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This section provides an overview for hexenal as well as their applications and principles. Also, please take a look at the list of 10 hexenal manufacturers and their company rankings. Here are the top-ranked hexenal companies as of December, 2024: 1.Flavor and Extract Manufacturers Association, 2.American Chemical Society.
Table of Contents
Figure 1. Basic Information on Trans-2-Hexenal
Hexenal, an organic compound with the formula C6H10O, includes isomers like trans-2-hexenal and cis-3-hexenal, also known as Aoba-Aldehydes. It has a molecular weight of 98.14 g/mol.
The isomers, notably trans-2-hexenal and cis-3-hexenal, contribute to grass and leaf fragrances, serving as flavoring agents. Although both have plant aromas, trans-2-hexenal is preferred for its aromatic quality over the unpleasant odor of cis-3-hexenal.
Trans-2-hexenal, a colorless to yellow liquid, melts at -39.8°C, boils at 146°C, and has a flash point of 43°C. It dissolves in acetone and ethanol but is nearly insoluble in water. Cis-3-hexenal boils at 126°C.
Figure 2. Basic Information on Cis-3-Hexenal
As aliphatic aldehydes, trans-2-hexenal and cis-3-hexenal have densities of 0.846 g/mL and 0.851 g/mL at 25°C, respectively. Cis-3-hexenal can isomerize to trans-2-hexenal, with its alcohol form, cis-3-hexen-1-ol, being a stable and commonly used fragrance.
The identity of tree fragrance during the fresh green season was first explored by Reinke around 1870 through essential oils. Theodor Curtius identified 2-hexenal in 1912, which Akinawa Hatanaka in 1960 confirmed as the same as the Aoba aldehyde from tea.
Trans-2-hexenal is found in various vegetables and fruits, making up the stink bug odor. Cis-3-hexenal, prevalent in many plants and used as a pheromone by insects, contributes to the aroma of tomatoes and other produce.
Figure 3. Synthesis of Hexenal
Trans-2-hexenal and cis-3-hexenal are synthesized from ethyl vinyl ether and 3-hexen-1-ol, respectively, with cis-3-hexenal also biosynthesized from linolenic acid.
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American Chemical Society is a scientific society with headquarters in Washington, D.C., United States. Founded in 1876, ACS has over 158,000 members and publishes over 70 peer-reviewed journals. The society's desire is to advance the chemical sciences. It does this by providing a forum for the exchange of ideas, supporting research, and promoting the education and professional development of chemists. ACS also provides unlimited resources to its members, including access to scientific information, career services, and networking opportunities.
Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
Flavor and Extract Manufacturers Association (FEMA), established in 1909 and located in Washington, District of Columbia, USA, consists of flavor manufacturers, flavor ingredients suppliers, and flavor users. The organization provides various flavors and spices to ensure a sustainable supply of flavoring ingredients. It also provides training, education, and resources necessary to capitalize on the opportunities in today's flavor industry. The organization operates a Flavor Ingredient Library, a handy resource for the media, researchers, and users seeking information on flavor ingredients that are generally recognized as safe (GRAS) for consumption.
StressMarq Biosciences Inc. is a manufacturer of research products for the life sciences and drug discovery and biopharma market bioreagents. The company is based in Victoria, British Columbia, Canada and was established in 2007. Its main activities include developing and commercialising a range of unique fibrilized and oligomeric protein preparations for use in neurodegenerative disease research. The company's main products include antibodies, proteins, kits, and small molecules as well as antibodies against alpha-synuclein, tau, and amyloid beta. StressMarq offers services such as training, and custom protein synthesis. Its products are used in many industries, including neuroscience, cancer research, and cell signalling.
Nacalai Tesque Inc., founded in 1846 and headquartered in Kyoto, Japan, is a manufacturer of research chemicals, fine chemicals, diagnostics, and the related instruments. Some of its products include cytokines, nucleic acid electrophoresis, cell dissociation reagents, and sialic acid-related products, and it also offers custom and bulk service for bulk reagents and cell culture media. The company has more than 50 domestic distributors and several worldwide, including Asia, the Middle East, Oceania, Europe, and Africa. It is ISO 9001 and ISO 9002 certified, while the Kyoto South brand and Tesque factory are ISO 14001 certified.
LARODAN AB is a provider of lipids and related products for research and industrial applications. With its headquarters in Malmö, Sweden, the company was established in 1963. LARODAN specializes in producing a wide range of lipids, including fatty acids, liposomes, and lipid standards. These products serve various sectors such as pharmaceuticals, life sciences, and food industries. The company offers services such as Packaging, delivery, Certificates of analysis, high-purity lipids, customized solutions, and technical expertise.
Environmental Working Group (EWG) is a not-for-profit consumer protection and environmental health organization based in Washington D.C. Founded in 1993, the organization engages in scientific analysis of various industrial and consumer products including pesticides, cosmetics, and food products, publishing their findings in quarterly reports and databases. The organization is actively engaged in a certification program for products and companies that meet their transparency and health standards, which are updated annually. Notable EWG projects include their Shopper's Guide to Pesticides in Produce, a state-by-state Tap Water Database, and nationwide campaigns promoting clean energy and advocating against citizens’ exposure to harmful chemicals.
CDN Isotopes Inc. has been a provider of deuterium-labelled compounds since its establishment in 1993. Located in Quebec, Canada, they supply researchers in the fields of medicine and science. They have over 3000 products and 98%of their orders are filled from stock. CDN isotopes have international distributors in over 40 countries and have continued to add new products to the market. They aim to provide customers with products at affordable prices while maintaining a large inventory of products.
Ernesto Ventós S.A. is a company that was established in 1916 in Sant Just Desvern, Spain, specializing in distributing aroma compounds and essential oils to the fragrance and flavoring industries. Ventós is a company that has established solid commercial partnerships with significant raw material producers. As a result, they have become a distinguished agent or distributor of goods for these producers. The company has a wide range of over three thousand products, allowing them to offer efficient just-in-time service to their clients.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | Flavor and Extract Manufacturers Association |
50.0%
|
| 2 | American Chemical Society |
50.0%
|
Derivation Method
The ranking is calculated based on the click share within the hexenal page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
Japan
|
2 | 33.3% |
|
United States of America
|
1 | 16.7% |
|
Sweden
|
1 | 16.7% |
|
Canada
|
1 | 16.7% |
|
Spain
|
1 | 16.7% |
