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This section provides an overview for biphenyl as well as their applications and principles. Also, please take a look at the list of 14 biphenyl manufacturers and their company rankings. Here are the top-ranked biphenyl companies as of December, 2024: 1.Alpha Chemika, 2.Labeyond Chemicals Co., Ltd., 3.Kishida Chemical Co.,Ltd..
Table of Contents
Biphenyl is an aromatic hydrocarbon consisting of two benzene rings joined by a single bond. It appears as a colorless or white solid and is almost insoluble in water but dissolves in acetone and alcohol. While some biphenyl derivatives have a wide range of applications, others are highly toxic and require careful handling and disposal.
Colorless or white crystalline substance, sometimes in flake form.
Insoluble in water, and soluble in organic solvents like acetone, ethanol, toluene, and xylene.
Biphenyl adopts a planar structure at room temperature but forms a twisted conformation when cooled below its phase transition temperature due to steric hindrance.
Biphenyl is used as a fungicide, synthetic resin, heat transfer medium, and raw material. In Japan, it is used less frequently in citrus fruits due to biphenyl-resistant bacteria. Biphenyl is also added to lithium-ion battery electrolytes as an overcharge inhibitor.
Polychlorinated biphenyls (PCBs), derivatives of biphenyl, were previously used in insulators, heat transfer media, and plasticizers but were banned due to their adverse health effects and environmental impact.
Biphenyl can be synthesized through various methods, including the Ullmann reaction, heating benzene in a red-hot tube, and photolysis of benzene bromide.
Biphenyl is an eye irritant and a carcinogen. Long-term exposure can affect the liver, kidney, and nervous system. Safety precautions, including protective gear, are necessary when handling biphenyl and its derivatives.
*Including some distributors, etc.
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Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
Junsei Chemical Co. Ltd., established in 1948 and headquartered in Tokyo, Japan, is a manufacturer of chemical reagents and chemical products, including commissioned synthesis of chemical products. Some of the products it makes include Sodium chloride solution, concentrated glycerin, calcium chloride, ascorbic acid, and nitric acid. The chemical products have a wide range of applications and can be used in pathological examination, as food additives, for analysis, and in the pharmaceutical industry. All its plants, including its research institute, are ISO4001 and ISO9001 certified, while its Saitama and Ibaraki plants are equipped with buildings that comply with GMP.
Kishida Chemical Co. Ltd., established in 1924 and headquartered in Osaka, Japan, is a manufacturer of reagents and high-purity chemicals and also does drug discovery support activities. Its product portfolio includes fine chemicals, research chemicals, ionic liquid, organic micro-analytical reagents, and chemical reagents for analysis. The products support several industries, including reagent business, battery material, drug discovery, and life science. The company is ISO 14001 certified and supplies several companies worldwide, including Meterion Advanced Chemicals Inc., Acros Organics, ChemBridge Corporation, Decon Laboratories, and InerBioScreen Ltd.
Alpha Chemika, founded in 1989 and based in Mumbai, India, is a manufacturer, supplier of laboratory reagents and fine chemicals. Their products are used in multiple industries, including pharmaceutical, chemical, biotechnology, and environmental. Their product portfolio ranges from chemicals such as Silver Nitrate, Perchloric Acid, and Lanthanum Acetate to laboratory tools and equipment such as Air Inlet Tubes, Air Inlet Tubes, and Optical Components. Alpha Chemika has been able to obtain ISO 9001:2000 certification.
Ennore India Chemicals, established in 1995, and based in Tamil Nadu, India, is a manufacturer and supplier of industrial chemicals and cleaning solutions. The company serves various industries, including wastewater treatment, marine, power generation, and oil and gas. Ennore India Chemicals also provides fuel additives, corrosion inhibitors, descaling chemicals, chemicals for boiler water treatment, as well as chemicals for cooling towers. Their ISO 9001:2015 certification guarantees quality goods and environmentally friendly practices.
Merck, started in 1668 and based in Darmstadt, Germany, is a supplier of solutions and services for research, development, and manufacture of pharmaceutical and biotechnological drug therapies. The company serves the life science industry and has a broad portfolio of 300,000 products, including biopharmaceutical manufacturing, industrial microbiology, reagent, life science research, and water purification products. It is available in 66 countries, brings together six brands, and has several ISO certifications, including ISO 13485, ISO 14001, ISO 13485, and ISO 50001.
Nacalai Tesque Inc., founded in 1846 and headquartered in Kyoto, Japan, is a manufacturer of research chemicals, fine chemicals, diagnostics, and the related instruments. Some of its products include cytokines, nucleic acid electrophoresis, cell dissociation reagents, and sialic acid-related products, and it also offers custom and bulk service for bulk reagents and cell culture media. The company has more than 50 domestic distributors and several worldwide, including Asia, the Middle East, Oceania, Europe, and Africa. It is ISO 9001 and ISO 9002 certified, while the Kyoto South brand and Tesque factory are ISO 14001 certified.
Taj Pharmaceuticals Limited, established in 1995 and headquartered in Mumbai, India, is a global manufacturer and supplier of generic medicines, healthcare, and other products. The company markets more than 500 branded and 4600 generic compositions to consumers in over 40 countries and territories across the globe. Its products cover a vast array of therapeutic categories, and offers an extensive range of dosage forms and delivery systems including oral solids, controlled-release, and steriles. Some of its offerings are diabetic care products, insulin, and growth hormones. The company holds the ISO 9001:2000 certification for its quality management system.
Eastman Chemical was founded in 1920 and is headquartered in Kingsport, Tennessee. The company is a manufacturer and distributor of specialty chemicals, including coatings, adhesives, fibers, and plastics for industries such as automotive, medical, manufacturing, and construction. The company operates through four segments: Additives & Functional Products, Advanced Materials, Chemical Intermediates, and Fibers segments. Additives & Functional Products include food and fertilizer-based products. Advanced Materials include films and other chemicals used in transportation and electronics. Chemicals include phthalate plasticizers and other plastic products. Fibers include cigarette filters and other products.
Founded in 1981, Central Drug House Ltd. serves the scientific community via manufacturing and marketing a library of over 9,000 products to laboratory fine chemicals and dehydrated culture media with emphasis on purity and service. Examples are acids & bases, adsorbents, disinfectants, indicator papers, oils, and solvents. CDH provides bio chemicals, research chemicals, laboratory reagents, various solvents, stains & indicators, and dehydrated culture media. CDH is ISO 9001 certified and CDHs’ products are in compliance with specifications of IP, BP, USP, and EP standards.
National Analytical Corporation (NAC) is located in Mumbai, India. NAC was founded in 2009 as a distributor of laboratory grade chemicals used in numerous industries. NAC’s chemical offerings include biochemical & reagents such s Prunetin and 1,2-dipalmitoly-rac-glycerol, analytical grade chemicals such as chicoric acid and Vitamin E solutions, laboratory chemicals such as formic acid and nitric acid, gas chromatography chemicals such as Aalborg mass flowmeter battery kits and DEX 225, reference standard chemicals such as Palladium in HNO3, oral solid dosage forms, such as cellulosic and protect film coating systems, parenteral dosage forms, beverage & nutrition, and coating chemicals.
Founded in Mumbai, India in 2006, Otto Chemie Pvt. Ltd. is an ISO 9001:2015 & GMP certified chemical manufacturing company and distributor. Otto Chemie serves customers in many industries including agriculture and food processing, pharmaceuticals, oil & gas, cement, as well as educational and R&D industries. Product offerings include antibiotics, amino acids, vitamins, detergents, ionic liquids, materials science compounds, labware, oil, metal & ceramic science compounds and tools, oils, reagents, solvents.
Ranking as of December 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | Alpha Chemika |
17.5%
|
| 2 | Labeyond Chemicals Co., Ltd. |
12.5%
|
| 3 | Kishida Chemical Co.,Ltd. |
10.0%
|
| 4 | Merck |
10.0%
|
| 5 | NATIONAL ANALYTICAL CORPORATION |
7.5%
|
| 6 | Central Drug House |
7.5%
|
| 7 | nacalai |
7.5%
|
| 8 | Ennore India Chemicals |
5.0%
|
| 9 | Taj Pharmaceuticals Limited |
5.0%
|
| 10 | Eastman Chemical Co. |
5.0%
|
Derivation Method
The ranking is calculated based on the click share within the biphenyl page as of December 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
India
|
6 | 54.5% |
|
Japan
|
4 | 36.4% |
China
|
1 | 9.1% |
