This section provides an overview for methanesulfonic acid as well as their applications and principles. Also, please take a look at the list of 14 methanesulfonic acid manufacturers and their company rankings. Here are the top-ranked methanesulfonic acid companies as of November, 2024: 1.FINAR, 2.Sinocompound, 3.Junsei Chemical Co.,Ltd..
Table of Contents
Methanesulfonic acid (CH3SO3H), also known as mesylic acid or MsOH, represents the simplest form of alkane sulfonic acids. This colorless, odorless, and strong organic acid stands out for its ease of handling and resistance to oxidation.
It dissolves readily in water, alcohol, and ether, while remaining insoluble in alkanes, benzene, and toluene. Notably, it exerts a strong corrosive impact on ferrous metals, copper, and lead.
Valued in the metal plating industry, methanesulfonic acid is chosen for its absence of hydrolysis reactions, capability to support high metal concentrations, and stability across a broad pH spectrum.
As a versatile organic acid, methanesulfonic acid serves a wide array of sectors, including pharmaceuticals, chemical synthesis, biofuel production, industrial cleaning, and metal surface processing in electronics manufacturing. Its biodegradability, non-oxidizing nature, and lack of color and odor render it an environmentally friendly choice over traditional acids like sulfuric, phosphoric, and acetic acids.
It's particularly favored as a phosphoric acid alternative in cleaning agents due to its lower environmental impact. Beyond these applications, methanesulfonic acid acts as a reducing agent in dyes and a water-repellent for textiles, showcasing its broad utility.
The esters derived from methanesulfonic acid, known as mesylates, play critical roles as alkylation reagents or leaving groups in chemical reactions.
This acid is a colorless, oily liquid characterized by a pungent smell. It is highly soluble in water, enabling the creation of concentrated solutions. Its compatibility with various organic solvents further broadens its industrial applicability.
Thermal stability and resistance to decomposition under heat make methanesulfonic acid a reliable proton source for acid-catalyzed reactions and dehydration processes.
These characteristics underpin its widespread use in organic synthesis and materials science, where its low oxidizing power facilitates selective reactions with functionally sensitive compounds.
With the molecular formula CH3SO3H, methanesulfonic acid features a sulfonic acid group attached to methane. It boasts a molecular weight of 96.1, a density of 1.4812 g/cm3, and operates within a melting point of 18°C and a boiling point of 167°C. Its CAS number is 75-75-2.
Industrial synthesis of methanesulfonic acid commonly employs the oxidation of dimethyl sulfide, among other techniques.
1. Oxidation of Dimethyl Sulfide: Utilizing strong oxidants like potassium permanganate or nitric acid to oxidize dimethyl sulfide yields methanesulfonic acid.
2. Sulfonation of Methane: Methane reacts with sulfur trioxide under specific conditions, although this method is less frequently used due to its demanding requirements.
A catalyzed reaction between sulfuric acid and methane at high temperatures also produces methanesulfonic acid, demonstrating the acid's diverse synthesis routes.
3. Reaction with Chloromethane: Chloromethane's reaction with concentrated sulfuric acid under controlled conditions further illustrates the acid's versatile production methods, resulting in methanesulfonic acid and hydrogen chloride.
*Including some distributors, etc.
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Varsal, founded in 1993 and located in Warminster, Pennsylvania, USA is a manufacturer of specialty chemicals and pharmaceutical intermediates. The company specializes in the production of sulfonyl chemicals like methanic sulfonic acid, trifluromethanic sulfonic acid, phosphorous chemicals, pharmaceutical intermediates, amino acids and industrial and speciality chemicals. The company also manufactures industrial lab instruments like Hollow Cathode Lamps, Deuterium Arc Lamps, Atomic Absorption Spectrometer Systems and W1900 Microwave Digestion Systems. The global headquarters of the company is located in the Philadelphia, USA metropolitan area and its key market regions are North and South America, European Union, and Asia Pacific.
Hydrite Chemical Co. was founded in 1929 in Brookfield, Wisconsin, as a manufacturer and supplier of chemicals. The company's product line comprises acetone, acetic acid, citric acid, formic acid, caustic soda, chlorine, and ammonium sulphate, among others. It offers expertise in food and dairy sanitation, food ingredients, organic processing, liquid sulfites, chemical manufacturing and distribution, water treatment, and foam control chemistry. The products increase the flavour of the food; the cleansers improve the standard of the food supply; and the chemistry increases the quality of the water. The company intends to serve the energy, agriculture, biofuels, graphic, and food industries.
Ibis Scientific is a supplier of analytical laboratory products and certified reference standards to Analysts. The company is based in Las Vagas, Nevada, United States, and is a major distributor for premium laboratory product manufacturers including Biotix. The company's core product lines include Sample Prep Products, Liquid Handling Products, Certified Reference Materials, and General Lab Products. Ibis Scientific's analytical instrument components and high-purity lab chemicals such as reagents serve pharmaceutical, petrochemical, and cannabis testing laboratories throughout North America.
Actylis is based in Port Washington, New York, USA, and is an ISO 13485-certified custom manufacturer of chemical compounds that was established in 1978 as a subsidiary of Aceto. The company mainly produces specialty chemical products for the pharmaceutical, biopharm, and agriscience sectors. These chemical products include cell culture ingredients, active pharmaceutical ingredients (APIs), and buffering salts. It also offers excipients, adenosine for cosmetic ingredients, and vitamins for nutritional supplements. The company operates internationally, with manufacturing facilities in Germany, the United Kingdom, and India. Some of its notable clients include Novartis, Nestlé, and Estée Lauder.
Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
Junsei Chemical Co. Ltd., established in 1948 and headquartered in Tokyo, Japan, is a manufacturer of chemical reagents and chemical products, including commissioned synthesis of chemical products. Some of the products it makes include Sodium chloride solution, concentrated glycerin, calcium chloride, ascorbic acid, and nitric acid. The chemical products have a wide range of applications and can be used in pathological examination, as food additives, for analysis, and in the pharmaceutical industry. All its plants, including its research institute, are ISO4001 and ISO9001 certified, while its Saitama and Ibaraki plants are equipped with buildings that comply with GMP.
Kishida Chemical Co. Ltd., established in 1924 and headquartered in Osaka, Japan, is a manufacturer of reagents and high-purity chemicals and also does drug discovery support activities. Its product portfolio includes fine chemicals, research chemicals, ionic liquid, organic micro-analytical reagents, and chemical reagents for analysis. The products support several industries, including reagent business, battery material, drug discovery, and life science. The company is ISO 14001 certified and supplies several companies worldwide, including Meterion Advanced Chemicals Inc., Acros Organics, ChemBridge Corporation, Decon Laboratories, and InerBioScreen Ltd.
Toronto Research Chemicals Inc., founded in 1982 and based in Toronto, Canada, is a manufacturer of biochemicals and is a subsidiary of LGC Standards. The ISO 9001-certified company has an extensive catalog of over 350,000 products, including metabolites, impurities, and natural products APIs, which are used in several applications like environmental analysis, forensic science, and medicinal R&D. The company supports the scientific community across more than 120 countries and has 19 production laboratories. In 2019, it was bought by LGC, which provides components to customers in the pharmaceutical, clinical diagnostics, and food markets, among others.
Sinocompound, established in 2008, in Zhangjiagang, Jiangsu, China, is a manufacturer of homogeneous catalysts and ligands. The company manufactures homogeneous catalysts, Buchwald products, ligands, and metallocene catalysts. The company also offers services like catalyst screening and SC synthesis. The company caters to organometallic chemistry and manufacturing sectors globally and the research departments of various universities around the world. With 47000 sq. metre of research and development centre, and 800 plus satisfied customers, the company is now known for its superior products and services. In 2019, the company acquired 66,000 sq. metres of land to launch its new production plant unit.
Biosynth is a Swiss manufacturer of life science reagents established in 1966 and headquartered in Staad. The company sources and manufactures biochemical products such as carbohydrates, nucleosides, and enzyme substrates, as well as various peptides and biologics. They also operate as a contract manufacturer offering custom synthesis and manufacturing services for their clients in the pharmaceutical, diagnostic, food, and agrochemical sectors. Biosynth has regional sales offices and specialized facilities in Europe and North America, including in the Netherlands, United Kingdom, and United States.
FINAR, founded in, Ahmedabad, Gujarat, in 1998 is a manufacturer of Laboratory Chemicals such as Pharmaceutical Excipients and Solvents, and Food Grade Additives. The company's product portfolio includes Dry solvents, AR/ACS reagents, FinSQ Food Grade Additives, Pharmaceutical Excipients, and Aqua Culture Chemicals. Their products are used in industries such as Food and Beverage, Pharmaceutical and Biotechnology, Chemical and Petrochemical, Environmental Testing and electronics. The company has a sales network across India and overseas in over 50 countries.
Merck, started in 1668 and based in Darmstadt, Germany, is a supplier of solutions and services for research, development, and manufacture of pharmaceutical and biotechnological drug therapies. The company serves the life science industry and has a broad portfolio of 300,000 products, including biopharmaceutical manufacturing, industrial microbiology, reagent, life science research, and water purification products. It is available in 66 countries, brings together six brands, and has several ISO certifications, including ISO 13485, ISO 14001, ISO 13485, and ISO 50001.
Nacalai Tesque Inc., founded in 1846 and headquartered in Kyoto, Japan, is a manufacturer of research chemicals, fine chemicals, diagnostics, and the related instruments. Some of its products include cytokines, nucleic acid electrophoresis, cell dissociation reagents, and sialic acid-related products, and it also offers custom and bulk service for bulk reagents and cell culture media. The company has more than 50 domestic distributors and several worldwide, including Asia, the Middle East, Oceania, Europe, and Africa. It is ISO 9001 and ISO 9002 certified, while the Kyoto South brand and Tesque factory are ISO 14001 certified.
MDPI was founded in 1996 and is based in Basel, Switzerland. The company is a pioneer in scholarly, open-access publishing, featuring 417 peer-reviewed journals and 9 conference journals with over 115,000 academic contributors. The company’s journals fall into 10 subjects including biology, economics, medicine, physical sciences, and public health. The company’s pear review system is a dingle-blind assessment with at least two independent reviewers, followed by a final decision of acceptance or rejection by the editor-in-chief. Authors may appeal editorial decisions in case of rejection of articles.
Ranking as of November 2024
Derivation MethodRank | Company | Click Share |
---|---|---|
1 | FINAR |
22.4%
|
2 | Sinocompound |
10.2%
|
3 | Junsei Chemical Co.,Ltd. |
10.2%
|
4 | MDPI |
8.2%
|
5 | Actylis |
8.2%
|
6 | Varsal |
6.1%
|
7 | Hydrite Chemical Co. |
6.1%
|
8 | Kishida Chemical Co.,Ltd. |
6.1%
|
9 | Merck |
6.1%
|
10 | Toronto Research Chemicals |
4.1%
|
Derivation Method
The ranking is calculated based on the click share within the methanesulfonic acid page as of November 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
Country | Number of Companies | Share (%) |
---|---|---|
United States of America | 4 | 30.8% |
Japan | 4 | 30.8% |
Switzerland | 2 | 15.4% |
Canada | 1 | 7.7% |
China | 1 | 7.7% |
India | 1 | 7.7% |