This section provides an overview for picric acids as well as their applications and principles. Also, please take a look at the list of 16 picric acid manufacturers and their company rankings. Here are the top-ranked picric acid companies as of November, 2024: 1.Ennore India Chemicals, 2.Aadhunik Industries, 3.KANTO CHEMICAL CO.,INC..
Table of Contents
Graduated from Hokkaido University Graduate School in 2013, Ph.D. (Science), postdoctoral researcher, foreign-affiliated chemical company, pharmaceutical manufacturing research and development, and currently freelancer.
Specializes in organic chemistry, synthetic chemistry, and pharmaceutical process chemistry.
linkedin: www.linkedin.com/in/naoto-kinashi-61209a172
Thesis
https://doi.org/10.1016/j.tetlet.2013.06.085
https://doi.org/10.1021/acs.orglett.7b03695
https://doi.org/10.1016/j.tetlet.2015.11.079
Picric acid, known as 2,4,6-trinitrophenol, is a nitro compound of phenol derivatives. It is a pale yellow crystal at room temperature, with a CAS number of 88-89-1, a melting point of 252.5°F, a density of 1.76 g/cm3, and an ignition point of 611.6°F. Picric acid is soluble in water and polar organic solvents but insoluble in non-polar solvents.
Picric acid is a strong acid due to the electron-withdrawing effect of its three nitro groups, with a pKa of 0.38 compared to phenol's 9.95. It is toxic, causing diarrhea and vomiting if ingested, and is explosive under heat or impact. Picric acid forms explosive salts with various metals and reacts with organic compounds to form picrates. Unlike typical phenols, picric acid does not react with iron(III) chloride due to reduced electron density in its benzene ring.
Historically used as a military explosive, picric acid's sensitivity to impact and friction and its tendency to form explosive salts with metals have reduced its use in explosives, replaced by TNT. Today, picric acid is used as an analytical reagent in biological tissue specimen preparation, acid-base indicator, and in fireworks, agrochemicals, dyes, and gas desulfurization catalysts.
Picric acid is synthesized by nitrating phenol, typically using the sulfophenol method to avoid oxidation. It can also be synthesized by hydrolyzing chlorodinitrobenzene. Picric acid is toxic and irritant; it must be handled with care, stored securely, and disposed of by licensed waste disposal companies.
*Including some distributors, etc.
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Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
Junsei Chemical Co. Ltd., established in 1948 and headquartered in Tokyo, Japan, is a manufacturer of chemical reagents and chemical products, including commissioned synthesis of chemical products. Some of the products it makes include Sodium chloride solution, concentrated glycerin, calcium chloride, ascorbic acid, and nitric acid. The chemical products have a wide range of applications and can be used in pathological examination, as food additives, for analysis, and in the pharmaceutical industry. All its plants, including its research institute, are ISO4001 and ISO9001 certified, while its Saitama and Ibaraki plants are equipped with buildings that comply with GMP.
Kishida Chemical Co. Ltd., established in 1924 and headquartered in Osaka, Japan, is a manufacturer of reagents and high-purity chemicals and also does drug discovery support activities. Its product portfolio includes fine chemicals, research chemicals, ionic liquid, organic micro-analytical reagents, and chemical reagents for analysis. The products support several industries, including reagent business, battery material, drug discovery, and life science. The company is ISO 14001 certified and supplies several companies worldwide, including Meterion Advanced Chemicals Inc., Acros Organics, ChemBridge Corporation, Decon Laboratories, and InerBioScreen Ltd.
Ennore India Chemicals, established in 1995, and based in Tamil Nadu, India, is a manufacturer and supplier of industrial chemicals and cleaning solutions. The company serves various industries, including wastewater treatment, marine, power generation, and oil and gas. Ennore India Chemicals also provides fuel additives, corrosion inhibitors, descaling chemicals, chemicals for boiler water treatment, as well as chemicals for cooling towers. Their ISO 9001:2015 certification guarantees quality goods and environmentally friendly practices.
A.B. Enterprises was established in 1984 and is headquartered in Maharashtra, India. The company is a manufacturer and supplier of general chemicals, specialties, and industrial chemicals to a broad range of industries including food, textile, plastic, rubber, and other industries. The company exports primarily to Canada, Bahrain, and Dubai. The company’s five major product segments include petrochemicals, food chemicals, laboratory chemicals, water treatment chemicals, and fine chemicals. In addition, the company manufactures dentistry materials, pesticides, and chemical supplies.
Indian Platinum Private Limited (IPP) is a manufacturer of precious metal chemicals, catalysts, and compounds established in 2009. Based in Mumbai, Maharashtra, the company offers various precious metal products including platinum chemicals, gold alloys, and cobalt salts, as well as specialty chemicals such as reagents and acid dyes. These are primarily used by clients in the pharmaceutical, chemical, and jewelry industries, as well as by electroplating and metal finishing service providers. In addition to its products, IPP also offers custom synthesis of metal compounds, as well as waste management and metal recovery services.
Alpha Chemika, founded in 1989 and based in Mumbai, India, is a manufacturer, supplier of laboratory reagents and fine chemicals. Their products are used in multiple industries, including pharmaceutical, chemical, biotechnology, and environmental. Their product portfolio ranges from chemicals such as Silver Nitrate, Perchloric Acid, and Lanthanum Acetate to laboratory tools and equipment such as Air Inlet Tubes, Air Inlet Tubes, and Optical Components. Alpha Chemika has been able to obtain ISO 9001:2000 certification.
Hefei TNJ Chemical Industry Co., Ltd, established in 2001, is headquartered in China. The company is a chemical manufacturer and supplier of chemicals to domestic Chinese and global consumers in four primary markets: chemicals, food, pharmaceuticals, and personal care. Chemicals include fine chemicals, agrochemicals, and other chemicals. Food includes agrochemicals, vitamins, amino acids, and food ingredients. Pharmaceuticals include specific chemicals such as Povidone iodine, Clotrimazole crystalline, and Lincomycin. The company also features a CAS databank for CAS-registered chemical compounds.
Suvidhinath Laboratories was founded in 1985 and is headquartered in Gujarat, India. The company is an ISO 9001-2008 certified exporter, manufacturer, trader, and supplier of laboratory chemicals and reagents to global customers, especially across South East Asia and the Gulf countries. The company’s client list includes Cadila Pharmaceuticals Limited, Gujarat State Fertilizers & Chemicals LTD, Deepak Nitrite Limited, and Indian OIl. The company’s product categories include food-grade chemicals, pharmaceutical chemicals, laboratory chemicals, and industrial chemicals.
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
Aadhunik Industries is a manufacturer and supplier of hydraulic fracturing chemicals, based in Mumbai, India. The company offer crystal granules in precise micron or mesh sizes according to buyers needs. These products are also available through its agents in the UAE and the USA. It also provides encapsulated gel breakers and low and high-temperature flow diverting agents for oil fracturing and drilling. The company and its associated units are FDA-GMP certified, Halal and Kosher certified, REACH registered, ISO-9001 certified, and ISO-22000 HACCP certified.
Sisco Research Laboratories Pvt. Ltd. was established in 1975 and is headquartered in Mumbai, Maharashtra, India. The company manufactures highly complex reagents and biochemicals for public and private customers across industries with over 5000 products in different grades and packing sizes across product segments. The company’s 6 product categories are General Laboratory Chemicals & Solvents, Biochemicals & Specialty Fine Chemicals, Animal Cell Culture, Nanotechnology Products, Dehydrated Culture Media & Media Kits, and Biolit™ range of DNA and Protein tools.
RX Chemicals was founded in Mumbai, India, in 2011. RX Chemicals sells chemical-based products for many sectors including automobile, agriculture, airline, medicine, and accessories. Automobile products include carwash shampoo, compressor cleaner, and interior cleaners. Agricultural products include fungicides, herbicides, and pesticides. Airline products include exterior products such as deicing fluid, as well as interior products such as solvent cleaner. The company also provides a range of services including chemical inspection, logistics, chemical usage supervision, as well as tank cleaning.
Founded in 1981, Central Drug House Ltd. serves the scientific community via manufacturing and marketing a library of over 9,000 products to laboratory fine chemicals and dehydrated culture media with emphasis on purity and service. Examples are acids & bases, adsorbents, disinfectants, indicator papers, oils, and solvents. CDH provides bio chemicals, research chemicals, laboratory reagents, various solvents, stains & indicators, and dehydrated culture media. CDH is ISO 9001 certified and CDHs’ products are in compliance with specifications of IP, BP, USP, and EP standards.
Founded in Mumbai, India in 2006, Otto Chemie Pvt. Ltd. is an ISO 9001:2015 & GMP certified chemical manufacturing company and distributor. Otto Chemie serves customers in many industries including agriculture and food processing, pharmaceuticals, oil & gas, cement, as well as educational and R&D industries. Product offerings include antibiotics, amino acids, vitamins, detergents, ionic liquids, materials science compounds, labware, oil, metal & ceramic science compounds and tools, oils, reagents, solvents.
Ranking as of November 2024
Derivation MethodRank | Company | Click Share |
---|---|---|
1 | MilliporeSigma |
16.1%
|
2 | Ennore India Chemicals |
14.5%
|
3 | Aadhunik Industries |
11.3%
|
4 | KANTO CHEMICAL CO.,INC. |
9.7%
|
5 | Alpha Chemika |
6.5%
|
6 | A. B. Enterprises |
6.5%
|
7 | Otto Chemie Pvt. Ltd |
6.5%
|
8 | Junsei Chemical Co.,Ltd. |
4.8%
|
9 | Kishida Chemical Co.,Ltd. |
4.8%
|
10 | INDIAN PLATINUM PRIVATE LIMITED |
3.2%
|
Derivation Method
The ranking is calculated based on the click share within the picric acid page as of November 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
Country | Number of Companies | Share (%) |
---|---|---|
India | 10 | 71.4% |
Japan | 3 | 21.4% |
China | 1 | 7.1% |