear and handling practices, are recommended.
Utilize a draft chamber for safe use and ensure thorough post-use hygiene practices.
In Case of Fire
Address fire hazards with suitable extinguishers and firefighter equipment, mindful of potential toxic emissions.
Storage Recommendations
Emphasize secure, cool, and protected storage conditions to preserve methyl hesperidin's integrity.
*Including some distributors, etc.
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MedChemExpress (MCE), is headquartered in Monmouth Junction, New Jersey, and is a supplier of research chemicals and biochemicals for laboratory and scientific use. The company’s product range includes biochemical assay reagents, isotope-labeled compounds, inhibitory antibodies, recombinant proteins, and fluorescent dyes. These products are used in various biopharmaceutical research and development fields, including areas such as infection, cardiovascular diseases, neurodegenerative diseases, diabetes, and autoimmune diseases. The company is ISO 19001 certified and provides testing services within the ISO 17025 framework, offering bulk and custom product services and support for metrological traceability.
GlpBio Technology, established in 2016 and headquartered in Montclair, California, is a supplier of life science products covering 20 popular research fields, including epigenetics, neuroscience, and cancer. Its product portfolio has over 20,000 life science reagents, including biochemicals, tag peptides, bioactive peptides, amino acids, and nature products. Its main clients include clinical diagnostic laboratories, government agencies, research institutes, universities, and pharmaceutical companies. The company regularly increases its products to meet the latest research needs and provides custom organic synthesis and analytical services.
Santa Cruz Biotechnology, Inc., established in 1991 and headquartered in Dallas, Texas, is an American manufacturer and supplier specializing in biological products for medical research. Initially providing antibodies to the research community, they expanded their offerings to include gene silencers like siRNA and shRNA (plasmid and lentiviral), targeting all known mouse and human genes. Over time, Santa Cruz Biotechnology provides over 175,000 research biochemicals under the brand ChemCruz, including protein-interacting inhibitors, substrates, and activators, tailored for studying protein functions. The company offers monoclonal primary antibodies, designed for various mammalian and non-mammalian protein targets, along with corresponding binding secondary antibodies.
Alps Pharmaceutical Ind. Co. Ltd., established in 1947 and headquartered in Hida-shi, Japan, functions as a global pharmaceutical product manufacturer. Its product line comprises of active pharmaceutical ingredients (APIs), veterinary APIs, food additives, and feed additives. The company adopts a strategic warehousing approach, maintaining the Okamae warehouse with an extensive capacity of 8,000 tons for both products and raw materials. This robust supply chain strategy allows them to effectively hedge against risks related to weather-induced crop failures, market price fluctuations, and procurement challenges.
Shaanxi GTL Biotech Co., Ltd., established in 2017 and headquartered in Xi'an, China, is a manufacturer and supplier of botanical extracts and manufacturer of healthcare ingredients. The company specializes in producing a wide range of extracts derived from plants, herbs, and fruits for applications in the pharmaceutical, nutraceutical, and food industries. The company's products are utilized in the development of dietary supplements, functional foods, and pharmaceutical formulations. The company also supports universities and institutions with research and development materials.
Jigs Chemical was established in 1998 and is based in India with global offices in the USA, UK, Canada, and Australia. Jigs Chemical is a manufacturer, distributor, and marketing & sales provider for organizations in India, specializing in chemicals and active pharmaceutical ingredients for pharmaceutical, agriculture, ceramics, metal treatment, and other industries. Jigs Chemical helps facilitate international customers to obtain chemicals from India, providing import and export assistance. Jigs Chemical’s product catalog includes over 40000 active pharmaceutical ingredients, commonly called APIs, their respective intermediates, and other chemicals.
Founded in Mumbai, India in 2006, Otto Chemie Pvt. Ltd. is an ISO 9001:2015 & GMP certified chemical manufacturing company and distributor. Otto Chemie serves customers in many industries including agriculture and food processing, pharmaceuticals, oil & gas, cement, as well as educational and R&D industries. Product offerings include antibiotics, amino acids, vitamins, detergents, ionic liquids, materials science compounds, labware, oil, metal & ceramic science compounds and tools, oils, reagents, solvents.
Plamed Green Science Group, founded in China in 2013, is a supplier of natural cosmetic ingredients for sensitive skin. The company's product portfolio includes natural extracts for cosmetics, Ginger Oil and extract, and chemical cosmetics raw materials (arbutin). Its products are used in pharmaceuticals, biotechnology, agriculture, and environmental science. The company ensures that natural products are sourced, processed, and validated to meet the highest industry standards, providing researchers with accurate and reliable resources.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | Shaanxi GTL Biotech Co.,Ltd |
100.0%
|
Derivation Method
The ranking is calculated based on the click share within the methyl hesperidin page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
China
|
4 | 50.0% |
|
United States of America
|
3 | 37.5% |
|
India
|
1 | 12.5% |
